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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
PINX1 54984 PIN2/TERF1 interacting, telomerase inhibitor 1  8PinX1, LPTL, LPTS, FLJ20565, MGC8850 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
26211574   2015Cell line : -

Source : -

Sample Type : CRC tumor and normal tissue

No. of Sample : 83

Stage : -

Immunohistochemistry Down-regulation-PinX1 protein expression is decreased in CRC, which may be a new promising tumor marker for CRC prognosis and 5-FU chemosensitivity.


Gene Details



NC_000008.10 (10622473..10697394, complement)

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Gene Type protein coding
Gene Family G patch domain containing
Description -  
Chromosome 8
Location 8p23
Start 10622473  
End 10697394  
Strand -  
Gene Sequence

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Length 74922  
OMIM ID 606505   
HGNC ID HGNC:30046   
Unigene ID Hs.490991   
Ensembl ID -   
PharmGKB ID PA165585852   

mRNA Information


mRNA ID ?NM_001284356.1
Exon  
mRNA Sequence

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Length  



CDS Information


   
Location
CDS Sequence

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CCDS ID CCDS47801.1



Protein Information


      
Protein IDNP_001271285.1
Protein NamePIN2/TERF1 interacting, telomerase inhibitor 1
Molecular Wt. (Da)0
Protein Sequence

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Length 328  
Uniprot IDQ9HBX8
Ensembl Protein ID ENSP00000255432  



Post-translational Modification Information (Source : HPRD)


Residue Type site
SPhosphorylation161
TPhosphorylation170
TPhosphorylation164
SPhosphorylation200

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

                              
Interactant Gene ID (Source: HPRD) Gene Symbol HPRD ID Ref Seq ID Technique References
7013TERF12975NP_059523.2in vitro;in vivo;yeast 2-hybrid11701125   
7015TERT1754NP_003210.1in vitro;in vivo11701125   


Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
smart0044324-69  G_patch
cl0261124-69  G-patch superfamily
pfam0158527-69  G-patch
pfam1265627-70  G-patch_2


Ontology Information


   
HPRD ID12185
Molecular ClassNot Available
Molecular FunctionTransporter activity (GO:0005215)
Biological ProcessTransport (GO:0006810)  



SNP Information


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Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO