Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| OPCML | 4978 | opioid binding protein/cell adhesion molecule-like | 11 | OPCM, OBCAM, IGLON1 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 23471507 | 2013 | Cell line : - Source : - Sample Type : CRC tumor and normal tissue No. of Sample : 6 pairs of CRC and adjacent normal mucosa Stage : - | Microarray | Hypermethylation | - | Through Preliminary validation, there were two genes (St3gal6, Opcml) in thirty top-ranking genes shown hypermethylated in six pairs of CRC and adjacent normal mucosa. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Immunoglobulin superfamily / I-set domain containing |
| Description | This gene encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily. The encoded protein is localized in the plasma membrane and may have an accessory role in opioid receptor function. This gene has an ortholog in rat and bovine. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the encoded protein is highly conserved in species during evolution, it may have a fundamental role in mammalian systems. Two transcript variants encoding different isoforms have been found for this gene. | Chromosome | 11 |
| Location | 11q25 |
| Start | 132414981 |
| End | 133532508 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 1117528 |
| OMIM ID | 600632 |
| HGNC ID | HGNC:8143 |
| Unigene ID | Hs.4817 |
| Ensembl ID | ENSG00000183715 |
| PharmGKB ID | - |
mRNA Information
| mRNA ID | NM_001012393.1 |
|---|---|
| Exon | join(1..245,589499..589583,875190..875422, 1003323..1003448,1095150..1095287,1095730..1095850, 1096272..1096423,1112216..1117528) | mRNA Sequence | Download Select all |
| Length | 6413 |
CDS Information
| Location | join(185..245,589499..589583,875190..875422, 1003323..1003448,1095153..1095287,1095730..1095850, 1096272..1096423,1112216..1112316) |
|---|---|
| CDS Sequence | Download Select all |
| CCDS ID | - |
Protein Information
| Protein ID | NP_002536.1 |
|---|---|
| Protein Name | opioid binding protein/cell adhesion molecule-like |
| Molecular Wt. (Da) | 34705 |
| Protein Sequence | Download Select all |
| Length | 345 |
| Uniprot ID | P54868 |
| Ensembl Protein ID | ENSP00000358414 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 5621 | PRNP | 1453 | NP_000302.1 | in vivo | 15146195 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd05717 | 44-132 | Ig1_Necl-1-3_like |
| cl11960 | 44-132 | Ig superfamily |
| cd05750 | 241-311 | Ig_Pro_neuregulin |
| cl11960 | 241-311 | Ig superfamily |
| cd00096 | 241-310 | Ig |
| pfam00047 | 237-298 | ig |
| cd05882 | 44-119 | Ig1_Necl-1 |
| cd05732 | 224-311 | Ig5_NCAM-1_like |
| cd05730 | 211-311 | Ig3_NCAM-1_like |
| cd05730 | 135-206 | Ig3_NCAM-1_like |
| cl11960 | 135-206 | Ig superfamily |
| cd07701 | 44-132 | Ig1_Necl-3 |
| pfam13895 | 234-311 | Ig_2 |
| cd05746 | 153-206 | Ig4_Peroxidasin |
| pfam13927 | 223-300 | Ig_3 |
| cd05870 | 224-311 | Ig5_NCAM-2 |
| pfam13895 | 135-220 | Ig_2 |
| cd05870 | 134-208 | Ig5_NCAM-2 |
| cd05732 | 134-206 | Ig5_NCAM-1_like |
| cd05773 | 210-311 | Ig8_hNephrin_like |
| cd05869 | 224-311 | Ig5_NCAM-1 |
| cd00096 | 153-208 | Ig |
| cd05856 | 236-308 | Ig2_FGFRL1-like |
| cd05764 | 237-311 | Ig_2 |
| cd05743 | 150-206 | Ig_Perlecan_D2_like |
| cd07693 | 223-309 | Ig1_Robo |
| cd05731 | 242-310 | Ig3_L1-CAM_like |
| cd04976 | 242-311 | Ig2_VEGFR |
| cd05881 | 43-147 | Ig1_Necl-2 |
| cd05724 | 143-220 | Ig2_Robo |
| cd05747 | 134-200 | Ig5_Titin_like |
| cd05728 | 225-311 | Ig4_Contactin-2-like |
| cd04968 | 135-206 | Ig3_Contactin_like |
| pfam13927 | 135-206 | Ig_3 |
| cd07693 | 135-206 | Ig1_Robo |
| cd05895 | 241-311 | Ig_Pro_neuregulin-1 |
| cd05729 | 234-311 | Ig2_FGFR_like |
| cd05851 | 135-206 | Ig3_Contactin-1 |
| cd04969 | 237-311 | Ig5_Contactin_like |
| cd04978 | 237-304 | Ig4_L1-NrCAM_like |
| cd05852 | 237-311 | Ig5_Contactin-1 |
| cd05728 | 143-206 | Ig4_Contactin-2-like |
| cd05856 | 150-210 | Ig2_FGFRL1-like |
| pfam13895 | 45-132 | Ig_2 |
| cd05738 | 244-303 | Ig2_RPTP_IIa_LAR_like |
| pfam00047 | 150-204 | ig |
| cd05745 | 149-210 | Ig3_Peroxidasin |
| cd05740 | 224-308 | Ig_CEACAM_D4 |
| cd05848 | 238-303 | Ig1_Contactin-5 |
| cd05857 | 242-311 | Ig2_FGFR |
| cd05725 | 242-311 | Ig3_Robo |
| cd04977 | 234-305 | Ig1_NCAM-1_like |
| cd04978 | 150-206 | Ig4_L1-NrCAM_like |
| cd05866 | 234-311 | Ig1_NCAM-2 |
| cd05760 | 241-311 | Ig2_PTK7 |
| cd04967 | 239-303 | Ig1_Contactin |
| cd05894 | 229-311 | Ig_C5_MyBP-C |
| cd05758 | 223-311 | Ig5_KIRREL3-like |
| cd05737 | 242-311 | Ig_Myomesin_like_C |
| cd05739 | 150-206 | Ig3_RPTP_IIa_LAR_like |
| cd05869 | 134-208 | Ig5_NCAM-1 |
| cd05892 | 242-303 | Ig_Myotilin_C |
| cd04969 | 150-207 | Ig5_Contactin_like |
| cd05739 | 242-308 | Ig3_RPTP_IIa_LAR_like |
| cd05876 | 153-206 | Ig3_L1-CAM |
| cd05863 | 242-311 | Ig2_VEGFR-3 |
| cd05733 | 241-303 | Ig6_L1-CAM_like |
| cd05731 | 153-206 | Ig3_L1-CAM_like |
| cd05715 | 99-132 | Ig_P0-like |
| cd05725 | 153-214 | Ig3_Robo |
| cd05747 | 226-311 | Ig5_Titin_like |
| cd05743 | 237-303 | Ig_Perlecan_D2_like |
| cd05746 | 242-311 | Ig4_Peroxidasin |
| cd05718 | 269-311 | Ig1_PVR_like |
| cd05898 | 223-311 | Ig5_KIRREL3 |
| cd05876 | 241-303 | Ig3_L1-CAM |
| cd05736 | 242-303 | Ig2_Follistatin_like |
| cd05726 | 150-220 | Ig4_Robo |
| cd04972 | 142-220 | Ig_TrkABC_d4 |
| cd04971 | 281-310 | Ig_TrKABC_d5 |
| cd05862 | 237-312 | Ig1_VEGFR |
| cd05757 | 253-310 | Ig2_IL1R_like |
| cd05741 | 50-134 | Ig_CEACAM_D1_like |
| cd00096 | 53-129 | Ig |
| cd04972 | 230-311 | Ig_TrkABC_d4 |
| cd05734 | 153-216 | Ig7_DSCAM |
| cd05763 | 155-206 | Ig_1 |
| cd04968 | 228-303 | Ig3_Contactin_like |
| cd05723 | 153-208 | Ig4_Neogenin |
| cd05748 | 160-220 | Ig_Titin_like |
| cd05744 | 242-303 | Ig_Myotilin_C_like |
| cd05887 | 279-311 | Ig1_Nectin-3_like |
| cd05891 | 145-221 | Ig_M-protein_C |
| cd05771 | 99-157 | IgC_Tapasin_R |
| cd05729 | 150-206 | Ig2_FGFR_like |
| cd05846 | 50-133 | Ig1_MRC-OX-2_like |
| smart00410 | 234-312 | IG_like |
| smart00408 | 149-206 | IGc2 |
| smart00410 | 44-132 | IG_like |
| smart00409 | 234-312 | IG |
| pfam07679 | 223-311 | I-set |
| pfam07679 | 136-208 | I-set |
| smart00408 | 237-303 | IGc2 |
| smart00409 | 44-132 | IG |
| smart00410 | 142-207 | IG_like |
| smart00409 | 142-207 | IG |
| pfam07679 | 38-132 | I-set |
| PHA02785 | 100-216 | PHA02785 |
Ontology Information
| HPRD ID | 3022 |
|---|---|
| Molecular Class | Adhesion molecule |
| Molecular Function | RNA binding (GO:0003723) |
| Biological Process | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219) |
Drug Information
No matching records could be found.