Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| PAGE4 | 9506 | P antigen family, member 4 (prostate associated) | X | PAGE-4, CT16.7 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
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Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 20010347 | 2010 | Cell line : - Source : - Sample Type : CRC tumor and normal tissue No. of Sample : 288 Stage : TNM Stage I-IV | Pearson chi2 and multiple logistic regression analyses | Up-regulation | - | A new predictive panel including PAGE4 expression may help predict liver metastasis of colorectal cancer. |
| 26317029 | 2014 | Cell line : - Source : Rasol Akram Hospital in Tehran. Sample Type : - No. of Sample : 90 Stage : TNM StageII, III,IV | RT-PCR | Up-regulation | - | The frequency of PAGE4 and SCP-1 genes expression was significantly higher in the primary tumours with liver metastasis when statistically compared with primary tumors with no liver metastasis. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | This gene is a member of the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in prostate and prostate cancer. It is also expressed in other male and female reproductive tissues including testis, fallopian tube, uterus, and placenta, as well as in testicular cancer and uterine cancer. The protein encoded by this gene shares sequence similarity with other GAGE/PAGE proteins, and also belongs to a family of CT (cancer-testis) antigens. The protein may play a role in benign and malignant prostate diseases. A related pseudogene is located on chromosome 7. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] | Chromosome | X |
| Location | Xp11.23 |
| Start | 49593863 |
| End | 49598572 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 4710 |
| OMIM ID | 300287 |
| HGNC ID | HGNC:4108 |
| Unigene ID | Hs.441038 |
| Ensembl ID | ENSG00000101951 |
| PharmGKB ID | PA28523 |
Protein Information
| Protein ID | NP_008934.1 |
|---|---|
| Protein Name | P antigen family, member 4 (prostate associated) |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 102 |
| Uniprot ID | Q9NZN5 |
| Ensembl Protein ID | ENSP00000349056 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
No STRING Network could be found.
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Ontology Information
| HPRD ID | 6837 |
|---|---|
| Molecular Class | MHC complex protein |
| Molecular Function | Deacetylase activity (GO:0019213) |
| Biological Process | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219) |
Drug Information
No matching records could be found.