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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
PHLPP2 23035 PH domain and leucine rich repeat protein phosphatase 2  16KIAA0931 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
23846336   2013Cell line : -

Source : -

Sample Type : CRC tumor and normal tissues

No. of Sample : 111

Stage : -

Real time PCR , Luciferase reporter assays Down-regulation--


Gene Details



NC_000016.9 (71678827..71757798, complement)

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Gene Type protein coding
Gene Family Serine/threonine phosphatases / Protein phosphatases, Mg2+/Mn2+ dependent, "Pleckstrin homology (PH) domain containing"
Description -  
Chromosome 16
Location 16q22.2
Start 71678827  
End 71757798  
Strand -  
Gene Sequence

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Length 78972  
OMIM ID 611066   
HGNC ID HGNC:29149   
Unigene ID Hs.709458   
Ensembl ID ENSG00000040199   
PharmGKB ID PA165450496   

mRNA Information


mRNA ID ?NM_001289003.1
Exon  
mRNA Sequence

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Length  



CDS Information


   
Location
CDS Sequence

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CCDS ID CCDS32479.1



Protein Information


      
Protein IDNP_001275932.1
Protein NamePH domain and leucine rich repeat protein phosphatase 2
Molecular Wt. (Da)0
Protein Sequence

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Length 1323  
Uniprot IDQ9P212
Ensembl Protein ID ENSP00000260766  



Post-translational Modification Information (Source : HPRD)


No matching records could be found.

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

No matching records from HPRD source could be found.

Pathway Information


      
Pathway Name Pathway ID
PI3K-Akt signaling pathway hsa04151


Structure Information


No matching records could be found.

Domain Information




ID Location Description
cd13322149-243  PH_PHLPP-like
cl17171149-243  PH-like superfamily
cd00143784-1033  PP2Cc
cl00120784-1033  PP2Cc superfamily
smart00332784-1031  PP2Cc
pfam00481872-1026  PP2C
COG0631825-1039  PTC1
cd00116313-606  LRR_RI
cl23707313-606  LRR_RI superfamily
cd00821157-239  PH
pfam12799645-684  LRR_4
cl19302645-684  LRR_4 superfamily
cd00116246-512  LRR_RI
pfam12799669-709  LRR_4
cl19302669-709  LRR_4 superfamily
pfam12799324-361  LRR_4
cl19302324-361  LRR_4 superfamily
pfam12799346-386  LRR_4
cd00116545-727  LRR_RI
cl23707545-727  LRR_RI superfamily
pfam12799439-476  LRR_4
pfam13855645-703  LRR_8
pfam13855526-606  LRR_8
pfam13855322-380  LRR_8
pfam13855393-451  LRR_8
PLN00113248-726  PLN00113
PRK15370467-759  PRK15370
COG4886292-579  LRR
COG4886470-729  LRR
COG4886304-609  LRR
PLN00113295-688  PLN00113
PLN03145800-1034  PLN03145
PRK15370304-579  PRK15370
COG4886446-749  LRR
PTZ00224808-1052  PTZ00224
PRK15387470-764  PRK15387
PLN03150293-365  PLN03150
PRK15370251-385  PRK15370
PLN03150321-403  PLN03150
PRK15387304-609  PRK15387
COG4886538-747  LRR
pfam13855668-725  LRR_8
pfam13855572-621  LRR_8
pfam13855502-559  LRR_8
PLN03150649-746  PLN03150
PLN00113263-355  PLN00113
PLN03210247-421  PLN03210


Ontology Information


   
HPRD ID11565
Molecular ClassSerine/threonine phosphatase
Molecular FunctionAuxiliary transport protein activity (GO:0015457)
Biological ProcessTransport (GO:0006810)  



SNP Information


View SNP Geneview Report   

Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO