CoReCG

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
22363125	2012	Cell line : - Source : The 174th Hospital of the Chinese PLA. Sample Type : CRC tumor No. of Sample : 16 Stage : Duke stage B,C,D	real time RT-PCR, microarray	Down-regulation	-	-

Gene Details

NC_000004.11 (55095264..55164412)
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Gene Type	protein coding
Gene Family	CD molecules, "Immunoglobulin superfamily / I-set domain containing"
Description	This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012]
Chromosome	4
Location	4q12
Start	55095264
End	55164412
Strand	+
Gene Sequence	Download Select all
Length	69149
OMIM ID	173490
HGNC ID	HGNC:8803
Unigene ID	Hs.74615
Ensembl ID	ENSG00000134853
PharmGKB ID	PA33147

mRNA Information

mRNA ID	NM_006206.4
Exon	join(1..319,29661..29721,31999..32316,34571..34831, 35823..35953,38193..38364,38456..38645,41537..41652, 43298..43424,44441..44634,45435..45529,45745..45877, 48292..48396,48800..48910,49266..49419,51220..51386, 56275..56390,56745..56867,58334..58445,59703..59802, 59913..60018,61217..61458,66029..69149)
mRNA Sequence	Download Select all
Length	6574

CDS Information

Location	332..3601
CDS Sequence	Download Select all
CCDS ID	CCDS3495.1

Protein Information

Protein ID	NP_006197.1
Protein Name	platelet-derived growth factor receptor, alpha polypeptide
Molecular Wt. (Da)	117118
Protein Sequence	Download Select all
Length	1089
Uniprot ID	Q13426
Ensembl Protein ID	ENSP00000282268

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
Y	Phosphorylation	720
Y	Phosphorylation	731
Y	Phosphorylation	742
S	Phosphorylation	767
Y	Phosphorylation	768
Y	Phosphorylation	993
Y	Phosphorylation	1018
Y	Phosphorylation	754
Y	Phosphorylation	762
Y	Phosphorylation	988
Y	Phosphorylation	849;-
S	Phosphorylation	851

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING) View

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
1398	CRK	1267	NP_058431.2	in vitro;in vivo	107 339 009 546 424
3690	ITGB3	1428	NP_000203.2	in vitro;in vivo	11953315
5154	PDGFA	1424	NP_002598.4	in vitro;in vivo	2544881
5159	PDGFRB	1423	NP_002600.1	in vitro;in vivo	2 542 288 752 312 220 000 000 000 000
5335	PLCG1	1398	NP_002651.2	in vitro;in vivo	7535778
6772	STAT1	2777	NP_009330.1	in vitro	9484840
6776	STAT5A	3301	NP_003143.2	in vitro	9484840
6777	STAT5B	5037	NP_036580.2	in vitro	9484840

Pathway Information

Pathway Name	Pathway ID
Calcium signaling pathway	hsa04020
Central carbon metabolism in cancer	hsa05230
Choline metabolism in cancer	hsa05231
Cytokine-cytokine receptor interaction	hsa04060
Endocytosis	hsa04144
Focal adhesion	hsa04510
Gap junction	hsa04540
Glioma	hsa05214
HTLV-I infection	hsa05166
MAPK signaling pathway	hsa04010
Melanoma	hsa05218
MicroRNAs in cancer	hsa05206
Pathways in cancer	hsa05200
Phospholipase D signaling pathway	hsa04072
PI3K-Akt signaling pathway	hsa04151
Prostate cancer	hsa05215
Rap1 signaling pathway	hsa04015
Ras signaling pathway	hsa04014
Regulation of actin cytoskeleton	hsa04810

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
cd05105	555-956	PTKc_PDGFR_alpha
cl21453	555-956	PKc_like superfamily
cd05859	313-413	Ig4_PDGFR-alpha
cl11960	313-413	Ig superfamily
cd05861	228-311	Ig1_PDGFR-alphabeta
cl11960	228-311	Ig superfamily
cd04972	415-497	Ig_TrkABC_d4
cl11960	415-497	Ig superfamily
cd05107	555-954	PTKc_PDGFR_beta
cd05055	555-954	PTKc_PDGFR
cd05106	552-954	PTKc_CSF-1R
cd05104	555-954	PTKc_Kit
cd05054	585-953	PTKc_VEGFR
cd05102	585-957	PTKc_VEGFR3
cd14207	585-953	PTKc_VEGFR1
cd05103	585-954	PTKc_VEGFR2
cd00192	597-951	PTKc
cd05053	580-953	PTKc_FGFR
cd05099	580-954	PTKc_FGFR4
cd05098	579-954	PTKc_FGFR1
cd05101	575-954	PTKc_FGFR2
cd05045	593-954	PTKc_RET
cd05100	580-969	PTKc_FGFR3
cd05034	597-951	PTKc_Src_like
cd05039	586-953	PTKc_Csk_like
cd05032	586-955	PTKc_InsR_like
cd05044	597-952	PTKc_c-ros
cd05036	587-953	PTKc_ALK_LTK
cd05050	587-951	PTKc_Musk
cd05041	599-948	PTKc_Fes_like
cd05068	586-943	PTKc_Frk_like
cd05049	587-952	PTKc_Trk
cd05047	598-947	PTKc_Tie
cd05048	587-943	PTKc_Ror
cd05148	586-952	PTKc_Srm_Brk
cd05089	598-967	PTKc_Tie1
cd05060	599-952	PTKc_Syk_like
cd05059	593-950	PTKc_Tec_like
cd05085	596-953	PTKc_Fer
cd05035	593-954	PTKc_TAM
cd05072	586-960	PTKc_Lyn
cd05056	586-954	PTKc_FAK
cd05052	586-953	PTKc_Abl
cd05051	587-943	PTKc_DDR
cd05038	588-954	PTKc_Jak_rpt2
cd13999	599-953	STKc_MAP3K-like
cd05088	598-946	PTKc_Tie2
cd05083	586-951	PTKc_Chk
cd05074	589-954	PTKc_Tyro3
cd05061	586-955	PTKc_InsR
cd05082	586-953	PTKc_Csk
cd05067	586-954	PTKc_Lck_Blk
cd05057	587-958	PTKc_EGFR_like
cd05092	590-940	PTKc_TrkA
cd05046	588-953	PTK_CCK4
cd05058	791-954	PTKc_Met_Ron
cd05033	597-953	PTKc_EphR
cd05073	586-953	PTKc_Hck
cd05075	593-954	PTKc_Axl
cd05084	596-943	PTKc_Fes
cd05097	587-943	PTKc_DDR_like
cd14204	590-956	PTKc_Mer
cd05113	589-946	PTKc_Btk_Bmx
cd05095	587-943	PTKc_DDR2
cd05062	586-946	PTKc_IGF-1R
cd05091	599-943	PTKc_Ror2
cd14203	599-952	PTKc_Src_Fyn_like
cd05112	591-946	PTKc_Itk
cd05096	587-943	PTKc_DDR1
cd05040	599-954	PTKc_Ack_like
cd05070	586-952	PTKc_Fyn
cd05043	781-946	PTK_Ryk
cd05071	586-952	PTKc_Src
cd05069	586-952	PTKc_Yes
cd05094	590-953	PTKc_TrkC
cd05093	590-953	PTKc_TrkB
cd04975	313-413	Ig4_SCFR_like
cd05063	597-954	PTKc_EphR_A2
cd00180	599-953	PKc
cd05114	593-954	PTKc_Tec_Rlk
cd05108	587-947	PTKc_EGFR
cd05090	587-943	PTKc_Ror1
cd05116	790-943	PTKc_Syk
cd05109	597-946	PTKc_HER2
cd05065	598-953	PTKc_EphR_B
cd05066	597-954	PTKc_EphR_A
cd05115	788-948	PTKc_Zap-70
cd05081	795-953	PTKc_Jak3_rpt2
cd05111	795-947	PTK_HER3
cd05079	597-954	PTKc_Jak1_rpt2
cd14205	786-953	PTKc_Jak2_rpt2
cd05110	597-947	PTKc_HER4
cd05064	587-954	PTKc_EphR_A10
cd05080	790-953	PTKc_Tyk2_rpt2
cd05742	228-308	Ig1_VEGFR_like
cd14058	599-954	STKc_TAK1
cd14061	795-953	STKc_MLK
cd06606	594-942	STKc_MAPKKK
cd14206	599-942	PTKc_Aatyk3
cd14059	599-946	STKc_MAP3K12_13
cd14060	782-953	STKc_MLTK
cd14146	795-953	STKc_MLK4
cd14145	795-943	STKc_MLK1
cd05042	599-942	PTKc_Aatyk
cd14147	795-953	STKc_MLK3
cd14062	599-951	STKc_Raf
cd14148	795-953	STKc_MLK2
cd05087	599-942	PTKc_Aatyk1
cd06627	595-942	STKc_Cdc7_like
cd13978	599-945	STKc_RIP
cd05122	595-942	PKc_STE
cd14063	796-953	PK_KSR
cd14007	595-951	STKc_Aurora
cd06628	797-942	STKc_Byr2_like
cd14151	586-953	STKc_B-Raf
cd08215	597-942	STKc_Nek
cd14150	599-953	STKc_A-Raf
cd14014	595-942	STKc_PknB_like
cd13992	796-943	PK_GC
cd14065	796-953	PKc_LIMK_like
cd14003	594-949	STKc_AMPK-like
cd14066	599-955	STKc_IRAK
cd05117	594-942	STKc_CAMK
cd05037	789-943	PTK_Jak_rpt1
cd05086	599-954	PTKc_Aatyk2
cd06614	801-942	STKc_PAK
cd06632	596-942	STKc_MEKK1_plant
cd14000	781-950	STKc_LRRK
cd06612	799-942	STKc_MST1_2
cd14221	796-954	STKc_LIMK1
cd08217	816-942	STKc_Nek2
cd06917	806-971	STKc_NAK1_like
cd05118	597-890	STKc_CMGC
cd13979	595-942	STKc_Mos
cd07829	774-899	STKc_CDK_like
cd14064	792-955	PKc_TNNI3K
cd13975	789-960	PKc_Dusty
cd14137	597-942	STKc_GSK3
cd06629	797-942	STKc_Bck1_like
cd14027	798-955	STKc_RIP1
cd06631	798-942	STKc_YSK4
cd14149	586-953	STKc_C-Raf
cd14155	785-954	PKc_TESK
cd07849	798-898	STKc_ERK1_2_like
cd05123	801-949	STKc_AGC
cd14008	777-949	STKc_LKB1_CaMKK
cd06611	799-942	STKc_SLK_like
cd06622	799-948	PKc_PBS2_like
cd08222	801-942	STKc_Nek11
cd14222	729-953	STKc_LIMK2
cd14154	796-953	STKc_LIMK
cd05619	793-940	STKc_nPKC_theta
cd14025	765-954	STKc_RIP4_like
cd08530	801-942	STKc_CNK2-like
cd06623	593-942	PKc_MAPKK_plant_like
cd14121	599-954	STKc_ULK3
cd08229	801-953	STKc_Nek7
cd14099	596-951	STKc_PLK
cd07834	798-899	STKc_MAPK
cd14002	775-895	STKc_STK36
cd14202	585-896	STKc_ULK1
cd13997	599-942	PKc_Wee1_like
cd07857	797-895	STKc_MPK1
cd05620	793-1018	STKc_nPKC_delta
cd06609	799-946	STKc_MST3_like
cd08228	801-953	STKc_Nek6
cd14156	802-953	PKc_LIMK_like_unk
cd14158	590-953	STKc_IRAK4
cd13993	597-940	STKc_Pat1_like
cd14009	599-895	STKc_ATG1_ULK_like
cd08223	801-946	STKc_Nek4
cd07833	605-942	STKc_CDKL
cd06608	589-946	STKc_myosinIII_N_like
cd07858	782-898	STKc_TEY_MAPK
cd07846	789-942	STKc_CDKL2_3
cd05592	805-940	STKc_nPKC_theta_like
cd06610	801-946	STKc_OSR1_SPAK
cd06621	774-897	PKc_Pek1_like
cd07863	739-889	STKc_CDK4
cd14001	794-952	PKc_TOPK
cd14186	797-943	STKc_PLK4
cd14120	599-887	STKc_ULK1_2-like
cd08219	795-942	STKc_Nek3
cd13996	597-950	STKc_EIF2AK
cd14080	592-885	STKc_TSSK-like
cd06619	802-942	PKc_MKK5
cd07854	752-898	STKc_MAPK4_6
cd08224	800-951	STKc_Nek6_7
cd05078	768-943	PTK_Jak2_rpt1
cd05589	802-940	STKc_PKN
cd06607	799-942	STKc_TAO
cd07862	791-889	STKc_CDK6
cd07859	798-898	STKc_TDY_MAPK
cd14044	791-943	PK_GC-C
cd06605	799-897	PKc_MAPKK
cd05077	801-943	PTK_Jak1_rpt1
cd07847	774-898	STKc_CDKL1_4
cd07838	799-891	STKc_CDK4_6_like
cd14131	775-954	PKc_Mps1
cd08220	782-949	STKc_Nek8
cd06613	801-942	STKc_MAP4K3_like
cd14012	787-942	PK_eIF2AK_GCN2_rpt1
cd06641	801-942	STKc_MST3
cd06620	768-896	PKc_Byr1_like
cd07845	782-898	STKc_CDK10
cd05616	798-940	STKc_cPKC_beta
cd13982	777-942	STKc_IRE1
cd14152	801-953	STKc_KSR1
cd07841	784-942	STKc_CDK7
cd06647	801-942	STKc_PAK_I
cd14077	797-951	STKc_Kin1_2
cd14047	800-953	STKc_EIF2AK2_PKR
cd06644	789-948	STKc_STK10
cd05570	798-940	STKc_PKC
cd14094	798-953	STKc_CASK
cd06633	790-976	STKc_TAO3
cd14079	798-940	STKc_AMPK_alpha
cd08225	795-942	STKc_Nek5
cd05581	596-942	STKc_PDK1
cd07852	799-898	STKc_MAPK15-like
cd07848	768-898	STKc_CDKL5
cd14198	777-942	STKc_DRAK2
cd05572	798-940	STKc_cGK
cd05579	798-949	STKc_MAST_like
cd06630	795-942	STKc_MEKK1
cd06640	801-942	STKc_MST4
cd06642	801-942	STKc_STK25
cd06654	804-942	STKc_PAK1
cd07840	800-898	STKc_CDK9_like
cd13989	785-888	STKc_IKK
cd05076	801-943	PTK_Tyk2_rpt1
cd14067	780-941	STKc_LRRK1
cd07830	594-898	STKc_MAK_like
cd14201	586-896	STKc_ULK2
cd14098	799-942	STKc_Rad53_Cds1
cd08528	812-947	STKc_Nek10
cd14042	624-946	PK_GC-A_B
cd06626	798-942	STKc_MEKK4
cd07843	777-942	STKc_CDC2L1
cd05578	802-898	STKc_Yank1
cd07839	753-902	STKc_CDK5
cd14039	777-929	STKc_IKK_alpha
cd08218	795-942	STKc_Nek1
cd14043	792-946	PK_GC-2D
cd14068	781-950	STKc_LRRK2
cd07856	798-898	STKc_Sty1_Hog1
cd14052	599-888	PTKc_Wee1_fungi
cd07853	798-890	STKc_NLK
cd14106	785-907	STKc_DRAK
cd14010	780-890	STKc_ULK4
cd14210	570-898	PKc_DYRK
cd07877	782-898	STKc_p38alpha
cd06616	799-900	PKc_MKK4
cd07873	744-953	STKc_PCTAIRE1
cd05582	801-898	STKc_RSK_N
cd06634	790-942	STKc_TAO2
cd06655	804-955	STKc_PAK2
cd14208	796-943	PTK_Jak3_rpt1
cd13987	800-906	STKc_SBK1
cd06638	805-946	STKc_myosinIIIA_N
cd05585	798-949	STKc_YPK1_like
cd14153	801-953	PK_KSR2
cd14187	798-946	STKc_PLK1
cd14209	801-924	STKc_PKA
cd06639	800-948	STKc_myosinIIIB_N
cd06617	799-948	PKc_MKK3_6
cd14119	801-942	STKc_LKB1
cd14197	777-942	STKc_DRAK1
cd07855	787-888	STKc_ERK5
cd07832	797-898	STKc_CCRK
cd06648	801-896	STKc_PAK_II
cd08221	794-942	STKc_Nek9
cd07831	797-942	STKc_MOK
cd07871	774-921	STKc_PCTAIRE3
cd13983	801-942	STKc_WNK
cd14086	800-942	STKc_CaMKII
cd06656	804-955	STKc_PAK3
cd14200	805-940	STKc_CaMKK1
cd06636	801-888	STKc_MAP4K4_6_N
cd14084	798-942	STKc_Chk2
cd05612	796-912	STKc_PRKX_like
cd05611	798-940	STKc_Rim15_like
cd08529	798-887	STKc_FA2-like
cd14116	595-941	STKc_Aurora-A
cd05860	313-409	Ig4_SCFR
cd14081	796-940	STKc_BRSK1_2
cd13994	781-951	STKc_HAL4_like
cd14045	797-950	PK_GC_unk
cd14026	800-945	STKc_RIP2
cd14162	592-886	STKc_TSSK4-like
cd07872	744-942	STKc_PCTAIRE2
cd14048	801-892	STKc_EIF2AK3_PERK
cd14076	594-896	STKc_Kin4
cd06625	798-942	STKc_MEKK3_like
cd07836	789-898	STKc_Pho85
cd14192	785-898	STKc_MLCK3
cd05580	801-940	STKc_PKA_like
cd14165	800-951	STKc_TSSK1_2-like
cd05595	801-896	STKc_PKB_beta
cd07851	800-911	STKc_p38
cd14049	800-948	STKc_EIF2AK1_HRI
cd06635	790-942	STKc_TAO1
cd05615	798-940	STKc_cPKC_alpha
cd14107	760-942	STKc_obscurin_rpt1
cd07866	745-889	STKc_BUR1
cd13998	790-940	STKc_TGFbR-like
cd14164	801-901	STKc_TSSK6-like
cd06659	802-896	STKc_PAK6
cd07864	797-890	STKc_CDK12
cd14104	777-898	STKc_Titin
cd14178	802-967	STKc_RSK3_C
cd14177	800-896	STKc_RSK4_C
cd06618	799-909	PKc_MKK7
cd05608	784-893	STKc_GRK1
cd14199	794-940	STKc_CaMKK2
cd06615	799-897	PKc_MEK
cd14011	800-941	PK_SCY1_like
cd14175	797-896	STKc_RSK1_C
cd14663	801-951	STKc_SnRK3
cd05571	806-960	STKc_PKB
cd14056	790-942	STKc_TGFbR_I
cd13995	793-942	STKc_MAP3K8
cd14180	808-977	STKc_MSK2_C
cd06637	786-888	STKc_TNIK
cd14054	802-943	STKc_BMPR2_AMHR2
cd14190	785-898	STKc_MLCK2
cd14133	781-898	PKc_DYRK_like
cd07878	782-898	STKc_p38beta
cd06653	798-890	STKc_MEKK3_like_u1
cd05630	798-896	STKc_GRK6
cd05587	801-898	STKc_cPKC
cd14004	801-942	STKc_PASK
cd14057	796-953	PK_ILK
cd14229	773-900	STKc_HIPK3
cd14082	801-894	STKc_PKD
cd14173	797-898	STKc_Mnk2
cd05590	798-905	STKc_nPKC_eta
cd14075	801-894	STKc_NIM1
cd14091	802-942	STKc_RSK_C
cd07860	774-899	STKc_CDK2_3
cd14078	798-946	STKc_MELK
cd14090	802-898	STKc_Mnk
cd00096	335-408	Ig
cd13977	797-886	STKc_PDIK1L
cd14111	794-896	STKc_SPEG_rpt2
cd14103	784-883	STKc_MLCK
cd07835	774-900	STKc_CDK1_CdkB_like
cd14050	792-888	PKc_Myt1
cd06624	798-948	STKc_ASK
cd07880	800-898	STKc_p38gamma
cd06650	802-897	PKc_MEK1
cd14038	785-887	STKc_IKK_beta
cd14006	797-942	STKc_MLCK-like
cd14176	800-896	STKc_RSK2_C
cd14072	595-942	STKc_MARK
cd07870	789-899	STKc_PFTAIRE2
cd06649	802-897	PKc_MEK2
cd07869	784-899	STKc_PFTAIRE1
cd05577	773-896	STKc_GRK
cd06643	801-888	STKc_SLK
cd14194	788-940	STKc_DAPK1
cd06646	801-891	STKc_MAP4K5
cd14185	773-940	STKc_DCKL3
cd05632	796-898	STKc_GRK5
cd14069	801-896	STKc_Chk1
cd13968	793-838	PKc_like
cd14196	788-907	STKc_DAPK2
cd05605	801-896	STKc_GRK4_like
cd14118	805-952	STKc_CAMKK
cd05631	805-896	STKc_GRK4
cd06658	788-896	STKc_PAK5
cd05584	788-898	STKc_p70S6K
cd14191	784-907	STKc_MLCK1
cd14105	788-913	STKc_DAPK
cd13985	780-951	STKc_GAK_like
cd14664	801-953	STK_BAK1_like
cd14665	798-940	STKc_SnRK2-3
cd06651	798-942	STKc_MEKK3
cd07844	774-899	STKc_PCTAIRE_like
cd14212	773-898	PKc_YAK1
cd05586	806-888	STKc_Sck1_like
cd14188	790-952	STKc_PLK2
cd07842	797-942	STKc_CDK8_like
cd06652	798-890	STKc_MEKK2
cd14167	794-940	STKc_CaMKI_alpha
cd14219	760-940	STKc_BMPR1b
cd14174	802-898	STKc_Mnk1
cd07861	797-888	STKc_CDK1_euk
cd14193	785-898	STKc_MLCK4
cd14073	785-944	STKc_NUAK
cd14220	795-940	STKc_BMPR1a
cd14096	801-940	STKc_RCK1-like
cd05613	794-940	STKc_MSK1_N
cd06645	790-891	STKc_MAP4K3
cd07875	800-898	STKc_JNK1
cd05603	798-895	STKc_SGK2
cd14053	790-942	STKc_ACVR2
cd05593	801-896	STKc_PKB_gamma
cd07850	798-898	STKc_JNK
cd14161	798-943	STKc_NUAK2
cd14113	790-942	STKc_Trio_C
cd14093	801-895	STKc_PhKG
cd05862	228-311	Ig1_VEGFR
cd05594	801-896	STKc_PKB_alpha
cd04976	334-410	Ig2_VEGFR
cd05602	798-895	STKc_SGK1
cd14108	769-907	STKc_SPEG_rpt1
cd07879	800-898	STKc_p38delta
cd14189	791-952	STKc_PLK3
cd13991	796-880	STKc_NIK
cd05604	798-951	STKc_SGK3
cd05607	789-896	STKc_GRK7
cd07837	797-900	STKc_CdkB_plant
cd14036	795-953	STKc_GAK
cd14089	799-944	STKc_MAPKAPK
cd07874	800-888	STKc_JNK3
cd14228	773-910	STKc_HIPK1
cd14195	788-907	STKc_DAPK3
cd05609	805-910	STKc_MAST
cd14020	773-890	STKc_KIS
cd14018	801-942	STKc_PINK1
cd14227	773-910	STKc_HIPK2
cd00096	231-293	Ig
cd14071	800-898	STKc_SIK
cd14109	798-940	PK_Unc-89_rpt1
cd14097	802-912	STKc_STK33
cd14170	777-940	STKc_MAPKAPK2
cd14005	801-951	STKc_PIM
cd06657	802-896	STKc_PAK4
cd14166	801-913	STKc_CaMKI_gamma
cd14037	787-948	STKc_NAK_like
cd07876	800-888	STKc_JNK2
cd14136	786-887	STKc_SRPK
cd14074	801-950	STKc_SNRK
cd14101	798-943	STKc_PIM2
cd14142	816-940	STKc_ACVR1_ALK1
cd07865	801-903	STKc_CDK9
cd05598	815-895	STKc_LATS
cd14179	815-896	STKc_MSK1_C
cd14169	800-940	STKc_CaMKI_beta
cd14144	760-940	STKc_BMPR1
cd14184	786-896	STKc_DCKL2
cd14143	790-940	STKc_TGFbR1_ACVR1b_ACVR1c
cd14100	743-943	STKc_PIM1
cd14225	781-898	PKc_DYRK4
cd14183	794-898	STKc_DCKL1
cd14211	773-910	STKc_HIPK
cd14092	801-896	STKc_MSK_C
cd08216	779-899	PK_STRAD
cd05575	801-927	STKc_SGK
cd05614	801-896	STKc_MSK2_N
cd14134	760-889	PKc_CLK
cd14223	794-896	STKc_GRK2
cd14055	766-940	STKc_TGFbR2_like
cd05583	806-896	STKc_MSK_N
cd14135	789-898	STKc_PRP4
cd13990	801-948	STKc_TLK
cd14662	798-940	STKc_SnRK2
cd14046	768-887	STKc_EIF2AK4_GCN2_rpt2
cd14141	723-942	STKc_ACVR2a
cd05617	798-896	STKc_aPKC_zeta
cd13988	780-896	STKc_TBK1
cd14114	794-940	STKc_Twitchin_like
cd05624	815-922	STKc_MRCK_beta
cd14182	806-940	STKc_PhKG1
cd14138	599-942	PTKc_Wee1a
cd14110	794-890	STKc_obscurin_rpt2
cd05606	801-896	STKc_beta_ARK
cd05601	815-943	STKc_CRIK
cd05864	337-410	Ig2_VEGFR-2
cd14088	801-914	STKc_CaMK_like
cd14172	802-940	STKc_MAPKAPK3
cd14070	719-942	STKc_HUNK
cd05748	337-409	Ig_Titin_like
cd05744	339-409	Ig_Myotilin_C_like
cd14112	801-942	STKc_Unc-89_rpt2
cd05724	340-398	Ig2_Robo
cd14159	790-890	STKc_IRAK1
cd05893	339-409	Ig_Palladin_C
cd14224	788-898	PKc_DYRK2_3
cd05591	801-895	STKc_nPKC_epsilon
cd14046	598-677	STKc_EIF2AK4_GCN2_rpt2
pfam07714	593-953	Pkinase_Tyr
smart00408	227-293	IGc2
smart00221	593-953	STYKc
smart00219	593-951	TyrKc
smart00220	595-943	S_TKc
pfam00069	593-943	Pkinase
COG0515	595-1043	SPS1
PTZ00283	801-942	PTZ00283
PLN00034	748-942	PLN00034
PTZ00036	786-897	PTZ00036
PTZ00263	801-940	PTZ00263
PTZ00267	800-898	PTZ00267
PRK13184	768-896	pknD
PHA03209	786-902	PHA03209
PTZ00024	801-895	PTZ00024
PHA02988	867-953	PHA02988
smart00409	223-293	IG
smart00410	223-293	IG_like
pfam07679	335-399	I-set
PHA03212	790-888	PHA03212
PLN00009	797-899	PLN00009
PTZ00426	798-896	PTZ00426
smart00409	335-409	IG
smart00410	335-409	IG_like
PTZ00266	792-955	PTZ00266
smart00408	339-399	IGc2
PHA03390	800-896	pk1
pfam07679	228-301	I-set

Ontology Information

HPRD ID	5457
Molecular Class	Receptor tyrosine kinase
Molecular Function	Receptor signaling complex scaffold activity (GO:0030159)
Biological Process	Cell communication (GO:0007154); Signal transduction (GO:0007165)

SNP Information

View SNP Geneview Report

Uniprot ID	DrugBank ID	Name	Type
P16234	DB00102	Becaplermin	BiotechDrug
P16234	DB00619	Imatinib	SmallMoleculeDrug
P16234	DB01268	Sunitinib	SmallMoleculeDrug
P16234	DB06589	Pazopanib	SmallMoleculeDrug
P16234	DB08896	Regorafenib	SmallMoleculeDrug
P16234	DB08901	Ponatinib	SmallMoleculeDrug