CoReCG

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
23811286	2013	Cell line : - Source : - Sample Type : - No. of Sample : - Stage : -	-	Up-regulation	-	PAK1 stimulates CRC survival by up-regulation of HIF-1?.
25791829	2015	Cell line : - Source : - Sample Type : - No. of Sample : - Stage : -	TaqMan real-time polymerase chain reaction and immunohistochemistry and clinical analysis.	Up-regulation	-	PAK1 and PAK4 expression were associated with colorectal cancer metastasis and infiltration, PAK1 high expression may indicate poor prognosis of colorectal cancer.

Gene Details

NC_000011.9 (77033060..77185108, complement)
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Gene Type	protein coding
Gene Family	-
Description	This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]
Chromosome	11
Location	11q13-q14
Start	77033060
End	77185108
Strand	-
Gene Sequence	Download Select all
Length	152049
OMIM ID	602590
HGNC ID	HGNC:8590
Unigene ID	Hs.435714
Ensembl ID	-
PharmGKB ID	PA32917

mRNA Information

mRNA ID	XM_011545083.1
Exon	join(1..512,81526..81733,94070..94170,94676..94823, 99699..99736,115047..115166,118222..118396,120465..120528, 124777..124825,130133..130245,133301..133418, 136641..136740,137782..137978,141197..141334, 148688..148736,150704..152513)
mRNA Sequence	Download Select all
Length	3940

CDS Information

Location	531..2192
CDS Sequence	Download Select all
CCDS ID	CCDS44687.1

Protein Information

Protein ID	XP_011543385.1
Protein Name	p21 protein (Cdc42/Rac)-activated kinase 1
Molecular Wt. (Da)	51439
Protein Sequence	Download Select all
Length	553
Uniprot ID	Q14191
Ensembl Protein ID	ENSP00000298139

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
S	Phosphorylation	220
S	Phosphorylation	223
S	Phosphorylation	220
S	Phosphorylation	223
T	Phosphorylation	423
S	Phosphorylation	144
S	Phosphorylation	149
S	Phosphorylation	199
S	Phosphorylation	204
S	Phosphorylation	21
S	Phosphorylation	57
S	Phosphorylation	144
S	Phosphorylation	149
S	Phosphorylation	199
S	Phosphorylation	204
S	Phosphorylation	21
S	Phosphorylation	57
T	Phosphorylation	423
T	Phosphorylation	84
T	Phosphorylation	84
T	Phosphorylation	212
T	Phosphorylation	212
T	Phosphorylation	212
S	Phosphorylation	165
T	Phosphorylation	230
T	Phosphorylation	230
T	Phosphorylation	225
T	Phosphorylation	229
T	Phosphorylation	225
T	Phosphorylation	229
K	Acetylation	245
K	Acetylation	245
S	Acetylation	2
K	Acetylation	256
K	Acetylation	256
K	Acetylation	29
S	Phosphorylation	174
S	Phosphorylation	174

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING) View

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
58	ACTA1	30	NP_001091.1	in vivo	9298982
572	BAD	4409	NP_004313.1	in vitro	106 112 231 578 462 000 000 000
660	BMX	2111	NP_975010.1	in vitro;in vivo	11382770
668	FOXL2	5723	NP_075555.1	in vitro;in vivo	12560069
834	CASP1	977	NP_150634.1	in vitro;in vivo	15561713
985	CDC2L2	308	NP_277073.1	in vitro;in vivo;yeast 2-hybrid	12624090
998	CDC42	309	NP_001782.1	in vitro	97 052 807 744 004 800 000 000 000 000
1277	COL1A1	362	NP_000079.2	in vitro	10772928
1457	CSNK2A1	277	NP_001886.1	in vivo	10938077
1459	CSNK2A2	279	NP_001887.1	in vivo	10938077
2064	ERBB2	1281	NP_004439.2	in vivo	9774445
2099	ESR1	589	NP_000116.2	in vitro;in vivo	12374744
2308	FOXO1	645	NP_002006.2	in vivo	1 035 801 412 560 060
2316	FLNA	2060	NP_001104026.1	in vitro;in vivo;yeast 2-hybrid	12198493
3984	LIMK1	3210	NP_002305.1	in vitro;in vivo	105 599 361 065 235 000 000 000
4086	SMAD1	3356	NP_005891.1	in vivo	15761153
4087	SMAD2	3221	NP_005892.1	in vivo	15761153
4089	SMAD4	2995	NP_005350.1	in vivo	15761153
4638	MYLK	2952	NP_444253.3	in vitro;in vivo	10092231
4690	NCK1	2740	NP_006144.1	in vitro;in vivo	10 330 411 882 420 100 000 000
4771	NF2	6980	NP_000259.1	in vitro;in vivo	1 458 033 611 719 500
5335	PLCG1	1398	NP_002651.2	in vitro;in vivo	12085993
5580	PRKCD	1501	NP_006245.2	in vivo	16033904
5604	MAP2K1	1469	NP_002746.1	in vitro;in vivo	9351825
5829	PXN	3937	BAA18998.1	in vitro	10330411
5879	RAC1	3627	NP_061485.1	in vitro;in vivo	1 113 402 281 077 740 000 000 000 000 000 000 000 000 000 000
5894	RAF1	1265	NP_002871.1	in vitro;in vivo	11 733 498 923 470 800 000 000 000 000 000 000 000
6853	SYN1	2433	NP_008881.2	in vitro	12237306
7046	TGFBR1	1822	NP_004603.1	in vivo	15761153
7048	TGFBR2	1823	NP_001020018.1	in vivo	15761153
9181	ARHGEF2	10458	NP_001155855.1	in vitro	14970201
9459	ARHGEF6	2226	NP_004831.1	in vitro;in vivo	965 991 515 688 026
9815	GIT2	9779	NP_476510.1	in vitro;in vivo	11157752
10095	ARPC1B	10366	NP_005711.1	in vitro;in vivo	14749719
10818	FRS2	6372	NP_006645.3	in vitro	12154000
57154	SMURF1	6902	NP_065162.1	in vivo	15761153
58480	RHOU	6965	NP_067028.1	in vitro	15556869

Pathway Information

Pathway Name	Pathway ID
Axon guidance	hsa04360
cAMP signaling pathway	hsa04024
Chemokine signaling pathway	hsa04062
Epithelial cell signaling in Helicobacter pylori infection	hsa05120
ErbB signaling pathway	hsa04012
Fc gamma R-mediated phagocytosis	hsa04666
Focal adhesion	hsa04510
MAPK signaling pathway	hsa04010
Natural killer cell mediated cytotoxicity	hsa04650
Proteoglycans in cancer	hsa05205
Ras signaling pathway	hsa04014
Regulation of actin cytoskeleton	hsa04810
Renal cell carcinoma	hsa05211
T cell receptor signaling pathway	hsa04660

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
cd06654	249-544	STKc_PAK1
cl21453	249-544	PKc_like superfamily
cd01093	73-118	CRIB_PAK_like
cl00113	73-118	CRIB superfamily
cd06656	250-544	STKc_PAK3
cd06647	262-522	STKc_PAK_I
cd06655	250-544	STKc_PAK2
cd06614	269-522	STKc_PAK
cd05122	269-521	PKc_STE
cd06648	262-522	STKc_PAK_II
cd06659	248-541	STKc_PAK6
cd06609	268-534	STKc_MST3_like
cd06658	247-534	STKc_PAK5
cd06657	249-534	STKc_PAK4
cd06613	269-520	STKc_MAP4K3_like
cd06612	266-521	STKc_MST1_2
cd06606	269-521	STKc_MAPKKK
cd06610	268-520	STKc_OSR1_SPAK
cd06608	265-521	STKc_myosinIII_N_like
cd06627	269-521	STKc_Cdc7_like
cd06917	270-535	STKc_NAK1_like
cd06611	276-530	STKc_SLK_like
cd06642	265-538	STKc_STK25
cd06607	268-521	STKc_TAO
cd00180	276-518	PKc
cd06640	265-534	STKc_MST4
cd06643	265-538	STKc_SLK
cd06641	265-534	STKc_MST3
cd05117	269-520	STKc_CAMK
cd06638	258-521	STKc_myosinIIIA_N
cd06646	265-521	STKc_MAP4K5
cd06644	265-538	STKc_STK10
cd08215	269-521	STKc_Nek
cd06633	265-542	STKc_TAO3
cd06645	265-521	STKc_MAP4K3
cd06626	275-521	STKc_MEKK4
cd14014	269-517	STKc_PknB_like
cd06636	260-521	STKc_MAP4K4_6_N
cd06623	275-522	PKc_MAPKK_plant_like
cd06625	276-520	STKc_MEKK3_like
cd06639	262-522	STKc_myosinIIIB_N
cd14007	273-522	STKc_Aurora
cd06635	265-542	STKc_TAO1
cd05123	276-520	STKc_AGC
cd06634	265-542	STKc_TAO2
cd06632	269-521	STKc_MEKK1_plant
cd06631	270-521	STKc_YSK4
cd06628	269-521	STKc_Byr2_like
cd14003	274-518	STKc_AMPK-like
cd06637	265-522	STKc_TNIK
cd13999	276-517	STKc_MAP3K-like
cd14002	269-521	STKc_STK36
cd08217	269-521	STKc_Nek2
smart00750	350-529	KIND
cd06624	276-521	STKc_ASK
cd06629	269-521	STKc_Bck1_like
cd14008	276-521	STKc_LKB1_CaMKK
cd07833	269-521	STKc_CDKL
cd06605	276-522	PKc_MAPKK
cd13968	276-409	PKc_like
cd13983	269-521	STKc_WNK
cd05579	276-522	STKc_MAST_like
cd07829	270-521	STKc_CDK_like
cd06630	270-518	STKc_MEKK1
cd08529	274-521	STKc_FA2-like
cd14099	268-521	STKc_PLK
cd05118	270-521	STKc_CMGC
cd14095	269-518	STKc_DCKL
cd14009	276-520	STKc_ATG1_ULK_like
cd05581	274-520	STKc_PDK1
cd08216	275-536	PK_STRAD
cd14181	268-521	STKc_PhKG2
cd14081	275-521	STKc_BRSK1_2
cd06652	276-520	STKc_MEKK2
cd07841	269-522	STKc_CDK7
cd07847	269-520	STKc_CDKL1_4
cd14006	276-519	STKc_MLCK-like
cd14093	269-521	STKc_PhKG
cd06653	276-520	STKc_MEKK3_like_u1
cd05578	276-521	STKc_Yank1
cd14098	269-518	STKc_Rad53_Cds1
cd05573	273-522	STKc_ROCK_NDR_like
cd05580	273-509	STKc_PKA_like
cd08530	275-519	STKc_CNK2-like
cd14084	268-521	STKc_Chk2
cd06621	268-525	PKc_Pek1_like
cd14083	267-518	STKc_CaMKI
cd07832	269-521	STKc_CCRK
cd06651	270-523	STKc_MEKK3
cd00192	274-522	PTKc
cd08528	270-509	STKc_Nek10
cd07830	270-521	STKc_MAK_like
cd14010	270-520	STKc_ULK4
cd13985	276-517	STKc_GAK_like
cd14131	268-521	PKc_Mps1
cd14091	270-529	STKc_RSK_C
cd08220	269-518	STKc_Nek8
cd14069	276-521	STKc_Chk1
cd14086	268-522	STKc_CaMKII
cd14121	274-520	STKc_ULK3
cd07840	270-520	STKc_CDK9_like
cd14167	267-521	STKc_CaMKI_alpha
cd06617	274-525	PKc_MKK3_6
cd07846	269-520	STKc_CDKL2_3
cd14103	276-521	STKc_MLCK
cd08224	275-517	STKc_Nek6_7
cd14184	268-518	STKc_DCKL2
cd05572	276-520	STKc_cGK
cd14182	268-522	STKc_PhKG1
cd14078	267-521	STKc_MELK
cd14185	276-518	STKc_DCKL3
cd14072	269-521	STKc_MARK
cd05599	273-522	STKc_NDR_like
cd14663	269-518	STKc_SnRK3
cd14166	267-521	STKc_CaMKI_gamma
cd08222	269-521	STKc_Nek11
cd05570	276-522	STKc_PKC
cd14096	270-521	STKc_RCK1-like
cd06620	275-524	PKc_Byr1_like
cd08225	269-521	STKc_Nek5
cd05595	276-521	STKc_PKB_beta
cd14202	267-521	STKc_ULK1
cd05611	276-522	STKc_Rim15_like
cd14209	270-509	STKc_PKA
cd05612	270-534	STKc_PRKX_like
cd13994	276-521	STKc_HAL4_like
cd05584	276-522	STKc_p70S6K
cd07838	270-521	STKc_CDK4_6_like
cd14004	269-521	STKc_PASK
cd13993	269-517	STKc_Pat1_like
cd06618	272-528	PKc_MKK7
cd14175	270-541	STKc_RSK1_C
cd14120	276-520	STKc_ULK1_2-like
cd14169	270-518	STKc_CaMKI_beta
cd14114	270-521	STKc_Twitchin_like
cd14137	266-522	STKc_GSK3
cd06616	274-523	PKc_MKK4
cd06622	274-522	PKc_PBS2_like
cd13995	276-521	STKc_MAP3K8
cd14080	270-521	STKc_TSSK-like
cd05601	276-520	STKc_CRIK
cd14073	272-518	STKc_NUAK
cd14079	270-521	STKc_AMPK_alpha
cd14012	323-520	PK_eIF2AK_GCN2_rpt1
cd14106	274-521	STKc_DRAK
cd14133	274-521	PKc_DYRK_like
cd07836	270-520	STKc_Pho85
cd14119	276-518	STKc_LKB1
cd14201	263-522	STKc_ULK2
cd14087	269-521	STKc_PSKH1
cd14178	274-521	STKc_RSK3_C
cd08221	276-521	STKc_Nek9
cd14085	270-522	STKc_CaMKIV
cd14094	266-522	STKc_CASK
cd08228	274-517	STKc_Nek6
cd14019	268-521	STKc_Cdc7
cd14190	274-521	STKc_MLCK2
cd08218	269-521	STKc_Nek1
cd05575	276-520	STKc_SGK
cd05593	276-521	STKc_PKB_gamma
cd07835	270-521	STKc_CDK1_CdkB_like
cd14210	272-521	PKc_DYRK
cd07834	269-523	STKc_MAPK
cd05571	276-520	STKc_PKB
cd14059	276-524	STKc_MAP3K12_13
cd14070	275-521	STKc_HUNK
cd06619	274-521	PKc_MKK5
cd14118	276-518	STKc_CAMKK
cd14005	275-519	STKc_PIM
cd14177	270-521	STKc_RSK4_C
cd13996	274-458	STKc_EIF2AK
cd14077	274-521	STKc_Kin1_2
cd05594	251-521	STKc_PKB_alpha
cd13989	276-469	STKc_IKK
cd07845	271-527	STKc_CDK10
cd14183	268-521	STKc_DCKL1
cd14168	263-521	STKc_CaMKI_delta
cd05609	273-520	STKc_MAST
cd14116	276-521	STKc_Aurora-A
cd14186	276-521	STKc_PLK4
cd07860	270-520	STKc_CDK2_3
cd05591	276-468	STKc_nPKC_epsilon
cd14162	270-518	STKc_TSSK4-like
cd14097	268-521	STKc_STK33
cd14189	268-521	STKc_PLK3
cd14074	274-521	STKc_SNRK
cd14075	275-521	STKc_NIM1
cd14197	275-521	STKc_DRAK1
cd14161	267-464	STKc_NUAK2
cd08223	270-521	STKc_Nek4
cd14187	265-521	STKc_PLK1
cd14082	274-518	STKc_PKD
cd14221	276-515	STKc_LIMK1
cd14058	276-517	STKc_TAK1
cd14089	274-518	STKc_MAPKAPK
cd13979	274-516	STKc_Mos
cd07843	270-520	STKc_CDC2L1
cd05598	270-522	STKc_LATS
cd14188	268-521	STKc_PLK2
cd14192	274-521	STKc_MLCK3
cd05592	276-522	STKc_nPKC_theta_like
cd14060	277-516	STKc_MLTK
cd14165	276-521	STKc_TSSK1_2-like
cd05603	276-521	STKc_SGK2
cd14194	270-521	STKc_DAPK1
cd13997	272-518	PKc_Wee1_like
cd14061	276-517	STKc_MLK
cd05619	276-522	STKc_nPKC_theta
cd14176	270-521	STKc_RSK2_C
cd05589	276-522	STKc_PKN
cd14154	276-465	STKc_LIMK
cd14066	276-517	STKc_IRAK
cd05590	276-522	STKc_nPKC_eta
cd05583	276-522	STKc_MSK_N
cd07851	268-522	STKc_p38
cd14198	274-521	STKc_DRAK2
cd05620	276-522	STKc_nPKC_delta
cd06650	273-522	PKc_MEK1
cd05610	268-521	STKc_MASTL
cd14199	269-518	STKc_CaMKK2
cd05602	265-521	STKc_SGK1
cd06615	273-524	PKc_MEK
cd05585	276-521	STKc_YPK1_like
cd14071	276-521	STKc_SIK
cd13990	269-520	STKc_TLK
cd14062	276-517	STKc_Raf
cd14105	270-518	STKc_DAPK
cd05577	276-522	STKc_GRK
cd14065	276-518	PKc_LIMK_like
cd07850	269-523	STKc_JNK
cd14076	276-521	STKc_Kin4
cd07865	265-520	STKc_CDK9
cd14191	270-521	STKc_MLCK1
cd07855	270-522	STKc_ERK5
cd14115	276-518	STKc_Kalirin_C
cd14088	284-521	STKc_CaMK_like
cd14193	274-521	STKc_MLCK4
cd05629	276-522	STKc_NDR_like_fungal
cd14117	276-522	STKc_Aurora-B_like
cd05587	276-468	STKc_cPKC
cd05604	276-468	STKc_SGK3
cd14195	270-523	STKc_DAPK3
cd07831	275-520	STKc_MOK
cd07863	269-521	STKc_CDK4
cd08226	283-525	PK_STRAD_beta
cd14196	274-521	STKc_DAPK2
cd08219	269-464	STKc_Nek3
cd14171	274-521	STKc_MAPKAPK5
cd13991	275-515	STKc_NIK
cd14039	276-466	STKc_IKK_alpha
cd07852	268-522	STKc_MAPK15-like
cd07878	262-521	STKc_p38beta
cd05600	241-522	STKc_Sid2p_like
cd14090	274-518	STKc_Mnk
cd05041	274-517	PTKc_Fes_like
cd14046	270-519	STKc_EIF2AK4_GCN2_rpt2
cd05626	270-521	STKc_LATS2
cd07856	269-521	STKc_Sty1_Hog1
cd14033	269-521	STKc_WNK4
cd14111	266-469	STKc_SPEG_rpt2
cd05574	271-522	STKc_phototropin_like
cd14031	266-521	STKc_WNK3
cd14665	269-520	STKc_SnRK2-3
cd14107	270-521	STKc_obscurin_rpt1
cd13986	270-518	STKc_16
cd14036	276-524	STKc_GAK
cd05596	276-467	STKc_ROCK
cd08229	274-509	STKc_Nek7
cd07861	269-521	STKc_CDK1_euk
cd05616	276-468	STKc_cPKC_beta
cd07864	269-521	STKc_CDK12
cd14222	276-458	STKc_LIMK2
cd14113	270-521	STKc_Trio_C
cd14662	269-518	STKc_SnRK2
cd05615	276-468	STKc_cPKC_alpha
cd14174	274-522	STKc_Mnk1
cd14200	269-521	STKc_CaMKK1
cd05624	276-517	STKc_MRCK_beta
cd05582	340-500	STKc_RSK_N
cd14038	275-465	STKc_IKK_beta
cd05597	276-522	STKc_DMPK_like
cd14101	270-522	STKc_PIM2
cd07880	267-522	STKc_p38gamma
cd07849	268-521	STKc_ERK1_2_like
cd14048	271-458	STKc_EIF2AK3_PERK
cd07879	268-521	STKc_p38delta
cd05614	276-522	STKc_MSK2_N
cd07862	268-462	STKc_CDK6
cd14104	269-522	STKc_Titin
cd07839	269-520	STKc_CDK5
cd05039	266-517	PTKc_Csk_like
cd05613	276-522	STKc_MSK1_N
cd14151	266-516	STKc_B-Raf
cd14146	276-518	STKc_MLK4
cd14172	276-521	STKc_MAPKAPK3
cd14147	274-518	STKc_MLK3
cd05630	270-464	STKc_GRK6
cd05622	233-522	STKc_ROCK1
cd07877	269-521	STKc_p38alpha
cd05623	267-496	STKc_MRCK_alpha
cd14030	247-522	STKc_WNK1
cd14173	274-521	STKc_Mnk2
cd14092	271-533	STKc_MSK_C
cd14047	270-518	STKc_EIF2AK2_PKR
cd14158	275-463	STKc_IRAK4
cd14037	274-453	STKc_NAK_like
cd14164	270-464	STKc_TSSK6-like
cd05621	251-464	STKc_ROCK2
cd08227	276-525	PK_STRAD_alpha
cd13978	276-484	STKc_RIP
cd14148	276-517	STKc_MLK2
cd05059	267-516	PTKc_Tec_like
cd05608	273-522	STKc_GRK1
cd05617	320-469	STKc_aPKC_zeta
cd14149	275-525	STKc_C-Raf
cd14156	276-527	PKc_LIMK_like_unk
cd14150	273-509	STKc_A-Raf
cd14132	264-520	STKc_CK2_alpha
cd14108	270-518	STKc_SPEG_rpt1
cd05632	267-464	STKc_GRK5
cd13987	276-518	STKc_SBK1
cd07837	269-520	STKc_CdkB_plant
cd07853	276-521	STKc_NLK
cd14032	269-521	STKc_WNK2_like
cd07859	269-522	STKc_TDY_MAPK
cd06649	270-525	PKc_MEK2
cd07848	276-476	STKc_CDKL5
cd14225	269-521	PKc_DYRK4
cd14052	269-456	PTKc_Wee1_fungi
cd14109	274-521	PK_Unc-89_rpt1
cd05606	276-522	STKc_beta_ARK
cd14145	274-516	STKc_MLK1
cd14050	270-518	PKc_Myt1
cd07866	270-520	STKc_BUR1
pfam00786	74-128	PBD
cd05586	276-522	STKc_Sck1_like
cd05625	270-522	STKc_LATS1
cd05631	270-464	STKc_GRK4
cd05082	268-518	PTKc_Csk
cd07870	270-521	STKc_PFTAIRE2
cd14110	268-469	STKc_obscurin_rpt2
cd07876	261-498	STKc_JNK2
cd14170	276-521	STKc_MAPKAPK2
cd14049	268-459	STKc_EIF2AK1_HRI
cd05032	266-516	PTKc_InsR_like
cd05627	276-522	STKc_NDR2
cd14017	269-464	STKc_TTBK
cd07842	275-520	STKc_CDK8_like
cd07857	270-523	STKc_MPK1
cd13988	276-464	STKc_TBK1
cd07875	259-532	STKc_JNK1
cd13977	269-459	STKc_PDIK1L
cd05038	266-515	PTKc_Jak_rpt2
cd14016	269-428	STKc_CK1
cd05605	276-522	STKc_GRK4_like
cd05112	271-516	PTKc_Itk
cd07872	270-522	STKc_PCTAIRE2
cd14163	270-521	STKc_TSSK3-like
cd05618	325-500	STKc_aPKC_iota
cd14180	276-533	STKc_MSK2_C
cd05633	276-522	STKc_GRK3
cd07873	270-521	STKc_PCTAIRE1
cd14134	260-521	PKc_CLK
cd13992	293-513	PK_GC
cd07854	269-523	STKc_MAPK4_6
cd14053	274-458	STKc_ACVR2
cd05628	276-469	STKc_NDR1
cd05588	340-469	STKc_aPKC
cd07874	261-458	STKc_JNK3
cd14155	276-465	PKc_TESK
cd05053	266-517	PTKc_FGFR
cd07844	270-521	STKc_PCTAIRE_like
cd05108	269-525	PTKc_EGFR
cd14136	261-521	STKc_SRPK
cd05607	268-466	STKc_GRK7
cd07871	270-482	STKc_PCTAIRE3
cd05083	268-515	PTKc_Chk
cd14179	276-545	STKc_MSK1_C
cd14063	273-517	PK_KSR
cd14664	276-463	STK_BAK1_like
cd05057	269-525	PTKc_EGFR_like
cd14054	274-452	STKc_BMPR2_AMHR2
cd14100	276-521	STKc_PIM1
cd14056	274-464	STKc_TGFbR_I
cd05113	265-464	PTKc_Btk_Bmx
cd14223	276-509	STKc_GRK2
cd05148	266-479	PTKc_Srm_Brk
cd14205	273-457	PTKc_Jak2_rpt2
cd14011	277-521	PK_SCY1_like
cd14102	276-521	STKc_PIM3
cd05061	266-517	PTKc_InsR
cd05056	274-515	PTKc_FAK
cd13982	274-520	STKc_IRE1
cd13984	284-521	PK_NRBP1_like
cd07858	269-521	STKc_TEY_MAPK
cd05044	276-516	PTKc_c-ros
cd05081	276-457	PTKc_Jak3_rpt2
cd07869	270-482	STKc_PFTAIRE1
cd05080	268-466	PTKc_Tyk2_rpt2
cd05033	269-466	PTKc_EphR
cd05055	276-517	PTKc_PDGFR
cd14025	273-509	STKc_RIP4_like
cd05084	274-517	PTKc_Fes
cd14000	276-512	STKc_LRRK
cd13998	274-470	STKc_TGFbR-like
cd05114	271-517	PTKc_Tec_Rlk
cd14001	274-466	PKc_TOPK
cd14067	276-509	STKc_LRRK1
cd14224	269-521	PKc_DYRK2_3
cd14139	269-518	PTKc_Wee1b
cd13975	374-453	PKc_Dusty
cd05109	269-525	PTKc_HER2
cd05060	274-522	PTKc_Syk_like
cd14064	276-472	PKc_TNNI3K
cd05036	266-464	PTKc_ALK_LTK
cd05048	272-464	PTKc_Ror
cd05034	274-464	PTKc_Src_like
cd14142	274-457	STKc_ACVR1_ALK1
cd14159	276-475	STKc_IRAK1
cd14138	269-518	PTKc_Wee1a
cd14112	266-521	STKc_Unc-89_rpt2
cd05101	266-464	PTKc_FGFR2
cd05099	266-464	PTKc_FGFR4
cd14040	268-521	STKc_TLK1
cd05100	265-532	PTKc_FGFR3
cd05098	266-464	PTKc_FGFR1
cd14055	274-512	STKc_TGFbR2_like
cd14027	310-514	STKc_RIP1
cd14226	268-525	PKc_DYRK1
cd14152	274-516	STKc_KSR1
cd05085	274-515	PTKc_Fer
cd14212	270-521	PKc_YAK1
cd14051	274-518	PTKc_Wee1
cd05110	272-525	PTKc_HER4
cd14135	269-521	STKc_PRP4
cd05052	275-464	PTKc_Abl
cd14041	269-536	STKc_TLK2
cd05067	266-497	PTKc_Lck_Blk
cd05045	275-515	PTKc_RET
cd05103	375-518	PTKc_VEGFR2
cd05068	266-464	PTKc_Frk_like
cd05062	266-516	PTKc_IGF-1R
cd05079	267-458	PTKc_Jak1_rpt2
cd05102	375-517	PTKc_VEGFR3
cd05090	272-464	PTKc_Ror1
cd05040	274-509	PTKc_Ack_like
cd14207	375-517	PTKc_VEGFR1
cd14203	275-509	PTKc_Src_Fyn_like
cd05035	276-515	PTKc_TAM
cd05054	272-518	PTKc_VEGFR
cd14144	275-470	STKc_BMPR1
smart00285	75-110	PBD
cd05050	266-518	PTKc_Musk
cd05089	272-464	PTKc_Tie1
cd05116	275-509	PTKc_Syk
cd05107	375-516	PTKc_PDGFR_beta
cd05092	275-515	PTKc_TrkA
cd05071	275-464	PTKc_Src
cd05072	266-509	PTKc_Lyn
cd05047	276-464	PTKc_Tie
cd05111	272-525	PTK_HER3
cd05069	275-509	PTKc_Yes
cd05058	274-469	PTKc_Met_Ron
cd05097	266-521	PTKc_DDR_like
cd05074	266-517	PTKc_Tyro3
cd14140	339-458	STKc_ACVR2b
cd14216	261-521	STKc_SRPK1
cd05063	271-464	PTKc_EphR_A2
cd14153	274-517	PK_KSR2
cd14035	283-521	PK_MADML
cd05105	375-532	PTKc_PDGFR_alpha
cd07868	275-464	STKc_CDK8
cd05070	266-509	PTKc_Fyn
cd05095	266-464	PTKc_DDR2
cd14143	274-457	STKc_TGFbR1_ACVR1b_ACVR1c
cd14129	269-464	STKc_TTBK2
cd05073	266-497	PTKc_Hck
cd05075	276-527	PTKc_Axl
cd14220	275-457	STKc_BMPR1a
COG3642	274-409	Bud32
TIGR03724	343-409	arch_bud32
smart00220	270-521	S_TKc
pfam00069	270-521	Pkinase
COG0515	269-533	SPS1
smart00219	274-517	TyrKc
smart00221	274-517	STYKc
pfam07714	274-518	Pkinase_Tyr
PTZ00263	274-513	PTZ00263
PLN00034	186-526	PLN00034
PTZ00024	267-522	PTZ00024
PTZ00266	269-526	PTZ00266
PTZ00267	286-522	PTZ00267
PTZ00283	265-516	PTZ00283
PLN00009	269-522	PLN00009
PHA03212	263-461	PHA03212
PTZ00426	237-509	PTZ00426
PHA03390	315-523	pk1
PTZ00036	266-537	PTZ00036
PRK13184	269-467	pknD
TIGR03903	292-520	TOMM_kin_cyc
PHA03209	270-469	PHA03209
PHA03210	223-468	PHA03210
PHA03211	361-456	PHA03211
PHA03207	226-457	PHA03207
COG0478	342-408	RIO2

Ontology Information

HPRD ID	2045
Molecular Class	Serine/threonine kinase
Molecular Function	DNA repair protein (GO:0003685)
Biological Process	DNA repair (GO:0006281)

SNP Information

View SNP Geneview Report