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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
ORAI2 80228 ORAI calcium release-activated calcium modulator 2  7CBCIP2, FLJ12474, FLJ14733, H_NH0514P08.8 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
25143380   2014Cell line : -

Source : -

Sample Type : -

No. of Sample : -

Stage : -

-Up-regulation-Tumor cells display increased expression of TRPC1, ORAI1, ORAI2, ORAI3, and STIM1.


Gene Details



NC_000007.13 (102073977..102097268)

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Gene Type protein coding
Gene Family ORAI calcium release-activated calcium modulators
Description -  
Chromosome 7
Location 7q22.1
Start 102073977  
End 102097268  
Strand +  
Gene Sequence

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Length 23292  
OMIM ID 610929   
HGNC ID HGNC:21667   
Unigene ID Hs.363308   
Ensembl ID ENSG00000160991   
PharmGKB ID PA162398454   

mRNA Information


mRNA ID ?NM_001126340.2
Exon  
mRNA Sequence

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Length  



CDS Information


   
Location
CDS Sequence

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CCDS ID CCDS5722.1



Protein Information


      
Protein IDNP_001119812.1
Protein NameORAI calcium release-activated calcium modulator 2
Molecular Wt. (Da)0
Protein Sequence

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Length 254  
Uniprot IDQ969G9
Ensembl Protein ID ENSP00000268459  



Post-translational Modification Information (Source : HPRD)


No matching records could be found.

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

No matching records from HPRD source could be found.

Pathway Information


      
Pathway Name Pathway ID
Calcium signaling pathway hsa04020


Structure Information


No matching records could be found.

Domain Information




ID Location Description
pfam0785643-231  Orai-1
cl0675243-231  Orai-1 superfamily


Ontology Information


   
HPRD ID5897
Molecular ClassUnclassified
Molecular FunctionReceptor binding (GO:0005102)
Biological ProcessCell communication (GO:0007154); Signal transduction (GO:0007165)  



SNP Information


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Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO