Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| PRDM1 | 639 | PR domain containing 1, with ZNF domain | 6 | BLIMP1; PRDI-BF1 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 22930170 | 2012 | Cell line : KM12C, KM12SM, HT 29 Source : ATCC Sample Type : - No. of Sample : - Stage : - | Microarray analysis,Real time RT-PCR and Flow cytometry | Up-regulation | - | Gene differentially expressed and analysed bye by Microarray. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Zinc fingers, C2H2-type |
| Description | This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported. [provided by RefSeq, Jul 2008] | Chromosome | 6 |
| Location | 6q21 |
| Start | 106086320 |
| End | 106109939 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 23620 |
| OMIM ID | 603423 |
| HGNC ID | HGNC:9346 |
| Unigene ID | Hs.436023 |
| Ensembl ID | ENSG00000057657 |
| PharmGKB ID | - |
mRNA Information
| mRNA ID | CCDS5054.2 |
|---|---|
| Exon | join(1..276,1882..2130,9296..9415,12981..13233, 18506..19614,20052..20180,20592..23620) | mRNA Sequence | Download Select all |
| Length | 5165 |
CDS Information
| Location | join(235..276,1882..2130,9296..9415,12981..13233, 18506..19614,20052..20180,20592..21167) |
|---|---|
| CDS Sequence | Download Select all |
| CCDS ID | CCDS5054.2 |
Protein Information
| Protein ID | NP_001189.2 |
|---|---|
| Protein Name | PR domain containing 1, with ZNF domain |
| Molecular Wt. (Da) | 91640 |
| Protein Sequence | Download Select all |
| Length | 825 |
| Uniprot ID | Q9UM73 |
| Ensembl Protein ID | ENSP00000373700 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 166 | AES | 2556 | NP_945320.1 | in vitro | 9887105 |
| 3662 | IRF4 | 3543 | NP_002451.2 | in vitro;in vivo | 11342629 |
| 6310 | ATXN1 | 3333 | NP_000323.2 | yeast 2-hybrid | 16713569 |
| 7088 | TLE1 | 2557 | NP_005068.2 | in vitro | 9887105 |
| 7089 | TLE2 | 3025 | NP_003251.2 | in vitro | 9887105 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| smart00317 | 100-206 | SET |
| cl02566 | 100-206 | SET superfamily |
| pfam00856 | 100-200 | SET |
| pfam13465 | 617-642 | zf-H2C2_2 |
| cl22375 | 617-642 | zf-H2C2_2 superfamily |
| pfam13465 | 589-614 | zf-H2C2_2 |
| cl22375 | 589-614 | zf-H2C2_2 superfamily |
| pfam13465 | 645-670 | zf-H2C2_2 |
| cl22375 | 645-670 | zf-H2C2_2 superfamily |
| pfam13465 | 673-694 | zf-H2C2_2 |
| cl22375 | 673-694 | zf-H2C2_2 superfamily |
| pfam00096 | 631-653 | zf-C2H2 |
| cl23491 | 631-653 | zf-C2H2 superfamily |
| pfam13912 | 631-653 | zf-C2H2_6 |
| cl16471 | 631-653 | zf-C2H2_6 superfamily |
| pfam12756 | 576-651 | zf-C2H2_2 |
| cl20464 | 576-651 | zf-C2H2_2 superfamily |
| pfam00096 | 575-597 | zf-C2H2 |
| cl23491 | 575-597 | zf-C2H2 superfamily |
| COG5048 | 570-688 | COG5048 |
| COG5048 | 601-658 | COG5048 |
| COG5189 | 516-678 | SFP1 |
| COG5189 | 623-707 | SFP1 |
Ontology Information
| HPRD ID | 104 |
|---|---|
| Molecular Class | Transcription factor |
| Molecular Function | Transmembrane receptor protein tyrosine kinase activity (GO:0004714) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.