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General Information
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 20089989 | 2010 | Cell line : - Source : VU University Medical Center, Amsterdam, The Netherlands. Sample Type : CRC tumor and normal tissue No. of Sample : - Stage : - | Biochemical isolation to nano-LC-MS/MS analysis | Up-regulation | - | - |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | This gene encodes a protein which may be involved in bone development. Mutations in this gene are associated with susceptibility to osteoporosis. [provided by RefSeq, Nov 2009] | Chromosome | 5 |
| Location | 5q31.1 |
| Start | 132257658 |
| End | 132273454 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 15797 |
| OMIM ID | 603422 |
| HGNC ID | HGNC:16501 |
| Unigene ID | Hs.424312 |
| Ensembl ID | ENSG00000131435 |
| PharmGKB ID | - |
mRNA Information
| mRNA ID | NM_003687.3 |
|---|---|
| Exon | join(1..170,4952..5103,8807..8888,13258..13436, 13646..13809,14134..14251,14368..15797) | mRNA Sequence | Download Select all |
| Length | 2307 |
CDS Information
| Location | join(78..170,4952..5103,8807..8888,13258..13436, 13646..13809,14134..14251,14368..14572) |
|---|---|
| CDS Sequence | Download Select all |
| CCDS ID | CCDS4152.1 |
Protein Information
| Protein ID | NP_001124499.1 |
|---|---|
| Protein Name | PDZ and LIM domain 4 |
| Molecular Wt. (Da) | 25723 |
| Protein Sequence | Download Select all |
| Length | 246 |
| Uniprot ID | P20800 |
| Ensembl Protein ID | ENSP00000361668 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 112 |
| T | Phosphorylation | 114 |
| T | Phosphorylation | 115 |
| S | Phosphorylation | 116 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 7205 | TRIP6 | 4242 | NP_003293.2 | in vitro;yeast 2-hybrid | 10826496 |
| 11030 | RBPMS | 11870 | NP_001008712.1 | yeast 2-hybrid | 16189514 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd09451 | 255-307 | LIM_RIL |
| cl02475 | 255-307 | LIM superfamily |
| cd00992 | Feb-80 | PDZ_signaling |
| cl00117 | Feb-80 | PDZ superfamily |
| cd09360 | 255-306 | LIM_ALP_like |
| cd09450 | 255-307 | LIM_ALP |
| cd09448 | 255-306 | LIM_CLP36 |
| smart00228 | Jan-83 | PDZ |
| pfam00595 | Aug-80 | PDZ |
| pfam00412 | 255-305 | LIM |
| smart00132 | 255-305 | LIM |
| cd08368 | 255-306 | LIM |
| cd09449 | 255-306 | LIM_Mystique |
| cd09327 | 255-302 | LIM1_abLIM |
| cd00136 | 14-80 | PDZ |
| cd09391 | 255-295 | LIM1_Lrg1p_like |
| cd09352 | 255-303 | LIM1_Ajuba_like |
| cd09406 | 255-303 | LIM1_Leupaxin |
| cd00988 | 27-89 | PDZ_CTP_protease |
| cd09336 | 255-304 | LIM1_Paxillin_like |
| cd09351 | 255-303 | LIM1_LPP |
| cd09350 | 255-304 | LIM1_TRIP6 |
| cd09462 | 251-305 | LIM1_LIMK1 |
| cd09377 | 255-305 | LIM2_Lhx2_Lhx9 |
| cd09443 | 255-306 | LIM_Ltd-1 |
| cd09338 | 255-305 | LIM3_Paxillin_like |
| cd09379 | 255-305 | LIM2_AWH |
| cd09456 | 255-303 | LIM2_Enigma |
| cd09376 | 255-304 | LIM2_Lhx3_Lhx4 |
| cd09410 | 255-305 | LIM3_Leupaxin |
| cd09349 | 255-303 | LIM1_Zyxin |
| cd09414 | 255-305 | LIM1_LIMPETin |
| cd09359 | 255-305 | LIM_LASP_like |
| cd09361 | 255-305 | LIM1_Enigma_like |
| cd09340 | 255-305 | LIM1_Testin_like |
| cd09365 | 255-302 | LIM2_LIMK |
| cd09409 | 255-305 | LIM3_Paxillin |
| cd09413 | 271-305 | LIM1_Testin |
| cd09405 | 255-303 | LIM1_Paxillin |
| cd09362 | 255-303 | LIM2_Enigma_like |
| cd09331 | 255-303 | LIM1_PINCH |
| cd09447 | 255-305 | LIM_LASP |
| cd09328 | 255-285 | LIM2_abLIM |
| cd09466 | 252-293 | LIM1_Lhx3a |
| cd09348 | 254-307 | LIM4_FHL1 |
| cd09439 | 269-305 | LIM_Mical |
| cd09387 | 255-303 | LIM2_LMO4 |
| cd09457 | 255-304 | LIM2_ENH |
| cd09392 | 255-305 | LIM2_Lrg1p_like |
| cd09337 | 255-302 | LIM2_Paxillin_like |
| cd09407 | 255-302 | LIM2_Paxillin |
| cd09372 | 255-302 | LIM2_FBLP-1 |
| cd09355 | 255-284 | LIM2_Ajuba_like |
| cd09374 | 255-304 | LIM2_Isl |
| cd09339 | 255-304 | LIM4_Paxillin_like |
| cd09332 | 255-302 | LIM2_PINCH |
| cd09474 | 255-305 | LIM2_Lhx2 |
| cd09334 | 253-305 | LIM4_PINCH |
| cd09467 | 252-303 | LIM1_Lhx3b |
| cd09445 | 267-305 | LIM_Mical_like_2 |
| cd09358 | 272-305 | LIM_Mical_like |
| cd09475 | 255-305 | LIM2_Lhx9 |
| cd09363 | 267-306 | LIM3_Enigma_like |
| cd09346 | 255-302 | LIM3_FHL |
| cd09471 | 255-304 | LIM2_Isl2 |
| cd09461 | 255-306 | LIM3_Enigma_like_1 |
| cd09841 | 255-305 | LIM1_Prickle_3 |
| cd09484 | 256-305 | LIM1_Prickle_2 |
| cd09452 | 255-304 | LIM1_Enigma |
| cd09421 | 255-304 | LIM3_LIMPETin |
| cd00989 | 13-82 | PDZ_metalloprotease |
| cd09453 | 255-303 | LIM1_ENH |
| cd09431 | 255-302 | LIM3_Fhl2 |
| cd09438 | 255-304 | LIM3_Ajuba_like |
| cd09465 | 255-302 | LIM2_LIMK2 |
| cd09408 | 255-302 | LIM2_Leupaxin |
| cd09357 | 255-304 | LIM3_Zyxin_like |
| cd09375 | 255-289 | LIM2_Lhx1_Lhx5 |
| cd09368 | 255-303 | LIM1_Lhx3_Lhx4 |
| cd09483 | 255-305 | LIM1_Prickle_1 |
| cd09395 | 255-304 | LIM2_Rga |
| cd09383 | 255-305 | LIM2_Lhx7_Lhx8 |
| cd09415 | 255-305 | LIM1_Prickle |
| cd09397 | 255-305 | LIM1_UF1 |
| cd09330 | 255-285 | LIM4_abLIM |
| cd09396 | 255-301 | LIM_DA1 |
| cd09455 | 255-304 | LIM1_Enigma_like_1 |
| cd09364 | 255-305 | LIM1_LIMK |
| cd09393 | 255-302 | LIM3_Lrg1p_like |
| cd09430 | 255-302 | LIM5_LIMPETin |
| cd09446 | 255-305 | LIM_N_RAP |
| cd09429 | 255-302 | LIM3_FHL1 |
| cd09437 | 267-311 | LIM3_LPP |
| cd09354 | 255-288 | LIM2_LPP |
| cd09473 | 255-303 | LIM2_Lhx4 |
| cd09353 | 255-289 | LIM2_Zyxin |
| COG5338 | 110-211 | COG5338 |
| cl21487 | 110-211 | OM_channels superfamily |
| cd09440 | 274-305 | LIM1_SF3 |
| cd09463 | 255-305 | LIM1_LIMK2 |
| cd09464 | 255-302 | LIM2_LIMK1 |
| cd09343 | 270-302 | LIM1_FHL |
| cd09347 | 255-302 | LIM4_FHL |
| cd09400 | 255-302 | LIM_like_1 |
| cd09335 | 255-302 | LIM5_PINCH |
| cd09412 | 255-294 | LIM4_Leupaxin |
| cd09441 | 267-305 | LIM2_SF3 |
| cd09345 | 255-302 | LIM2_FHL |
| cd09356 | 255-284 | LIM2_TRIP6 |
| cd09432 | 255-302 | LIM6_LIMPETin |
| cd09411 | 255-304 | LIM4_Paxillin |
| cd00987 | 29-82 | PDZ_serine_protease |
| cd09458 | 274-306 | LIM3_Enigma |
| cd09459 | 274-306 | LIM3_ENH |
| TIGR03900 | Feb-98 | prc_long_Delta |
| PLN00049 | 34-87 | PLN00049 |
| COG0793 | 27-85 | CtpA |
| TIGR00225 | 27-71 | prc |
| PHA03269 | 105-217 | PHA03269 |
| COG3975 | 29-59 | COG3975 |
| PRK14086 | 82-214 | dnaA |
Ontology Information
| HPRD ID | 560 |
|---|---|
| Molecular Class | Unclassified |
| Molecular Function | Guanyl-nucleotide exchange factor activity (GO:0005085) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.