CoReCG

Search results:

General Information

Gene_Symbol	Gene_ID	Gene_Name	Chromosome	Alias
PGF	5228	placental growth factor	14	PLGF, PlGF-2, PlGF, SHGC-10760, D12S1900

Evidence
Gene
mRNA
CDS
Protein
PTM
Enzyme
PPi
Pathway
Structural
Domain
Ontology
SNP
Drug
External Links

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
19690493	0	Cell line : - Source : - Sample Type : - No. of Sample : - Stage : -	-	Up-regulation	-	Preoperative serum placenta growth factor levels were higher in patients with colorectal cancer, were negatively correlated with the serum sFlt-1, and could be used as a prognostic indicator for recurrence and survival for colorectal cancer.

Gene Details

Chromosome 14 - NC_000014.9 (74941830..74955764, complement)
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Gene Type	protein coding
Gene Family
Description	This gene encodes a growth factor found in placenta which is homologous to vascular endothelial growth factor. Alternatively spliced transcripts encoding different isoforms have been found for this gene.
Chromosome	14
Location	14q24.3
Start	74941830
End	74955764
Strand	-
Gene Sequence	>gi\|568815584:c74955764-74941830 Homo sapiens chromosome 14, GRCh38.p2 Primary Assembly CCTCGCACGCACTGCGGGCTCCGGCGCTGCGGGCTGGCCGGGCGCTGCGGGCTGACCGGGCGCTCCGGGA ACTCGGCTCGGGAACCTCGTCTGCGGTGGGCGGGGCCGGCCCGGAGCCCCGCCCCGGCTCAGTCCCTGAA ACCCAGGCGCGGACCGGCTGCAGTCTCAGAAGGGAGCTGCTGTCTGCGGAGGAAACTGCATCGACGGACG GCCGCCCAGCTACGGGAGGACCTGGAGTGGCACTGGGCGCCCGACGGACCATCCCCGGGACCCGCCTGCC CCTCGGCGCCCCGCCCCGCCGGGCCGCTCCCCGTCGGGTTCCCCAGCCACAGCCTTACCTACGGGCTCCT GACTCCGCAAGGCTTCCAGAAGATGCTCGAACCACCGGCCGGGGCCTCGGGGCAGCAGTGAGGGAGGCGT CCAGCCCCCCACTCAGCTCTTCTCCTCCTGTGCCAGGGGCTCCCCGGGGGATGAGCATGGTGGTTTTCCC TCGGAGCCCCCTGGCTCGGGACGTCTGAGAAGATGCCGGTCATGAGGCTGTTCCCTTGCTTCCTGCAGCT CCTGGCCGGGCTGGCGCTGCCTGCTGTGCCCCCCCAGGTAAGAGCTACCCCCACCTAGCCTGGCTCCCCA GACCTCCCCATCCCAGCACTGGAAGCATGGGACTCTGAAATCACAGACCCACTCCAGGGAGCAGCAACTC CAAGGATGTCCACACACTTCCTAAAGGCCAGGCTGGACTTCTTTCGTTTGGGAAGAGACCTCAGGCTGGC TGTCCCCCAGGTCCTGGGGGCTGTCTTGGTGGGGGCAGGGAAGCCACAGGGAGGGAGGGAGGGAGGGAGG TTTCCTGTCTGGCCCCTGGAGCCCTGGTGGCTTTGCTAAAAGCATCTGTCCACTAATCCCAGGCGGGTCC CTGGCCTTGTGGTCAGGGTCGAGGCCCCATGGCCAACCAGGCGTCCCCAGGACCTCTGACCTGGCCTGGT GGGGGTGGCGGAGGAGCCAGCTGAAGAAGCTGTTGGTGGGGAGGCTGGCCCTGCCCCCACCAGGGCTCAG GACTGAGCCGTGGGCTCCTGGGTGGGCTGGGGACGAGACAAGGGGTCTCGCTGTGCCTTTTCTCCTGGGT GGGTGGCCGGAGGTCCTGAGTGCAGGGCCTGGGGAAGTGAGCAGGGCCCTTTTCCCAGGAGCCGGGTGAG TCTGGCTGGGAGCCAGCTTGGGCAGTGAAATCCTGACAAAGCCAATGAACTGCCTTCCCACTGCGTTGTC CCACTGCCCTGGGAGTCCCCAGCCCCAGCCCAAGAGTAGGAGTGGGCTGGGCAGTCCCTGAGGAGTCCGA GCAGCCCAGCCACCCGCCTGCCTGCTGCAGGGCTGGCCAGAGGTGTAACGTTACCGGCTGCACCAGCTCA TGGCGCCACCCGCTCCAGCCCCTCAGCTCCCACCAGCTGATCACCTCCCCCTGGGCTCTGGCACCCAGCC AAGGCGGGCTGTGCAGGGCCCAGCAGGGTTGGCCTGGGGGCTGGGTAGAAGGCAGACCCGCAGGATTGGA AGATCTTTGGGATGCAGCAGGCCAAGGGTCTCCAAAAGCTTCTAGCCTCCCATCCTTTTCCAAATGAGGA AAACTGAGGCCAGAGAGGGGTGGGACCTAACCTACCCAGGGTCCAGTGAGTTTTTAGTGGTACTCAGGCT GCTCTGAGACAGGGCAGAGCATGTGCAGCAAGTGGGAAGGAACCCAGAGGGGCCCCTACCTTCTTGCCAT CACACTTGGCCCAAGAGTGCAGAGCTCCAAGGTACCCCCAGCTCACCTCTGCACTTTTCTGTCCATAGCA GTGGGCCTTGTCTGCTGGGAACGGCTCGTCAGAGGTGGAAGGTAAGCTGGCCAGGCTGGGGGTACGCATG CTCCCCAAGCCCCTCTCTTCCTTTCTCCCAAGCCCAGGTGTGGCATGAAGCGTGGGTGCAGGTTGATAAA AGCTGGGGAGAGCCTACAAGCTAGACATGCTGGGTGATGACTTTGGCAGGGCCTAAGAGATCCCCTCATG GTGACCCAGAGACTAGAGAGGTGTGGGCTGGAGTCACCAGCACACGGAGAGTGGGGCTGGGGCCAGTATA GCCAGGGTTCATCCAGCTGGCTCAGAGCCCTTCCCCAGCATGATTTAAGGGTATGGATGGGGTCTTGGAG GACAGGGTGGGGAGTGAGTGCCAGGGGCCAGAATGGGGGTCTGGGAGCTGAATGCAGTGGGCAGTCAAGA GGATCAGGAATGGGTGAGGGGCCCTCCCCAGCAGCCCAGCCCTGGTGGAACTGCCGGGATCTGACCATGC GTTTCCATTGATTATAAACAGACAGAACATAGTCGCGCCCTCCCTGGCCCCTCCACTCCCCGCCCTGGTT GCATCAAGAGGGAGTCTTCAAAGGGCAACGAGACGTTTGCCAAAGAGACATATGTACAGAAGGCAGGAGG CCCATGCCAGGCCCCCTACCTCGCTCCTCCCTCCCTGCCTCTCCAAGACGTGCAAAGTGGCCACACACCA CCGCTGAGGTTTCCCCTGCGCCATGGGAGAGTGGGCATGTAGGGACATGCACACGCACACGCGTGATAGC CATCTGCGTGCTGGGAACACCCTCTGCTGGGCTGCCTGCCTGGCAGCCCGCCTCTCCCGGGCCTGGCCAT ACTCTGACACCTAAGGCTTAGGCCCCTAGACCCCTGAGCAGGTAGAGGAGGTAGCTGCCCTTGACCTCAT GGATGCCTCCCTTGCTGTGCCTCTGGAACCAGCACAACATTATGCTCCTTGGGATTTGGGGAAGGACCCA TCCCCTACCTCCACACTATGCCCTTTTTGGTGCTTTTAGTGTAGGTCAGGCCACAGCTACCAAAGATGCC TTAGCCTCAGTTTTCTCATCTGTAAAATGGGAGCCTTGGCTACATGATGTCTATGGTTTCTTCTTTTTCC GAGATTGAAAAAGGGACTTGTCCTCTGACTCCAGGGAGGAGAAATGGGTGTACATATCACCCAGGATTTG AGGTGGGGAGGCCTGGAAGTGTAGATTCATTAGGTCAGCTCTCCTGTCACACTTATCAATCAGGGAGTCT GCAATCTGACCGGGAGAAGTACAACGAGCTTTGCACCCCAGCTCTCAAAATCTGAAAATGGCATCCCCAC CTGTTAACACCACAGCCAGAGACAGCATGGCCAGCCATGGGCATTGATTTTTACTATTACTATTCACGGT AACAATGTTAGGCATTTTCTGTCATTCTGTTTTGACCACAGGCTGTGAAGTAGGAAGGGGTTGTACTCCA TTTTTACAGATGCAGGCAGGCCCTGAGGCTCAGAGAGGCCCTGGGGGTCGCCCCAAGCCTCAGACACTCC TCATGGATCTGGCAGAACCAAGTGCTCCCAATAGCTCCGTGGCTGAGCGGGCATGAGCAGGGTGTCCCTT GTGGCAGGCTGTCTGTGTGCCCTGCCAGTGACCATGGAGAGGACACTTGTGGGCTTGGGCTGGTGGCCAG TGGCTCTGCCCAGCCCTGTGGCCCGTCTCCAGTGCCCTCCACAGAAACTTGCTCTCAGGATTAAGCATTT CTCTCCTGGGGTCTCCCCCATCCCAGGTGGTAGGTAGGCAGGTGGGAGGCTCACTCACAGGGCTGGCGAG AGAGCTGAGGGCACACTTGCAGCCTCAGGAGCAGCCCTGGGGACCACCCAGCCCTGGCAGTGCCTGAGGG GGCCCTGAGGGGGCCACAGCTTCCCGTTGCTCTCACCTCCACCCCCTCCCGGAGCAGGTCTGGGGCCAGC GGAAGTGCTCTCGGGGACAGCTGAGCAGAGCTCTTTCCTGAGGGACACAGCCCACATCTGGGAGCGGTCA CTGTACTCCCTCAGCCCGGCCCCTCACCCAGCCCCTTTTGTTTCTCCCACACACCCATAGCGGGGCCTTC AGGGATGAATTGCCCTTTCCTGGTGGCTGCCAGGTAAACCAGGCTCCAGCCCACCTCCTTCTCAGCCCTC CCCCAACACAGTTCGGCCACAGGGCTGGGAAAGTGGCAGATTCCAGGGTTTCAGGGACCCGGAACCTGCA TGGTGGGATGTGGGGTGAGGAAAGGAAATCCCTTCTTCTGCTGCCGAGGCCCAGCCAGTTCTGCCAAAGG TGGCCATGGCCCCGCAGCCCAGCTGGGTGGGTGTCTGTTTGCAGGATGGAGGGGGCTGGGGTGCCCCTTC TCTGCTGCTGTCCCCTCGCTGACGGCTGGTCCCAGGGCAGGAACCTGAGTCTTCTGTGGTGCTTTGGCAG CTCATTATTCCTCTGCTGTTATTTATGTTTTCCAAGGTGGAGATTAAACGTTCAGAGTCACGTAGTGCTC ATGAAGATTTTAAACTAAACACACAGCTCAAGGAGCTGGTGATAGGGAGGTGCTCTCTGACCCAGGATTG CAAAGGCAGGCTTCCCTGCACTTTGGGCGCCTTTGGGGAGAGAGGCCTTGTTTCCCACTGGGTTCCGGGG CAGTATCCAGTGGCGCGGAGTGGTAGAGTCAGAGGAGGCCTATGGATTCCCCCCACCACCAGCCCCTAGG CCCTAGTGCCCTCTAAGCAGAGCACGGCAGAATGGAGCAGAATGGAGCAGCAAACAAGCAGATAACACTG TTTATTGCCTCTATGACTGCCTAGCCAGCTCCACATGGACACACCGCCTCTGGGTATTTTCCACCAGTTT GCAGCCTTTCCCGAGGGCCTCTGCTAGGACTGAAGTTTATTTTTCTTCCGAGATTACCAGGAGGCTCATG TCCTCATAGGCTCAGTGGAATGGACTTTGGCCCCTTCTGCCTCCTAGGCAGAGGCATGGAAGAAATGAGG GGTTGCTGGGAGAGGCCATTGTTCCATGGCAGAGGCTGCAGGACCCCCAGCTCCCCATTCTTCCCCACTA GCTGAGGATGACCATCAGATGCAGAGCAGGATGACCCAGGCCTGGGGGTGTTTCTCTGTCCATGGTCTCT GGGCTGGGCTGGGTTGCAGGCACTGATTCACAGGCGGTTGGTCAGAGAGGGAAAGACCTTAGCAACCATT TATTCCCAACCTTCTTTTTTCCCACCTGAGGAAACTGATCTATCCAGAAAGGTTAAGTGATCTCCCCAAG GTCACATAGCCAGTGTAGGGCCAGGACTGGAAGCCAGGTGTCTGACTCTGGCCACTCTCCCTGTGAGCCT CTATTTGGGGCCTGGTCCTAGGCCTTCCCCCGAAAGAGCAGCATCTTTTGAGGGATTCCAGATCAGCCCC CAAAAGATCCCATTCACGATCGCCAGGACATCGTGAGGTCAGGGATGACCCGGATGATCCTCAGTGAAAT GTCATCTAATCAACCAGGAGTGACTTAGCCTGTGTTTACGGGTACGTCCATCTCTGCCCTCATGGAGCCT CGAGTTGGTTGTAAAGGAGATAAGAGCAAGCAGTGCCGGAGATAAGGCAACCCCTTGAGGCCAGAGGCCA AGCAGTGCTCAAGGGAGGCTCATCTGTGTGCACTGGAATTGCTGGGGAAGTCTTCAAAGAGGAGGTGGGG AGGCAGGTCGTGGAAAATGGCGGGTGGACTTTATTTGGATAGAAATGAGAGGAGGGGGAAGAAGAGCAGC TGTACGGGCTGCAGAGTGCACAAGCCAGAGCTGGGAGTGAATGTGGTGCTGCCGTGGCTCAGTGTGAGCG CTGGTTGGACTCAGTGGAGAGGAGGGTCGGGCCACATTGCTGGATGTGGTCTTGGTTGCCAGGCAGAGGA GCTGGCACAGAGTGGGGCAGGAAATGAGGGAGCCGTGGAAGGTGTTTGAGCAGAGGAATAAGGGAAGGCC AACCCTCCCTGCATGACTCCAGGAATGACTGTTTTCTGCAAGTTCTCCAAGTTGGAGGAAGCACCGGGTC AGGCTTGAGAAAGATCCAGAGGGCCTGGGTAGCTGCCGGGGCTACAATCCTCAAAGCTCCAGGGAGCCAA GGCAGACGTGGGTGCCTGAGTTGAGGACAGAGCAAAGCTTGGGACCCTGAGAGATTCTGTTCCATGGGGA TTTCCATCCAGCAGATGAGCTAAGGGGCCCGCAGGCATTTCGGAGGGATCACATTAGGAGTTCAGAGTTG AGGGAGCTCGGATGGGGCTGGGGGCTGAACCTGGAAGGCCAGCAGGGCCTTGGGAGCCAGGTTTAGGGCT TCAAGGGGCAGGTCTCTGCTGGCCTGACCCAGCCCCCTTGCTTCCTCGCAGTGGTACCCTTCCAGGAAGT GTGGGGCCGCAGCTACTGCCGGGCGCTGGAGAGGCTGGTGGACGTCGTGTCCGAGTACCCCAGCGAGGTG GAGCACATGTTCAGCCCATCCTGTGTCTCCCTGCTGCGCTGCACCGGCTGCTGCGGCGATGAGAATCTGC ACTGTGTGCCGGTGGAGACGGCCAATGTCACCATGCAGGTAGGTCCATACCCTGCCCAGGGGGCCACCGA ATCTGCCCACTAGAAGGTACCTGGAGAGGGAAGAAGATAGGCCCAGGTCCCAGGGCTGGAGCCTGACTCC CAGGCCAGTGCTCCTACCACCCCAGCCCAGGGCCTCTTCTTCCTAAGCCCTCCGATGGCTCTGAGCCCAC TCATCTCCACCCCCACCAGCATTCTCAGCCTCACGCTGAGTCCTATCCCAAGACTCAGGGTGTCTAGTTA AAGCTGGAAAGAAATCTGCTTGTATAAAGTCCCTGTTGACACCAGGAGCATTTGGTCCCTTTTCAAGCAA GTGCAGCTTACATGTCACACACGCAGTGGTTTACTGAGCACTTACTGAGTAATGCCAAGCACTGTCCTAG GCGTGCCACAAGTGGTGTGTCATTCAATCCTTCAAGGCTGGTGTCATTCCCATTTCACGGATGGGGAACT CAAGGTTCAGAGATGTTATTTCACTTGTTCAGCAGGTAAAAGAGTCAAGATCTGAACACGGGTCTCTCTG ACTCCAGAACATGAGCCCCCTTCCTGTGCTATTGCTGTGCTAGTGCTCCCGGGCAGGGAGGGACAGGGGC CTCCCTCAGATCCCCATGCAGCTGAGAGAGCTGTTTGCCCCACGTTCAGAGTGGAGTGAGGGCCTGTAGT CCACAGGCTAGCAGGAAACAGAGTCGGGTTCTCCTTACAAGGAGAGAGAGAAGAGTGCCGGAAACTCGTG GGCCACTCCCCAATCCAGGCATCAACTCTTTCTTCCTTCAGCTCCTAAAGATCCGTTCTGGGGACCGGCC CTCCTACGTGGAGCTGACGTTCTCTCAGCACGTTCGCTGCGAATGCCGGTAGGTCTCCGGGGTCGGGTGG GTAGCAAGGAAAGGCCCCCGTCCTCTTGGCAGCCTCAGCAAAGATGGGTCCCAGGGCAGAGGCAAAGGCT GCCCATCCCCGCTGCGGGCTGAACTTTTTTCCAGACTGAGGGAGACCAAGAGGGCAGGACCAGGGGTGGC TACCATTCATTTTGTCCCCCCACCAGCCAGTTTTGCCAAGGGAGCTGGTCCCAGCAGCTGGGGTACAGCT GTTGAGATACTGCAAGGGAAGAGAGAGGGTGGGTCCCTCCCAGCCTCGCAGGGGTTCGGTGCGTGTCGTT CCCCTTCTCTGGGATGGGAGGCAGCTGCCACGGGCCTCTGAAAGAGGTGCCTGGAGGCAAAGACATTGCA AGTCTGAACTTCGTTCTGGGGCAAGCTGTGTGCCCACAGGAGCGGGCAAACGGGGCTGAGAAGCAGCAAG AAGGACAAGCTCGGGTAGGAGAAAAGGGGCAGAAGAAGAGTGACACTGTGGCTTCCTTGATGTTGCAGCA CCCCTCTACGGCCCCTCCCAATCCACAGAGCCTCTGACCAGCACCAGTCTTGCTGCCTGTGCTGGGGGCA CTTGGAACATTGGTTAGCAGGAGCAACAGGCCTGGCACTGCCAGCTAGGTTCAGGGAAGAGAGAAATGGG CTGAGCTGCTGCTCCTGGTACTACTGGGCCATGGATGAAGGCACCAGACTAGAAGTCCAGAGCCCTAGCC AGGGGCGGCAGGAGGGAAGACTACCACTTATTGTGTACCTATTCTGTGCCTAGCCCCGCAGGAGGCACTT GAATGTTTCTCATTTAGTCACATACATTTATTGAGCACCTACCACATGCCAGGCATTGTCCTGATGGGAT GCAGTGGTGAGCAAGGTTCCTGCTCTCATAACAACCCTGGGAGGTAGGCCCTATTGTCATCCCCATTTTA CAGATGAGAAAATCAAGGCTCAATACAGTTTCATGATTTATCACAGCTAGTGAGTGTGGGAGGAGGGATT CTGGGCCCTGACCTAACTCGTAAGCCTTCGTTTTTCAGGCTACCTTTCATGGCCATGACCACTTTTCTAA TAGCCCCCAGGCTTAGCCTTGCCTCCTGGGCAGGGCTATGGCTGCCCCTTTTGTTGGAGTGTTGGAGACC CTGCCTCAACTTGTTTCCACCCATCCCTCCAAGCCAGAGCTTAGCCATATAACAAGAGCTCGGTAATGAA CCCTCCTGGGTGCAATGCTGGGTGGTGACCCAGAGTCACCTTCTCCATCCCCTTTGCCCTGACAGCCACT CTTTTGGGGCAGGCAGATGAAGAGACTGAGGTTCCAAGAGTGTCTGTCACTTGCCCAATATGGAGAGGTA CAACCAGACAGTCCCAAGAGGCCCTGGTACCTTGCCCTGGCTCCCAAGGGAGGAACCAGCTGAGGGTAGC ATGTCCTGGCCCCAAAGCTGACTGCTACCATGCTGTCCCATGTCTCTACCCACTGTTCCCAGTGAAGACT GAGGCCCTATCCCCTGCCAGGGGCCAGGCAACAGGGACACCTTTCTTCTTGCTTCTGGGCCAACAGCCAC AGCCCTGGGAGGCAGAGCCCAGACATGCCTGGTGACTTCAGGGCTGATGCTCCCTCCTTCCTCCCACCCC GTCGCTCACTCCCCATGTTGTTCCGGATGGAGTGGGGCTGTGCCCTGACAGGCAGCCAGTCCGCTGTCTG GCCATCATCTCCTGTCCCTGAGGAAATTCCCAGAATGCACCCTGGAAGGAACGGAAAAAAGCAGCAAAGA AAGTGAGAAAGAAAAAGCAACAGAGAACAGACAGAAACAACCAAATTTGATGCCAAGAGGCTGAGAAGTG CAGAAGCGGGTGGCAGGGGTCCCCAGGAGGTTGATTTGTCCCTCTCGTGGTGGGGTCACCAGAGCCTGGA GTGGGAGTGAAGCCTTGAGGCTCTGGCCACCTCTCCCTTGCCAACTCCATGCTACCCCCTAGTGGCCTCA GTGTCAGCTGCAGGACCAGGACTGGGGATGTCGGAGGGGACCTGTCCGGGCGGCAGGGAGCCCCACTTAT TGCTTTCCTAACGTTCCTCTGCCCCTCTCTCTGTCTGTTTCCCTAGGCCTCTGCGGGAGAAGATGAAGCC GGAAAGGTAAGTGGTTTGGCTGGGGCTCGGGGCTATTCTCGGGCCTGCCAGCCTCTGTCCTAGCATGGGG TTCCCCAGCCACCTTGTCCTGACGCTTGGCTTATTGCAGGAGGAGACCCAAGGGCAGGGGGAAGAGGAGG AGAGAGAAGCAGAGACCCACAGACTGCCACCTGTGAGTGTGCGGGGTCCCAGGGATGGCGAGGAGGCTGG GCCCGAGGGGAGCCCCGCCTTGCCGCCAGGGTTAGGTTGGGGAGGGGGAGAGGCAGGACTGAGGCCAGTC TTGGGGGCAGAACAGGGAGCTGCACCTCCTCAAGACTCTAGGGCCCAGGAAGCATCAGTGGACCTTGGTT TTTGTCCCGGCTTAGCCCTAGGTTTCCATTGACCTTCAACAAATCATTTCACCTTTGTCAGCCTAGCTTT TCTCTGTGTAGAATGAGGGGCAGGAGGTCCAGCAAACATTCAGTCACTCTACAAACATTTACTGAGCACT TACTGTGTGTCAGGTACATCTGTGAGCAAACAAACAGGATTCCTGCACATTAGTGTTTACCTTTTAGTGA TTAAAAGTCTGTCATCAGCTGAGACGTTATCTGGGGCCACTTCCTAGTAGCCCCGGGGAACATGTGCCCC TCGCCACTGTCTCCCAGGAGTATTTTTGCCTGTGGGTCCCCTTGCTGCTTCTAACCCACTTCGTACCTTG TGGGCAGCAGAATGGAGCCCCAGGCCTGAGTGTGGCTGGGAGAGAAGGATGAGAGGAGGGAAAACCCAAA TCTGTGAGAGTAAATAGAAAAAATAAAATATTTCACGTGCACAGTCAATCAGTCACTGAAGAGAGGTGGC TCTCCTTCAGGGGCTAAGCCTCCCCCACGCACGTGACTCCAGGAAGTCATTTCGTGCTATGGAGTGGAGT TGACCCAAGCCCTGACCCCATGAGCCCCACTCCATGAAGACAGGGATCCTGGGGACTGCGCCCCCTAGGG GTTTATGCTCTCATCTCTTTTCTGGGCCCGCGCGGCAATTTGGGAAACAAGCTGGCAGGGAAGTCCATCC AGGCCCGAGTTACCCGCCGGCAGCCGGAGGCAGAAAGTGTCCCGTGGCTCCTGTTCCCAAGGCAGCAGTC TTCAGACATTTCACTCGGGAATCTCCTGAAAGAATTTCAAAAGTGGCCGGGCGCAGTGGCTAACACCTGT AATCCCAGCACTTTGGGAGGCCGAAGTGGGTAGATCACTTGAGGTCAGAAGTTCGAGGCCAGCCTGACCA ACACGGTGAAACCACATCTCTACTAAAAATACAAAATTAGCTGGGCGTGTTGGTGCATGCCTGTAATCTC AGCTACTTGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAGGCGGAGGTTGCAGTGAGCCGAGATC ACGCCACTGCACTCCAGCCTGGGTGACAGAGCAAGACTCCGTCTCAAAAAAAAAAAAAAAAAGAATTCCA AAAGCCCATGTGCTCCCTTGCCCATTCTTAAGTTGACATTGAACATTTTCATCAGAATTATAAGTCAAGC CAGGCTCAGTACCTCATGCCTGTAATTCTAGCACTTTGGGAGGCCGAGGCGAGTGGATCGCTTGAGGCCA GGAGTTCAAGCCTAGCCGGGGCAACATGGTGAAACCTCGTCTCTACAAAAAAAATACAAAAACTAGCTGG ACGTGGTGCCATGTGCCTATAGTCCCAACTACTCAGGAGGCTGAGGTGGAATGATCACCTGAGCCTGGGA GGTCAAGGCTGCAGTGAGCCGAGATAGATCCACTGCACCTCAGCCTGGGTGACAGAGTAAGAACCTGTCT CAAAAAAAAAAAAGTATAAGTCATTACAAAGGATATAATTTCTGGCATATTATTAATATTTTAATACAAA GCTATTGTAGAACACTCTCCAGGTGTATCCTATTAAATACGCCATTTTAATGTTATACTCACCATCATCC ACTTTTAAGAAAATGAACAAGCAGGCCAGGCGCGGTGGCTCACACCTGTAATCCCAGCACTTTTGGAGGC CAAGGCGGGCGGATCGCAAGGTTAGGAGATCGAGACCATCCTGGCTAACATGGTGAAACCCCATCTGTAC TAAAAATACAAAAAATTAGCCGGGTGTGGTGGTGGGTGCCTATAGTCCCAGCTACTCGGGAGGCTGAGGC AGGAGAATGGCATGAACCCGGGAGGCGGAACTTGCAGTGAGCCGAGATCACGCCACTGCACTCCAGCCTG GGACAGAGCAAGACTCCGTCTCAAAAAAAAAAAAAGAAAATTAACAAGCAAAAAAAAAAAAAATACAGGA ACACTTCCTTTCATAATTATATATTTACATTGTTTCTTTTTTCCTGGAACTTGTATTTCCATTTCACTCC CCACCCCCAAGAATTTCAGCCTAGTGTAACAGTACTTTTAATTTTCAGAAGTCTTTTATTGATTACCTTG TCATATTTATCTGCCACAAAAAAATGATATATGAGTTTGAATTATTTTAAATTTCCTGTGAGCATAAACC TAAATTAAATTTTCTCCTGGAATAAATTATCAAAATAATTCTTAGTAGCACCATTTGGTCAAAACAGCAC AAATACTTCCTATTTTAATAGATGTTCAACATAAAAATACAATCAATTTGATTGGGAATGCATCTCAATG AGATGGATGTGGCTACCTCGTTTCAATTAGTGAATGAATCCATTAATGAATGTTACTTCCTGCCAGACTG AGACAGGATTCTGCATTAATTTAATTCCTGTTTATCATTTTTTTATTGATGAGAAGGTTGAGAAACCATG TTCACATAAATAAGTAAATGAGACTAGATGTCACTCAATTACTTGAACTCCTTCCTTCCAAGTTATTTGC CAGAAATCTCAAGGTGCTCTGCTAAGAACAAATTACTTCTCATGATATCCTGGCTGACAATTTGGTTAAG CTGTTCTTCAGTTTTGTTGAAAGCCTTGGTTACCCAGTCATTAGCCATATTTTCTTTCTCAAGACCTACA TCAATATCTCAAATTGTTCTTTTTTTCATGTCCTCAGAATACTTTTACCTGGCAGCAAAGCACTTTATGA GGATTTAGAATGAGCAAGATGTGTTGTGGCCAGAGAAGCAGATCTCAGCCACTGCCTCACAAAAATAATT TTAAGGCAATGTAGACCTGGAGGCTGAAAATGGATTTCTTTAAAACCGTCAGTACTCAGGCCTCACGTGC GTCTAGCGGTACTCCCCTGTTTGGAGACTGCTGTCTTAGGGTAATCAGAGGCATGATTGCATGGAGTGTG ATTAGGTTCAAATGTGGCTCTGTCACCGACTGGCCGTGTGACCACAGGCAAGCTTCTTCACCTCTCTGGG CCTCAGTTTCCTAATCTTCACAAGAATAATCAGGGTGCCTTCCTCATGGAAGGTTGTTGAGGGTTAAGAA GACAGTGCTTGGCACAGGGCTGGGCACATGGGTAAGTGTTTGGTGAAGGGTAGCTCCCAGCTTCTCCTCA GCTTGAAGCAAGCAGGGACCCAGGAGCACTGCGCCCTCCCCATGCTCCCTGCCCAAGCTCCTCCTCTGGG CCTGCCCCCTCCTCCATAGGAGGAGACCGCACCCTCCACAGTGTGCTGATACCCGCCCCGTCTGTGCTTG GTCTCTGGCAGGTGCGGCGATGCTGTTCCCCGGAGGTAACCCACCCCTTGGAGGAGAGAGACCCCGCACC CGGCTCGTGTATTTATTACCGTCACACTCTTCAGTGACTCCTGCTGGTACCTGCCCTCTATTTATTAGCC AACTGTTTCCCTGCTGAATGCCTCGCTCCCTTCAAGACGAGGGGCAGGGAAGGACAGGACCCTCAGGAAT TCAGTGCCTTCAACAACGTGAGAGAAAGAGAGAAGCCAGCCACAGACCCCTGGGAGCTTCCGCTTTGAAA GAAGCAAGACACGTGGCCTCGTGAGGGGCAAGCTAGGCCCCAGAGGCCCTGGAGGTCTCCAGGGGCCTGC AGAAGGAAAGAAGGGGGCCCTGCTACCTGTTCTTGGGCCTCAGGCTCTGCACAGACAAGCAGCCCTTGCT TTCGGAGCTCCTGTCCAAAGTAGGGATGCGGATCCTGCTGGGGCCGCCACGGCCTGGCTGGTGGGAAGGC CGGCAGCGGGCGGAGGGGATCCAGCCACTTCCCCCTCTTCTTCTGAAGATCAGAACATTCAGCTCTGGAG AACAGTGGTTGCCTGGGGGCTTTTGCCACTCCTTGTCCCCCGTGATCTCCCCTCACACTTTGCCATTTGC TTGTACTGGGACATTGTTCTTTCCGGCCAAGGTGCCACCACCCTGCCCCCCCTAAGAGACACATACAGAG TGGGCCCCGGGCTGGAGAAAGAGCTGCCTGGATGAGAAACAGCTCAGCCAGTGGGGATGAGGTCACCAGG GGAGGAGCCTGTGCGTCCCAGCTGAAGGCAGTGGCAGGGGAGCAGGTTCCCCAAGGGCCCTGGCACCCCC ACAAGCTGTCCCTGCAGGGCCATCTGACTGCCAAGCCAGATTCTCTTGAATAAAGTATTCTAGTGTGGAA ACGCT Download Select all
Length	13935
OMIM ID	601121
HGNC ID	HGNC:8893
Unigene ID	Hs.252820
Ensembl ID	ENSG00000119630
PharmGKB ID	-

mRNA Information

mRNA ID	NM_001293643.1
Exon	join(1..597,1822..1861,6212..6408,7182..7258,9357..9386, 9490..9552,13032..13935)
mRNA Sequence	>5228 CCTCGCACGCACTGCGGGCTCCGGCGCTGCGGGCTGGCCGGGCGCTGCGGGCTGACCGGGCGCT CCGGGAACTCGGCTCGGGAACCTCGTCTGCGGTGGGCGGGGCCGGCCCGGAGCCCCGCCCCGGC TCAGTCCCTGAAACCCAGGCGCGGACCGGCTGCAGTCTCAGAAGGGAGCTGCTGTCTGCGGAGG AAACTGCATCGACGGACGGCCGCCCAGCTACGGGAGGACCTGGAGTGGCACTGGGCGCCCGACG GACCATCCCCGGGACCCGCCTGCCCCTCGGCGCCCCGCCCCGCCGGGCCGCTCCCCGTCGGGTT CCCCAGCCACAGCCTTACCTACGGGCTCCTGACTCCGCAAGGCTTCCAGAAGATGCTCGAACCA CCGGCCGGGGCCTCGGGGCAGCAGTGAGGGAGGCGTCCAGCCCCCCACTCAGCTCTTCTCCTCC TGTGCCAGGGGCTCCCCGGGGGATGAGCATGGTGGTTTTCCCTCGGAGCCCCCTGGCTCGGGAC GTCTGAGAAGATGCCGGTCATGAGGCTGTTCCCTTGCTTCCTGCAGCTCCTGGCCGGGCTGGCG CTGCCTGCTGTGCCCCCCCAGCAGTGGGCCTTGTCTGCTGGGAACGGCTCGTCAGAGGTGGAAG TGGTACCCTTCCAGGAAGTGTGGGGCCGCAGCTACTGCCGGGCGCTGGAGAGGCTGGTGGACGT CGTGTCCGAGTACCCCAGCGAGGTGGAGCACATGTTCAGCCCATCCTGTGTCTCCCTGCTGCGC TGCACCGGCTGCTGCGGCGATGAGAATCTGCACTGTGTGCCGGTGGAGACGGCCAATGTCACCA TGCAGCTCCTAAAGATCCGTTCTGGGGACCGGCCCTCCTACGTGGAGCTGACGTTCTCTCAGCA CGTTCGCTGCGAATGCCGGCCTCTGCGGGAGAAGATGAAGCCGGAAAGGTGCGGCGATGCTGTT CCCCGGAGGTAACCCACCCCTTGGAGGAGAGAGACCCCGCACCCGGCTCGTGTATTTATTACCG TCACACTCTTCAGTGACTCCTGCTGGTACCTGCCCTCTATTTATTAGCCAACTGTTTCCCTGCT GAATGCCTCGCTCCCTTCAAGACGAGGGGCAGGGAAGGACAGGACCCTCAGGAATTCAGTGCCT TCAACAACGTGAGAGAAAGAGAGAAGCCAGCCACAGACCCCTGGGAGCTTCCGCTTTGAAAGAA GCAAGACACGTGGCCTCGTGAGGGGCAAGCTAGGCCCCAGAGGCCCTGGAGGTCTCCAGGGGCC TGCAGAAGGAAAGAAGGGGGCCCTGCTACCTGTTCTTGGGCCTCAGGCTCTGCACAGACAAGCA GCCCTTGCTTTCGGAGCTCCTGTCCAAAGTAGGGATGCGGATCCTGCTGGGGCCGCCACGGCCT GGCTGGTGGGAAGGCCGGCAGCGGGCGGAGGGGATCCAGCCACTTCCCCCTCTTCTTCTGAAGA TCAGAACATTCAGCTCTGGAGAACAGTGGTTGCCTGGGGGCTTTTGCCACTCCTTGTCCCCCGT GATCTCCCCTCACACTTTGCCATTTGCTTGTACTGGGACATTGTTCTTTCCGGCCAAGGTGCCA CCACCCTGCCCCCCCTAAGAGACACATACAGAGTGGGCCCCGGGCTGGAGAAAGAGCTGCCTGG ATGAGAAACAGCTCAGCCAGTGGGGATGAGGTCACCAGGGGAGGAGCCTGTGCGTCCCAGCTGA AGGCAGTGGCAGGGGAGCAGGTTCCCCAAGGGCCCTGGCACCCCCACAAGCTGTCCCTGCAGGG CCATCTGACTGCCAAGCCAGATTCTCTTGAATAAAGTATTCTAGTGTGGAAACGCT Download Select all
Length	1848

CDS Information

Location	join(523..597,1822..1861,6212..6408,7182..7258,9357..9386, 9490..9552,13032..13059)
CDS Sequence	>lcl\|NM_001207012.1_cds_NP_001193941.1_1 [gene=PGF] [protein=placenta growth factor isoform 2 precursor] [protein_id=NP_001193941.1] [location=523..972] ATGCCGGTCATGAGGCTGTTCCCTTGCTTCCTGCAGCTCCTGGCCGGGCTGGCGCTGCCTGCTGTGCCCC CCCAGCAGTGGGCCTTGTCTGCTGGGAACGGCTCGTCAGAGGTGGAAGTGGTACCCTTCCAGGAAGTGTG GGGCCGCAGCTACTGCCGGGCGCTGGAGAGGCTGGTGGACGTCGTGTCCGAGTACCCCAGCGAGGTGGAG CACATGTTCAGCCCATCCTGTGTCTCCCTGCTGCGCTGCACCGGCTGCTGCGGCGATGAGAATCTGCACT GTGTGCCGGTGGAGACGGCCAATGTCACCATGCAGCTCCTAAAGATCCGTTCTGGGGACCGGCCCTCCTA CGTGGAGCTGACGTTCTCTCAGCACGTTCGCTGCGAATGCCGGCCTCTGCGGGAGAAGATGAAGCCGGAA AGGTGCGGCGATGCTGTTCCCCGGAGGTAA Download Select all
CCDS ID	CCDS73664.1

Protein Information

Protein ID	NP_001193941.1
Protein Name	placental growth factor
Molecular Wt. (Da)	14723
Protein Sequence	>5228 MPVMRLFPCFLQLLAGLALPAVPPQQWALSAGNGSSEVEVVPFQEVWGRSYCRALERLVDVVSE YPSEVEHMFSPSCVSLLRCTGCCGDENLHCVPVETANVTMQLLKIRSGDRPSYVELTFSQHVRC ECRPLREKMKPERCGDAVPRR Download Select all
Length	149
Uniprot ID	P31942
Ensembl Protein ID	ENSP00000265866

Post-translational Modification Information (Source : HPRD)

No matching records could be found.

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING) View

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
2321	FLT1	1297	NP_002010.2	in vitro	945 243 414 684 734
7422	VEGFA	1889	NP_001020537.2	in vitro;in vivo	1 279 677 312 086 890

Pathway Information

Pathway Name	Pathway ID
Focal adhesion	hsa04510
Pathways in cancer	hsa05200
PI3K-Akt signaling pathway	hsa04151
Rap1 signaling pathway	hsa04015
Ras signaling pathway	hsa04014

Structure Information

PDB ID	1FZV
Resolution	2
Method	X-RAY DIFFRACTION
Chains	A,B
Molecule	PLACENTA GROWTH FACTOR
Model	View

Domain Information

ID	Location	Description
cd00135	50-131	PDGF
cl00116	50-131	PDGF superfamily
smart00141	50-131	PDGF
pfam00341	52-130	PDGF
PHA02661	4-131	PHA02661

Ontology Information

HPRD ID	3406
Molecular Class	Growth factor
Molecular Function	Catalytic activity (GO:0003824)
Biological Process	Metabolism (GO:0008152); Energy pathways (GO:0006091)

SNP Information

View SNP Geneview Report

Drug Information

Uniprot ID DrugBank ID Name Type
P49763 DB08885 Aflibercept BiotechDrug

External Links

ArrayExpress GO
ICGC GO
Cancer3D GO
COSMIC GO
NCG GO
TSGene GO
Tumor Gene Family of Databases GO
CCDB GO
G2SBC GO
Osteosarcoma Database GO
RCDB GO

ArrayExpress	GO
ICGC	GO
Cancer3D	GO
COSMIC	GO
NCG	GO
TSGene	GO
Tumor Gene Family of Databases	GO
CCDB	GO
G2SBC	GO
Osteosarcoma Database	GO
RCDB	GO