CoReCG

Search results:

General Information

Gene_Symbol	Gene_ID	Gene_Name	Chromosome	Alias
PKN1	5585	Protein kinase N1	19	DBK; PKN; PAK1; PRK1; PAK-1; PRKCL1; PKN-ALPHA

Evidence
Gene
mRNA
CDS
Protein
PTM
Enzyme
PPi
Pathway
Structural
Domain
Ontology
SNP
Drug
External Links

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
22968445	2012	Cell line : - Source : Department of Pathology of Wrocaw Medical University. Sample Type : - No. of Sample : - Stage : -	Laser capture microdissection,FFPE-FASP,SAX fractionation,LC-MSMS,Label-free quantitation.	Up-regulation	4.7	-

Gene Details

Chromosome: 19; NC_000019.9 (14544166..14582679)
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Gene Type	protein coding
Gene Family	-
Description	The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
Chromosome	19
Location	19p13.12
Start	14433053
End	14471867
Strand	+
Gene Sequence	>gi\|568815579:14433053-14471867 Homo sapiens chromosome 19, GRCh38.p2 Primary Assembly AAAGGCCTCCGCCGCTCTCGGCTTGAACGCGTGGAACCGTTCTCCTCGGGTTCCCGCGCGCTCCAATGGG GGACCCCTCGGCAGCGTGCGGTCGTCTCGGGACCCGGAAAGAGGAAAGGTGGGGAGCCGATGGGGATGCT CCGGGCTCGGGAGACCGAGGGGGCGGACGGGCGGGACCCCGCAGCCCCGGGGGCCTCTGGGAACCCGTCC CCCCTCGGCCCCGCCCCCTCCCCGGGCGCCGACCTCCGGGGTCACGTGACCAGGCCCGGCGGCCGCTGGG GCCGGAGGGCGCGGCGCGGGGACGCGGCGGCCTGGCCAGGCGAGGCGGGAGCCGAGCAGGCCGGAGCGGG CCGCGCGCCGGGGAGGGTCGCGCCGCGCCCGCCCCCTCCCCGCCACGCCCGGGGCGCACGCGCGCTCCTC TGGCCGCCCCTCCCTCCGCGCGGGGACCCCTGGCGGGCGGCAGGAGGACATGGCCAGCGACGCCGTGCAG GTAGGCGCACCTGCGTCTGGAGTCCCGGGGCGACCGGACGGCGCCGGCGGACCCCGCCCGCGCGCTGCCG GGGGAGCCCCCCCAGCCCCCGGAACGGGACTCGGGTGACGATGGCAAGGGCGGGGGCCTCCGGAGCGCCC GGCGCCCCCTCCCTGGGCCGGGACTGTGGAGCCAGCGAGGCCCCCTTCTCGGCAGGTGGCGATGTGGACT GGGCTGGTTTGGGGGCGATCCCGGAGGCAACCCCTGCTACACCCTCAAACTCGGCCTCTCCTGGAGAACT AGAAGGGGCGCGGCGGAGGCTCTACTTCGGGTGTCTGTGGCTGGCTGGGCGTCCCAGTGCCTCTCGTCCG CCCCCAAACTCATCCCCCTCCCCAGGGTTGGGTACCCGGCAGGTGCCGCTCCACCTGGGGCACGTGCCTG GCGCAGTGCCCTGGGAGGGGAGGAGGCTGCTGGGCCCGGCCCGTGCCCTTCCCCCGCATAACAAAGCTCC AGCCACCCCCGCCTCTAGACAGCTTTATGATGTTCCAGACGCCACCCAGATTGGCACCTGTTGGCGGAAG TACCCGAGTCACTGCATTAGGTCGGGGGAATGGGGACCCCCACTCCCACCCTTGGGCTGTCAGGTGGAAC CTTCTCCTGGGTGGGGAGTGTCTCAGTCAACAGGCCAGGGATGCTCCCATATATAGAATCCTACTTTTTT GCATGGTGGCTGGGCATGGCTGGGTCACCCCCACCCTGCTAACACACACACGTGACTGGCACCAGCCTCC CGCCCAGCCAGATTCCCCTTGTGCCACCTGGTGGGGATCACTGACCTGGACTCATCTTCCCCGTCTGTGA CAAGCACGGCCAGGGTGACTGCCAACCTTCTTTGGTTCAAGTGACCCAAATCTGAGAAATGTCTGTGCCT CAGTGTCCCCATTAGCACCTCACCATCCAGTTCATTGTCCTGTGGTTGTTGTGTAACTGGGTTCTCGTCT CCTTCTGCACCTGCCCCCGGCCCCTTTGTGTCTCCCCGGTAACCCCCGGTCCCTCCCGCCTTCCCAGTCC TGCTGATGGCCTGCCGGCCTTGCCGAGGAGCTGGGCGTATCTGGTGTTGCCGATCACACAAGGTCAGACC TCAAGGCCGGGATGGGCCGGGGTCCCTGCCTCTACCCCCGGCCCAGGGAGGGCTGTGTAGGAATCCCCGG GTGCATGCATGCGCTTGGCGCATCCCACACATGACCCAGACAGGCTGTGATTCCTGCAACGAGGCTGGAC CCACGCCCTGGTCCCCCCTTCCCATCTCCTCCCCAGTCTCTTCCCCGCTCCTGGTCATCCCTCTCTCATG GTTGCTTGGGCCTGCTGCCCTGTCCCTCTGTCTGTCCCAACGTGTGCCTGTCTGTTCTGTGTCCTGCAAA CGGATGTCCTGTCCAGATTCCGGAAACGCCCAAGGCATTGAAATCTCCGGATGTGGGAGTCTAGGTCCCT GGCTGCTCTGGCAAGATGGGGATTATGGGAGGCAGGTCCTCTGGGTCTGAGGTCTCCGCTCCATGGTGGG CAGCGGAGGAGCAGGGGTTCTCCATAGGACAGGCCAGGCCAGGGCCCTGAGTCCTGGGTTTGCCTTGCTG GCCCTCAGGTGACCCCTGTGCCTTGGGTAGAAGTGAGTCACTCAGGGGAGGAGAACCCAGGAGCCCAGCC TCCCTCCCTCTGTGCATTACAGACCTCAGCTGCTGGAGGTGGGGCTGAGGGAGGCCACCTCTCCTCTCTG CCTGGACTTCCCCAGTTGAGCTGGCCCCGCTCTTGGCTGTGTCCTCCCTCTGCCTGCTGGGGATGGGGTG GGGCCTTCTGAGCGAGGGTGGTATTTGGTGAGCCTGGGCTTAAATTCCAGCGCTGACACTTCCTCGCTGT GTGTCCTGGGCCCAGTGCCTTCGCCTCTCTGAGCCTCGGTTCTGACCTAGGAAAAATGGGACTAAGAGGG TGTTCATGGGAGAGAGAGAGACCGAGACCTTGCCAGCACTTGGCAGGCAGGGCTGCTGTGAAGTCGTTAC TGGTAAGCGTCCTGGTCAGCAGCTCAGGGTGTGAATCTGTGTCCTTATTGATTGATTTACTGATTTATAT TTATTTATTTTAGAGGAGAGAGTCTTGCTCTGTCACCCAGGCTGGAGTACAGTGGTGCGATCCTATGTCA CCGCAGCCTCGATTTCCAATTTCCGGGGCTCAAGTGATCTTCCTGCCTCAGCCTCCCAAGTAGCTGGGAC AAAAGGCACAGACCAACATGCCTGGCTAATTTCCTTTTACTTTTGTAGAGACAGGGTCTCGCTCTGTTAC CCAGGCTGGAATGCAGTGACGAGATTCTTGTTCACTGCAGCCTCAAACACCTGATCTACAGGACTACAGG CATGCACCACCACACCTGGCTAATTTTTTTTTCTTTATTTTTTTAAATTGAGACTGGGGTCTCACTCTGT CACCCAGGCTGGAGTGCAGCGGCATGATCTCTGCCTCCTAGACTCAAGCCGTTCTCCCACCCCAGCCTCC TGAGTAGCTGGGACTACAGGTGCACACCACCACGCCTGGCTAATTTTTGTATTTTTAGTAGAGTCAGGGT TTCGCCATGTTGCCCAGGCTGGTCTTGAAATCTTGAGCTCAAAGTAACCTGCCCGCCTAGGCCTCCCAAA GTGCTGGGATTACAGGTGTGAGCCACTGCCCCCAGCCTTTCTTTTTTTCTTTTCCTTTTTTTTTTGTGAT GGAGTCTCGCTCTGTCGCCTAGGCTAGAGTGCAGTGGCTTGATCTCGGCTTACTGCAAATTCTGCCTCCT GGGTTCACGCCATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAAACGCCCGCCACCATGCCCGG CTGATTTTTTTGTGTTTTTAGTAGAGACAGGGTTTCACCTTGTTAGCCAGGATGGTCTAGATCTCCTGAC CTCGTGATCTGCCTGCCTCGGCCTCCCAAAGTGGTGGGATTATAGGCATGAGCCACCGCGCCTGGCCTCT TTTTTTCTTTTTTGAGACAAAGCCTGGCTCTGTTGGCCAGGCTGGAGTGTGATGGTGTGATCTCGGCTCA CTGGAACCTCTGCCTCCTGGGCTCAAGCCAGCTTCCCACCTCAGGCTCCCAAGTAGTTGAGACTGCAGGC ACATGCCATCACACCTGGCTAATTCTTACATTTTTTGTAGAGATGGGGTCTCACCGTTATTGCCCAGGCT GGTCTCGAACTCCTGAGCTCAAGCAGTCCTCCGGCCTTGGCCTCCTAAAGTGCTAGGATCACAGGCAGAG AGAGCCACCACACCTGGCCAATACTTTTTTATTTTTTGTAGAGATTTTTGTAGGTCTTGCTGTGTTGCCC AGACTTATCTCCAATTCCTGACCTCAAGCACTGCTCCTGCCTCAGCCTCCCAAAGCGCTGGGATTACAGA CGTGAACCACCACACCTGGCCAAATCTATGACCCTTAACCGTAGGCTTCTCAGCCTTAGCACTACTGACA TTCAGGGCTGGGTCATTCTTTGCAGTAGAGGCTGTCCTGTGCACTGCAGGGCGTTGAGTGGCATCCCTGG CCTCACCCTGATAGAAGTCACCTCCTTACCCACAGTCAGGACAACCAAAAATGTCTCCGGATGTTGCCGC ATGTCCCCGGGTATGGGGAGAAAATCTCCCCTCAATGGAAAACTGTTACTGGCCAGGCACAGTGCCTCAC ACTTGTAATCCCAGAACTTTGGGAGGCCGAGGCTGGCTGATTGCTTGAAGTCAGGAGTTTGAGACCAGCC TGGCCAACATGTGAAACCCCGTCTCTACTAAAAATACAAAACATTAGCTAGGCGCAGTGGCACGTGCCTG TAGTCCCAACTACTCAGGAGGCTGAGGCAGGGGAATTGCTTGAACCCGGAAGGTGGAGATTGCAGTGAGC CGAGATTGCACCACTGCACTCCAGCCTAGGCGAAAGAGCAAGACTCTGTCTCAAACCAACGAACAAAACA TACTACTGTGACTTCCTTGAGCCTCAGTTTCCTCACCTGTGAAGTGGGGAGTTCTTGGCAGCTGCTCAAG ATTTGTAGTGAGGGTTGGGAAGATGGTGGGAGTGATACACTTGGTCTGTGGCATTCCTCCCTGGGGGCAG CTGCGCTTGAGATCAGTCACGAGCCAAGGATAACATTCCTTGTCTGTGAAATGGATGCTCCCAGCTGAAG GAGATAACCCCAGGGGGCCATTTCCTAGCCAGCATTTGGAATCTGGGTGCTCTTGTTTTAAATCAAGGCC CTGGCCACGGGGCAGTGACTCACACCTGTAATCCCAGCACTTTTGGAGGCCGAGGCAGGAGGATTACTTG AGGCCAAGAGTTCGAGATCAGCCTGGGCAACATAGTGAGACCCCATGTCTATGAAAAATACAAAAATTAG CCAGGTGTGGTGGCGTATGCCTGTAGTCCCAGCTGCTCGGGAGGCTGAGCTGGGAGGACTGTTTGAGCCC AGGAGGTAGACACTGCAGGGAGCCATGATCACACCACTGCACTCCAGCCTGGGCAACAGAGTAAGACCCT GTCTCAAAAAAAAGAAAAAAAGTTACATGAGATATTCAACTTTACTGTAAAATAGCTTTGTGTTAGACGT TTTTGCCCAACTATAGGCTTGGGTAAGTGTTCTGAGCACATTTAAGGTAGGCCAGGGTGAGCTATGATGT TTGGTAGGTAAGATATATTAAATGCATTTTTGACTTATGATATTTGCAACTTATGATGAGCTTATCAGGA AGTAATGCCATCATAAGTTGTTCTTGAATGTTACTGTGTGCTTAGCAAGTGGTTTTGTAGGCTGCTGATT TGGGGCATTCTTTTTTTTTTTTTTTTTTTTTGAGATAGAGTCTCACTCTGTCGCCCAGGCTGGAGTGCAG TGGTGTGATCTCGACTCACTGCAATCTCCACCTCCTGGGTTCAAGCGATTCTCATGCTTAGCCTCCCAAG CAGCTGGGATTACAAGCACGTGCCACCATGCCTGGCTAATTTTCATATTTTTAGTAGAGACGGGGTTTCA TCATGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCACGTGATCTGCCTCGCTCATCCTCCCAAAGTGCT GGGATTACAGATGTGAGCCACCACGCCCGGCGTGATTTTGGAAATTGGAAATTCTTTTTTTTTTTGAGAC GGAGTTTCGCTCTGGCGTGCAATGGCACGATCTTGGCTCACCTCGACCTCTGCCTCCTGGGTTCAAGTGA TTCTGCTTCAGCCTCCCAAGTAGCTGGGATTATAGGCATGCACCACCAAACCCGACTAATTTTGTATTTT TTTTTTTTTTTCAGTAGAGACGGGGTTTCTCCATGTTGGTCAGGCTGGTCTCGACCTCCCGACCTCAGGT GATCCACCCACCTCGGCCTCCCAAAATGCTGGGATTATAGGCGTGAGGCACCGTGCCCGGCCTGGTTTTG GAAATTCTTATCCCAGTCCCCCAGTGCTGTCCCCTAATTGTGTTGGCCTGAGGGAGGTGCCACTGGGCTG GCTGGGACCCCGGGCCTCTCAGCTATGGTCAATAACAGTTGGCGACTGGACTGAGAGGAAGCAGGAAGTT GGGAGGGCCCGTCTGCAGGAAAGGGGCCTCACCTCTGAAGAAGTGGCTGTTCTGACCCTGAAGGGGAAGC CGGGGACAAGGGGTGGCTGGGAGAGTCTGGAGGGACATATGCAGGTAGTCGCAGGGCTGGAGGTCTGTGG GAGCATGGATGTGCTGCAGGGGCCTCGGGGAGCGTGCATATGTGTGTGAGCATGTGCACACGCATGAGCA TGTGGGCCATGCCCTCTCGGGCAGGTGGGAGTGTGTCTTGTATGGGTTCTAGAGGGAAGCTCATAAGCAC TTGTATGTGTTTGCAAATAAGTGCATATGTGGTAGGCATGGGAATGGGTACACTGTGAGCCCATTTTCCA GGCACACACCTGCAGGTGTAGAAGTGTGCACCTGTGTGTGGATCTTTGTTTCATCCACACACACAGGCAT GGGAGTGTGCACACATGTGAGCCTGTGTTGCAGGCACACACCTGCAGCCATAACTGTGCAAACACAGGCC AGGCGCGGTAGCTCACGTCCAGTAATCCCAGCACTTTGGGAGGCTGAGGGGGGCGGATCACCTGAGGTCA GGAGTTCGAGACCAGCCTGGCCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCTGGGC GTGGCGGCACATGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAAGAGAATTGCTTGAACCTGGGAGG CGGAGGTTGCAGTGAGCCAAGATCACACCAGTGCACTCCAGCCTGGGCAACACAAAGGGAGACTCTGTCT CAAAAAAAAAAAAAAAAAAAAAAAAAGGAAAGAAAAAGAAAGCGTGCAAACATTTGTGAGCCTGTGTTCT GTGCATATCCACATATGTATTTGAAAGTTAGTGCACACTCAAGTCAGCCCTCGGAGCCTGCGTCCCCTCA TGGATACACCATGAGTGTGTGAATGTACAAACTGCCTGCACCTTGGACATTCTCTAGGGACAGGGAGCAA GGACTGTCCCTGGGTTTCATCTAGAGGAACAGGAGGTCCCTTAGATGCCCTGGAGTTGGCCCCGCGCGAG GGGTGCTGGGAGTTGACAGGAAAGAGGAAGTGGCAGCCGAGAGGCCCTGGTGGGGCTGAGGTTCAGGAAG AGGGCGGGGCCCTCAGCCCGGACCCAGGATGGCGGAGGCCAATAACCCCTCGGAGCAGGAGCTGGAGGTG GGGTCCAGGGTCCCTGTGGGGGCAGGCAGAAGGGGGCCCCAAGTGGCACAGGCCAGTAGTCCTTCCCCGG GTACTTCTCAGTTTGGGAACAAGGAGAGGAGATGGGGCACTGGCCTCAGAGTTCTCTCTCTGGAGGATGA GAGTATCCAGTGCCCTTCGGGGCTCCCAGATTGGGGAGAGACAGAAGGAAGGAGACCGGGCTCTGTTCTT TAGGGTCCCAGTTGTTGAACATAGGAGAAGAGCAGATGAGGGTCTTCAAGACCCCATAGTTTGGGGGTAC AGCAGAGAGAAGACTTGGCCTGCCCTTGGGATACCCTAGTTTTGGGGGTGTAGCCAAGGAAAGATGAGGC CTGCCCTCGGGATGCCATAGTTTCAGGGTACAAGTGAGGGAAGATGGGGCCTGTCCTCAGGACCCTGTAG TTTTAGGGGTACAGCAGAGAGAAGACAGGGCCTGCCCTTGGGCCCTCTTAGTTTCGGGGAGCAGCAGAGA AAAGAAGGAATCTTCCCTTGGGACCCTCTAGTTTGGGGGAGGCAGCAGAAGGGAGACAGATCTTATTCTT GAGACCCCCTTAATGTGGGGGACGCTGTGGTGGTGGGGGTGACAAGGCCCTGCTCTTGAGACCTCCCAGT TTGGGGAGGTCAGGAAGCAGTGGCAAGGCCTCGTCACCTTCCAGTTTTGGGAGTCAGAGGAGGTAGAGCA GGCCCTGTCTTGGGAGCCCCAGTCCAGGGCAGAGGCTGGGCCAGGCTGGCTGCATGTGGTCTGCACCTGG AGTTCTCCTAGCTCCACTGACCCTGTTCTGTCCTCCGCAGAGTGAGCCTCGCAGCTGGTCCCTGCTAGAG CAGCTGGGCCTGGCCGGGGCAGACCTGGCGGCCCCCGGGGTACAGCAGCAGCTGGAGCTGGAGCGGGAGC GGCTGCGGCGGGAAATCCGCAAGGAGCTGAAGCTGAAGGAGGGTGCTGAGAACCTGCGGCGGGCCACCAC TGACCTGGGCCGCAGCCTGGGCCCCGTAGAGCTGCTGCTGCGGGGCTCCTCGCGCCGCCTCGACCTGCTG CACCAGCAGCTGCAGGAGCTGCACGCCCACGTGGTGCTTCCCGACCCGGCGGCCACCCACGGTGAGCTGG GATGCCTCTGGGGATGCGGGACTCCAGGGATTCCACTGCTCACTGGCTCACCCATGGTCTCCAGAGCCAG GTTAACCCATCTCCACGGACCCCCAGGGAGATGCATGCCATGACCCCCGTAGCCACCAACACCCAGAGAG GTGCATACAGCCACACCAGCACCCGGTAACACTCAAGACCGTGCATGCTGTCACATGAATACCTCTAGAC ACAGCCACGCCAACACCCAGGCAACATTCAAGGATGTGCATGCAGTCACACAAACACCTAAAAAAACAGC CACACCAACACCCAGGCAACACCCAAGGGTGCACATACTGTCACACGAATACCTCCAGACACAGCCACGC CAACACCCCAGGCAACACTCAAGGATGTGCACACTGTCACACGAATACCCAGAAACTCCCACAGTTACAT GGATGATAACCAAAGACTGTTTATTTTTGTTTTTGTTTGGAGACAGGATCTTGCCTTGTCACCCAGGCTG GAGTACAGTGGTGTGATCAAAGCTCACTATAGCCTCAATTTCCTGGGCTCAAACAATCCTCCCACCTCAG CCTTCCAAGTAGCTGGGACTAAAGGCATACACCACCATGCCTGGCTAATTTAATTTTTTTTTTTTTTTTT TTTTTTGTAGAGAAAGGGTCTTGGTATGCCGCCAGGGCTTGGCTAGAACTCCTGGCTTCAAGTGATCCTC CTGCTTTGGCCTCCCAAATGCTGGGAATACAGGCGTGAGCCATTGCACCCAGCCTGTTTTTTAATTTAAA ACATTTTTATTGGTTTTAACATTTTTTTTCTTTTTGAGATGGAGTCTTGCTCCATCACCCAGGCTGGAGA GCAGTGGTGCAATCTCAGCTCACTGCAACCTCCACCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTC CTGAGTAGCTGGGACTATAGGCTTGCACCACCACGCCCGGCTAATGTTTGTATTTTTAGTAGAGATGGGA TTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAACTGATCCACCCACCTCAGGTGATGTGC CTCCCAGAATGCTGGGATTACAGGTGTGAGCCACCTCACTCAGCAGCTTGAATTTTTTTTGGTGGGGAAG GACAGAGTTTTGCTCTTGTCACCCAGGCTGAAGTGCAATAGCACGATCTCGGCTCACTGCAACCTCCACC TCCCAGGTTCAAGTGATTTTCCTGCTCCAGCCTCCCAAGTAGCTGGGATTATAGGCATGAGCCACCACGC CTGGCTAATTTTTGCATTTTTAGTAGAGACGGGATTTTGCCATGTTGGCCAGGGTGGTATTTAACTCCTG ACTTCAAGCAATCCGCCTGCCTCGGCCTCCCAAAGTGCTGGGATTATAGGTGTGAGCCACTGCGCCCGGC CTCAGTCATTTCTGCACCCAGGGTCCCCTCAAGCATCACACCACTCTCCAGAGACTCATGCAGACACATG CATCCGGATGTGCCAACACCCGGAGACTCAGTCATACCAACCTGGAGATCTGAACTCACAGTTGTAGCAA CAGTCAGAGATGTACGCAGAGCATCTCCCAACACCCACAATCTCAGACAGTCATTCTAACACATGGCGTC TCACAGAGTTACACTAACACCTAGGGAAACACACACTCAGCCATGCCAACACCCTGCAGCTCACAGATGG CACCACTCCCACACCCATAGGCTCACACAAGCCATGTACGTAGTTACTCATGGGCCTCTCAAATGCAGTG GACCCAGCACCAAGGACACACTAACACACCTGGGTGCTCGCCTGCACTCATTCATCCTGGGTTCTGCCCC AGCCCCGAGGGGTTTCCCTGGGAGGGTGGGTGGGTAGACTGCTGGGCCCTGGTGTCCCCCTGCCTGCCTG TCTGCTGGCCCCCAGCTCCCCCTCCTCCATGCCCCAGGGGCAATGCCCAGGCTGGGCTGAGGATGAAGCC TCCCAGGCAGGCCGAGGTGAGGATGCGTGGTGACTCTCTCCCACCTGTCGCCTCCAGATGGCCCCCAGTC CCCTGGTGCGGGTGGCCCCACCTGCTCGGCCACCAACCTGAGCCGCGTGGCGGGCCTGGAGAAGCAGTTG GCCATTGAGCTGAAGGTGAAGCAGGGGGCGGAGAACATGATCCAGACCTACAGCAATGGCAGCACCAAGG TGAGGCAGCACGTGCACACACACTGTGTACACACACCACACCTGTGTGCGTACAGTCCACCCACATGTGC ACACCTACCTGCATGTGTACACATGTGTCCCTGTGTGCACACGCCCACTCAAATGTGCACCCACACCTGC GCATGCACACCCCACACGTGCACACCCATCCGCATGTGTACACACCTGTCCACGTGTACACACACCCACT CAAGTGTGCACCCACACCTGTATGTGCACACACTCACTGGCATGTACTCCCACATCTGTACATGCACACA CCTACCTGCGTGCATACACGCTCACCCACATGTGTACACACCCCTGCAAATGTGTACACACATATGCATA CACCCACCACACGTGCACACACCTGCATGTGTACACACCCTTGAACGTGCACACACAGCTGCACGTGCAT GCATACTTGCACACACCCACATGTGTGTATACCAGCATGTGTACATACACCCCCCATGTGCACACACACC TGCACATGCACACACACCTGCCTGTGCACCTGCACCTGCATACACATTTGCAATGCACATGCACATGTAC ACACCCACACGTACACACCCACCCGTGTATCTGCACACACACCGCACATGTATGCACATGCCTGTGAGCA GATCACAGGCTGGGGGCATAGGGTGCAGCCTACAGCTGCCCCCATGGGAGGCTGGGAGCCTTTGGATTGG GGACATACTGGCTGATGGGTGTAACTTGGTGTCAGGACTAAGGCACAGGCAGCTCATGGGGGCATATGGG AAGCATGACTATGGGTGATGTCAGACAGACGTGGCAAATTGTCTCCCCTCCTCCCACAGTCCCCTGCAGA GCCTCAGGCCCATCCACAGTCAGGGCAACATGCCGCCTCTCACTGCTGACGGTGTGTCCTGTTACAAGCA CACACAGTCATGTCATACCTTGACACACACACACCATCATAACATCTAGACACACACACACACATGCTGT CATAACATCTAGAGACACACAGTGGTAACAACATCTAGCAACACATGGAGAATCCCACCACAGCCACATC TGGACACACACACACACTCTTACATTCATACCCAGAGACTGGTGCACAGACACACACACATCCCCCGTCC TGCCAATCAGTCCCAGGAACACACAGGTCTCTATCAACACCCAGAAATTCTGACACCACAAGCACAGGCC AACCTACAGCTAGAGGATTAATGTCCAGACCCACAGGCTGGTGTGCGCATGTCCTTCCACGTGAATGTCA CATGGGAGGACAGACTGCATGGATTTTTTTAATGACACTATTTTATTTATTTTTTGAGACAGAGTCTCAC TCTGTCGCCCAGGATGGAGTGCAGTGGCGTGATCTCGGCTCACTACAACCTCCGCCTCCTGGGTTCAAGC GATTCTCGTGCCTCAGCATCCCAAGTACCTGGGATTACAGGCGCATGCCACCACGTCCCGCTAATTTTTG TATTTTTAGTAGAGATGGAGTTTCACCATATTGGCCAGGCGAGTCTCGAACTCCTGACCTCAGGTGATCT GCCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGATGTGAGCCACCTTGCCTGGCCTAACATTATTTTA TTTATTTAATTTATTTTTATTTTTATTGAGACAGGGGTCTGTGTTGCCCAGGCTGGACTCGAACTCCTGG GCTCAAGCATTCCTCCTGCCTTGGCCTCCCAAAGTGCTGGGATTACGGATGTGAGCCACTGCGCCCCATT TATCAATTGGTGGACATTTGGTTGTTTCCACCTTTTTAGCGATTGTGAGTAGTTTTGCTATGAACACCTG TGTACAAGTATTTGAACACCATTCTATGAAAATTTAAAACCTAGATCAATTGTATATCTTTTACATGTAT CTGAGCGTTATACAAAAAAAGAATAAGAGTTTCTCACCCCCTAAGAATTTCTGCCCCCCGCCCTGGGGGT AATACTGACCCAGTGAAAATGAATAGAGTAGGCCAGGCGCGGATCCCAGCACTTTGGGAGGCTGAGGCAG GCGGATCACTTGAAGTCAGGAGTTCAAGACCAGCATGGCCAACATGGTGAAACCCGAGCTCTACTAAAAA AATACAAAAATTAGCCGGGCGTGGTGGCACATGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAG AATCGCTTGAACCTGGGAGGCAGAGGTTGCAGTGAGCTGAGATCACACCACTGCACTCCAGCCTGGGTGA CAGAGCGAGATTATGTCTCAAAAAAAAAAAAAAAAAAGCTGGGCATGGTGGTGGGCGCCTGTAATCCCAG CTACTCAGGAGGCTGAGGACTCCATGGACTACATCATGCCACTGTATCCAGGAATGCATGGAAGTACATT TATTTACTTATTTATTTATTTTGAGACAGGGTCTTGCTCTGTTTCCCAGGCTGGAGGGCAGTGATGCAAT CTCAGTTCAATGCAGCCTCCAACTCCTGGGCTTGAGTGATCTTCCCACCTCAGCCCCCTGAGTAGCTAGG ACCACAGGTGCACACCACCACGCCCAGCTAATTTTTGCATTTTTTTGTGGAGACAAGGTCTTGCCATGTT GCCCAGGCTGGTCTTTAACTCCTGAGCTCAGCAGTCCACCCGCCTCAGCCTCCCAAAGTGCGGGGATTAC AGGCATGAGCCACCGTGCCTGGCCTGCAAATGCATGTTGTTACATCCACATGTGAACACTCTGCCACAGT CACCTAGGACCTGCATGGTGTGGCTAGACCCCAACCACCTAGCCTTCCTCTCTCAGACTGTCTCTGCCTC CAGGACCGGAAGCTGCTGCTGACAGCCCAGCAGATGTTGCAGGACAGTAAGACCAAGATTGACATCATCC GCATGCAACTCCGCCGGGCGCTGCAGGCCGGCCAGCTGGAGAACCAGGCAGCCCCGGATGACACCCAAGG TGAGTCCCTTGCTTCCAGGCAGCTTAGCCTGCATCTCGCCTTGCAGGGCTCAGCCTCCAGCTCCATAATG AGTCCCTTTCTGGGGCAGGGAGGTGGGTCCTGTGACCCACTGTGAGACTTCAACACATTCCTGACCCTCT CTGGGCCAGAGCTTCCCATTTTGTCCCATGCAAAGTTTGGATTACATCAGGGGTTGGTAAATTACCACCT TCAGACCAAATCTATCCATTGTCTTTTTTTTGTCAATAAAGTTTTATTGGTACCCAGCCACGCCCATTCA TTTACTATGTTTTTGACTGCCTGACTATTCTGAATAATGACCCTGGCACTTGGTCACAGAGAGTCAGACA CTCACAGTCACACTGTGTCCACATGTGTCACTCACCTGGACACCAATAACACAGACACAGTTCCAAGGAA GTTGATAGTCACAGGTATGTTGCCTTATAAACACAGTCTCGGCTGGGTGCAGTGGCTGACGCCTGTAATC CCAGCACTTTGGAAACCGAGGCGGGCGGATCATTCGAGGTCAGGATTTCGAGATCAGCCTGGCCAACATG ATGAAACCCTGTCTCTACTAAAAATGCAAAAATCAGCTGGGCGTGGTGGCACGCAGCTGTAGTCCCAGCT ACTCAGGAGGCTGAGGCAGGAGAATCACTTGAATCCGGGAGGCGGAGGTTGCAGTAACCCAAGGTCGCCC CACTGCACTCCAGCCTGGGCAACAGAGTGAGACTCTGTCTCAAAAAAACACACACAAAAAAACACACAGT CTCACTGTCACCCCTAGACCTGCTGCCACATGGCGCTTTATCAGTCACTGGGACTTTTAGGAATAAAGTC ATCCAGTCACCCATCCTTGCGACAACACCCAGAGACAAAGGAATGTGTGATCCTACCATCACACATAGTC ACTGTGAAGTCCATGTGGATATCCACAGTACAGGCACACAATCACGTGCACCGTCGCACTGACACACACT GCAGGGACACACTTTTTTTTTTTGTTTTTTTTTTTAGATGGAGTCTCGCTCTGTTGCCCAGGCTGGAATG CAGTGGCACAATCTCTGCTCACTGCAACCTCTGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCC TGAGTAGCTGGGACTATAGGCGCCCACCACCACACCCGGCTAAATTTTGTATTTTTTTTTGAGACGGAGT CCTGCTCTGTCGCCCAGGCTGGAGTGCAGTGGTGTGATCTCGGCTCACTGAAAGCTCCGCCTCCTGGGTT CATGCCATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACGGGCACCTGCCACCACGCCTGGCTAAT TTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTAGCCAGGATGGTCTCGATCTCCTGATCTCAT GATCCGCCTGCCTTGGCCTCCTGAAGCGCTGGGATTACAGACTTGAGCCACCACGCCCTACCAATTTTTT GTATTTTTAGTAGAGACGGGGTTTCACCATGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCG CCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGTGCCTGGCTGACACACTTTTTTT GTTTAGACAGGGTCTTGCTCTGTTGCCCAGGCTGGAATGCAATGGCGCGATCATAACTCACTGCAGGCTT GACCTTCTGGGCTCAAGCAATCCTGCTGAGTAGCTGGGACCATAGGCGTGTGCCACCACACCCAGCTTAT TAAAAGAAATTTTTTTTTTGTAGAGACTAGGTCTTGCCCAGGCTGGTCTCAAACTCCTGACCTCAAGTGA TCCTCCTGCCTTACCCTCCCAAAGTGTTGAGATTATAGGCGTGAGCCACTATGCCTGGCCTGTGCCCCTT TTCTTGACCCTGTGCTTGGGCATAAATGCATTTGTGTCTGTGACTGTGTTTCTCTGCCCCTATAATGGTG TCCCTGTGCCCAAGATGACAGGGCCGTGTCTGTGTAACAGAGTCTGACTCATGACAGTGTCTCTATGTGG CAGGGTGACTACATCTTTGTGACAGAGTATGTGTTCCTCTGGTGATAGTGTGCCTACGCTGGTGACAAAG TGGTAATGCCATGTGTCCCTGTGGGCGACAGTGTGACAGTGTCAGTGCGACAGTGCCTGCCTTACTCTCC TTGGGCCGCCATAACAAAGTCCCATAGGCTGAGTGGCTTAAACAACAGACATTTATGTTTTTCACAGTTC CAGAGACTGGCAGTCCCAGATCAGGGTACCAGCATGGTCGGTTCCTGGTGAGGGCGCTCTTCCTGGCTTA CAGATGGCTTCCTTCTTACTGCTCCCTCACAGGGAGAAAGAGCCTTAGTGTCTCTTCCTCTTCTTATTTT TCATTATTAGTTTTTTGAGACAGGGTCTTGGTCTGTCACCCAGGCTGGAGTGCAGTGGCGTGATCACAGC TCACTGCAGCCTCGACTTTCTGGGCTCAAGTGATCCTCCTCGTTCAGCCTTCTAATAGCTGGGACTACAG GCACACGCCACCATGCCTCGCTAATTTATTTTTTATTTTTAGTAGAGACAAGGTCTCTCTATGGTGCCCA GGCTGGTCTCAAACTCCTGGCCTCAGGTGATCCTCCTGCCTCAGCCTCCTAAAGTGCTGGGATTACAGGC GTGGACCACTGCACCCAGCTTCTTCCTCCTCCAATAAGCGCGCTAATCGCATCATGATGGCCCTCCCTCC ATGACCTCCTCTAACCCTAATTACCTCCCAAAGGCACTTGGAGAAGTCCAAGTGCCATCCCACTGGGGAT TAGGGGTTCAACATAGGAATTTGGTAGGAGACAAACATTGAGTCTCTTAACAGTGTCTTTGTGACTGACA CCGTCTGTGTAAATGTAGTATGCTGTGGTTGTCCAGATGTCCATGAGTGTCACCATGCCTGGTTGACTGT GTAACCTGGTGACTGTTCATTGGGGAATGAGGTGTGTCAACACGGGTATGACAGTATTATTATTTTTTTT TAATGACTTAGAGTCTCACTCTGTCACCCAGGCTGGAGAGCAATGGCGCAATCTTGGCTTACTGCAACCA CCGCCTCCGGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCTCAGTAGCTGGGATTACAGGCATGCGTCAC TGTGCCCAGCTAATTTTTGTATTTTTAGTAGAGAGGGTTTCACCATGTTGGTCAGGCTGGTCTCAAACTC CTGACCTCAGGTAATCCACCCGCCTTGGCCTCCGAAAGTGCTGAGATTACAGGCCTGAGCCGCCATGCTT GGCCTATGATTTAGATGTTCCTGTCTGTTTGGGTGACAGCCCCTGGGTGACAGTGTCTGAATCTAGATAA TGTGGCTGTCCCTGGGGGCCACAATGTGCCTGCGTCTGTCCCTGTGCAAATCACTGGAGGTGAAGAGGGA CCGTGACAATGTGTGTGTCGGTAAGCGTGGGGTGACAGTGTGCCTGTGTGTCATTGCTCAGACTGTCCCC TGTAACAGGGTAACTTTTTCCCTAGGACTGGCCCTGTGAGTGATGGTGTTTGGATAAAAGAGTCTGGGTG GAAGTGTGGCTGCCTGCAGGTGACAGTGCGACAGTGTCACTGTGCCTGCCCCTTGGATGAAGCGTGATGC ATCTTCATGATGGTTTGTCTGTGGCCCGTGCCTGTTCCTGCGAATGGCTGTGTCTGCGACTAGGTTGGTG GGGCGCTGCAGGCTAGCCTCACTGCCCTGTATTCCACGCTCACAGGGAGTCCTGACCTGGGGGCTGTGGA GCTGCGCATCGAAGAGCTGCGGCACCACTTCCGAGTGGAGCACGCGGTGGCCGAGGGTGCCAAGAACGTA CTGCGCCTGCTCAGCGCTGCCAAGGCCCCGGACCGCAAGGCAGTCAGCGAGGTGAGGGGCGGAGCTTTCA TTAGAGGCGGGGCTTCAGCAAGGGGCGGTGCTTCAGCAAGCGGCGGGGAGTTCACCAGGAACACCCACGG TGAGGGGTGGAGCCTCAAAGGGGGTGGGACCTTCATAAGGGGTGGGGCCTCAGCCAGGGTAGACTACTGT GAGGGGCAGGGCATCAGGCAGGAACAGTGCAACTGTGAGGGGCGGGGCCTCAGCGAGGGGGCATGGTTTC AGGCAGGAATGGCCCTCGGTGAGGGGAGGGGCCTCTCCAAGGGGCGGGGCCTGGTTTTCCCAGAGGTGGG ACCAAGTTGGTTTGAGGTTTAGCCCTCTAGGGAGGAGCTCAGTGTGAGACTCAGCCTGGGGGTGGGGCCT AGGCCTGCACTTGGGAAGGGGCAAGCCTGGTCCCGCCCCCAGCCCCCACACTTCCCACCACAGGCCCAGG AGAAATTAACAGAATCCAACCAGAAGCTGGGGCTGCTGCGGGAGGCTCTGGAGCGGAGACTTGGGGAGCT GCCCGCCGACCACCCCAAGGGGCGGCTGCTGCGAGAAGAGCTCGCTGCGGCCTCCTCCGCTGCCTTCAGC ACCCGCCTGGCCGGGCCCTTTCCCGCCACGCACTACAGCACCCTGTGCAAGCCCGCGCCGCTCACAGGTG GGTCTGAGACCCTACCCCACCCCTGCAGCCCTGGGCCTCCGACTCCTCTCATTTCCCCATTCCTGTGACC CCCGACTTCAATCTCCGCTCTCCCCAACCCTGGACTCCCATTCCACCACTGTCTCCTCCCCTCCTTTGCC CTCTGATTCTGGGCTCTTGCCCACCCCCCCCACACCTCAGTTTCTCCATCTCTCTTCACCTGGCCCAGTA TTTTTCTCCCAGCCCTTGTTCCCCAGCCCCACCTCGGCCTCACAACGCTCAGCCATGAGCCTCCTACCCG CCTGCTGCAGACCAGCCAGCCCCACCTTCCACAGACCCCTCAGCCATCTACCCCTCCAGACCAGCCCCAC CGTAGACCCCTAGCCCATCTTAGACCTCAGATTGTCCACCGAGTCCTCCCCTAGAACCCCTAGTCCTACC CTGTTCCTGCTTGCCTGGGCCTACGGCCTGTACCCTGAGCCTACGGCCTGTACCCTGAGCCTCTCTTCTG CCCCTAAACTCCCGCATCTGAGCCCCTCCTGGAAGGACTGCTTCTCTCATATTCTCCTATCCCAGCACGG ACATCCCGGCCTCATGCCCCATGCTCCATTCTGGTTGTCCCTCACTGGCTCCCACTTGTACCATGGCTGC GTCTGGATGTGTCCCCTCCCCGCTGTGGTCCCCTCCGCTCAGCCTGCCCCAGAAGTGGCCCCCTGCTGAG CTTTCCCCTCCTGCAGGGACCCTGGAGGTACGAGTGGTGGGCTGCAGAGACCTCCCAGAGACCATCCCGT GGAACCCTACCCCCTCAATGGGGGGACCTGGGACCCCAGACAGCCGCCCCCCCTTCCTGAGCCGCCCAGC CCGGGGCCTTTACAGCCGAAGCGGAAGCCTCAGTGGCCGGAGCAGCCTCAAAGCAGAAGCCGAGAACACC AGTGAGTGGGCATCGTGGGCCCTGAGAAACGAGGTGGCATTGGGGACCTGGAATGCCCCATATTTGTAAA CCTTTAAAAAATAAGCCAGGGGTCGGGTGTGGTGGCTCACACATGTAATCCCAGCACTTTGGGAAGCCAA GGTGGACGGATCACTTGAGGTCAGGAATTTGAGACCAGCCTGGCCAACATGGTGAAACACTGTCTCTACT TAAAAATACAACTTAGCTGGGCATGGTGGTGCACACCTGTAATCCCAGCTGTTTGGGAGGCTTAGGCAGG AGAATTACTTGAACCCGGGAGGTGGAAATTGCAGTGAGCCATGATCACGCCATTGCCCTCCAGCCTGGGT GACAGAGTGAGACTTTGCCTCAAAAGAGAACGAAAACAACAACAAAAACAAAAAAACAGGCCAGGTGCAG CAGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCTGAGACAGGAGGATCACTTGAGGCCAGGAGTTTGA GACCAGCCTGGGCAACATAGCAAGACCCTGTCTCTACAAAAAATAAAATGTAAAAATTAGCCAGATGTGG TGGCCCACACCTGTAGTCCTAGCTGTTCTAGAGGTGGGAGGATCACTTGAGCCCAGTGAGCTATCATTGA GCCATTTCACTCTAGCCTAGATGACAGAGAGACCCTGTCTCTAAATTAAAAAAAAAGAAAAAAAACTTCA AGTTTATTTAGATTAAAAAAAAGGCTGGGCGTGGTGGCTCACGCCTGTAATCCCAGCACTTGGGGAGGCC GAGGCGGGTGGATCACGAGGTCAGGAGTTCAAGACCAGCCTGGCCAGCATGGTGAAACCCCATCTCTACA AAAAATACAAAAAAATTAGCCAGGCGTGGCGGCGCGTGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGC AGAGAATTGCTTGAACCCAGGAGGCGGAGGTTGCAGTGAGCCGCGATTGTGCCACCGTACTCCAGCCTGT GCAACAGAGCAAGACTCCATCTCAAAATAATAATAATAATAATAAATAAATAAAACAAATTTAAAAAGAA AGGAAAACCAAACAAGAAACCAATATATCATATTCATTAGGATGACTAATACTATTTTAAAAACCCAACA AAACAAACAGAAAATAAGTGTTGGTGAGGATGTGGAGAGAAATCAGAACCTTTGTGCACTGTTGGTGGGA ATGTAAAATGGTGCAGCCCTATGGAAAATATATTGGCATGGCCGGGTGCAGTGGCTCACACCTGTAATCC CAGCACTTTGGGAGGCTGAGGGGGCCAGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCTATCATG GCAAAACCCCGTCTCTACTAAAAATACAAAAATTAGCTGGGCATGGTGGTGTGTGTCTGTAATCCCAGCT ACTCAGAAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGCAGAAGTTGCAGTGAGCTTAGATCGAGC CACTGCACTCCAGCCTGGGCAACAGAGCGAGACTCTGTCTGAAAGAAAGAGAGAGAGAGGGAGGGAGGGA GGGAGGAAGGAATATTGGCAGTTCCTGAAACAAGTAAAAACAGAGTAAGCAGTCCAGGCGCAATGGCTCA CACCTGTAATTCCACCACTTTGGGAGGTCAAGGTAGGTGGATCACCTGAGGTCAGAAGTTCAAGACCAGC CTGGCCATCATGGTGAAACCCCATTTCTACTAAAAATACAAAAGTTAACCGGGCTTGGTGGTGGTGCACG CCTGTAGTCCCAGCTACTCTGGAGGCTGAGGCAGGAGAATTGCTTGAATCCGGGAGGCAGAGGTTGGAGT GAGCAGAGATCATGCTACTGCACTCCAGCCTGGGTGACAGAATGAGACTCCATCTCAAAACAAACAAACA AACAAAAAAACAAGAGTAACCATATGATCCAAAGCTACTTCTGGGCATATCCCCAAAAGAATTAAAAACA GGGCCTCGGACATTCCATAATGCATACATATTTCAAAACAACATGTTGTGCATGATAAATATATATAATT TTTATTTGTCAGTTTTAAAAATAGTGATAGAAAAATATTTAAAAAAAAAAAAAAGGGTCTCAGAGATATG TATACCTGTGTTCATAGCAGCATTATGAAAGCCAAAAATGGAAGCAACCCAGATCCACCAATAGATGAAT GGGTAAACAAAACGTGGGCCAGCCATGCAATGGAACATTGCTCAGATTTAAAAAGGAAAGAAATCCTGCC AGGCGCAGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCACTTGAGGTCAG GGGTTCGAGACCAGCCTGGCCAACATGGTGAAACCCCATCTCTATTAAAAATACAAAAATTAGCCGGGTG TGGTGGCACATGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGTAGGAAAACCGCTTGAGCCCAGGAGGC AGGCGTTGCAGTCAGCCAAGATCATGCCACCGCACTCCTGCCTGGGTGACAGAGTGAAACACTGTCTCAA AAAAAAAAAAAAAAAAAAGGAAAGGAATCCTGTCTTATCCTGCAACACGGATGAATCTTGAGGACATTAG TCTAAGTGAAATAAGCCAGTCCCCAAAAGACAAATATTGTATGATTCCAGTTATATGAGGTTCCTAGAGT AGTTAGATTCATAGAGACAGAAAGTAGAATGATGGATGCCAGGGAGTAGAGGGAGGGGGAATGGGGAGTT TATTATTTAATGTGGACAGAGTTTCAGTTTTGTAAGGTGAAAGTTCTGGAGATGGATGGTGGTAATGGTT GCACAGCAATGTGAATGTACTTAATGCCACTGAACTGGATGGACACTTTAAAGTGATTATGATGGTAAAT TTTATGTTACATGTATTTTACCATAATTTTTTTTTTCTTGAGACAGATTCTCCTCTGCTGCCCAGGCTGG AGTGCAGTGGCACCGTCTCAGCTCACTGCAACCTCTGCCTCCTCGGTTTGAGCGATTCTCTTGCCTCAGC CAACCCAAATAGCTGGTGGGATTACAGGCGTGCGCCACCACACCCGGCTAATTTTTGTATTTTTATGGAG ATGGGGTTTCACCATGTTGGCCATAATTTTTTTAAAAGAAAATTTGATTCGTAATCTCATGGCAAAAAAG GAAAAAGAAAGAAAATTAATACGTATGTACAAAAAAAAAAGGGAGTGTGGAGAAGAGTAACAGGAGAGCA GACACCCATATTACCACCACCTGCGTTAGGAAATAGAATATGGCAGCCAGGTGCCACGGCTCATGCCTGG AATCCCAGCATTTTGGTATTTGTAGGAGGATCACTTGAACCCAGGAGTTCAAGACCAGCCTGGGCAACAT AGCAAGACCTTGTCTTTACAAATAATTTAAAAATTGGGGCATATGGCCAGGTGTGGTGGCTCACGCCTGT AATCCCAGCACTTTGGGAGGCCGAAGCGGGTGGATCACAAGGTCAGGAGATCGAGACCATCCTGGCTAAC ACAGTGAAACCCCAACTCTACTAAAAATACAAACAATTAGCCAGGCGTGGTGGTGGGCGCCTGTAGTCCC AGCTACTCGGGAGGCTGAGGCAGGAGAGTGGCATGAACCTGGGAGGCAGAGCTTGCAGTGAGCCGAGATC GCGCCACTGCACTCCAGCCTGGGTGACAGAGCAAGACTCTGTCTCAAAAAAAAAAAAAATTGGGGGTACA TGTCATCAGGCCCTCCTGAATCTGTGTCACAGAAAAAAAAACTAAAGGGAAAAAAAGAGAAGACAAGCCA ACCAAAAATTAACCAGGCGTGGGCATGGTGGCTTGTGCCTGCGGTCCCAGCTACTTGGGAGGCTGAAGTG GGAGGATTGCTTGAGCGCAGGAGGTCAAGGCTACAGTGAGCTGTGATTGCACCACTGCATTCCAGCCTGG GCAACTGAGCGAGACCCCATCTTAAAAAAAAAAAAAAAGGAAAAGAAATAGAATATTTCCAGCTCTCCAG AAGCCCCCTCTTGTCTCCTCCACAATTCCATCTCCTTCCTCTGCCATAGAGGTGGCTACTCTCCCGACTT TTATCATTTCCTTGCTATAATTTGTAGTTGTAGAACCCCATGTTTGCATCCCCAAAAACTTTTGTTTAAT TTTGCCTGGTATTAGAACTTTATATTGACAGGCTCATACAGACTATTCTATCACATGGCTTCTTTCATTC AACATTGTTTAGGGGCTAGGCATAGTGGCTCATGCCTGTAATCCCAGCACTTTGAGAGGCCGAGGTGGAG GGATTGCTTGAGCCAAGGAATTTGAACCCAGCCTGGGCAACATGGTGAAACCCCACCCTACAAAAAAATG CAAAAAACAAAACCAAACTAAAAAAAGCATTGTTTTGGTAGACTCATCCATTTTGTTGTGACAAGCTATA GTTAATTCATATTTATTCCTGTTTAGTAATCCATTATGTTAGACTGAGCCATATCGAATTGCCTCTTTCT GAAAGCAAAAAAATAGTTAAATATCAGCAATTTCGTACTTCAGCTACTAAGATGGTATAGCAGTTTTAAA ATATTAATTCTCCTGTTAATGGACTGTGGGATGCCTCTATTTTGGACTGTTACATACACTTTATATAAAT GCATCTCCTGATGTATACCCACATGCATTTGGCTAGGGTAAATCCTCAGGAGTGCCTGGGCGCGGTGGCT CACGCCTGTAATCCCAGCACTTTGAGAAGCCAAGACCAGTGATCACTTGAGGTCAGGAGTTCAAGACCAT CCTGGCCAACGTGGCAAAACCCCATCTCTACTAAAAACACAAAAATTAGCTGGGCATGGTGGTGTGCGCC TGTAGTCTGAGCTACTTTGGAAGCTGAGGCACGAGAATTGTTTGAACCCAGAAGGTGGAAGTTGCAGTGA GCCGAGATTGTGCCACTGCACTCCATCCTGGGTGACAGAGAGAGACTCTGGCTCAAAAAATAAATGAATA AATAAATCCTTAGGAGTATGTGGCTGGGACTTCCATGTAGAATAAAATTGAATTTGGATCCCTGCCTCAC ATCACACCATGTAAAAAAATCAACTGGATTAAAGGCTTCAATGTCAAATGCAAAACTTTACAGTGGGAGA AAAGTTATGGAGGGGAGGATTCATTTTAAAAAGATAGCAGACAGCTAGGCCTGGTGGCTCATGCCTGTAA TCCCAGATACTTGGGAGGCTGAGGCAGGAGAATATCACTTGAGGCCAGGAGTTTGAGACCAGCCTGGGCA ACATAACAAGACTCATCTCTACTGAAAAAAAAAAAAAAAAAGAAAAAGATAATAGACATGCCCCTTTCTG CCAGGATTTTCTTTCTTTTTCTTTTTTTTTTTTCTTTTTTTTTTTTTTTGAGATGGAGCTTCACTCTTGT TGCCCAGGCTGGAGTGCAGTGGCGTGATCTCGGCTCACTGCAACCTCTGCCTCCTGGGTTCAAGGGATTC TCCTGCCTCAGCCTCCCGAGTAACTGGGATTACAGGCATGTGCAACCACGCCTGGGTAATTTTTTATTTT TAGTAGACATGGGGTTTCACCATGTTGGTCAGGCTGGTCTCAAACTTCTGACCTCAGGTGATCCACCTGC CTCAGCCTCCGAAAGTGTTGAGATTACAGGCATGAGCCACTGTGCCTGGCCGTTTTTATTTTCTCTTCTC TTCTCTTCTCTCTTTTCGACCGAGTCTTGCTGTGTCACGCAGGCTGGAGCGCAGTAGCACGATCTTGGCT CACTACAACCTCTGCCTCCTGGGTTCAAGTGATTCTCCTTCCTCAGCCTCCCGAGTAGCTGGCATTACAG GCGCGTGCCACCACGCCCAGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCGCTATGATGGCCAGG CTGGTCTTGAACTCCTGGCCTCAAGTGATCGCCTGCCTCAACCTCCTAAAGTGCCGGGATTACAGGCATG AGCAACCTTGTCTGGCTACTGCCAGCATTTTCTGACTGGGCCCTCTCTCCCATTTCAGGTGAAGTCAGCA CTGTGCTTAAGCTGGATAACACAGTGGTGGGGCAGACGTCTTGGAAGCCATGTGGCCCCAATGCCTGGGA CCAGAGCTTCACTCTGGAGCTGGAAAGGGTGAGCTGCGTTGGAGGACAGCAGGGCCTAGAGGAGGAGGGG TTCCATGCCTCTGGCACCCTGAGTGATGGCCCTCTTCCTCTCCCTCCAGGCACGGGAACTGGAGTTGGCT GTGTTCTGGCGGGACCAGCGGGGCCTGTGTGCCCTCAAATTCCTGAAGTTGGAGGATTTCTTGGACAATG AGAGGCATGAGGTGCAGCTGGACATGGAACCCCAGGGCTGCCTGGTGGCTGAGGTATAGCCCACACCTGA CCCTGAGAAAATGCTTCTTCTCCCTCACTGCCCCATTCCCAGTTTCCTAGAAGGGGAAAATATGTTTTAG GTCTGGCTCTTCCAGAAGGGGAAGATAAGTTTTAAGTCAGGCTTTTCTAGAAGAGGAAAATAGATTTTAG ATCCAGCTCTTCTAGAAACGGAAGATATGTTTTAACTCTGCCTTTTCTAGAAGGAGAAGATACGTTTTAG GTCAGGCTCTTCCAGAAGGGGAAGAGACGTTTTAGGTCTGCTTTTTTCTAGAAGGGAAAGATATGTTTTA GATCAGGCTCTTCTAGAAAGGGAAGATAGGCTTTTGATCTGCCTGTTCTAGGCTGGGCGTGGTGGCTCAT GCCTGTAATCCCAGCACTTCGGAAGGCTGAGGCAGGAGGATCACCTGAGGTCAGGGAGACCAGCCTGGGC AACATGGTAAAACCGCGTCTCAACTAAAAGTACAAAATTAGCTGGGCGTCGTGGCACATGCCTTTAGTCC CAGCTACTTGGGAGGCTGAGACAGGAGAATCGCTTGAACCCAGGAGGCGGAGGCTGCAGTGAGCTGAGAT CCCACCACTGCACTCCAGCCTGGGCGACAGAGTGAGACTCTGTCGCCCAGGAGTCTCACAAAAAAAAAAA AGATCTGCTTGTTCTAGAAGGGGAAGATACATTTTAGATCAGGCTCTTTTAGAAGCATAAGATATGTTTT AGATATGGTTTCTCTTAATACAGAAAGATAGTTTTAGATCAGGCTCTTTCAGAAGTGGCAGGTATGTTTT AGACCCGTGTATTCTAGAAGGGGAAGATACATTTTAGATCTGTCTCTGAACCTTGATAGAAAAGTACACC TTGGCCAGGTGTGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGTGGATCACTTGA GGCCAGGAGTTCCAGACTAGCCTGGCCAACATGGTGAAACCCCATCTCTATTAAAAATACAAAAATTAGC TGGGCATGATAGTGGGTACCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCA GGAGACAGAGGTTGCAGTGAGCTGAGATCACGCCATTGCACTCCAGCCTGGGCAACAGAGTGAGACTCTT GTCTCAAAAAAAAAAAAAAAAGAAGAAGAAGAAGAAGAAAAGCACTTCTAATTAGCCACATCAGTGATAG GACCTTAGCTGGGATTGGTTTTGTTCTGAGGCAAGATACTTAAAAAAAAAAAAAAAGAAGAAGAAGAAGC TGATTTCCAAATTTAGAAATGTTTAAAGAAAAAAGGAAATAAATTATAAAATTTCTTCCAACCAGGAAAG AGATACAAAACCTGGCAACATATCGTGGTGATTGCTACCAGAGCCACAGTCAAGAGAAAGTGATTCCTTC CACAGCTGTGTGAGGGTGAAGGTCTGAATTGAGGTGGCCTACCCTTGGCACTGTTGACATCTGGGGCCAC ATCATCCTCTGTGGTGGGGCTGTCCTGCATACTAGAGGATGTAGCACCTCTCCCCACTGCTTACAGGATG TCAGTAGCACCACCTCCCCCTGAGTTTTGACAGCCCAGAGGTCTCCAGACACTGTCAAGTGCTCCCTGGC CGGGAACCCCTGGTCTAAATGACATTTCTAGCTGAGTTCTCATAGTATAAGCCAGGCTCTGTAGCGAGTA CTTTGGCGACGTGAACTCATTAATTCTCACAACCAACCAACAAAAGAGGGACTGTTATTACTCAAATTTG ACAGAGGAGGAAACTGGGGCACAGAGAAGGGGCACTTGACCCCTCATTTAGCCAAATTATCCTAAAAAAC TCTTTTAATCTTCCGCTAACCTATATGTGTACCCCATTTTACATATATATATGATAGATTACCTATATAT GTATACACACACATATTATCTATTATTTACCCACCTACGTGTCCATCCATCCATTTTGTCTGTCTATGCA TTCATCCATCCATCTTTTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTCGCTGTCTCCCAGGCTGGAGTG CAGTGGTGCGATCTTGGCTCACTGCAACCTCTGCTTCCCGGGTTCATGCCATTCTCCTGCCTCAGCCTCC CGAGTAGCTGGGACTACAGGCACCCGCTACCACGCCCGGATAATTTTTTGTATTTTTAGTAGAGACGGGG TTTCACCCACCGTGTTAGCCAGGATGGTCTCCATCTCCTGACCTCGTGATCTGCCCGCCTTGGCCTCCCA AAGTGCTGGGATTACCGGCGTGAGCCACCGCGCCCGGCCCAGCCATCTTATCAATGCATCCTCTATCCAT TGATAGATACACCTATATTATCTGTCTTATCTATGTATCCATCTATATTAGGTATCTATATCATCTATTT ATCTAATCCATCTATCCATTTATCTATCTCTATCTATATATTATCTATCAACCAATCTATTTTTCCATGC ATCCGTCTCTATTATCTGTCAGTCATCTTATCCATCAATCTTATGTATGCATCATCCATCCATCTATCCA TCCCTGTATATTTCTCTGTATATATATCTACCCATTCCTCTCTCTATCTCTATCTATCCCTCTCTATATC TATCTGTGCCTCTGTTTTTCTCTATATAGCTATATCTATCTATCCATCCATCTATATTATCTATCAACTA ATCTATCTTTCCGTCTACCCATCTGTCTATATTATCTATCCATCTATATTATCTATCTATCATCTTATCC ATCCATCCATTTATCTTATCTATGCTCATCCCTCCATCCATCCATCTCTGTATATTCCTCTATCTCTATT TATATCCACCCATTCCTGTCTCTGTCTCTATCTATCCCTCTCTGTATCTATCTGTGTCTCTCTCTCTTTT TCTCTCGATAGCTGTATCTATCTATCCATCCATCTATCCATGCATCCTTCTCTTTCTATGAATCCCTTTC TCTATCAGTCCCTCTCTCTTTCTCTATCTGTAACTACCCTTCCGTCCATGCCCCTCTCTATCTACCTGCG TCTATATCTGTCTCTTTCTGTGTCTATTTATCCATCTCTCTATATCCATATCCCTAAGCAGAGGTTCTCC CCTGGTCTGACCATCAAGCACCAGTGAAAGAAAGGGGCGGGGCCAGGCACAGTGGCTCACACCTGTAATC CCAGCACTTTGGGAGGCTGAGGCGGGCAGATCACTAAGTCAGGAGTTCGAGACTAGCCTGGTCAACATGG TGAAACCCCGTCTCTACTGAAAATAGAAAAATTAGCCGGGTGTGGTAGCAGGCGCCTGTAATCCCAGCTA CGCGGGAGGCTGAGGCAGGAGAATCAGTTGAACCTGGGAGATGAAGGTTGCAGTGAGCCGAGATCGCATC ATTGCACTCCAGCCTGGGCAACAACAGCGAAACTCTGTCTCAAAAAAAAAAAAAAGAAAGAAAGAAAGGG GCGTGGAGAAGAGCTGACTCCAGATGGCAGAGGTTTAAAATTGTTCTCCCATTCAGAACACAGCCCAAAC CAAATGGAAAGTGATGGTGGGTGGCCTGGGGGACACATTCTAAAGCGTTTCTCCTTGCCTTCAAGGTCTC TCTGTGGCATTCTATTTTGTTTTTATGCCTATACAGAAGCATTCTTCCATAGAACTTTTCTGCAGCTCTG GCCGGGCGCTGTGGCTCACGCCTGTAATCCCAATACTTCGGGAGGCTGAGGCGGATGGATCATTTGAGGT CAGGAGTTTGAGACCAGCCTGGCCAACATGGTGAAACCCTGTCTTTACTAAAAATACAAAAATTCGGCTG GGTGCGGTGGCTCACGCCTGTCATCCCAGCACTTTGGGAGGGTAGGCAGGCAGATCACCTGAGGTCAGGA GTTCAAGACCAGCCTGGCCAACGTGGAAAAACCTAGTCTCTACTAAAAATACAAAAATCAGCCAGGTGTG GTGGCGCACGCCTGTAATCCCAGTTACTTGGGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAGGCGG AGGTTGTAGTGAGCCAAGATCGCACCACTGTACTCCAGCCTGGGCAACAGAGTGAGACTGTGTCTCAAAA AAAAAAAAAAAGAAATTAGCCGGGCTTGGTGGTGGGTGCCTGTAATCCCAGCTGCTCGGGAGACTGAGGC AGGAGAATCTCTAGAGCCTGGGAGGTGGAGGTTGTGGTGAGCCCAGATTGCGCCACTGCACTCCAGCCTG GGCAACAGAGTCTCAAAGAAAAAAGGAACTTTCTGCAGCTCTGTTGTCGATGCACCCACAGTAGCTGAGT TCTGTTGTAGATGGAAATGTTCTCTATCTGAAGTGTGACCAGTGTGACCAGGGAACCAAAGTTTTAATTT CGCTGACATTTTCACTAATTTAAATCGCCACATGTGACAACCATACCAGACACTGCAGTTCTGTGACTTC AGCACCTTCTAGAAGTTGTATTGGAGTTGGGAGAATTCAACTTGACAGGTGGCTTCCATAGATGGGTGGG CACCAGCATTGCCTGGGGGCTTGTTGAAATACTGAGTGCTTTAGGGCCGGGCACGGTGGCTCGCGCCTGT AATCCCAGCACTTTGGGAGGCCAAAGTGGGCAGATCGCTTGAGCCCAGGAGTTCAGGACCAGCCTGGCCA ACATGGTGAAACTCCGTCTCTACAAAAATACAACAATTTGCCAGGCATGGGGGTGCGTGCCTGTAGTCCC AGCTACTCAGGAGGCTGAGGTGGGAGGATCTCTTGAGCCCGGGAGGTGGAGGCTGCAGTGAGCCGAGATC GGACTACTCATATGTGCATATATATATGTGTGTATATATATATATGTGTGTGTGTATATATATATATATA TAGAGAGAGAGAGAGAGCATGCGCGCGCTTCCTCCACTCCATGTTTCTGGCTCAGTAGGTCAAACCTGCG TTTCTAGAAAGTTCCCAGGTGTTGCTGCTACTGCAGGTCTGGGGTCTGGGAGCACATGTGGGGAATGGGG TGTGGGATGGCGTGGCGTCCGTTTGCAGTCGCTGTCTGTCAGTCTTGTTGGGTCAGATGCTCTCCCCACC TCTAGAAAGGGACCCGGTTGTTTGCTTCTTGCTTTTCCAAGACGTCCCTTCAGGAGGGGAGCCATGGGTT GCACCGATGACCTCTTCATTGTCACCTGGTACTCGGGTTGAATCTGATGCCACGTGACCAGAACCCCACT TGGGCGCGCACACCTGTGCTCCCAGGGGCTTCCTTACCAAGCTGTCTGCCTGCAGGTGGGCAGAGGGTCC TCACATTTTGGTCCCTTCCCCCAGGTCACCTTCCGCAACCCTGTCATTGAGAGGATTCCTCGGCTCCGAC GGCAGAAGAAAATTTTCTCCAAGCAGCAAGGTGAGAGGGTGCTCCAGGCTTCCTGGGGGAGAGGCCAGGG GTCCTGGGAGTGTCATGGAGGGTGACGCCTGCCCCGTCCCCCCAGGGAAGGCGTTCCAGCGTGCTAGGCA GATGAACATCGATGTCGCCACGTGGGTGCGGCTGCTCCGGAGGCTCATCCCCAATGCCACGGGCACAGGC ACCTTTAGCCCTGGGGCTTCTCCAGGATCCGAGGCCCGGACCACGGGGTAAGGAAGGAGGGCCCCATGGT CCCGGCTGCCCCTTGAAGCCTGCGAGGGTCCTGGGTCCCAGACACACCCTCCTCTCGTCTGCTGCAGTGA CATATCGGTGGAGAAGCTGAACCTCGGCACTGACTCGGACAGCTCACCTCAGAAGAGCTCGCGGGATCCT CCTTCCAGCCCATCGAGCCTGGTGAGGGTCCCCCCTTCTATCCCCGTAGGCCTGGCCTGGGCAGCGTCAG GGGTCCTGCTCCAGGCTCAGAGACCACTAGGAACTTCCCTGGAGCCACGCAGCATGTCTGTGGCAGAACC AGGGCCCAGATCTCTATGCTGGTTAAAACGTGTGCCCAGATCCCCATCCTGGTTAAAAAACTGCTCATGC CTATAATCTCAGCACTTCTGGGAGGCTGACATGGGAGGATTGCTGGAGCCCAGGAGTTTGAGACCAGCCT GGGCAACACAGTGAGCCACTGTGAGCCATGATCCTGCCACTGCACTCCAGCCTGGGCAACATAGCGAAAT ACTATCTCAAAAAACAAAACAGGCTGGGCACAGTGGCTCACACCTGGAATCCCAGCACTTTGGGAGGCTG AGGCGGGTGGATCACTTGAGGCCAGGAGTTCAAGACCAGCCTGGCCAACACAATGAAACCCCGTCTCTAA TAAAAATACAAGAATTAGCCGGGTACGGTGGTGGGCACCTGTAATCCCAGCTACCCGGGCAACTGGGGCA GGAGGATCAGTTGAACCTGAGAGGCGGAGGTTGCAGTAAGCCAAGATCATACCAATTGCGCTCCAGCCTG GGCGACAGAGCGACTCCATCTCAAAAAATAAAAATAAATAAAACTGTGAGCTCAGCGGCTGGACCCCCTG GGTTCCCACCCCTGCCGTGCCACCTCTTGGCTCTGCGCTTCACCTCTGTGCCTCAGTGTACCACTTTGCA AAACGAGCATATTTAAAACTCATGTCAATGATAGAATGATCGAGAGAGTGCTGTTCTCTAGGCAGAGGTT ACCGCAAGCTGGGAGCCACAAGGGGACCTGCCGGGTGATGGAAATGTTCCTTATCTTGATCTCGGTCAGA GGTCAGCACGCGTTTTCCAGAAAGGGCCAGAGAGTCAATATTTTTGGCTTTGTGGGCTAGACAGTCCCTG TCTGCTTTGTAGTTTGAAAGCAGCCACAGACGATATATGTACACTGTAAGCGTGTCTCTATTCCAGTAAA ACCTTATTGGTAGTACACGCGGAAGTTTGAACATTGTAGAACTTTCATGGGCAATGAAATATTATTCCTT TTTTTGTTTTTTTTTATTCCCCCAACGATTTAAAAATGTAAAAATCAGTTTACCTGTGGTCCCAGCTACT TGGGAGGCCGAGGCAGGAGGATGACTTGAGCCCAGGAGTTGGAGTCTGGCCTGAACAACATGGCAAAACT CCATCTCTTTTTTTTTTTTTTTTGAGATGGAGTCTCACTCTGTTGCCCAGGCTGGAGTGCAGTGGCGTGA TCTAGGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGGGATTCTCCTGCCTCAACCACCCGAGTAGCTGG GACTACAGGTGTGTGCCCACCACACCCAGCTAATTTTTGTATTTTTAATAGAGACGGGGTTTCACCTCGT TGGCCAGGCTGGTCTTGAACTCCTGACCTCAGATGATCTGCCCACCTCAGCCTCCCAAAGTGCTGGGATT ATAGGTGTGAGTCACCATGCCCGGCCACTGCATCTCTTAAAAAAAAAAAAAATAGTGAAAGCCATTCTTA GCTCTTACAAACTATAAAAACAGGCTGGCCCACCAGCCAGCATTTGCCAACTCCTAGGCTGGCTGATGGT TTCCTGGGTGGATGCATATGTAACCTGTTCCTCTTGCCCACCTCACTGAATGCATTTTATTTATTTATTT ATTTTGAGACAGAGTCTCACTCTGTCGCCCAGAATGGGCGTTGGAATGCAGTGGCGTGATCTCAGCTCAC TCCAATCTCCGCCTCTCAGGTTCAAAGATGCCCATGCCTCAGCCTCCCTAATAGCTGGGACTACAGGCAT GTGCCATCATGCCCAACTAATTTTTGGTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCT TGAACTCCTGACCTCAAGTGTTCTCCCCTCTGCAGCCTCCCAAATTGCTGAGATACAGGTATGAGCTACT GCACCCAGCCTGAATGCATTTTATCTTTTATCTTTTTTTTTTGAAACGGGGTCTCGCTCTGCCATCCAGG GTGGAGTGCAGTGGCGCAGTCATGGCTCGCTGCAGCCTCGACCTCCTGAGCTCAGGTGATCCTCTCACTT CAGCCTCCCAAGTAACTGGGACTACAGGCGTGCACCACCACACCTGGCTAATTTTTTATAGATCTAATTT TTTAGAAAGTAGAAGTAATGGGTTGGGCATGGTGGCTCACGCCTGTAATCCCAGCACTTTGGAGTCAAGA GATCAAGACTATCCTGGCTAACATGGTGAAATCCCATCTCTACTAAAAATACAAAAATTAGCCGGGCGTG GTGGCGCACGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTGGAATCTGGGAGGCGG AGGTTGCAGTGAGCTGAGATCACACCACTGTACCCCAGCCTGGGCGACAGAGTGAGACTCAGTCTCAAAA ATAAAAAAAATAATAATAAAAAATGGACATTGTCAAGCCAGGCATGATGGCTTGCACTTGTAGTCCCAGC TACTCAGGAAGCTGAACGAAGAAGATCGCTTGAGGCCAGAAGTTTGAGACCAGCCTGAGGAACAGAACAA GACCCCATCTCTACAAAAATTAGGCCGGGCGCGGTGGCTGACGCCTGTAATCCCAGCACTTTGGGAGGCT GAGGCAGGTGGATCACCTCAGGTCGGGAGTTGAAGACCACCCTGACCAACATGGAGAAACCCCATCTCTA CTAAAAATATAAAAAATTAGCCGGGCGTAGTGGTGCATGCCTGTAATCCCAGCTGTTTGGGAGGCTGAGG TAGGAGAATCACTTGAATCCGGGAGGCGGAGGTTGCAGTGAGCGAAGATCACACCATTGTACTCCAGCCT GGGCAACAAGAGTGAAACTCCATCTCAAAAAAAAAAAAAATGAGCTGGACGTGGTGGTGCATGCCTTTAG TCCCAGCTACTCAGGAGGCGGAGGTAGAGTTGGAGGCTGCACTGAGCTATGACTGCGCCCCTGCACTCCA TCCTGGAAGACAGAGCAAGACCCTGTCTCTAAAAAAAAAAATTCAGGTTGGGCATGGTGGCTCACGCCTG TAATCCTGGCACTTTGGGAGGCCGAGGCGGGTGGATCACCTGAGATCAGGAGTTCCAGACCAGCCTGGCC AACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCCAGCCATGGTGGTGCAGGCGTGTGGCT GGAGGAGAGTGAGTGAGGGGCTGCGTGGGAGGAGAGGTGAGGACAGAGAGGTCGGGGGCAGATCTTGCAG GGCCTCGGAGGCTGCTGTGGTTATGAGGGCATCTCTGACTCCCCTTACTCTGGCCTCCTCTCTCCGCCAC AGAGCTCCCCCATCCAGGAATCCACTGCTCCCGAGCTGCCTTCGGAGACCCAGGAGACCCCAGGCCCCGC CCTGTGCAGGTGACACCACTCCCTGGCCCCCTGTCCACCACCCCTGCCCGCTGTCCTTGTTCTCACCAGT GGCCTCTCTCCACAGCCCTCTGAGGAAGTCACCTCTGACCCTCGAAGATTTCAAGTTCCTGGCGGTGCTG GGCCGGGGTCATTTTGGGAAGGTGAGGTGGAGGGCAGGGAATTGGGAGACCCCCCAGGTCCCTGGCTGGC CGCTAAAACCACCCCTGCCCACTGTGGTTCCAGGTGCTCCTCTCCGAATTCCGGCCCAGTGGGGAGCTGT TCGCCATCAAGGCTCTGAAGAAAGGGGACATTGTGGCCCGAGACGAGGTGGAGAGGTGGGGACCTGCCGT GGTCCTCTGGGGACCTCTTTCTTCTCTTTTGGGAAATGACAGAGCAGTTCTCTCCTTGGAGCTACAGGGA GAGTGACTCATAGTAGTCACTAACGCCAGGCACAGTGGCTCTTACCTGTAATCCCAGCACTCTGGGAGGC CGAGGCAGGTGGATCACTTGGGCTCAGAATTTCAAGACCAGGCTGGGCAACATGGTGACACCCCCATCTT TACAAAAAATACAAAATAATTAGCTGGGTGTGGTGGCACATGCTTGTAGCCCCAGCTACTCATGAGGCTG AGATAGGAGGATCGCCTGAGCCCAGTAGGTCAAGGTTGCAGTGAGCTGAGATCGCGCCACTGCACTCCAG CCTGGGCAACACAGTGAGACCCTGTCTCAAAACAAAAAGTCACTAATACCTACTAGCCTAATACCAAGAT AATAATAGCTCTTAGGAAAGTTATTCATTTGTTCCTCCATGTAGCCCTATAAGATAAATACTGATGGCAC AGAGAGGTTCAGCAATTTACCCAAGGTCACACAGCCAGTAAGCAGCAGGTCCAGGATTCAAAGCTAGAGA CTCAGGCTCTGAAGCCTGTGCCCTTTGTGGTGCCACCATACTGCCTCTGCTTTAGGGTCAGGTTCCTGGG TTCAAATCTCAATTCTGCAGCATGGGCTTGGAGATCCTGGGGAGGTCACTTCTCCCTTCAGAACCTCAGC TTCTTGGCTGGGCATGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGGGCAGATCATC TGAGGTCAGGACATCGAGACCAGTGTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATC AGCCAGGCATGGTGGCGGGTGCCTGTAGTCCCACCTACTTGGGAGGCTGAGGCAGGAGTATCGCTTGAAC CCAGGAGGCGGAGGTTGCAGTGAGCCAAGATCGCACCACTGCACTCCAGCCTGACTCTGTCTCAAAAAAA AAAAAAAAAAAAAAAAAGAACCCCTCTTGTTGTGGAGAAGCAGAATGCTATTGCCTTCCACACATGGTTG TCAGGTGCTCTCTACACAGTGCCTAACCCCTCTAAACATTCGGTACAGGCACTGAGATTGTGCCTGGTCT TCCCAGCATCCTTTTGATAATCAGGAACCCAACTGAGAAAGACTGAAACAAGTAAAGAAATTTATTGGTC TGGATCTGAAAAGTCCAGGAGTGTGCTACCTTCAGGCATGGCTGTATCCAGGTGCTGAGATGACGTTTCT CAGTTCTGCTTCCCTCTGTATGGGCTTTGGTTGCCATCTGGGAGTCTGGAGTAAGTGGCGGCCATGGTCT CTGACTTCTATCCCCCACCCCTCCCCAGCCTGATGTGTGAGAAGCGGATATTGGCGGCAGTGACCAGTGC GGGACACCCCTTCCTGGTGAACCTCTTCGGCTGTTTCCAGACACCGGAGCACGTGTGCTTCGTGATGGAG TACTCGGCCGGTGGGGACCTGATGCTGCACATCCACAGCGACGTGTTCTCTGAGCCCCGTGCCATGTGAG CCTGGACCCCAGCCCGGGCCCCTGCCTCCCCTACAGCATCTGACACTTAGTCCCCCCGAGAGGCTGGCAG CCTGCTTCTCACCCCTCCACCCTCAGGCCTTGCTTCCCTCAGCCTCCCAGAGCTTTGGGGAGACTGGGGG GCTTTTGAGGATGTGGAAGCCAGGCTTATGTGACCCTCCCTCCTTGCAGGGTGGCCCCACCCCTCTCAGC AGCCTCTCTCTCTCTGCAGCTTTTATTCCGCCTGCGTGGTGCTGGGCCTACAGTTTCTTCACGAACACAA GATCGTCTACAGGTGTGTGCGTGTGTGCATGCATGTGCACACTGCCCGTTGTGGGGACAGGACCCAGACC CCCGCTCATCCCTCTTTCCACCCCTCCAACCCCCAACAGGGACCTGAAGTTGGACAATTTGCTCCTGGAC ACCGAGGGCTACGTCAAGATCGCAGACTTTGGCCTCTGCAAGGAGGGTGAGGGGCTGGCCTCTGGATTAG ACAAAGGAGGGGGAAGGAATGGGGTCCCTAACCCTATTCGGGGTGCCCCCCACCCTGACCCTGGGACAGG GCTGGCTGTGTGGACAACCCCACATTGGGCTGAGTGACTCCTCTGGCCCCCATAACCTCACATGGCCTTG CTGTCCCCAGGGATGGGCTATGGGGACCGGACCAGCACATTCTGTGGGACCCCGGAGTTCCTGGCCCCTG AGGTGCTGACGGACACGTCGTACACGCGAGCTGTGGACTGGTGGGGACTGGGTGTGCTGCTCTACGAGAT GCTGGTTGGCGAGGTGAGACCCCGCCCCTGTGTGTCTCGGATCTCATTGGAACCTGCGCGTGCCCAGGGT GGGATCCAAGTCTGCCTCCACCATGTGTTGTGTGATTGAGGGCTGCTGGCTCTGCTTCCCTGGCCTCAGT TTCCACATCTATAAAATGGGGCATTTCCCTGCCCAAGTAAGCCAGCACCCAAGAGCTGCAGCAGAGTGTG GGGCTCAGGCCGGGCTGGGTTTGGAGCAGCCAGAGGAGGGGCCTCGTTCACCCCGGGCCTCCCTCTCCCC AGTCCCCATTCCCAGGGGATGATGAGGAGGAGGTCTTCGACAGCATCGTCAACGACGAGGTTCGCTACCC CCGCTTCCTGTCGGCCGAAGCCATCGGCATCATGAGAAGGGTGAGGACCCCCGACGTGGGGCGGGCCTGG GGAGGGGCAGTGGGGCCCAGGAGGGGACAGATCCTGACACAGTGCTCCTTCCTCCAAGCTGCTTCGGAGG AACCCAGAGCGGAGGCTGGGATCTAGCGAGAGAGATGCAGAAGATGTGAAGAAACAGCCCTTCTTCAGGG TGAGATTCCCCACAAGGACCTCAGTGACCCCGGCCCTCCCCCAGGGCCGATTCATCACCCCACAGCAGAC GGCCCCCATGCCTAGCCGCTTTGCCTCAAGGGCCTCGTTGCGCCTCAAGGGCCTCGTTGCACCTCCAGGG CAACATCGTCACCTCCTTTGACACCCCCATTTCCCTCCTCCACTTTTGTTCCCCCCAAGGACCCTCCTAA TCCCACATCTCCACTTTTCCCTTTTTTTTTTTTTTTTAGCCAGGGTCTCGCTCTGTCGCCCAGGCTGGAG TGCAGTGGCTCAATCTCGGCTCACTGCAACCTCCGCCTCCCAGGTTCATGCAGTTCTCCTGCCTCAGCCT CCCGAGTACCTGGGATTACAGGCGTGCACCACTCCACCACACCAGGCTAATTTTTGTATTTTTAGTAGAG ACGGGGTTTCGCCATGTTGGCCAGGCTGGTCCTGAACTCCTGGCCTCAAGTGATCCTCCCGCCTCGGCCT CCCGAAGTGCTGGGATTACAGGCCTGAGCCACCACGCCGGGCCTCCACTTTTCCTAATCCGGCTTCTCCA CCAGGCTCTCGCAGGTGATCCCTCCTGAGCCCCAGTCCCCCCACCCCACTTGTCCTCTGTATGCTCACTC CTCTCCGTGGTCCCCGAGCCCCAGGACTGGTCCCCACTGCAGCACGCCCCCTCCTCAGCCTCCAGGCTGA CCCTCCCCTCCGCTTCCCTCCCCTGCAGACTCTGGGCTGGGAAGCCCTGTTGGCCCGGCGCCTGCCACCG CCCTTTGTGCCCACGCTGTCCGGCCGCACCGACGTCAGCAACTTCGACGAGGAGTTCACCGGGGAGGCCC CCACACTGAGCCCGCCCCGCGACGCGCGGCCCCTCACAGCCGCGGAGCAGGCAGCCTTCCTGGACTTCGA CTTCGTGGCCGGGGGCTGCTAGCCCCCTCCCCTGCCCCTGCCCCTGCCCCTGCCCGAGAGCTCTTAGTTT TTAAAAAGGCCTTTGGGATTTGCCGGATCCTTGCA Download Select all
Length	38815
OMIM ID	601032
HGNC ID	HGNC:9405
Unigene ID	Hs.466044
Ensembl ID	ENSG00000123143
PharmGKB ID	-

mRNA Information

mRNA ID	XM_011528129.1
Exon	join(1..118,8091..8391,10418..10569,13374..13509, 17266..17411,17844..18057,18777..18971,24979..25088, 25180..25323,30615..30690,30776..30917,31008..31101, 34513..34589,34666..34741,34824..34915,36289..36465, 36700..36762,36860..36936,37111..37253,37523..37630, 37719..37799,38529..38815)
mRNA Sequence	>5585 ACGCGGCGGCCTGGCCAGGCGAGGCGGGAGCCGAGCAGGCCGGAGCGGGCCGCGCGCCGGGGAG GGTCGCGCCGCGCCCGCCCCCTCCCCGCCACGCCCGGGGCGCACGCGCGCTCCTCTGGCCGCCC CTCCCTCCGCGCGGGGACCCCTGGCGGGCGGCAGGAGGACATGGCCAGCGACGCCGTGCAGAGT GAGCCTCGCAGCTGGTCCCTGCTAGAGCAGCTGGGCCTGGCCGGGGCAGACCTGGCGGCCCCCG GGGTACAGCAGCAGCTGGAGCTGGAGCGGGAGCGGCTGCGGCGGGAAATCCGCAAGGAGCTGAA GCTGAAGGAGGGTGCTGAGAACCTGCGGCGGGCCACCACTGACCTGGGCCGCAGCCTGGGCCCC GTAGAGCTGCTGCTGCGGGGCTCCTCGCGCCGCCTCGACCTGCTGCACCAGCAGCTGCAGGAGC TGCACGCCCACGTGGTGCTTCCCGACCCGGCGGCCACCCACGATGGCCCCCAGTCCCCTGGTGC GGGTGGCCCCACCTGCTCGGCCACCAACCTGAGCCGCGTGGCGGGCCTGGAGAAGCAGTTGGCC ATTGAGCTGAAGGTGAAGCAGGGGGCGGAGAACATGATCCAGACCTACAGCAATGGCAGCACCA AGGACCGGAAGCTGCTGCTGACAGCCCAGCAGATGTTGCAGGACAGTAAGACCAAGATTGACAT CATCCGCATGCAACTCCGCCGGGCGCTGCAGGCCGGCCAGCTGGAGAACCAGGCAGCCCCGGAT GACACCCAAGGGAGTCCTGACCTGGGGGCTGTGGAGCTGCGCATCGAAGAGCTGCGGCACCACT TCCGAGTGGAGCACGCGGTGGCCGAGGGTGCCAAGAACGTACTGCGCCTGCTCAGCGCTGCCAA GGCCCCGGACCGCAAGGCAGTCAGCGAGGCCCAGGAGAAATTGACAGAATCCAACCAGAAGCTG GGGCTGCTGCGGGAGGCTCTGGAGCGGAGACTTGGGGAGCTGCCCGCCGACCACCCCAAGGGGC GGCTGCTGCGAGAAGAGCTCGCTGCGGCCTCCTCCGCTGCCTTCAGCACCCGCCTGGCCGGGCC CTTTCCCGCCACGCACTACAGCACCCTGTGCAAGCCCGCGCCGCTCACAGGGACCCTGGAGGTA CGAGTGGTGGGCTGCAGAGACCTCCCAGAGACCATCCCGTGGAACCCTACCCCCTCAATGGGGG GACCTGGGACCCCAGACAGCCGCCCCCCCTTCCTGAGCCGCCCAGCCCGGGGCCTTTACAGCCG AAGCGGAAGCCTCAGTGGCCGGAGCAGCCTCAAAGCAGAAGCCGAGAACACCAGTGAAGTCAGC ACTGTGCTTAAGCTGGATAACACAGTGGTGGGGCAGACGTCTTGGAAGCCATGTGGCCCCAATG CCTGGGACCAGAGCTTCACTCTGGAGCTGGAAAGGGCACGGGAACTGGAGTTGGCTGTGTTCTG GCGGGACCAGCGGGGCCTGTGTGCCCTCAAATTCCTGAAGTTGGAGGATTTCTTGGACAATGAG AGGCATGAGGTGCAGCTGGACATGGAACCCCAGGGCTGCCTGGTGGCTGAGGTCACCTTCCGCA ACCCTGTCATTGAGAGGATTCCTCGGCTCCGACGGCAGAAGAAAATTTTCTCCAAGCAGCAAGG GAAGGCGTTCCAGCGTGCTAGGCAGATGAACATCGATGTCGCCACGTGGGTGCGGCTGCTCCGG AGGCTCATCCCCAATGCCACGGGCACAGGCACCTTTAGCCCTGGGGCTTCTCCAGGATCCGAGG CCCGGACCACGGGTGACATATCGGTGGAGAAGCTGAACCTCGGCACTGACTCGGACAGCTCACC TCAGAAGAGCTCGCGGGATCCTCCTTCCAGCCCATCGAGCCTGAGCTCCCCCATCCAGGAATCC ACTGCTCCCGAGCTGCCTTCGGAGACCCAGGAGACCCCAGGCCCCGCCCTGTGCAGCCCTCTGA GGAAGTCACCTCTGACCCTCGAAGATTTCAAGTTCCTGGCGGTGCTGGGCCGGGGTCATTTTGG GAAGGTGCTCCTCTCCGAATTCCGGCCCAGTGGGGAGCTGTTCGCCATCAAGGCTCTGAAGAAA GGGGACATTGTGGCCCGAGACGAGGTGGAGAGCCTGATGTGTGAGAAGCGGATATTGGCGGCAG TGACCAGTGCGGGACACCCCTTCCTGGTGAACCTCTTCGGCTGTTTCCAGACACCGGAGCACGT GTGCTTCGTGATGGAGTACTCGGCCGGTGGGGACCTGATGCTGCACATCCACAGCGACGTGTTC TCTGAGCCCCGTGCCATCTTTTATTCCGCCTGCGTGGTGCTGGGCCTACAGTTTCTTCACGAAC ACAAGATCGTCTACAGGGACCTGAAGTTGGACAATTTGCTCCTGGACACCGAGGGCTACGTCAA GATCGCAGACTTTGGCCTCTGCAAGGAGGGGATGGGCTATGGGGACCGGACCAGCACATTCTGT GGGACCCCGGAGTTCCTGGCCCCTGAGGTGCTGACGGACACGTCGTACACGCGAGCTGTGGACT GGTGGGGACTGGGTGTGCTGCTCTACGAGATGCTGGTTGGCGAGTCCCCATTCCCAGGGGATGA TGAGGAGGAGGTCTTCGACAGCATCGTCAACGACGAGGTTCGCTACCCCCGCTTCCTGTCGGCC GAAGCCATCGGCATCATGAGAAGGCTGCTTCGGAGGAACCCAGAGCGGAGGCTGGGATCTAGCG AGAGAGATGCAGAAGATGTGAAGAAACAGCCCTTCTTCAGGACTCTGGGCTGGGAAGCCCTGTT GGCCCGGCGCCTGCCACCGCCCTTTGTGCCCACGCTGTCCGGCCGCACCGACGTCAGCAACTTC GACGAGGAGTTCACCGGGGAGGCCCCCACACTGAGCCCGCCCCGCGACGCGCGGCCCCTCACAG CCGCGGAGCAGGCAGCCTTCCTGGACTTCGACTTCGTGGCCGGGGGCTGCTAGCCCCCTCCCCT GCCCCTGCCCCTGCCCCTGCCCGAGAGCTCTTAGTTTTTAAAAAGGCCTTTGGGATTTGCCGGA TCCTTGCAAAAAAAAAAAAAAAAAA Download Select all
Length	3097

CDS Information

Location	join(470..490,8091..8391,10418..10569,13374..13509, 17266..17411,17844..18057,18777..18971,24979..25088, 25180..25323,30615..30690,30776..30917,31008..31101, 34513..34589,34666..34741,34824..34915,36289..36465, 36700..36762,36860..36936,37111..37253,37523..37630, 37719..37799,38529..38732)
CDS Sequence	>gi\|47132588:169-2997 Homo sapiens protein kinase N1 (PKN1), transcript variant 2, mRNA ATGGCCAGCGACGCCGTGCAGAGTGAGCCTCGCAGCTGGTCCCTGCTAGAGCAGCTGGGCCTGGCCGGGG CAGACCTGGCGGCCCCCGGGGTACAGCAGCAGCTGGAGCTGGAGCGGGAGCGGCTGCGGCGGGAAATCCG CAAGGAGCTGAAGCTGAAGGAGGGTGCTGAGAACCTGCGGCGGGCCACCACTGACCTGGGCCGCAGCCTG GGCCCCGTAGAGCTGCTGCTGCGGGGCTCCTCGCGCCGCCTCGACCTGCTGCACCAGCAGCTGCAGGAGC TGCACGCCCACGTGGTGCTTCCCGACCCGGCGGCCACCCACGATGGCCCCCAGTCCCCTGGTGCGGGTGG CCCCACCTGCTCGGCCACCAACCTGAGCCGCGTGGCGGGCCTGGAGAAGCAGTTGGCCATTGAGCTGAAG GTGAAGCAGGGGGCGGAGAACATGATCCAGACCTACAGCAATGGCAGCACCAAGGACCGGAAGCTGCTGC TGACAGCCCAGCAGATGTTGCAGGACAGTAAGACCAAGATTGACATCATCCGCATGCAACTCCGCCGGGC GCTGCAGGCCGGCCAGCTGGAGAACCAGGCAGCCCCGGATGACACCCAAGGGAGTCCTGACCTGGGGGCT GTGGAGCTGCGCATCGAAGAGCTGCGGCACCACTTCCGAGTGGAGCACGCGGTGGCCGAGGGTGCCAAGA ACGTACTGCGCCTGCTCAGCGCTGCCAAGGCCCCGGACCGCAAGGCAGTCAGCGAGGCCCAGGAGAAATT GACAGAATCCAACCAGAAGCTGGGGCTGCTGCGGGAGGCTCTGGAGCGGAGACTTGGGGAGCTGCCCGCC GACCACCCCAAGGGGCGGCTGCTGCGAGAAGAGCTCGCTGCGGCCTCCTCCGCTGCCTTCAGCACCCGCC TGGCCGGGCCCTTTCCCGCCACGCACTACAGCACCCTGTGCAAGCCCGCGCCGCTCACAGGGACCCTGGA GGTACGAGTGGTGGGCTGCAGAGACCTCCCAGAGACCATCCCGTGGAACCCTACCCCCTCAATGGGGGGA CCTGGGACCCCAGACAGCCGCCCCCCCTTCCTGAGCCGCCCAGCCCGGGGCCTTTACAGCCGAAGCGGAA GCCTCAGTGGCCGGAGCAGCCTCAAAGCAGAAGCCGAGAACACCAGTGAAGTCAGCACTGTGCTTAAGCT GGATAACACAGTGGTGGGGCAGACGTCTTGGAAGCCATGTGGCCCCAATGCCTGGGACCAGAGCTTCACT CTGGAGCTGGAAAGGGCACGGGAACTGGAGTTGGCTGTGTTCTGGCGGGACCAGCGGGGCCTGTGTGCCC TCAAATTCCTGAAGTTGGAGGATTTCTTGGACAATGAGAGGCATGAGGTGCAGCTGGACATGGAACCCCA GGGCTGCCTGGTGGCTGAGGTCACCTTCCGCAACCCTGTCATTGAGAGGATTCCTCGGCTCCGACGGCAG AAGAAAATTTTCTCCAAGCAGCAAGGGAAGGCGTTCCAGCGTGCTAGGCAGATGAACATCGATGTCGCCA CGTGGGTGCGGCTGCTCCGGAGGCTCATCCCCAATGCCACGGGCACAGGCACCTTTAGCCCTGGGGCTTC TCCAGGATCCGAGGCCCGGACCACGGGTGACATATCGGTGGAGAAGCTGAACCTCGGCACTGACTCGGAC AGCTCACCTCAGAAGAGCTCGCGGGATCCTCCTTCCAGCCCATCGAGCCTGAGCTCCCCCATCCAGGAAT CCACTGCTCCCGAGCTGCCTTCGGAGACCCAGGAGACCCCAGGCCCCGCCCTGTGCAGCCCTCTGAGGAA GTCACCTCTGACCCTCGAAGATTTCAAGTTCCTGGCGGTGCTGGGCCGGGGTCATTTTGGGAAGGTGCTC CTCTCCGAATTCCGGCCCAGTGGGGAGCTGTTCGCCATCAAGGCTCTGAAGAAAGGGGACATTGTGGCCC GAGACGAGGTGGAGAGCCTGATGTGTGAGAAGCGGATATTGGCGGCAGTGACCAGTGCGGGACACCCCTT CCTGGTGAACCTCTTCGGCTGTTTCCAGACACCGGAGCACGTGTGCTTCGTGATGGAGTACTCGGCCGGT GGGGACCTGATGCTGCACATCCACAGCGACGTGTTCTCTGAGCCCCGTGCCATCTTTTATTCCGCCTGCG TGGTGCTGGGCCTACAGTTTCTTCACGAACACAAGATCGTCTACAGGGACCTGAAGTTGGACAATTTGCT CCTGGACACCGAGGGCTACGTCAAGATCGCAGACTTTGGCCTCTGCAAGGAGGGGATGGGCTATGGGGAC CGGACCAGCACATTCTGTGGGACCCCGGAGTTCCTGGCCCCTGAGGTGCTGACGGACACGTCGTACACGC GAGCTGTGGACTGGTGGGGACTGGGTGTGCTGCTCTACGAGATGCTGGTTGGCGAGTCCCCATTCCCAGG GGATGATGAGGAGGAGGTCTTCGACAGCATCGTCAACGACGAGGTTCGCTACCCCCGCTTCCTGTCGGCC GAAGCCATCGGCATCATGAGAAGGCTGCTTCGGAGGAACCCAGAGCGGAGGCTGGGATCTAGCGAGAGAG ATGCAGAAGATGTGAAGAAACAGCCCTTCTTCAGGACTCTGGGCTGGGAAGCCCTGTTGGCCCGGCGCCT GCCACCGCCCTTTGTGCCCACGCTGTCCGGCCGCACCGACGTCAGCAACTTCGACGAGGAGTTCACCGGG GAGGCCCCCACACTGAGCCCGCCCCGCGACGCGCGGCCCCTCACAGCCGCGGAGCAGGCAGCCTTCCTGG ACTTCGACTTCGTGGCCGGGGGCTGCTAG Download Select all
CCDS ID	CCDS42513.1

Protein Information

Protein ID	NP_002732.3
Protein Name	Protein kinase N1
Molecular Wt. (Da)	103801
Protein Sequence	>5585 MASDAVQSEPRSWSLLEQLGLAGADLAAPGVQQQLELERERLRREIRKELKLKEGAENLRRATT DLGRSLGPVELLLRGSSRRLDLLHQQLQELHAHVVLPDPAATHDGPQSPGAGGPTCSATNLSRV AGLEKQLAIELKVKQGAENMIQTYSNGSTKDRKLLLTAQQMLQDSKTKIDIIRMQLRRALQAGQ LENQAAPDDTQGSPDLGAVELRIEELRHHFRVEHAVAEGAKNVLRLLSAAKAPDRKAVSEAQEK LTESNQKLGLLREALERRLGELPADHPKGRLLREELAAASSAAFSTRLAGPFPATHYSTLCKPA PLTGTLEVRVVGCRDLPETIPWNPTPSMGGPGTPDSRPPFLSRPARGLYSRSGSLSGRSSLKAE AENTSEVSTVLKLDNTVVGQTSWKPCGPNAWDQSFTLELERARELELAVFWRDQRGLCALKFLK LEDFLDNERHEVQLDMEPQGCLVAEVTFRNPVIERIPRLRRQKKIFSKQQGKAFQRARQMNIDV ATWVRLLRRLIPNATGTGTFSPGASPGSEARTTGDISVEKLNLGTDSDSSPQKSSRDPPSSPSS LSSPIQESTAPELPSETQETPGPALCSPLRKSPLTLEDFKFLAVLGRGHFGKVLLSEFRPSGEL FAIKALKKGDIVARDEVESLMCEKRILAAVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLM LHIHSDVFSEPRAIFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGY GDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEV RYPRFLSAEAIGIMRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTLS GRTDVSNFDEEFTGEAPTLSPPRDARPLTAAEQAAFLDFDFVAGGC Download Select all
Length	942
Uniprot ID	Q49AN0
Ensembl Protein ID	ENSP00000397419

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
S	Phosphorylation	916
S	Phosphorylation	922
D	Proteolytic Cleavage	108
D	Proteolytic Cleavage	454
D	Proteolytic Cleavage	558
D	Proteolytic Cleavage	560
D	Proteolytic Cleavage	457
D	Proteolytic Cleavage	564
D	Proteolytic Cleavage	566
S	Phosphorylation	372
S	Phosphorylation	374
S	Phosphorylation	380
T	Phosphorylation	531
S	Phosphorylation	576
S	Phosphorylation	608
T	Phosphorylation	64
S	Phosphorylation	378
S	Phosphorylation	380
T	Phosphorylation	537
S	Phosphorylation	582
S	Phosphorylation	614
T	Phosphorylation	70
T	Phosphorylation	774
T	Phosphorylation	780
D	Proteolytic Cleavage	114
D	Proteolytic Cleavage	460
D	Proteolytic Cleavage	451
S	Phosphorylation	562;-
S	Phosphorylation	568;-
S	Phosphorylation	559;-
S	Phosphorylation	565;-
S	Phosphorylation	376;-
S	Phosphorylation	382;-
S	Phosphorylation	533
S	Phosphorylation	537
S	Phosphorylation	539
S	Phosphorylation	543
T	Phosphorylation	778
T	Phosphorylation	784
S	Phosphorylation	561
S	Phosphorylation	567
S	Phosphorylation	205
S	Phosphorylation	211
T	Phosphorylation	353
T	Phosphorylation	359
T	Phosphorylation	772
T	Phosphorylation	778
T	Phosphorylation	557
T	Phosphorylation	563
K	Acetylation	448
K	Acetylation	454
S	Phosphorylation	240
S	Phosphorylation	246
T	Phosphorylation	914
T	Phosphorylation	920
S	Phosphorylation	902
S	Phosphorylation	908

Enzyme Information

EC	2.7.11.1
Name	non-specific serine/threonine protein kinase A-kinase AP50 kinase ATP-protein transphosphorylase calcium-dependent protein kinase C calcium/phospholipid-dependent protein kinase cAMP-dependent protein kinase cAMP-dependent protein kinase A casein kinase casein kinase (phosphorylating) casein kinase 2 casein kinase I casein kinase II cGMP-dependent protein kinase CK-2 CKI CKII cyclic AMP-dependent protein kinase cyclic AMP-dependent protein kinase A cyclic monophosphate-dependent protein kinase cyclic nucleotide-dependent protein kinase cyclin-dependent kinase cytidine 3',5'-cyclic monophosphate-responsive protein kinase dsk1 glycogen synthase a kinase glycogen synthase kinase HIPK2 Hpr kinase hydroxyalkyl-protein kinase hydroxyalkyl-protein kinase M phase-specific cdc2 kinase mitogen-activated S6 kinase p82 kinase phosphorylase b kinase kinase PKA protein glutamyl kinase protein kinase (phosphorylating) protein kinase A protein kinase CK2 protein kinase p58 protein phosphokinase protein serine kinase protein serine-threonine kinase protein-aspartyl kinase protein-cysteine kinase protein-serine kinase Prp4 protein kinase Raf kinase Raf-1 ribosomal protein S6 kinase II ribosomal S6 protein kinase serine kinase serine protein kinase serine-specific protein kinase serine(threonine) protein kinase serine/threonine protein kinase STK32 T-antigen kinase threonine-specific protein kinase twitchin kinase type-2 casein kinase betaIIPKC epsilon PKC Wee 1-like kinase Wee-kinase WEE1Hu
Class	Transferases; Transferring phosphorus-containing groups; Protein-serine/threonine kinases
Sysname	ATP:protein phosphotransferase (non-specific)
Substrate	ATP [CPD:C00002]; protein
Product	ADP [CPD:C00008]; phosphoprotein
Reaction (IUBMB)

PPi Information

(Click to view network : Source STRING) View

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
87	ACTN1	20	NP_001123476.1	in vitro;in vivo;yeast 2-hybrid	118 027 089 030 526
387	RHOA	1323	NP_001655.1	in vitro;in vivo	9 446 575 857 112 710 000 000
995	CDC25C	1146	NP_001781.2	in vitro	15791647
4082	MARCKS	7519	NP_002347.5	in vitro	119 301 788 557 118
4137	MAPT	1142	NP_001116538.1	in vitro;in vivo	954 667 212 435 421 000 000 000 000 000 000 000 000 000 000
4744	NEFH	1204	NP_066554.2	in vitro;in vivo	8621664
4747	NEFL	1206	NP_006149.2	in vitro;yeast 2-hybrid	8621664
5608	MAP2K6	3155	NP_002749.2	in vitro;in vivo	12761180
6300	MAPK12	3868	NP_002960.2	in vitro;in vivo	12761180
7186	TRAF2	3538	NP_066961.2	in vitro;in vivo;yeast 2-hybrid	14741690
7431	VIM	1899	NP_003371.2	in vitro;yeast 2-hybrid	9175763
10142	AKAP9	4921	NP_671700.1	in vitro;in vivo	10358086
11007	CCDC85B	16101	NP_006839.2	yeast 2-hybrid	16189514

Pathway Information

Pathway Name	Pathway ID
PI3K-Akt signaling pathway	hsa04151
Salmonella infection	hsa05132

Structure Information

PDB ID	1CXZ
Resolution	2.1
Method	X-RAY DIFFRACTION
Chains	A
Molecule	PROTEIN (HIS-TAGGED TRANSFORMING PROTEIN RHOA(0-181))
Model	View

Domain Information

ID	Location	Description
cd05589	615-939	STKc_PKN
cl21453	615-939	PKc_like superfamily
cd11630	121-196	HR1_PKN1_2
cl00087	121-196	HR1 superfamily
cd11636	205-278	HR1_PKN1_3
cl00087	205-278	HR1 superfamily
cd08687	389-476	C2_PKN-like
cl14603	389-476	C2 superfamily
cd11622	46-98	HR1_PKN_1
cl00087	46-98	HR1 superfamily
cd05570	619-938	STKc_PKC
cd05571	620-939	STKc_PKB
cd05592	619-938	STKc_nPKC_theta_like
cd05587	618-938	STKc_cPKC
cd05591	620-938	STKc_nPKC_epsilon
cd05619	610-938	STKc_nPKC_theta
cd05590	620-939	STKc_nPKC_eta
cd05616	614-938	STKc_cPKC_beta
cd05620	620-938	STKc_nPKC_delta
cd05575	620-938	STKc_SGK
cd05595	620-939	STKc_PKB_beta
cd05615	612-938	STKc_cPKC_alpha
cd05123	621-874	STKc_AGC
cd05580	613-905	STKc_PKA_like
cd05594	590-918	STKc_PKB_alpha
cd05584	618-939	STKc_p70S6K
cd05593	611-918	STKc_PKB_gamma
cd05588	620-938	STKc_aPKC
cd05604	618-911	STKc_SGK3
cd05603	619-938	STKc_SGK2
cd05582	620-938	STKc_RSK_N
cd05585	620-937	STKc_YPK1_like
cd14209	613-906	STKc_PKA
cd05586	621-937	STKc_Sck1_like
cd05618	608-938	STKc_aPKC_iota
cd05617	610-938	STKc_aPKC_zeta
cd05572	621-881	STKc_cGK
cd05614	614-939	STKc_MSK2_N
cd05602	614-937	STKc_SGK1
cd05612	613-905	STKc_PRKX_like
cd05573	613-937	STKc_ROCK_NDR_like
cd05599	613-938	STKc_NDR_like
cd05574	614-900	STKc_phototropin_like
cd05579	623-879	STKc_MAST_like
cd05577	621-893	STKc_GRK
cd05583	620-877	STKc_MSK_N
cd05608	614-893	STKc_GRK1
cd05598	614-937	STKc_LATS
cd05613	614-893	STKc_MSK1_N
cd05605	615-893	STKc_GRK4_like
cd05609	614-879	STKc_MAST
cd05581	613-874	STKc_PDK1
cd05631	615-893	STKc_GRK4
cd05578	615-874	STKc_Yank1
cd05601	613-938	STKc_CRIK
cd05117	614-873	STKc_CAMK
cd14007	614-875	STKc_Aurora
cd05611	623-880	STKc_Rim15_like
cd05596	605-919	STKc_ROCK
cd05600	606-913	STKc_Sid2p_like
cd14003	614-858	STKc_AMPK-like
cd05632	615-893	STKc_GRK5
cd05597	613-937	STKc_DMPK_like
cd05610	611-905	STKc_MASTL
cd05607	620-893	STKc_GRK7
cd05630	615-893	STKc_GRK6
cd05621	605-937	STKc_ROCK2
cd05606	620-893	STKc_beta_ARK
cd05622	603-919	STKc_ROCK1
cd05624	605-942	STKc_MRCK_beta
cd05629	613-937	STKc_NDR_like_fungal
cd06606	620-874	STKc_MAPKKK
cd14223	614-909	STKc_GRK2
cd05623	603-918	STKc_MRCK_alpha
cd05633	610-909	STKc_GRK3
cd05626	615-937	STKc_LATS2
cd05627	612-937	STKc_NDR2
cd08215	614-874	STKc_Nek
cd05625	615-905	STKc_LATS1
cd00180	621-872	PKc
cd14008	621-874	STKc_LKB1_CaMKK
cd05628	613-906	STKc_NDR1
cd05122	614-874	PKc_STE
cd14099	621-874	STKc_PLK
cd14073	615-857	STKc_NUAK
cd14009	621-859	STKc_ATG1_ULK_like
cd14663	614-862	STKc_SnRK3
cd14161	615-857	STKc_NUAK2
cd14006	621-862	STKc_MLCK-like
cd13999	621-857	STKc_MAP3K-like
cd14075	615-862	STKc_NIM1
cd11623	121-190	HR1_PKN_2
cd14095	615-862	STKc_DCKL
cd14116	611-858	STKc_Aurora-A
cd14186	613-861	STKc_PLK4
cd06623	613-857	PKc_MAPKK_plant_like
cd14014	615-862	STKc_PknB_like
cd08530	614-862	STKc_CNK2-like
cd14084	620-858	STKc_Chk2
cd14072	615-857	STKc_MARK
cd14098	614-862	STKc_Rad53_Cds1
cd14106	621-858	STKc_DRAK
cd14083	615-857	STKc_CaMKI
cd14081	621-874	STKc_BRSK1_2
cd14166	613-857	STKc_CaMKI_gamma
cd14080	615-874	STKc_TSSK-like
cd14002	613-859	STKc_STK36
cd14117	610-890	STKc_Aurora-B_like
cd14103	621-862	STKc_MLCK
cd14076	621-858	STKc_Kin4
cd11625	206-278	HR1_PKN_3
cd11631	119-189	HR1_PKN2_2
cd14187	621-857	STKc_PLK1
cd14079	621-874	STKc_AMPK_alpha
cd14167	613-857	STKc_CaMKI_alpha
cd14198	621-857	STKc_DRAK2
cd06614	615-874	STKc_PAK
cd14077	614-862	STKc_Kin1_2
cd06627	621-857	STKc_Cdc7_like
cd00192	620-857	PTKc
cd14078	621-858	STKc_MELK
cd14091	614-895	STKc_RSK_C
cd14074	621-857	STKc_SNRK
cd14197	621-874	STKc_DRAK1
cd14004	614-857	STKc_PASK
cd14069	613-874	STKc_Chk1
cd14168	613-857	STKc_CaMKI_delta
cd14118	621-862	STKc_CAMKK
cd14169	621-858	STKc_CaMKI_beta
cd14087	615-862	STKc_PSKH1
cd14185	620-857	STKc_DCKL3
cd06612	613-815	STKc_MST1_2
cd06632	621-857	STKc_MEKK1_plant
cd14097	615-862	STKc_STK33
cd06611	621-874	STKc_SLK_like
cd08222	621-862	STKc_Nek11
cd14093	620-874	STKc_PhKG
cd11632	127-191	HR1_PKN3_2
cd14121	621-858	STKc_ULK3
cd08529	614-857	STKc_FA2-like
cd14188	620-857	STKc_PLK2
cd14665	615-862	STKc_SnRK2-3
cd06917	615-876	STKc_NAK1_like
cd14010	621-873	STKc_ULK4
cd14086	621-862	STKc_CaMKII
cd06643	613-862	STKc_SLK
cd11635	206-278	HR1_PKN2_3
cd14096	613-857	STKc_RCK1-like
cd06644	621-857	STKc_STK10
cd08219	614-857	STKc_Nek3
cd14070	621-862	STKc_HUNK
cd14662	621-873	STKc_SnRK2
cd08218	621-857	STKc_Nek1
cd08225	615-857	STKc_Nek5
cd14061	620-819	STKc_MLK
cd14192	620-862	STKc_MLCK3
cd06609	613-814	STKc_MST3_like
cd06628	619-873	STKc_Byr2_like
cd05118	615-874	STKc_CMGC
cd14071	620-859	STKc_SIK
cd14082	620-857	STKc_PKD
cd14059	621-835	STKc_MAP3K12_13
cd14164	615-857	STKc_TSSK6-like
cd14105	612-858	STKc_DAPK
cd14200	615-862	STKc_CaMKK1
cd06625	619-857	STKc_MEKK3_like
cd06648	621-875	STKc_PAK_II
cd06605	613-874	PKc_MAPKK
cd14193	620-862	STKc_MLCK4
cd06610	613-815	STKc_OSR1_SPAK
cd14199	612-862	STKc_CaMKK2
cd07830	615-874	STKc_MAK_like
cd14114	612-858	STKc_Twitchin_like
cd14194	621-858	STKc_DAPK1
cd14090	620-873	STKc_Mnk
cd14094	613-862	STKc_CASK
cd07832	614-874	STKc_CCRK
cd06608	613-815	STKc_myosinIII_N_like
cd14184	613-873	STKc_DCKL2
cd14104	615-862	STKc_Titin
cd14190	620-862	STKc_MLCK2
cd06647	675-875	STKc_PAK_I
cd13993	615-867	STKc_Pat1_like
cd06613	614-814	STKc_MAP4K3_like
cd11637	208-278	HR1_PKN3_3
cd08217	614-857	STKc_Nek2
cd14107	621-862	STKc_obscurin_rpt1
cd14085	621-858	STKc_CaMKIV
cd07846	613-862	STKc_CDKL2_3
cd06655	621-875	STKc_PAK2
cd14120	675-873	STKc_ULK1_2-like
cd06615	613-875	PKc_MEK
cd13994	621-874	STKc_HAL4_like
cd06656	621-875	STKc_PAK3
cd14181	620-874	STKc_PhKG2
cd13978	621-857	STKc_RIP
cd07829	615-874	STKc_CDK_like
cd14162	620-874	STKc_TSSK4-like
cd14147	611-819	STKc_MLK3
cd14119	621-874	STKc_LKB1
cd14189	620-858	STKc_PLK3
cd05072	613-857	PTKc_Lyn
cd06654	621-862	STKc_PAK1
cd14092	621-862	STKc_MSK_C
cd06629	621-873	STKc_Bck1_like
cd05038	616-809	PTKc_Jak_rpt2
cd14195	621-858	STKc_DAPK3
cd06630	619-875	STKc_MEKK1
cd14183	609-835	STKc_DCKL1
cd14191	621-862	STKc_MLCK1
cd13997	614-857	PKc_Wee1_like
cd14113	618-857	STKc_Trio_C
cd14182	620-875	STKc_PhKG1
cd14089	620-858	STKc_MAPKAPK
cd05055	613-857	PTKc_PDGFR
cd06621	613-862	PKc_Pek1_like
cd06638	613-862	STKc_myosinIIIA_N
cd14175	641-873	STKc_RSK1_C
cd06640	613-814	STKc_MST4
cd14179	620-861	STKc_MSK1_C
cd06624	620-862	STKc_ASK
cd14019	613-874	STKc_Cdc7
cd13987	621-857	STKc_SBK1
cd14180	621-862	STKc_MSK2_C
cd08223	614-857	STKc_Nek4
cd06653	613-873	STKc_MEKK3_like_u1
cd13979	616-863	STKc_Mos
cd06659	612-893	STKc_PAK6
cd14176	641-862	STKc_RSK2_C
cd14196	612-862	STKc_DAPK2
cd14172	613-858	STKc_MAPKAPK3
cd06641	613-814	STKc_MST3
cd14178	641-858	STKc_RSK3_C
cd14145	608-819	STKc_MLK1
cd14165	621-862	STKc_TSSK1_2-like
cd13996	612-862	STKc_EIF2AK
cd05054	613-857	PTKc_VEGFR
cd14146	620-819	STKc_MLK4
cd06642	615-815	STKc_STK25
cd06652	620-815	STKc_MEKK2
cd05081	615-809	PTKc_Jak3_rpt2
cd06639	613-815	STKc_myosinIIIB_N
cd14201	611-874	STKc_ULK2
cd13990	675-857	STKc_TLK
cd06657	621-878	STKc_PAK4
cd06650	613-823	PKc_MEK1
cd06636	615-815	STKc_MAP4K4_6_N
cd05032	613-858	PTKc_InsR_like
cd14148	620-815	STKc_MLK2
cd14177	641-829	STKc_RSK4_C
cd07841	615-877	STKc_CDK7
cd14202	620-874	STKc_ULK1
cd07838	615-862	STKc_CDK4_6_like
cd06622	613-857	PKc_PBS2_like
cd05059	614-877	PTKc_Tec_like
cd06626	622-862	STKc_MEKK4
cd07833	613-874	STKc_CDKL
smart00133	879-939	S_TK_X
cl11395	879-939	Pkinase_C superfamily
cd05576	613-874	STKc_RPK118_like
cd05053	610-857	PTKc_FGFR
cd14207	613-870	PTKc_VEGFR1
cd07845	611-894	STKc_CDK10
cd05080	615-809	PTKc_Tyk2_rpt2
cd08220	614-808	STKc_Nek8
cd14005	615-858	STKc_PIM
cd06658	621-878	STKc_PAK5
cd07840	615-874	STKc_CDK9_like
cd06633	613-862	STKc_TAO3
cd14171	621-858	STKc_MAPKAPK5
cd06637	615-815	STKc_TNIK
cd00089	122-190	HR1
pfam02185	127-189	HR1
cd14039	621-815	STKc_IKK_alpha
cd14109	621-858	PK_Unc-89_rpt1
cd14052	614-807	PTKc_Wee1_fungi
cd14170	613-862	STKc_MAPKAPK2
cd06620	610-857	PKc_Byr1_like
cd14111	613-857	STKc_SPEG_rpt2
cd14174	620-862	STKc_Mnk1
cd14131	618-858	PKc_Mps1
cd06649	613-823	PKc_MEK2
cd08528	614-857	STKc_Nek10
cd05039	610-829	PTKc_Csk_like
cd06645	606-814	STKc_MAP4K3
cd05045	620-857	PTKc_RET
cd06631	620-873	STKc_YSK4
smart00742	213-273	Hr1
cd14205	615-809	PTKc_Jak2_rpt2
cd14047	613-862	STKc_EIF2AK2_PKR
smart00742	126-186	Hr1
cd05101	621-824	PTKc_FGFR2
cd07836	615-874	STKc_Pho85
cd05082	610-816	PTKc_Csk
cd05099	621-857	PTKc_FGFR4
cd14088	626-862	STKc_CaMK_like
cd08221	617-874	STKc_Nek9
cd14038	621-815	STKc_IKK_beta
cd14133	615-862	PKc_DYRK_like
cd06651	607-815	STKc_MEKK3
cd14173	620-862	STKc_Mnk2
cd05100	621-857	PTKc_FGFR3
cd06619	613-816	PKc_MKK5
cd05112	613-857	PTKc_Itk
cd06646	605-808	STKc_MAP4K5
cd05057	615-836	PTKc_EGFR_like
cd05098	621-824	PTKc_FGFR1
cd08224	614-818	STKc_Nek6_7
cd05148	613-857	PTKc_Srm_Brk
cd05085	620-866	PTKc_Fer
cd14022	767-862	PK_TRB2
cd14064	621-815	PKc_TNNI3K
cd06635	615-862	STKc_TAO1
cd05089	613-857	PTKc_Tie1
cd06618	606-857	PKc_MKK7
cd05114	614-857	PTKc_Tec_Rlk
cd08229	611-818	STKc_Nek7
cd05113	613-857	PTKc_Btk_Bmx
cd05102	620-857	PTKc_VEGFR3
cd08228	612-818	STKc_Nek6
cd13985	620-857	STKc_GAK_like
cd14110	611-862	STKc_obscurin_rpt2
cd05067	613-857	PTKc_Lck_Blk
cd14066	621-867	STKc_IRAK
cd14060	622-857	STKc_MLTK
cd05084	621-857	PTKc_Fes
cd13983	615-815	STKc_WNK
cd05073	613-857	PTKc_Hck
cd13989	621-815	STKc_IKK
cd06634	615-815	STKc_TAO2
cd05041	621-857	PTKc_Fes_like
cd05046	618-835	PTK_CCK4
cd14023	767-862	PK_TRB1
cd06607	615-808	STKc_TAO
cd07866	611-874	STKc_BUR1
cd14154	621-809	STKc_LIMK
pfam02185	213-278	HR1
cd07873	612-878	STKc_PCTAIRE1
cd07847	613-874	STKc_CDKL1_4
cd05060	621-817	PTKc_Syk_like
cd05047	620-857	PTKc_Tie
cd14068	620-862	STKc_LRRK2
cd14046	612-862	STKc_EIF2AK4_GCN2_rpt2
cd13976	636-862	PK_TRB
cd07831	615-874	STKc_MOK
cd14210	615-828	PKc_DYRK
cd05034	621-857	PTKc_Src_like
smart00742	46-93	Hr1
cd05083	610-827	PTKc_Chk
cd14058	621-856	STKc_TAK1
cd05075	621-825	PTKc_Axl
cd07860	615-820	STKc_CDK2_3
cd05079	621-809	PTKc_Jak1_rpt2
cd14115	621-857	STKc_Kalirin_C
cd07843	613-874	STKc_CDC2L1
cd05092	621-858	PTKc_TrkA
cd07834	615-877	STKc_MAPK
cd05088	610-857	PTKc_Tie2
cd14108	621-874	STKc_SPEG_rpt1
cd05090	610-857	PTKc_Ror1
cd07872	612-878	STKc_PCTAIRE2
cd14000	620-857	STKc_LRRK
cd05040	621-857	PTKc_Ack_like
cd14024	689-862	PK_TRB3
cd14101	620-857	STKc_PIM2
cd07855	613-891	STKc_ERK5
cd05074	620-857	PTKc_Tyro3
cd14664	621-843	STK_BAK1_like
cd07851	615-862	STKc_p38
cd05091	610-832	PTKc_Ror2
cd00089	46-98	HR1
cd05048	610-827	PTKc_Ror
cd07871	612-822	STKc_PCTAIRE3
cd14222	621-809	STKc_LIMK2
cd05116	621-859	PTKc_Syk
cd07848	615-857	STKc_CDKL5
cd07862	613-827	STKc_CDK6
cd14012	632-862	PK_eIF2AK_GCN2_rpt1
cd05111	614-825	PTK_HER3
cd05063	620-835	PTKc_EphR_A2
cd07849	613-873	STKc_ERK1_2_like
cd14065	621-809	PKc_LIMK_like
cd05036	613-857	PTKc_ALK_LTK
cd05044	621-858	PTKc_c-ros
cd14163	665-874	STKc_TSSK3-like
cd07854	691-874	STKc_MAPK4_6
pfam00433	894-939	Pkinase_C
cd05103	621-862	PTKc_VEGFR2
cd13986	615-857	STKc_16
cd14204	620-857	PTKc_Mer
cd05035	615-857	PTKc_TAM
cd00089	212-278	HR1
cd13982	724-874	STKc_IRE1
cd05108	614-857	PTKc_EGFR
cd14221	621-809	STKc_LIMK1
cd05068	616-879	PTKc_Frk_like
cd14229	615-834	STKc_HIPK3
cd14063	614-821	PK_KSR
cd14040	609-874	STKc_TLK1
pfam02185	46-98	HR1
cd13988	621-815	STKc_TBK1
cd05115	621-815	PTKc_Zap-70
cd14112	613-862	STKc_Unc-89_rpt2
cd13974	707-862	STKc_SHIK
cd05105	724-857	PTKc_PDGFR_alpha
cd14048	612-809	STKc_EIF2AK3_PERK
cd07880	613-877	STKc_p38gamma
cd05110	614-836	PTKc_HER4
cd07835	615-874	STKc_CDK1_CdkB_like
cd05094	621-862	PTKc_TrkC
cd07877	613-819	STKc_p38alpha
cd07852	728-874	STKc_MAPK15-like
cd14050	615-857	PKc_Myt1
cd07869	613-824	STKc_PFTAIRE1
cd07839	621-874	STKc_CDK5
cd14102	619-857	STKc_PIM3
cd14011	724-875	PK_SCY1_like
cd05093	621-862	PTKc_TrkB
cd05033	616-835	PTKc_EphR
cd14026	618-815	STKc_RIP2
cd05050	621-857	PTKc_Musk
cd05058	620-816	PTKc_Met_Ron
cd05106	616-857	PTKc_CSF-1R
cd07870	618-817	STKc_PFTAIRE2
cd14227	615-834	STKc_HIPK2
cd05107	720-857	PTKc_PDGFR_beta
cd14041	611-874	STKc_TLK2
cd14203	621-857	PTKc_Src_Fyn_like
cd14137	620-877	STKc_GSK3
cd13995	623-862	STKc_MAP3K8
cd07863	727-836	STKc_CDK4
cd14224	615-820	PKc_DYRK2_3
cd11625	127-189	HR1_PKN_3
cd05049	612-858	PTKc_Trk
cd05052	621-825	PTKc_Abl
cd14138	614-862	PTKc_Wee1a
cd05070	613-827	PTKc_Fyn
cd05065	616-830	PTKc_EphR_B
cd05087	617-836	PTKc_Aatyk1
cd05056	613-835	PTKc_FAK
cd05109	614-892	PTKc_HER2
cd07878	700-819	STKc_p38beta
cd07856	621-867	STKc_Sty1_Hog1
cd14158	621-815	STKc_IRAK4
cd14150	618-815	STKc_A-Raf
cd14228	615-834	STKc_HIPK1
cd07879	618-874	STKc_p38delta
cd11627	122-189	HR1_Ste20-like
cd13975	675-816	PKc_Dusty
cd06616	611-827	PKc_MKK4
cd05066	620-827	PTKc_EphR_A
cd13977	688-809	STKc_PDIK1L
cd14062	621-817	STKc_Raf
cd05071	613-857	PTKc_Src
cd05061	613-857	PTKc_InsR
cd13992	633-857	PK_GC
cd07857	615-819	STKc_MPK1
cd11637	117-190	HR1_PKN3_3
cd05042	621-836	PTKc_Aatyk
cd07859	615-877	STKc_TDY_MAPK
cd07858	727-877	STKc_TEY_MAPK
cd14033	655-815	STKc_WNK4
cd13991	621-862	STKc_NIK
cd05069	613-857	PTKc_Yes
cd07837	613-874	STKc_CdkB_plant
cd14134	615-816	PKc_CLK
cd14100	620-857	STKc_PIM1
cd05051	613-857	PTKc_DDR
cd05097	621-826	PTKc_DDR_like
cd07875	724-828	STKc_JNK1
cd14149	621-824	STKc_C-Raf
cd07850	675-819	STKc_JNK
cd14215	613-822	PKc_CLK2
cd14159	621-818	STKc_IRAK1
cd07842	615-821	STKc_CDK8_like
cd14031	675-858	STKc_WNK3
cd14151	681-815	STKc_B-Raf
cd06617	613-815	PKc_MKK3_6
cd05096	617-826	PTKc_DDR1
cd07876	665-828	STKc_JNK2
cd07844	727-822	STKc_PCTAIRE_like
cd14211	615-834	STKc_HIPK
cd14136	621-819	STKc_SRPK
cd07874	724-828	STKc_JNK3
cd07864	612-873	STKc_CDK12
cd05104	720-857	PTKc_Kit
cd04014	395-468	C2_PKC_epsilon
cd14037	620-857	STKc_NAK_like
cd11632	214-268	HR1_PKN3_2
cd14027	621-874	STKc_RIP1
cd14057	636-857	PK_ILK
cd14225	615-822	PKc_DYRK4
cd14056	620-858	STKc_TGFbR_I
cd14032	675-815	STKc_WNK2_like
cd05062	678-857	PTKc_IGF-1R
cd11630	214-275	HR1_PKN1_2
cd11635	118-188	HR1_PKN2_3
cd11631	214-268	HR1_PKN2_2
cd11627	212-273	HR1_Ste20-like
cd11622	131-190	HR1_PKN_1
smart00220	615-874	S_TKc
PTZ00263	612-935	PTZ00263
pfam00069	615-874	Pkinase
PTZ00426	604-905	PTZ00426
COG0515	614-883	SPS1
pfam07714	615-877	Pkinase_Tyr
smart00219	616-857	TyrKc
smart00221	616-857	STYKc
PHA03390	624-874	pk1
PTZ00267	663-857	PTZ00267
PTZ00283	620-861	PTZ00283
PTZ00024	613-862	PTZ00024
PLN00034	587-858	PLN00034
PHA03212	627-856	PHA03212
PHA03209	724-875	PHA03209
PTZ00036	615-877	PTZ00036
PTZ00266	612-815	PTZ00266
TIGR03903	664-866	TOMM_kin_cyc
PRK13184	612-860	pknD
PLN00009	612-824	PLN00009

Ontology Information

HPRD ID	3217
Molecular Class	Serine/threonine kinase
Molecular Function	Transporter activity (GO:0005215)
Biological Process	Transport (GO:0006810)

SNP Information

View SNP Geneview Report

Drug Information

No matching records could be found.

External Links

ArrayExpress GO
ICGC GO
Cancer3D GO
COSMIC GO
NCG GO
TSGene GO
Tumor Gene Family of Databases GO
CCDB GO
G2SBC GO
Osteosarcoma Database GO
RCDB GO

ArrayExpress	GO
ICGC	GO
Cancer3D	GO
COSMIC	GO
NCG	GO
TSGene	GO
Tumor Gene Family of Databases	GO
CCDB	GO
G2SBC	GO
Osteosarcoma Database	GO
RCDB	GO