Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| NDST4 | 64579 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 | 4 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 23825612 | 2013 | Cell line : - Source : Cardinal Tien Hospital, Taiwan Sample Type : CRC tumor and normal tissue No. of Sample : 174 Stage : - | real time RT-PCR | Allele loss | - | The loss of heterozygosity assay, which was established to determine the allelic loss of NDST4 gene, could be a cost-effective tool for providing a useful biomarker of adverse prognosis in CRC. NDST4 gene is a novel candidate tumor suppressor gene in human cancer, and the loss of its function might be involved in CRC progression. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Sulfotransferases, membrane-bound |
| Description | - | Chromosome | 4 |
| Location | 4q26 |
| Start | 114827775 |
| End | 115113876 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 286102 |
| OMIM ID | 615039 |
| HGNC ID | HGNC:20779 |
| Unigene ID | Hs.591700 |
| Ensembl ID | ENSG00000138653 |
| PharmGKB ID | - |
mRNA Information
| mRNA ID | NM_022569.1 |
|---|---|
| Exon | join(1..433,36595..37818,136603..136690,143293..143447, 176374..176559,178543..178671,242927..243109, 261056..261152,265539..265662,267880..268054, 274329..274499,280162..280271,283985..284087, 285942..286102) | mRNA Sequence | Download Select all |
| Length | 3359 |
CDS Information
| Location | join(36841..37818,136603..136690,143293..143447, 176374..176559,178543..178671,242927..243109, 261056..261152,265539..265662,267880..268054, 274329..274499,280162..280271,283985..284087, 285942..286061) |
|---|---|
| CDS Sequence | Download Select all |
| CCDS ID | CCDS3706.1 |
Protein Information
| Protein ID | NP_072091.1 |
|---|---|
| Protein Name | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 |
| Molecular Wt. (Da) | 100585 |
| Protein Sequence | Download Select all |
| Length | 872 |
| Uniprot ID | Q08380 |
| Ensembl Protein ID | ENSP00000262776 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Glycosaminoglycan biosynthesis - heparan sulfate / heparin | hsa00534 |
| Metabolic pathways | hsa01100 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam12062 | 19-505 | HSNSD |
| cl13492 | 19-505 | HSNSD superfamily |
| pfam00685 | 594-845 | Sulfotransfer_1 |
| cl21551 | 594-845 | Sulfotransfer_1 superfamily |
| PLN03076 | 22-99 | PLN03076 |
Ontology Information
| HPRD ID | 3949 |
|---|---|
| Molecular Class | Transcription regulatory protein |
| Molecular Function | Cell adhesion molecule activity (GO:0005194) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.