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General Information
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
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Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 21765952 | 2011 | Cell line : 7 CRC cell lines Source : - Sample Type : CRC tumor and normal tissues No. of Sample : 8 CRC and Tissue microarray compose of 95 CRCs, 20 colorectal adenomas and 20 normal colorectal tissues Stage : - | RT-PCR and Western blotting, Immunohistochemistry, tissue microarrays | Unknown | - | TSP50 is a potential effective indicator of poor survival for CRC patients, especially for those with early-stage tumors. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Serine peptidases / Serine peptidases |
| Description | - | Chromosome | 3 |
| Location | 3p21.31 |
| Start | 46753606 |
| End | 46759373 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 5768 |
| OMIM ID | 607950 |
| HGNC ID | HGNC:17910 |
| Unigene ID | Hs.120365 |
| Ensembl ID | ENSG00000206549 |
| PharmGKB ID | PA165698443 |
Protein Information
| Protein ID | NP_037402.1 |
|---|---|
| Protein Name | protease, serine, 50 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 385 |
| Uniprot ID | Q9BXU1 |
| Ensembl Protein ID | ENSP00000346660 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00190 | 118-353 | Tryp_SPc |
| cl21584 | 118-353 | Tryp_SPc superfamily |
| smart00020 | 118-353 | Tryp_SPc |
| pfam00089 | 118-353 | Trypsin |
| COG5640 | 119-359 | COG5640 |
| pfam09342 | 124-284 | DUF1986 |
Ontology Information
| HPRD ID | 5683 |
|---|---|
| Molecular Class | Protease |
| Molecular Function | Metallopeptidase activity (GO:0008237) |
| Biological Process | Protein metabolism (GO:0019538) |
Drug Information
No matching records could be found.