Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| NTSR1 | 4923 | neurotensin receptor 1 (high affinity) | 20 | NTR |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 18541341 | 2008 | Cell line : - Source : - Sample Type : - No. of Sample : - Stage : - | In situ hybridization | Up-regulation | - | NTSR1 may thus be a potential target for preventive or therapeutic strategies in colon cancer. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | GPCR / Class A : Neurotensin receptors |
| Description | Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion. [provided by RefSeq, Jul 2008] | Chromosome | 20 |
| Location | 20q13 |
| Start | 61340189 |
| End | 61394123 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 53935 |
| OMIM ID | 162651 |
| HGNC ID | HGNC:8039 |
| Unigene ID | Hs.590869 |
| Ensembl ID | ENSG00000101188 |
| PharmGKB ID | PA31821 |
mRNA Information
| mRNA ID | XM_011528827.1 |
|---|---|
| Exon | join(1..1139,45903..46104,49484..49611,51236..51307) | mRNA Sequence | Download Select all |
| Length | 1541 |
Protein Information
| Protein ID | XP_011527129.1 |
|---|---|
| Protein Name | neurotensin receptor 1 (high affinity) |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 336 |
| Uniprot ID | Q93098 |
| Ensembl Protein ID | ENSP00000340677 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 409 | ARRB2 | 147 | NP_004304.1 | in vivo | 11279203 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Calcium signaling pathway | hsa04020 |
| Neuroactive ligand-receptor interaction | hsa04080 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam10323 | 159-381 | 7TM_GPCR_Srv |
| cl21561 | 159-381 | 7tm_4 superfamily |
| pfam00001 | 120-364 | 7tm_1 |
| PHA03087 | 63-371 | PHA03087 |
| PHA02638 | 66-405 | PHA02638 |
Ontology Information
| HPRD ID | 4741 |
|---|---|
| Molecular Class | G protein coupled receptor |
| Molecular Function | Receptor binding (GO:0005102) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.