CoReCG

Search results:

General Information

Gene_Symbol	Gene_ID	Gene_Name	Chromosome	Alias
PTCH1	5727	patched 1	9	BCNS

Evidence
Gene
mRNA
CDS
Protein
PTM
Enzyme
PPi
Pathway
Structural
Domain
Ontology
SNP
Drug
External Links

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
20230186	2010	Cell line : - Source : Jiangsu Institute of Cancer Research Sample Type : - No. of Sample : 19 primary tumors of CRC. Stage : TNM Stage I-III	real time RT-PCR, Flow cytometry	Down-regulation	-	PTCH1 might be a potential biomarker that could discriminate CRC with high from that with low metastatic risk. tumor tissues in the high-risk group for metastasis expressed lower levels of PTCH1 mRNA than did those in the low-risk group.

Gene Details

Chromosome 9 - NC_000009.12 (95442982..95516965, complement)
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Gene Type	protein coding
Gene Family
Description	This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently.
Chromosome	9
Location	9q22.1-q31
Start	95442982
End	95516965
Strand	-
Gene Sequence	>gi\|568815589:c95516965-95442982 Homo sapiens chromosome 9, GRCh38.p2 Primary Assembly ACCCAGGAGGGCTGTGCTGATAGCACGTTCCTCGAGTTTACTTTGCTTTCCTTGAGTTTATTGTAAAGGG GTAAAGTTTTCGGATCCGTCACGTGACCCTGACAGGTCCTGCCTATGGCGCGGCAGACCACCCACGCCGA GGGCCATGGAACTGCTTAATAGAAACAGGCTTGTAATTGTGAGTCCGCGCTGCACTCCGCCGAAAGCCTC CGGCGGCCCAGCGCGCCGGGGTTTTTACACTTTCCGTTCCTTTTGTAAAGACGGAGGAGGAGGAGAAGAA GAAGAAGAAAACGGAGGAGAAGAAAAAGACGACAGGGGAGACAAAGAGACCCGCAGCGACAAGGCAAGGG GGAGACGAGGGAAGACTGGGAGAAGACGGAGGAGCGGAGGACGAGGAAAGGGGGGCCAGGGAAAAAAAAG GAATTGATGTGAAATCCAAGCCCAGCGTCCGCGCCATCGGCACCCGCGCTCCGAGCAGGGGTTGACGGCC GGCTATGGTGAGTGCAGCCAGCGCGGCGGCCGCCGACGCCACCTCGCCTCGCGCGCCGTGCTCCTCGGGC GGCGCGGGGACACGGGGACGCGGGACGCCCCGCGCGGCGGACGGAGGAGCGAGCCCCGAGCGCCGGGCAG GAGGGGCGGGCCGCGCGCCGGGGCCGTGGAGCCGGGTGGGCTGCGCCGCCTGGGCGCGGGAGCGCGGGTC CCGCGCCTCCACGCTCGCTCGCACGCCCGGGCCCCCGCCCCCGAGGCCAGCCCCGCGTGGCGGGGAGGGG GCTGGCCGCGGCGGGCCCCGGCTGAGGAACGGCTCCGGGGGGAATTCTCACGGAGGGGGTCGCCGGAGCT CCCATTTTCACGCCTGAAAGGGTCGCCACCTTGGCTTCCGCTCATCAGCCTGGTGGTGGCTACTGACTCG CCAGCGGAGGCAGAGCTGGTGATGGAAGGGCTGGTGCGGAGAGTGACAGCGCCGAGGGGAGGGGGCTCAG AGCGCGCGCGCGGAAGCCGCTGCCGCCAGCTCGCGGGAGCAGCCGCAGCCGCAGGGAAGGGCACGCTCGC GCCCCGCAGACCCGCTCTCGAGCCCGCACGCACGCCTAGGGGTGCGGGACACCCGGGCTAGAAGAGACGC ACCTTACCCACCTCCCCTCCCATGCTGCGGGAAAAGGGCCAGAGAGGCTTTTGGAGTTCTGGAAGGGGCG GTGGGTAAGAGAGGTGGTGTGTGTGACTCTTATGCCCACCGATTCAGGCGCTTGGGTGGCTGCCACCCTT ACAGAGATGGGCGACCAGCCCAGTGCTTAGAGTGCAGAGTGCGGCCTCAGGGGAGCCCGGGGGCGGGCCG GACCGATTCTCACTTTACAGGCCCGGGCCCAGCGCTGAACCCCAAGACCCCCAGAAACTGTGCCTCTGGG TGACATGCGCTGTGTCTCCACGTATTTAGTACGTTCATGTTTAAAATGATGCTAGCGTGTGGATGAGCAC ACTCTCAGGGAAACTGATCTGTTTCCATCACCTAAGAAGAACCATATGGGTGGGCGGCTGTGGAAGACAC CCACAGACCTGTTTTCCTGCACCTGGGAGAGAAGACCGTCTTCCTCCCTTTTTATCCTTTCTTCCTCCCT GGGGAGGAGAAATACAAAAGAACTAGACATAAATAATAAAGAGCCACAATGGGTGGCTCTAAATATTTGA TAATTGGATCACTGAGGTCTTGAACTACCACAATAGTCCTTTTTCAGCATTCTGTGTGTGTGCATTTCTT TTAGGTTTTTATTTATTTCTGTGTTTATTGGCGACAGTAGTTCAGCATGCAATTAATCGCCTCCACAAAG AAAGACAATGCTTTATGGTGTCATCCTTTGTTATTGCAACTTAAAATTTCTGGGTGGTACTCCGGATAAA TTGTTGCCTCAGGTGCATGGAGTGCCCAAGTTGTAAAACAAGGGGCTTTCGATTGTGAGTTTATGTGTGT TCCAGTTGTCACCCAGCTTCCTTCCACAAGGCTATAAAATGCCTTTGAGTCCATGATCTGTTTCAATTAA AATGTTGAATCAAGGTAGACATCAATAGGCCCCGCCATTCTCAATTTGGGGTATTAGCTTCATTTCAAAC TCACTGTGAGTGGTGTATCTAATTTCTGGTTATAAAGTAGTCATAATCTTTGAAGCTATTTGAACAAAAC TTAGAACCATTTGGAATTATTTTCTGAAAAGAAAAAGGCTGTTTTACAAAATTATCTTCAACTTTCTACA GATAGATAAACTGATGAGGTTAATCAATGTGGATTAAAATATGTCTCCCGTTTTTATCCTCATTCCTCTC TCTCTCTCACACACACACACACACACACACACACCTTTTATTTTCTCCAGCCTCTGCCACAGTGTATAAT GCCCTATTGAGACGTGTAGGCGTGATGTGTAAACCGGATTAGCAGTATGAAAGAAAGACACACAATAAGC TGGAATTGTTTTACTTCCCTTTCATTTCTCATGCCTATATTTCTGATAAATTTGTTGCTCCAGCAGTGGG TCAAAGGGATCATGTTGCTCAGCTTCTTTTTCATGCAGGACCCAATAGCAGAGATCACTGAAATGAATGG TGTGCCTCCTAGCAAACGCAAAGCTTGATAGAGATATATTAGACAGGGAGAGGCGAGGAGAGGGAAGGAT GCAAAACATGTTCAAAGTCTGGGTGTTGTAGGAATACATCTCTATCCATGAGAGGAAAGCAATGTGGGTA AGAATATATTTGGAGAGAGAGGGATCAATGCAGGGGTCAATGCTCTGTTTTCTTTCAAGTTCATAGTAGG CTCTGAACATTCAGCAGTTGGTGACATGCTTAGCAAGAGAATACCAATAGCTTTTGGCAATACATAAAGT CTAATTCCCCTTTCAAGCTAGTATTTAGACCTGGAGTAATCAATGTGGAGATTTCTGGGACCTTCTCAGG ACACTCCCCTCTGCCGCTTTCCCCACCCCCAGCTCACTGTAAGCTCAAAAAATGCCAGTGCTCCCGGGTT TGTGCTGTAGACCCCTCATTTACTCCTTTGTGGAGTTAGGAGCAGCTTCCCATTAAAGGAGATCAGGGGT AATTAGCAGCATTATTTTGACAAGTTGGCTAGAGCTGTTCCCTTTCCTCCAGCCTGGGGAGGGGGTAAAT AAGGGGAGGAAACAGAAGGTGGAAGGGAGTAGGGGAGGGGAGTCAAGCCCAGTAGTTTTAAATTTTGTAG CTGCTGAATCTCCCCCCACCCCGTCCCCGACTTCCCTGAAACCTTTTAGACTCATTTTCTACCATCACCT TTTAAGAATATACAAAAGCTGCCAATGAGAAAATAGTAAGGCATTCTTAGGGAGCCAAGAAAATGTGGTG GATGGTGGCACATTGGCTTGAGTTGAGTCGACTCAACTCATATTCAAGGTACCTGCTTGGAACTGCTGAA GCCCTGCCTTGACCATCACTCACATCCTGTATCCTGGGCTCCCCATGCAGTAAAAGAATATTGCATCAAA TCCCCAATTCCTCTCTCCATCCGACCCTCTCAACAAAAATACTGTAGGACTTAAAATCATGTTTGCAATT CCTTGTATTTCTGGAAGAGTATTAAACTCAGTAGACAAAATTATAAATGGCCCCAGGGTCAAATTACTGG AATACATTAACCCCTTTATTCATTTATACTCTGCAAAACTTGCCAAATTACATTGGATTTTAAAGACTCA TTTGGTTTGATCTGAGAAACCAGTGAAAAGTTAAATCTCACTGTGGTTTTTCATAACTCCACCAAGTCTG GCTTCCACAATTGCTTACCATTGGAACATCCCAACACAAAGGGCAGATGTTTTATTTCATTGTCATCATT TGGATAATCTGATGTCATTTTTGAAATGTGTGTGGTGTGGCCATGGATATTTGTAGTATTGGAACAGAGA AGGGAGGAGATGTGAGGGAATCCGGAGAGCTTAAGGCATCTGCTTTGAAAACTACACACTCCAATGAGAA GTCTTGGATCATGACTGGGAGACCAAAATGACAATTTATGCATTGAGATGAACTTTACTTGGAAAGGGGA AATGGAACACTCAGCTGTTGCTTCATAAAGGCTGGCAACTCCTGCTGGCTGATAAGGCCCCAAGTTCTCA CTTATTTTTATTTGGTAACTGTCACAAGGGGTGCCAGAGGCAGAAGGGCCATTTAAAGGGACTGTCTTCC CGGAGGACACCTTAGCAGGTCTGGCTGCCCCAGTCTGCATCTCAGATCTGTGGAATCCTTGTGGTTAGTT GAAGTTAACAAACCCGGTGTGGCACAGCAGTCCCCTGCACAGGGCATGCATATTAAAGCCGACAATGCTT ACAAATGTAAATAAGGGCAGATTGATTAGGAACAACATTATCGCTGGGAATGTCGCACTCGCATGCATCA GCAATGAGGCAAATTGGGGGCAGCCTCAGCCCTGACCACCCAAGTCGAGCAGGCTTTTACACTGGCTCCT CTTCCCTTTCTTAAAACGTTACAGAAACAAGGCCAATTAGATCCTCAAAGTAATTCATCTCTAAGTATGA AAAAAGCAGACCACAGGGGAAGCGGCGGGTGGGGGGTGGGGAGATTAAGATAGCGCTCGTTAGAGCCGAG GCTCCGGAGTGCGTCCTGGAACCCACGGGTAGAATTTACAGGCCGGGACCATTGTCTGAGATGCTGAAAA GTTAACCCATCAAACAGCGGGCGAGGGGGCTCAGGGCACTGAAAGCTCCGGGGATCAATGTTCAAAACGT TTAGGAATTAAGTCAAACTAAGGGATATGGGCCTGAGTGGAAGAGGCTTTGCCACTGAAATGACGTGCAT GTGGCAGCCGCCGGAACCAGAGGACATGCAGCCGCGTGCGGAGAGTGAGGCGGATCCATTACGGGCACAC AGCTTACCATTTCCTTCCAGAATTCCTTCTTCCAAACAAGCTATACTGAAATCCCTCTAGTAAAAGATTG AGACGAAACACTAATAGTTTTGGGCCAAAACGTGGTGGAGAAGTTTGAAAAGACAAACATAGCAACGTGT CTTTGGCTATATGGTTCCTTGCCCTCCAGCAAGCTTGAAATATAAAAAGGCTAACATGCAAAACTAGGGG TACTACCCCCCTCCCCCAGTTTTTAAAAAGCAATTTCCAGAAGCAAACACACAATGGTTCGACTTGAAGT GTCGGCATAACCATTCAGTAAGAAAAGCTAGAATAGTAAACCTCTTTTCCTGTTTTGTGCTATTTATCAA ACCTAATAAACATCAGGATCGTACTCAAAGATGAAACTGGCAATGTGTGGAGCCGTCTGAGCTCTTTATC AACTCAGTGTCATTTTCCTCGCATGCTGCCCGCCTGCTTTCCGAGTTTCCGCAGCCCTTCCCTGAGGCAC TCACAAAATCACGTGCTCCTTAAGCGGTCTGAGTTTTGAATTTCCGCGCTGGCCCGGTGCTCAGGTCCCC CTCCGGATCCCGCGAACGCCCCCAAACACCTCCACCCCGTCTCCCTCTCTTCCTCGGGACATCCCGCCCT GACCCCGGCACCGCATACGGTTTGCGGGTTAGGGGGTCGGGGGAAGGGCCTCCCCCTGAAGCCGGGGAGG AGGAGAGGCTGGAGGGAAGGTGGCCAGGCTGGTGGGGGAGGGGAGATTGAGGGAGGGAGCGGGGCGAGGG AGGAAGGAGAAGGCGCAGGCCGAAGGAAGGAAGCGGGGAGGGGAAACCGCCGGGGAGGAAGGAAGGGGGC GGGGAGAGCCGGCGGACGGGCCCCCTGCGGGAGCCGCGTGGACCGCCCCGGTGGCCGGCGCGCCCCGCCG CAGCCCCCAGCGCGCCCGGGCAGCCAGCGCGGGGCCGCTGAATGGGCAGGGACTCGTGAGCGCGACCATT GGCCGGTCGCGGGGAGGCGGCGCGGGCATTGGGCAGCGTAAGGGGGCCGGTCCGCCTTCAGGAATGTACT ACGGCGCGTCCGGCACGTCCGTCCGCGCCGGCTGGGCGCGCGCCTCGCCTGGGCTCTCGGGAGACCGCGC TGGAGGCCCGGAGCCGGCCCGGCGCATCCGCCTCCCTACCTACTCTGCCCCGGCCGCGCGGGCGCGGGGA GTCCGGGAGCCGGGCGCGCGCGCGCACCGGGCCTCCTGGCGCGGGGTCACGTGGCCACCGGAGCTCCGCC TTCTCCCTGCTCCTCCCCCTTTCCCTCCATCTGGGTTTCTTTCTTTCCTTTCCTTTCTTTCTTCTTTTTT TTTCAATGAACATACACCGTGCGCATCTTAAAGCCACACCGCCCCATTTCACGACTTCACTAGACTTCTC GCTACTGCCAGTCCCTCTGCAGTTCAACCCCGTTTAAAAAAAAAAATAAAGTGAAGCAAATCAAGGGTTT GCGGGTCGGGTTCCTACCGCAGGGAGGAACGTAATAACTTGGAAACGTAAGAAAAACACATTCCACTTTC CGAAAACAAAAATTTTTTTAAATAAAAAGCCTAGTTGTGTAGACGTGTCTGGCTCCAGAATCCACCTCAA AGGGTCGCGTGTTTTCCCCCTCCGCGGGAAGCGAATCCCCGGGATGCCTTGGTGACACTGGACGCGGTGT CGGGACGAATCCTCGCGATCCGCGCACAGTTTGTTTTCAATGAATCCAGCATCGGGGCATTTATAATCTC CTACGTCATACTATTATTAAATATAACATGCATACCGAGTTTTGTAAAAAAAAATACTGACTATATAAAC ATCTGGTTAATAAAAAGGGGTGTACAAATGAACCCAAAATAATCAGGAAAACTTTACTCTCTCAAGGAAA CAATTCCGTTTCTCTAAGTTGTAAAAAAAGATTCTGTTGTTTCTCTTTTACTTATGTCACATTCGAGATT CAAATAAAAACGCCTCTGCCTCTACAAGACTGCTTCGGTGTCTGGATTCCACGTTTATAGAACACTGACT CCTTCAAACCAAGACTGTGTTTTTTTTTTTTTTAAGTTGGGGGGAGAAAGCGGCTGGGGGGCAGACGGAT TTTAAGAAAGATGGCTTTTCCCAACGTCCTTGCTTTCCTCTTTAACTTTCCATTCTGTTTATCTTAATGC GAGGCGTTGTTCCCTGCAAGAGCCTAAGTCTTCCCTTTAGTTATAAAAGAAAAGAGAAGAGGAAAAAAAA ATCTGGCACACACTGGCGCACTATCCAGCACGCTGTCATTATTGGTGCAGGCCTGGGAATGCGAGCCGGA CCTCCCAGTATTTGCTGCAGCTTGAGGCCAAGGTGCCTCTGAAAGGCTTTTCTTTGAGGAATTTCAGAAA TTGTTTAAGCGCTTAAAAAAATATTACATTTCCCCCCGTGTCTACCGCGAGGCAAATGTTCGTGTGTGTG CGTGCGCGCGCGTGTGTGCGCGCAAAGGCATCCCACAAAAAGAAGACACTGTTGAAAAGAAAAGGAATAA GAGAGAAAGGAGGGGGAGCATTCCTTAATGGAAGTATTGCATGCGAGAAGGTTGGCGCTCTCAGAGGCTG CCCCGAAGCCGAGGATGCACACACTGGGTTGCCTACCTGGGTGGTCTCTCTACTTTGGTGAGCTGTTGCT AAGCAGCTAATAATAGTCATGTTTGCTGAGTAATTTCTGCCCTCCGCGAGCCAATCGCGTCGCAGAAACC CAAGCCATCTGACAGCCCCGGGGGCGGGAGCTCCAGCCTTTTTCTCTTTCGCTCGCTCTCTCCCCCTCCA CCCCCTCCCCTCCCCTCCTCCTCTTCTTTCTCCAAATGGAGAGAGTTCTTTTTTTTCTTCTTCCATCTCA TCTATTGAATCAAGGAGCTGCTGCGGCCGCTGCCCGCTGCACACACACAGAGCGGAGTCCCCAGGTCCCG GGAGCGAGAGAGGCGCGCTGCACGGGGACAGAATGGTCCAGCGGGTTGCCGAGGAGCACAAGAAAGCAGA GTCCGGGACCGAGCAGCCACCGCGAACCCAGCAGCCAGAGCCCGAGCAGCCCGAGCAGCAGCTCCTGGAG CCGCCACCGCCAGCAGCAGCCACCGCGGGAGCAGCGGCAGCTGCGGCTGCCCGGGCCCGGCAGCGCTGAG ACCCGCCGGGCACCCTCGGACCCCGCGGCGGCGGCGGCTCTGCGCTTGCCCTCCGCGGCCGCTCGGGCGA CCCGGGAGGCGCCGAGAGAGCCAGCGCGGCCGGCGGGAGCAGCGGGGATTCGCTGGCTCTTTCTGCAGTG AAGGGGTCGCGGCGCGGGGCGGGGGGCGGGTAGGGGGAGTTGGGGACCGCAAGGAGTGCCGCGGAAGCGC CCGAAGGACAGGCTCGCTCGGCGCGCCGGCTCTCGCTCTTCCGCGAACTGGATGTGGGCAGCGGCGGCCG CAGAGACCTCGGGACCCCCGCGCAATGTGGCAATGGAAGGCGCAGGGTCTGACTCCCCGGCAGCGGCCGC GGCCGCAGCGGCAGCAGCGCCCGCCGTGTGAGCAGCAGCAGCGGCTGGTCTGTCAACCGGAGCCCGAGCC CGAGCAGCCTGCGGCCAGCAGCGTCCTCGCAAGCCGAGCGCCCAGGCGCGCCAGGAGCCCGCAGCAGCGG CAGCAGCGCGCCGGGCCGCCCGGGAAGCCTCCGTCCCCGCGGCGGCGGCGGCGGCGGCGGCAACATGGCC TCGGCTGGTAACGCCGCCGAGCCCCAGGACCGCGGCGGCGGCGGCAGCGGCTGTATCGGTGCCCCGGGAC GGCCGGCTGGAGGCGGGAGGCGCAGACGGACGGGGGGGCTGCGCCGTGCTGCCGCGCCGGACCGGGACTA TCTGCACCGGCCCAGCTACTGCGACGCCGCCTTCGCTCTGGAGCAGATTTCCAAGGTGCATTTCAGACTC TCTCCTCCCACTTTCTCTTCCCTCCTCTAACTCTTTGGGATCGCCCCCGCCACACACAAACACACACACT CTCTTCCTCTCTCTCTCACACACACACACACACTCACTCACACCTCTCCAGGAAAAGCAGCAGACAAATG GGGATTGAAAAATTCAAACCCTCCCTCTGGTCCTGGGAGGAAAGGGCTGTCTGAGGTCCGCAGGGGGTGG AGGTGTGTGTGTGTGCGTGTGTGTGTGTGTATACACACGCCCTCCCTGGTGTGCCTTTTCCGGAGCACTG GAAAGCCGTCCACGGCGGACCACCTCAAGGGCGGCCGCGGCACTGTCCTGCCCCGTGCCCCCTGCCCTGA ACTTCTTCCTCCTGCGCCCCTGCCCCTATTTGCAGCCTAAACTCCTGTACGGCTGCCACATTTCTTAACA TCTTGGAGGGGGAGGCGGAGTGGAGAGAGGCGGAGAGAGGAAGGGGGGAGGGAGCCGAAATAAAGGTGGT TTCCTTTTTTGGCAGCCAGTTTTGGTTTTGTTGAGCATGAAATCTCTGCTCCCTTAAAAAATTATTCTCG GAAAAAGATATCCCCCCCGTTTTCCAGGTTTTGAGCCGCCTCTCCTTAGGGCCTGGTCGGGGGAGGAAAA GTTGTAAACAAATTGCCACCTTAAATTCGCGGTGCGAGTCTGCGGAGCTGCCGGGTTCATTGTGTTTACG AGGCTCGCTGAAATGTGTGGAATCCAGGGAAGGCGAGCACCCAGACGGGGGCCCGCCGGGGCCGCGGCCA GCGCCGGGGAAATGCCGCGCCGGGGAGCAGCCTGCGCCGGCCTGAGCCCTTCCCTTTGCACTCGGCTGTT TTTTACGTTTAACCAGAAAGGAAGGGAGAGGAGGGAAAGATCCATGTGGCTGCCCTCTTCCGATCACAAA TATTGTCGTAAGTTGCAGCTGGCTGCCCCACTTCCTAATTCAGCTCACACAGCCTCTCCCCACGCTATGG AAATGCGTCGGGAGTGAACTCCGGCGGCCGCGCTCACCACGTGGATCCCCACTTACTACCATTCTCGGCG GGGGTCCAGTTGGGGGAACCCGCAATATGTTGTTCCAAAGAGCGCTCGCCCCTAGCGCCCGTCCCCGAGG GTGATGGACAGAGCAGGACTGGTTTGCTGGCTCCTGAACCTTGGGCTCCATCGCTGGGATTACGCAGCCC CTCCCTTCTCAGCTCTGGGGTGAATATTGTCTGTGTCGAGTGGTTTCTCTCCTCTCTACCTCGGCTTCCT CTTCTGTATTGCAGCCCCAGTGCCCCAAGTCGCTCAGGGATCCCGCGGGTGGGGGCGCCCTGATGTCCCC GAGGTGCAGCTCCCACGCTGCGGCCCGGCTTTATGACCGAGCCCCCCATGACGCTCAGATCCGCCGGGGC TGCAGTCTCGAGGGCGAGTCCGTGTGCCGCGGCCACCCGCGCCCCCACGGCTGTTGGGGGCTCACCGGGC GGGTGCGCGCAAGCGGGCGTGGGCGCGCGGGCCGCGACTCCCCGGCGCTCACTCCTCCCTTCTGCTTCGT CCCCAGGGGAAGGCTACTGGCCGGAAAGCGCCGCTGTGGCTGAGAGCGAAGTTTCAGAGACTCTTATTTA AACTGGGTTGTTACATTCAAAAAAACTGCGGCAAGTTCTTGGTTGTGGGCCTCCTCATATTTGGGGCCTT CGCGGTGGGATTAAAAGCAGCGAACCTCGAGACCAACGTGGAGGAGCTGTGGGTGGAAGGTAAGAGCGCC CGCCGCGGCGCCCGCGCCCCCGGCCCGGTCCCTCCTCGCGGTTGATAGAGATATTCGCCAGCGCACACCT AGAGCCTGGCTGCGGCCGGCGAAACCCCCTGCCCGCACCCGGGGGATTGTTTATTGTTTGGGCGCCTGGC CGGGAGCCAGGCCCGCCCGACAAAGGCCGCGCTGTAATCTACTCGGGGCGCTGCGCCGGCCGAGGTGTGG TGGGAGAGAGCGGCGGGGGCGGGACGGGGGCGCGGGGCCCCTCCGGGACGGACCACTCTGCGCGCCGGGG GCCCCGGGCCCGCCGCCGCTGCCGCTGTCCGCCTGGGCCGCGCCCCGAGAGGCGCCCCGGGGCTGGCCTC TCCCGGCCCCGCTCCGCGGCCCGGCTTTCTTCTCTCCCCCACCCCCACCCACCGCGTCCAAAGAAAAAGG AGTCGGGGAGAGCCAGAGGCCACCCCTCCGGCTGGCTGGAGTGTGCGCGCCCCCGGCGGCCGCGGCCGCC GCGCTGGGGAGGGCCGGGGGCGGGCGCAGCGCGGGGCTGCGGAGGCGGCGGCGTGTGTGGTCCTGTTTTT GGACAGCTTTCAACTCTGAGGGAAAAAAACATTTGTCTCAAGGTACAAAAAACGCGGGGTGGGGGTGGAA GGAGTGGAAAAAAAAATAGTAAGGCACAGACTGGAACGCATGTTTGCAAAGTAGATTAATGTTTCCTCGC GGGTGGGGGCTTTTTACATGGAATTATTCTGGGGGAAGGCTGCATTTTGCAGGCAAAGAAAAGAAATGTT TTAAGAACGCGGGGTTGAAGGGACCTCTCAGAGGGGTTCTGCCAGTCTTTTATCCACGTTCCTCAGTTTT GGGGTTCTTGAGACCTTAGCAAAGCAGTTGCAGATTTAAAATAGATATATATTTTTTCGAAGACAAACAT TTTTACATTATTTTGGTGACAAAGGTTTCAATTTTTTTCCCCCGCTGGTTTCTTATTTATCTTTTTGGCA AGTTCCAAATCCTGCTATTTGGAAACACTTTAACCCTAAACACCACTTTGGGCATCCCTTACCTTACAAG AGGGTAGTAGGGGAGGGTAGAGGTGACTAGGTAGATAATTCAAACCAAAATACCTGGAGCATTCCTCCGG ACAGCATGTGGAAGCTGAAGAGTTATGCGCATAATCGCTTCAGTGATCCCTTTCAGGATGCTGTTGGAGA CCTTGAAGAATATTTCCTTAATCTCTCCTTGTTTGTGAAGATTCAGCTTGCAGAGTTTTGCAAGCCTGGG GTGGAGTTGGAGTATTTAGTTGAGAAGTGACAATTAAAATAATAGTCTACATAATTAAGACAAAACATTC CTGCCTTAAGTAGTTTGGTAATTAATACAAAAGCGTTCTTTGGATTGAATCCATGGAGTAATTTACCTCA GTTCAGCGATTCAGTATCACTGGTAGATAAAAGAAGGGTTTTATCGAGCAGCTATTATGCTCCTAGCAAC AAGTTTCTTGAGCACCTATGATGTCCCTAGCACTGTGTTAAGCACCATAAGAGACTCAAGTGTGTGCGAC ACTGCACAATTTAAAACTATTAGAATTCGATGCATTTGGACTACATTTGGGTTCACAGCTGAAATGGGCT GTGAAAGTTACAAGAGGGTGGTAGGGGGTGGGGGGAGAGAACTGGAGACGGTAGGGGAAGGAGGGCATTT TAGGCATGGGCGGGACACCAGCAGGGGCCCCAGCTGAGGAGTTTGGAAGTGATGTGATTGGCTAGACTGT AGGGGCGCTGCCGTAGATTCTAGGACAGAATAGGGCATGAGGACAGGGAGGGCCGCTGCCGTAGATTCTT GGACAGAATAGGGCATGAGCACAGGGAGGGCCGGCTCATCCACCACTTGATCCAACCTGTATTTGTTGCC ATCGGATGAGGATGACAAAACGTGATTTTGTGGTGTTCTTAGCAAGAGTTTTCAGTGGACCTTTGACATG TTGAAGGAGATAGAATGTGATTTATTTTCTTAACATTGCATATTTCTGGAAATAACTTGCTTTCTGCATA ACACGACCCATTTCAAGTCCTGGAAGGAGATGCAGTGTGCTTCCTAGCAGTTTTATGGGAGCTGCCAGTT GTGTAGTGAGAGGGAGTAAAGTTTTTCTTTTTCAATGGACTGGATGAGGACACTTCTGAGGGGCACACTC ACTTTGCTTACTTTTGGCAGTTTCAGCATGACTCACTGGTCTTGGGCCAAATGTTATTTACTCAGTACTA ATACTGTCACTTGTTGAGCAACTGCCATGTACCAGGCATTTGTTATATATTATCGCATGCCTTACGATTC AATAAAATAGCTATTATTATCTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACGG AGTCTCGCTCTGTCGCCCAGGCCAGACTGCGGACTGCAGTGGCGCAATCTCGGCTCACTGCAAGCTCCAC TTCCTGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCGCCACCGCG CCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCTTGTTAGCCAGGATGGTCTCGATCTCC TGACCTCATGATCCACCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCGGC CCTATTTTGTTTTTATAACATGATAGTGGATGTAATGTCTTTATGATGAGGATTGTCCCATTTTACAGAT GGGAAACTATGGGTTGTCTGTTTGTCTCCAGGTCTACTTTGCCTACTAATGACATAAGTCACTTGTTCTG TTGCCCTGTCCTTGATCTCTCATTCATTCATTCATTCATTCATTCTGTGCTAGATTCTCCCCCTAGAGAA GAAGCGACAGTTTCATAAATGCAGATAGACCCAACTAGAGAGGTGACTATACAACAGTAGCCATATAGAT TTAATTTCATTTTCAAAGCAGAAGTGATTGTGTAGAGATCTTGTTTGTGACAGAGTGAGCTGAGTGTTCA CGTCAGCAGTAAGTAGTGTGAGCATTTGCATTCAGGAGTAAGATTTCCCTGCTGTCCTATACCTCAGTGG ACGTCCGTGAATTGAAGTGAGTAATAGCTCCACATTTAAGTTCATTTTGTGCATCAGTCTCATAGATAAA TTCCTCATCACTATCAGCAAAGAAATCTGTTAGATGCTGCTTTCTTGGTAGGTTGTTCTTAAGGTTCTAG ACATGAATTTTTATATGAACTGGGCATCAACAGAGTGCTTGCTACACAAACGAAATGGATAGAGGTAGCA TATTGCCCTAGTTAGAAAACAACAGAAGAGAGGAAAGTATGAGATTTTAAGGGGAGAGGGATGCTGAGGG ATAGTTTGGAAGAAGCTCCTTCTCCTGCGGTTTAAAATCACAGGAGCGTGTGTGTGTATGCACATTGTCT TATTCTGCATATCCTCCTATCTGCCAAAGGCATGTTAATGTTATCTTTTTAATACAGCCAGCAAATTAAA GGGATCCACTCGAAAGGCTGTGTCTTCAAATTGACTTTCATGCTTTGTTTAACATGCTGGGGAAATGTGG CTTTATAAAGAGTTGGCTTTATAAAGAGGGCAGAATACATCAGCCACAATGTGCAGACTAATATATGCTA GATGAGAAAGAGTCCGTGTGTGTGCATGCGCGTGTGTGTGCGTGTGTAGGAATTGGTGATAAGAATTATT GTATTCTGTTGTTAAAATGTCCATATAATGATTGCCTTTTAATAAACTGTCAATTATATGTTAAGATACC AGCTTGAGTTTTAGGGTTATAGTGTTTGCTAATCAAAATTGTCAAATCAGTTTCACATATGTGCGGAGTA ATGAGGTTTGATAGAGAATATGTTGACTGATGTAGTGGACATCTGCTGTTGCAGAAACACATGACCATGG CAGCAAGGTGGGGGAGAAACTAATTGTCATTGTATAAAAATAGAAGCGTTCATTCTGCACATGTTCTCAG TACCTACTCTGCACCACCATTGCAGAAAGCTCTCCAGAGAGATGTTGGTGAAAAGCCACAGTCTCTGCCC TCAGGGGAACTCCATCCAAACATTCAGCAGGTACACGGACTGGTGTGTGGGTAGTTAACATGAAGGACAG CAGTGCCAAGATGGCAGGAAAATCGGGGACATCTTCCAGGATGGCCTCAAGGGTGGAGGCCTGAGCTAGG CACAGGGGCTGGAGGGGAGAGGGTAGGGGGCATTCAGGGCAGAAGGAACAGCATAGGCAAAGGCTCAGAG AACAGGAATGTGGCCTCCTGGAGGGCAGCCTCCCTTTGTGGGTCGTTGAGGTTGGGTGGGAGCCTGGAAG CTGGGCTCGTCCCTCAGGGCCATTTCACAGAAGTCTCCCTGCTTGGCTGGGGGCTGTCAGCTCTTCCTAC TAGCCATCCCTGTCTCACGAGTGTGCTCACGTGTTGGCCTCTAGTGTTTTCCCTGGAGCCACGAATGCTT CACCTGGATCTCACCTTTCTGGGCACAGACTGGTGTTATTTTTAATCTTGCCTGTTTCTTTGTTGGTATT TCCTTTTTGTTAAGCAGTTTTAACCCATCTCCCTCAGTATCTATTTCTTTTCATATCAGCCCCCTCACTG CAGCCCTCCCTCAGAACAAGTTTCTTGTCAAGCTTCTCCAGCGATAGAACATTCATTTATTTCTTTGAGC TTTTTGTTTTTTCTAAAAGCTTGCCCAGCTCCTGGCCTCCTTTTCTGCAGAGGGCAGCAGCCTTGTAATG AATCCATATTGCTTTGGTGTTTGGATGTTAACATTGCTGCAGGCCAGCGTCAAGGAAGAAGGAGGCAAGT TGTGACTTTGACTTTTTTTTTTTTTTAAGAAAAATAGAAGAAATTGTTTTTTAAAATACATGCTTGGTAT GTGTAAGTGCTTTCAAGTTTGTACCTTGCTAGTGTTAATGCTTTCAGTGTTCTTGAACTCAGGCAATCAG TTGTAGGAGATAACTGAGTTTCACCACTCCTTCAATTTGGAGCAAGGTCCCTCAACCTCAGGACTATTGA CATTGGGGCTGGATCATCCTCTGTTGTTGGGGGCTGTTCTGTGCACTATAAGATGTTTAGCAGCATCCTG GTTTCTACCTACTAGATGCCAGTAGCACCCTCCCAGTTGTGACAACCAGAATGTTTCCAGTCATTGCCAG ATGTCACTGGGGGAGAGGGTGTCCCAAATCATCACGATTGAGACCCACTGGTTTAGATGATAAAAAGATT TTGATTGGAAGACTCATGCTGTGCAGATGGAAGACGTTTATTATGATGGAGTTGTGGCTACAATGCATTG CAGAGATGCAAGAGTATTAATCTTCTTTAAGATAACTCCCCCATCCCATTCCTGTATTTATAGACCCAGA TAACTATTTTTCTTAGAATGACATTAAATGTCAAAGAAAAACACCGTGATGGGTCGAAAGAGGAAAGAGG CCATGGAAGAAAGAAATAATTTATATTTGGGTACCTTTTGGTGGGGGGTATCTAAATTTGCAGAAAGACT GGTTGCACCTCAACCCCAGTAGCCTGAAGGTTTTTAGCATGGTTGACTTTCTGAAAAGCTTTAATAGAAG ACACCACTGCCTTTGTGCATATTGAAATAACAGCTCCTTCAGAAGCCCGGCTAGTGTGTGAACTCCTTGG TGGTCTCATTCTCCTCCAGATGTTTCTGTCACAAACCACTCCCCCTTGTCCCCCCAGGAGCCCTTGTGGA GCAGAACCAAGGGACAGCAAGGGACCAGTCCCAGCCAGAAGGGCAGAATGGATTCTGCTGTCACTGCCCT TCCACAGTGAGCACCTGGTTTCTTTTCTCTGGGGTTGCCATTGTGGGGGCATTTCACAAGGGACAGGAAG AAAAATGCAGCTCCTTTCTGCTCCCTGGACCCCCATACATGGTTTAGAAGGGAGAATATGTTTATAGGTA TTTATTAGTTTCTACTACTGGGTATGCACATTTAGGTGGAAGCAGTTGTGATATTTCTTTCATATTTGGA GAAAAACGATTGGAAATGAGAAGCCACCAATGATTGTTTAAAAAAGAACAAATAGCCCTCAGGTGTCTTC TACACAGGGCAGTTGACCCTGCGAATCCTCCCTATCTCTTTGCTGTCTGCCATTCTTGACCCTTCACCAA GTTGAGAGGACAGGTTGGGTAATGGGGTGTTTCAGATACATAGGATGCCGCTCAGAGGTTCCAGAAGATG ACAGCTTCCAGATGTATGAACAGCCTGATCCGTGTGTTTAGATTATGCACCACAGCTGATGCCGAGATTA ATGCTGGCTGGACAAGCCATGGGAGATTTGTCTGGTTTCCACAATGCCATGTTTATGTTTCATTTGAGTT TCTCCTTCAAAGCTGACCTGCCTGTGACCCTGGGCTCTGTCCACTCGGGCAAGCTGAAACTCGGGCAAGC TGAAACTCGTCTGCCCTGTTCTCCTGCTTGTATTGGGGTAGGGGAGAGTCACAATTGGGCGGAGAAAGGG GCGCTTTGGTGGCCGCCTTCTGCCTCACCATGCCAGCTATCTGCCCAGATTTAGCCCCTGATGAGTGTTC AGTTCTCCTCGGGGATGTGTTTCACTGTAAAAGGTTTTTTGGCTTTTAAAACAAATATGGAAATATTATA AAATAACTGTAAAGGGGACCAGATTTAATAGAAGCCACTTTGCATAAATGTAGTATTTTAACTTCTGGCA CTCTTTTGACACTATTTAGGGGGAGAAAAAGTTGAGGGAATTTCAGCTATGTCAGACACCCCCACATAAT AACCATGGCTGTGTCATCCTATTATAATACTATTAATGTTTCCTGTGCCCCTCGCTGGCTCCCAGAACCT CTGCTGCCTCCTCCCTCTCTCCCCTGCCCCCTTCCCTCCTGCCCCTTCTCCCGCCCACCCACTCTAACCT GCCCACGTCATTTCCTTCCAAGTGGATCTCTGCAGTTACTAGTGTGAACTCTGAAATGGTAGTAAGTCTG GCTAATCACAACCTAAGAGGAGGGAATGAGAACATTTATTATTTCAAGCCAGCTGTGGGAGATACTAGAT ACAGAGCTGCCATTTGCATCCTTGGCATTCTTATTTTGGTTAGGGTTGGTTCCAAGACCACACTCTTTGA TGGGCTCTTGGCAGAAGATGTGATTCCCCTGTTGAAGAATCATGACTTTTTTTAATGGACTGCTGAGGCA ACTTTAAAATCCATTGACAAGTTTCTTCAACCCATACCACACCGCCAGAGAGAGTGGGAAATAAGTCTTG GTCCCCTGTGCTTACCGTGGCGCATGGACAGTGGAAGAACTGGGTTCCCTAGCATTTCTGAGACAGTGAG TGGAGCACAAACCATGGCTTTCCCTCCCAGGTGCCCCACTTCAGGTCTTCCTTGCTTAGAACTCCCACCA AAGCCAGTGGGCACATGGAGCTTGGCTAGATTGAAGACGATGGAATTCCTTATCCAGATTTTGGCCGACT CTGAAGCTTTATGTGTTCCATCCTCACGAGAGGTCTTGGTTGACATCCAGAGACCAGAGGGCCTTGCTGG TGAGGGCACTTCTGCCTGCAGGAGGAGGAAGCTCTGCGGGATTCTCTCAGTGGGAACATTCCTTGAATAC ACAGATATAATCAGGGTCATCAAAATATAAACACTTCTGTTACTTTCTCTTCTAATCTTTGAATTTGGGT GCTTATGATAATACTCACTGGATTTTTTTTTTCTCTTTAAATTGGATTTAGGGCACTTTTTTTCCTTTAC ACTGCAATGTCTAATGCCTTCCGTACAGCAGAATACTGCCATTGAGAAACTGCTGGGCTGTGGTGGAGGA TTTTAGGAGCCTGGTGTACAGGAAGATGCGCCCCATCCTTAGTCCCTCCAGGAGGGAATATGACTGTTCC ATTTGGGGTTTAGAGCATGGCTGGAAAAACAGCTGTCATGTGTTAGGGAAACTGTATTGTTGGTGGGCAG TCAGATACCTGCTAATGAATGGCAAGTTTGTTGTTGGAGAGATTTATAATGTGGGGGCAGGACCTTATTT CTAATCCAGAAACCCAGGTGTGAGTTGGCCCAAATAGTCCACTCTGCATGTGGGTCCCATAATGCCACTG CTATGAAAGCAAGGCTAGTGAGAAGCAAGTCCCCATACCACAGCGCAAGCTTTATTTATTATTGTTCGGA TAAATGAAAAGAAGCAGTAGACTTACCCAATTTAGCAACCAAGATAGTTTTCAGTTATTAATGAGACATG TATAAAAGTAAGCAAAAGGAACTGGAAATGGGCTTTGTTAAGTCAATGTGCATGATTTTTTTTCCCCCTT AAATCATTGCTTAAGGGCTTCTGGCCCCTAGCTCAGGAATCCTGCCCAAAAATGCCAGATGTATTACACA GTCAAGTATTGCAATGTAAACACCACTCCGTGCCACGAGGCAGGGTGGTCCATCTCCTATTTAAGAAGAG TGCGAGATTGAGAGGATGGGGGGTGGGGGGGTAAACCCTCTGCTCTGTAGTGAGCCCAGTGGTGGTTGTG TCATTTGTGTTTTTGGCTGCACAGTCAAGATTTGAAACTACAAAACCCAGATAAACACATTGGAATGGCA AAGAATAGCAACTTGAATTGGGATGCCAAACAAATCAAGATGTGGCTTGGATAGTGTTGCTTCATTGGGT CAGATAAGTTTATAAAATGTGGGACAGAATGGAGGGTGGGGAGAGACAGGAAGAGCGCTCTTGTCACAGC AGCATCTTTAAGTTGCATGAGCATCCTGTTATTCATTTGCTGGTGGTTAAATGGAAAGGTGAGTGGAAGC GAGGCGGAGAGAGCCCGAGCCTCCAAGATGACCTCCTCCGTGAGAGGAAGCCCTCCCGGGTGGGTGCACC TTCCAAGCCTGGAAAAGCTGATGGGTTGCAAAGCCAGTCTGGTGTTCTGTGGCACTGAGGGATGTAGCCC ACGATATGTTCTGAAGTAAATGGCTTTCCAGTTTTCTCCTGCTTTCTGCATTTCTGAAGTAAGAAGTCTG CTAATGATGATTGTTCGGAGCTGAGAAAGTCACTGGCACTTTGGGCCACCCTCCGGTATAACGTGTCGTA CGATGCTGCCAGCAATGACAGGAAATTGGAGTACCCAAATATTACCTATCCTTCCAGATAGCCTAACATG AAGCAGCCCTGAGAGTGACTACACTCAGGGTTTTTAAAAATTAATACGAACATGTTTTGTGAGTTAGGAA GAAATAGGATTTCAGTTTGAATTTGCGGAATTGTTGAAATACCTGCGCCAATATTCTCCTGATTAAGAAA TTTATTCTACAGAGTGATCTGAGAAAACGGCTTTAAGAAATAGTGATGATAAAAACAGGAATTTTGAGAT GAAGGAAAATGTAGGCTTCTTGACTCCCTCTTTCTCCTCCCACCGCTGTTTTTTTTCCTTTTGTGAATTC TTCCACATTCCCACCCCCACTCCCTGATTTCCTCTGCTCCTTTACTGGGAAACCAGCAACCTTCACAAAA TAGACTCAAACATCACACAGCCTCTTTTTAAATAGAGGCTTTCTAAGAGAAAATAACAAAAGAATTTTTC CTAGCTGCCTAAGAAATTCTTTCTTCTTACTTTATTTTCCTCATGAGATTTACACATTGTTGTAATAAGT AAAAAATGATAAATATGATACCATCATTTTGGTCTACACATGATCCAGAAAAAAAAATTGCACATGTTTA ATACCTTGCTTAATTGCAAACAAAGCTTGCAATTTGAGAGAATTGGGATTAGGGCTAAATATCTATTAAC TGCTCTTTCTAGAGATTTGGGGACTAGGATGACCCTTTTTTTTTTCTTTTTTTTTTTTAATAGGCTACAG TTTCACATGGCTCCCAAAAGAAATCTCTCTCCCTTTTTGTTTCCCACACCAATTGATTTATCATTTTGCT TGCAAGCAGATCCAGAATGTTAGGGCAAGAACACACTCACTTTTTTCTCGTAACTTTTTTGTTGCGGACC GAAACCAGTTGACTTGAATAAATTTTTCTGAGGCCTGAATGTAGCCAGCAACGTGGAAAAATCTTGCCAT TCAGGGCCGTCTGAATGTACATTTCAGCCACACAGTAAGCTGCATTGGGAGGCGCTGGACTGCTAAATGC AACCATTTTTCGCAGCAGCGAGTTAGACAGGTGATTAGCATAATTAGCACCGAGCAGCTATACATATGGT AATGCTGAGTGTGTAAATGCCAGCTGCGGTGTAAAATTTATGTCAGGGGTCGGCAGGGCTGTGCGAAAGT ATTGTGTTCCAGCTGCAGGTCAGGGCCGCCAAAGCTTACCTCCTTTTCTCTTGTTGGTGAATACGCCAAA CAGAAGAGAAAGACAGAAATATAACAGATACGGCTTTGATGGGACAGCCCAGTTCTGTGCAAGAGGGACT GCTCTATAAAACACACACACTCACACACACTTGCAGAAATCCCATTACTTTCTGTAGAAATCGTGTGTGT ACTTCATGCAGGGTCCAGATGAGTGGGGCCGGGATGGAGGTAGGTAAATGATTCCCTGGGAGGAAAAAAT TCAGTCATTGAAGTTTTAAAAGGAGTTAAAAGTTCTGTTTTGTTTTTCTTCCCACCCATCCTTTTACCCC CCACACCATTCCCTCCACCACTCTCCTGCCCACATTGTCTTATTTCACATTAGATGGGGGGATATCCTTG CTGGATGGGATAGCATTGGTCCTTTAGAAGAGGAGGAACTAACCGTTCTGGAGGTGTTAGCCTTGAACAA AATATAAGGTTTCAGCAGTGCAACTCTTCCCAAACTGCTTGACTAGCTTTAGAAAGGGGCTAAAAAAAGC TTTTGTGGGCTTTTTGTTCTTCCTCTGGGTAGCTATACTTACTCGCCTACCTATACTTACTCCCCCTACC TCCACTGTCAGACCCACCAAATTCTTTATAGATTTAAAAAAAAAAAAAGAATCACATGGGTTTCTTGTTT GAAAGGATAGTCTTGAATGGCTCACATACTTTGAAATGCATGATGCGGGAATTTATTGCTATGATGAGTT TATACATTTTGCACTTGAGGTATTTTCTCTGCCACGCCCCCACCTCCACCCTTCCGTTTTTTGGTTGGTG GCTATAAGAAGTGGTGGTGTTGACAGAATATAGTTCACACCATGCTGACCCGGTGATGAAACTTCCTCAC GGCACCAGGGGGTCCTTATGTACTGGCCCCTAATCCAGCTAATCCTGATGGCAACAAAATCATGAAAGTG GCCCCCAGTGACGTGAGTCTCCCTGCACAGATGCAGAGGGAAGGAACAGTGCAGGAGATAAATGAGGCCA GCGTGGTATTCACCGGAGGCCAGGGAGCCTGCGTGCGAAGGTGGAGACTCGCATTGTCTTCTCCCCCATG TCGGCTCAAGTGGGAGGCCAATGAAGAGAGGCCCAGGCTGGATAATGGCAAGAAGACTGTTCAGAGCTGA GAGGTGATGTCAGCCCCACAGAAGCTGAGAGAAGGAAACTGGGGTTAATGTTATGCAATGCCTTGAGTGC TGTGATGGAGAGCCTGCCGTGGAAGCACTTGGGTTTTGTTGTTGTTGTTGGGTTTCTTTCTGTTTCTATT TTTTTAATGAAGACTTCAGGAGGTTTCAACTAAGCTTGATGAAAACACGCTGTGTTGGTTCCTGGGTTCT GCTGCCTGCTGCTGCTGGAGTGTGGCCTCTGAGCCAGCGCGCGCTCGTCATCACACCTCTGGGCCCGCCC ACTTCCTGCAGAGCGACGGGACCTGGGTGTGCATCTGCCTGCCTGTTGCGCTTGAGCGGCCTGGTTGCAC CTGAGGTTGTGGTAGAACCTGGGACAGTTCCCAGCTTGGAAAGTACGCTGTTCCGGATGGAAGACATTTC CGCCTGTGCTCTGCAGGAAGTCAGCAACGTTCTTGGGCCTGTCTCAGGTGGCGCGGTGCACAGCCCTCAT TTGCCAGTGTGGCAAGTAACCAATGAAGAAGGGGCCTCCTGGCAGATGCAGCGTCGTCTCGGGAACTCGT GGCTCCTTGGGAGCTGGTGGGAGCTGCGACAGGCAGCAGGTCCAGCGTGGGCAGAGTGCCGGGCTGACCT GATTGCATCTGACAGGGCGAGCAGGTCTGCGTCAGGGAAAGCCATTCAGAGGGAGCAGCCTGGGCAAGGC TGATAACAGATGGCACTGCCAGCAGCTGGTGGGGGCGGGGAAGCTTGCTTCCGGCGCATGCGCGTTGCAG AACCCCGCGCGAGCGCCTGCGCACTACCTGCGCCCAGCCTGCCACATGCCCCGTGCGGTCCCGTGCGGTT CCGTGGGCAGGTGGGGGTGTCCTTTTCTCGTTATGCTTTGGTGGTTGACCTCTCACTGGGCTCACTTCAT GAAGGCACATTCTCTTTGGGCTGATTGTAGCGTTTTTCCCATGGCAACACGCAGGGGCACAATCTCATAA GGAAAAAAACGGCCCAGAAACTTGGACAGCGGTTGGCTCCTCCTGAATAAAAGAGATGGGTGGGAGAGGA CTAAAATTCACAGCCCGTGAATTTTCAGCCAATTGCTCACATTACTGAATTTTCTTTTTTTTTTGTTTTT CGATTATAAAAAAGAGGCAGTGCTAATAATTTTGCAGTTACACCCGCTTAGAGATTTGTACTTTTTCGGC CTCACAGTAAGTAAATGCAACATTGAAAGGAGGACCTGAGCAACTAAAAGAAAAAGAAAATCTCTCTAGA GGCTGTTAGATAATTCATGGGATTAATCAAATGCAAATGCAACGCTTGCATATACACAGACCCTATTTTC CTAATTGGACTCTGAGTGGGTACTTTTCAGGCTGAAAGGGTCATTTGTTTTGACTGATTGACTTTTTGAG GCTTTGGGGGGAATTAATAACTTATACAGATGACTGCCTGTTCCCAAGGCTCTGTATTGAGACTGCGCAT TCATTTATTCATTCAGCACACTTGGTGTGCCATGCCCCTGGTGCCCCTCTGCGTCCCTCACATACGGAGG TGCATGGGCAGGACTTGAATTTTGTGGAAAATAACTTCGGTTGGTCCCTCAGATCATCTTTATGTGGATC ACAATAAGCTTTTGCTAAAAGGTTTTTGTGTGAATGACACAGAAGTTTCTTAAGCTCTGTGCAGAAGGCT GTGCTGAGGAGGGGCACAGCAGGGAAGCGTGATGAGGGAAACATCTCTTGTCTACAGTGGATTGGAATCA TATTGGCCTAGAAGTATGGGCCTCTGGGTCAGCTGGCATCCCACCTGAGCTAGCTAGCCTTTCTTCACTT TGGAAAGTTAAGCCTGGCTTGATTTGGGGATGAGAGGATCAGCAGAGCTTGATCAAAAACTTATTTGCAG AAGTGATGCTTCTTTTGCCTTTCAAAGAATTGGCTTAAGCCTTGGATTTCTGGAGAATAAGATGGCAGAA TTTGCAGGTAAAGAGGCTTAGGGCTGCATGTTCTCTGTGTGCCTTCATCTGCCCCCTCTAAGACAGGACT CTCTGGGGACCAGAAGGAAAATGAGGCCTGTCCACTGTGACCCAGGGAGCCCTACTGAAAAAAATGCATC TCCTCACTGGCTGAGAAAAGTCTTTGATGCAACATGGTTGTACTTTAAATAAAAATACGGATTATTGTCA TATTTCACGCATTCTAAAATTCTAGCTGTGAGCGTAATACAGGTTGAGTATCCCTTATACAAAATGTTTG GGACCAGAAGTGTATGGGATTTTGGATTTTTTTAAGGGGGGGTGATATTCACACATAAGCATGATGAGAA AGCTTGAGGATGGGACCCAACTCTAAACATGAAATTTGTTTATGTTTCAACTACTTTATGCATCTAGCCT GAAGGGAATTTTATACGATATTTTAAGATAATTGTGTGCCTGAAACAATGTTGGTGTATATTGAACTGTC TGAAAGCAAAGATGTCACTATCTCAGCCACCCATGTGGACAATCTGGTTGTGTGGCATTCCCATCCTTCC TGACTTAAAATTTATATGCTGCCGATAAGCAATCATTTTCTTAAACTAATTCACACCTACGTACTTACCA GTAAAAAAACCACGACATTCCATTAATGCAGTGAAAAAAATAATGTGTTCAGGGTACCCAAGCAGCACAA TAGCATCACCAGATACCTGCATCAGTGGCTAAACAACAGCAGCTTCCGGTCTCCACCTGCAATGCTGTGT TTTCACTGAGAGGTTACTGTACACCATGTTTTATTTTTTTAGGTGAGAAGAAACATCAGAAGCAGTTGAA GGATCAGGGAGTGGGTTGTGTAGGGGCGAGGAGACATCTGCTGGATGGCTTTTCAGAATGTTTCCTCCAG CATCACCGGCCTCATTAACAATAGTTTCTGTCTTAAGACGTCTCTCTTTGATTTTATGAATTGACATGAT TTCCTGTTTGGTTGTGAATGCACGATGCGTTAGTTTTCAATAAGCCCATCACACATTTTTACCAGGTCTG CTATAGTTAACTTTTTGTGCAGTTGTAACATGTCATCTTCATGGTTGTGAGCCTGTTTTGACTGTGACTG ATTACATGAGGTCAGATGTGGAATTTTCCACTTGGAGCATCATATTGGCACTCAGGAAGGTTTTGGAGCA TTTGAGACCTTCAGATTAGGGATGCTCAACCTGTCTAGTGTGCTCTGTGGAATTTGGCACTCCTAGGCTA CCTCCTGCTGTACTCATGTTCTCAGCTGGTGCTCAGAAACCATGAGGCTCGCAGGGTAGTTGGACTCTGG GTTAAAGGGTCAGTTCTGCCTCTTACTAATAAGGTGGGCAACCTTGGGCAAGCCACCCAAACTCTGCAGC TATGCCCCCTCCCCTGTAACATCAGGACAGTGAAACAATGCTCTGTGACAAAGGCATGGGTGAACTGACA CTTGCTCCGCTCTTGGGTAAGGGTCTGGGAAATTTCACACACATTGTCAGCTAAGGCTCTCACAGTCCTG TGAGGTTCATCACAGCATTTGTTATCCCTGTTATCCTCAGCAACCAGGAAAGGTGGCTGAGGCTCAGCTG TGTCAGGGACTTGTCCTAGATCTCTCTGCCACTAGTGGCAATGCTGGGGTCTTCCGGTTTCCATTCTCAC TGCCTGTCTGGTACAGCTGGCCCCAGCTTGATGGAGGAGCAGCAATGATCAAAATATTTCCAAAGACGTA AAGAATATGGTCTCAAAGGGCTTTGCAAATGGAAAGCACCACCCAAGTATAAAACGTTATTTTGTGTCTC AGGATCCTGAGATAATGATTTTTCTTGAGTCTTGTTCAGAGGGGTTGTTATTTTATTGTTAATATAAAAG GACTTCAGAATATGATGAAGATGCATATGATTATTTTTATAGTTTATTAGTATTATTGATACATAATACT GTATATATTTGTGGTGTACATGTGATGTTTTGATATAAGCATATGATGTGTAATGATCAGATGAGGGTAA TTGGAATGTCCATCACCTCAAACACATTCATCATTTTTTTGTGTTGAGAACATTCTAAATCTTCTCTTCT AGCTATTTTGAAATATACAGTGTATTGTTGTTAACTGTAGTCTCCCTACTATGCTATGGAACACTAGAAT GTATTCTTTCTACTTAACTGTATGTTGGTACTCATTAACCCACCTCTCTTCATTTCCCCTCTCATTCTTC CCAGCCTCTGATAACCCTCATTCTACTCTCTAAGTCCATCAGATTAATCTTTTTTACCTCTCATATATGA GTGAGTACAGAGATGCCTATTTTTTTTTGCATTGAGTTTGTTTTTAATTCATATCTCTACCAAGTAGCTC TCATATCTATCTTTCTTTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTCACATAGAAGGTTTT GTTTTTCTGGGTTTTGTTTTGTTTTGAAGTGGGGTCTCATTCTATTGCCCAGGCTGGAGTGCAGTGACAC AGTCACAGTGCACTGCACCCCCCAACTCCTGGGCTCAAGCGATCCTCACACTTCAGCCTCTGAAGTAGCT AGAACTAAAGGCAGCCTCCACTACTCCACAGCTATTTCTTTAACTTTTTATTTGTAGAGATAAATACGTT TATCTGTGTTGCCCAGGCTGGTCTCGACTCCTGGCCTTAAGTGATCCTTCCACCTTGGCCTCCCAAAGTG CTGGGATTACAGGCATGAGCCACCATGTCCAACCATAGAAGCTTTTAATTATACTCTTTCATTGTAGAAA AATTGATAGAAATAAACTCAAAAAAGCAAAGCGGGTAAATATTATCCATAGTCCGGCCAGGTGCAGTGGC TCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACAAGGTCAGGAGATCGAGACCAT CCTGGCTAACACAGTGAAACCCCATCTCTACTAAAAATACAAAAAAAATTAGCCAGGCCTGGTGGCGGGC GCCTGTAGTCCCAGCTACTTGGGAGGCTTAGGCAGGAGAATGGCGTGAACCCTGGAGGCAGAGCTTGCAG TGAGCTGAGATGGGGCCACTGCACTCCAGCCTGGGCGACAGAGCAAGACTCCGTCACAAAAAAAAAAAAA AAATTATCCATAGCCTACCACACAGCAAAAATGGCTATTAACTTGGTTCCCTATGCCTACATCTACATAA CAGATACTAGATTTAATAGTTATTTTCTTCTGCACTATTTCACGAACATTAGATTATTTTAAAAATATGT TAGGACTTTGATCCTGACAGTGGAAAAAAGTCATGCCTGAAATCCCAGCACTTTGGGAGGCCAAGGCAGG AGGATTACTTAAGCTGAGGAGTTTGAGACCAGCTTGGGCAACATAGTGAGGCCCCCGTATCTACCCAAAA AAATGAAAAGTTAGCTGGGCATGGTGGTGTGTGCCTGTAGTTGGAGTTATCTGGGGTATTAGGGGAGGAG GATCGCTTAAGCCCAGGAGGTTGAGGCTGCGGTGAGCAGTGATTGTGCCACTGCACTCCAGCCTGGGCAA CAGAGCAAGACCTTGTCTTTAAATAAAAGAAAAAGAAGGGGGAAACCTATTTCTCCAAGACCATGACCTT CATCTCAGTCATCTAAAATGGGTTCTGTGGGACTTCCTGAGCTCAAAGCTTCACACTTAGGGATGATAAG GAAGACAGCAAGATAATGAACAGCTTTCAGCTGTCATTCAGCAGTGATTTAGGATAGGCGTTTGCTAGGG TAGCAAATGTCAGACGAGTCAGTAAAATTGCTCTATCCTGAAGGGTTTCTGTTTCTGGCAGCTTGCTCCA GAGTGCCTTGGGTCAATACTGATGTCAGAATATATGAGTGTCGTGCACTTTATGACACAGTTATACCCGA GAGGGAGCTGATTCTACCAGTTCACATGGTGAATGACACAAGACTTAATTATGGTCTCACCAAGCTCCGC CACACTTGCCTCCCTTCTCTCCCTGCAACAAGCCAAACCTGAGGGCTTTGCAGTTGCTGGTTCTTCTACC CAGAACGCTGTTTCTCCAGCTCTTCAAAGTCACCTAAATGTTGTTTCCCTTTAGGTCTTCCCTGCTATCC CATTTGAAATATCTTTTCCCCTTCCCCACTACCCAACATGGCATCACCATCTTCGTTTTCTGCATCACAC TTGTGCTATGAAGGTATCTTATTGTTTTGCTTGGCTGTTGCCTGTTCCCTTCACTGACCAGCATGCCTCT TGGAGAGAGACTACGCTGACTGGTTTCGTCCACCACATCCCCACTGCCTGGTCAAAGTACCCACCCACCC ACCCACAAATGCTTGCTGGATGAATGAATCATGTTACAGCTATTGGTCAGATAAAATGGGTGGCAACTAA ACTTCATTAACGTTTTTGAATCATTTTGCAAAACATTCATATTTGGTTAAATATAAGATGAAATATTAGA TAAAATATAACCATATAATATGTAAAAGTGAATTGCATTTAATAGTATATATGGCATAGGTGGTTGAGAA AACCGTAGACTTCAGAGTCTCAACTCTAGTTGCTTGGCCACCCTATCATGATAGTCTTAGTTGAAACATC ACATTGGCAAAATATTTGTGTTCATCATTAGAGCAAAGAGATGGGGGAGCGACAGGTTTTCCAATTCCAG AGAAAGGACAAATCTATACCTTTATTAAAATGTTTATGTAAATATACATCTTAAAACATCTAAAAAGGGG ACATGATGGAGACCCTGAGGTACATTTTATATCTTGTAGAAAATAAATGCCATTTCTGAAACACCCTGTG ATAAAATAACTGCTCCATTATGAGGTTGGTCTGGAAGAGTCTGGTAAAAATTTCTTAGCAGCACAAACTT TGTGTTTGGTTTTGCCATTTTTGTGCACACTGCACTCTCAGGTCACTTCGAGGATTATATAGTTAACAGG CGGCTGCTCTGCCAAGGCTCGAGGGGCAGAATCTTGCTGAAGCCAGGCTGTCTGTCATGGACTGCTCCTC ACTATAACGGCACCTAGGTCACCATAATAAGGGTGGGGGGTGTGCTTTGTTGCTGCTGTTTTTTAATTTC ATGGGTTTAAGTCACCTGATATGTTAAGCTTCAGTAAAGGTGCAGGAGGTGCAACTTTGTAATCAGAATG AAAAACCACGTGCATGCTGATGTTCGAGGAGGCAGTAACAATGGGAATGATTTCTGGGTTTGTGGCATTA GATGTGATAACACAAAGAAAGGGTGAGCAAAAGCTGCATTGAGCTCCTTGGTGGGCAGCTCTGCAGCTGT GACCTCTGGACTCATAACTGGCTTTTTAGCCTCATACAGCTTCTGCACTTCTAGGGGATGTGGGCTGGCT CAAATTCAGTTAATTGGTTGGAAGTCTGCGTGGTGTTAAGTACTGTGCTTTCTGCTAGAGTGAGCAAGCC CCTGCCTTCAGGCAGCTTTCCCAGGGCTTGCAGAAAAGGCCAGCCGAGTAGGTAGATGCTTCTCTGTGCA AGTTGTTTCCCAGTGTTTTCCTGTGATTTTTCCTTAACTTCACATTGATGGCAAGGCCCTCGGCAATGCC CCCTGGCATTTTTCAAAGTTTTCTGCACACAGAAGTCTTATTCCTTTTTATTAACCAACTGATATATTCC TCCCTCCTTCCCGACCCCACACGCAGTATGTTAAACCTCACCTCACGGAGCTCCTGGCCTTGGCATCCGC GTGGACCTGCACAGAGGGTCCTGCCAGGCGGTGAATTTGTACTGGTTTTCCTAATGAGGGCATTATTTGC TTTTTAGCCTGCCCCCTTGTTTATAAAATATGCCAAGAGAACTAAACAACCCGCTGTTCCCAGTCCTTAT TTACTTGTCCAAACCAAATGTTTATGTCCTTGAATACTAAACTTGAAGAAAAAGGATTCCTCCTCGTGGG AAAGCTATGATCACTGAGTTTTTTTCTAAACTGTCGCTGCAGGCCTGCTTTTCAGTCAACATGCAACTTA TCAATGACTTTAGGAACAATTCAGACCCGCTTCCTTTGCCCTAGACTGTGGAGTGGGGGAGCTCTAGGTT CCTGGGTCTGTAACTATTAGTATCTCCCTGAGACACCTCCCAGCCCAGGTGCAGCATTCGGAGCTTGGCT TGGCCCAGAACCGTTCATTGAACATAACCTTGGGCCTAAGGATGTAAAAAGGAGAGGAAGAGAAAAGGCA TTTGGCAGTCACAGTGTTGATGGTTTTCTTTGGTCACCTGCTCCTGCGCTGGCTTTGGGCATACCCCGTG CTGGCCAGCTTGCTGGAAAGCTGGGTTGGTGTGAGGCAGGACTTCTCGGCCTGGGCAGCAGGTTCAGGGT CACCTGGGGTGCTTCCGGAAAACAGGCTGCTCACCCCCAGCTGACTGAGAACCTGGCACCTGTGTTTTCT GGATGCTGACCAGGTGCGTCTGATGGAACCAGGTTCCAGGGACTGCCCATGATGGCTGTGGCTGATACAG TTTGTTCCTCTCAATTGGGATTTCCCCATGGGCATCTGACTTGAATCACTTTATTTATCTTCTCCTGGCA AGTTTTGTGCTGAACACACACTGGCCACCTTTCCTTGTTTCTTTTTCCACAGAGGAGAAACATTTCCTTG TTACCTTTGCCAGTTTACTTAGGAGAAGAGTGTAAATTGAAGCCATTTATCTTGAAATCTGCTGCAGGGG CGCATTGTTTATACAAGTGAAAGAAATTGTAACAGGGTTATTTGGTCTGGTCTGCAAGGAAAAGGTGTCT CAAGTTTTCCTTTCTGCCCCCCACTTTCGTCACACAGTGTATTAGTTAGAATTAGGTTTGTGTCTGTGAC AGGCGGGACAGCCATTAATGGGCTTAGTGAGTATTTTTTATGTTTACTATTGGTGAAGTTAACATTGCCA TTAATAAAGTGAATGTTACTGCTCACACATCAGCCAGTCTCATGACTAGAGTTCATCTATTGTGTATCCT ATGGCAGGTAGTCAGATAACAGATAAAACATGAGTTTGCAGTGATTTTGCTATTCTAATTAAACCTGTAC ATATTTGTCAGTTGGAGGACGAGTAAGTCGTGAATTAAATTATACTCGCCAGAAGATTGGAGAAGAGGCT ATGTTTAATCCTCAACTCATGATACAGACCCCTAAAGAAGAAGGTGCTAATGTCCTGACCACAGAAGCGC TCCTACAACACCTGGACTCGGCACTCCAGGCCAGCCGTGTCCATGTATACATGTACAACAGGTAAGGCCC GCCGCGTCCACCTACTAATGAGCAGCAGGTAAGGCGGTGGGAGAAGGCTGCTGGTTTAGGCCCCGTTATT TTAGTAAATGAAGTTGCCCTGGAAATGCACCTGGAGTATTAGTTCAAATAGCTTTGCAATGAAAGGATTT TTTTCATCTTGATTTATCGTTTCTCGAGTTTGGTAACAAAGCAAGTGCATTACTTGATAATGTATTGCCA GTAAGTATCTTGGCACTGTCCCCAAAAGAGGATGACGCTGAGCCACTTGGGGACTATACACCCAGGCTGT AAGATGTTTCATTGCTTAAGAGATTTTTGGAGAGTGATATTTTGAATTGCCCTTGCTGAACTTAAAAACA ATGCGAAAAAGAAGAGCTGCTTCTTGTGACTTTGTACTCTTAGTTGTTTTGTGTCACACAGCACGTTGGG GGCTGAGCCACCATGGGAATTGTTGCTGACACCTTTTTATTTATTTTTTTGAGACAGAGCCTCACTCTGT TGCCCAGGCTGGAGTGCAGTGATGTAATCTCGGCTCACTGCAACCTCTGCCTCCCGGGTTTAAGCGATTC TCATGCCTCAGCTTCCCAAGGAGCTGGGGCTAGAGGCGCCCACCACCACACCTGGCTAATTTTTGTATTT TCAGTAGAGATGGGGTTTCACCATTTTGGCCAGGCTAGTCTCGAACTCCTGACCTCAAGTGATCCGCCTG CCTCAGCCTCCCAAAGTGCTGGGGTTACAAGCGTGAGCCACCATGCCTGGCCCGCTGACACCTTTTTAAA AAGTCATGTTTTAGCATCGTATTGCTAATTTCACAATGCTGTGAGTAGAGTAAAGCATTAGGAAGAGTTC AAAACTCGGTCCTTTTTCTTATGTATCTAGACTGTTGGTTACTACAGGGCAGGGGCCACCTCTTGTCTGT TTTCACCCCAGCATTGAGAACAGAGTGGGCATTCAGTTTGTTGATTGCTTTTGAGGTTGGCATCACTAAA CCCCATTTCCAGGGGACCTCTGAGTTGATGTCACCCAACCCCATCACCTCCCCTAGGCTTTCAGCACCTC TTCACTGAGGCCTTTGTTAGTACTGTTTATTTTTCCTGGAAGAGGTGAGGAAGTAGCAGTATAGGCATAT TCAGCAGCCAGGGAGAACCAAAGAAGAGAATAAAATTAAGATTTTTCTTGTCCCTTCTCTAACCTCTGCT TACATTCCAGCTCGACAGGATCCTAGGGACAAGCACAGCCAGGGTCGAGTCACATGTCTTTGGCACATTC TTGTTTGTTTATCTGTAACCTGGGCTTATGGTCATGTGTGCTCGTATCCTTCATGGTTCCCAGAACAAGA CCAGATACATGAATGCAAGGGCCTTAGAAAATGTAAAATCATGTTTCTGCCAGGCAAACTTGCCCTGTTG GTCTGTAACAAGTATTGTAGGGAAGCAACTACCTGGTACAGTTTTGCAGAATGTGAAGTGGCATCCCTGT GGGGAGCCAGGTTGTCCTGGGGCCACTGCAAGCATGGCCAATGCATTCTTAGTGTTTGTCACCTACATGC TTCAGGAGAAGATGTGAGGGTCTGTGCCATTAAATTACACTCTTAAGCTGAGATGGGTCCAGAGTAATTT TATGCATTGGAATGAACTTTAAGAACATGTAGTTCAACCCATCCCATGTTTTAGGTGAGAAAACTGGGAA TTAGACTAATTAGAGCATTTGTCCAAGTTCATGCAGTTATGAAATGAGAGAGCCAGGTTTCAAAGCCTTT TTCTGGCTTCAAGCCCATTCATTTTTCTAATGCACAATGATGTCCTTCTCAAGTGTAAATGAGAGTTGAT CAAGTAATATAAAGTGAGAACCTACTCATGCCGGATAGTCTATGTTGATGCTGTATAGAATTAAAATATA AATATGTCCATGGATGTGTGGCTAGGTGGAGGATGGCGGAGATATGGGTAAGTTAGGCACAGCTCTCAAA GAGAGGAAAGACATCAGTATAGATAGACATGGACAAAGGAAACGTGGGCGGTCCCCATGACAGCTGCGCC AGGTTTCAGCAGGAGATCTGCCCAGCCAGGGCTCTAGAGTTCAGGAGAAGGGGGTCATTTTCAACAAGCT TAACATGGGGGTGACATTTCAACAGGGCGCTGAGAGACAGGAAGGCACAGGGAAGAGGACACAGTAAGCT CCTTGGGTGAAGACAGGCCTCCCTTAGGAGGCCAAGAATAGAGCAGTTGGGAGGGAAGTTTTTACTGTGT TTCTTTCTTTTTTTTTTTTTTTTTTCCTTCCCTTGGACTTTTCCATCCCCACTCTTCCAGATTTTCTTTT TTTTTTCGTTAGACTGATCTCCCTAACACACCTGGAAAGATATGGGCTTATATAACACTTTTCTAGAGAC AATAAAACTCCCGATTAATTCTTTTTTTTTTGAGAGATAGGGTCTTGCTTATCTAGGCTGGAGTGCAGTG GAGCAATCACAGCTTACTGCAGCCTCGAACTCCTGGGCTCAAGTGATCCTCCACCTCTGCCTCCCGAGTA GCTGGGACTATATATGTGTGGCACCACGCCTGGCAATTTTTTTTTTCATTTTTTTGTAGAGATAGAGTCA CTCTCTGTCACCCAGGCTGGAGGGCAGTGGCATAATCACAGCTCACTGCCTCAGCCTTCCAGGATCAAGT AATTTTCTTGTCTGTATAGCTGAGATGACAGGCATGCACCACTGCGCCCAGCTAATTTTTAAAGTTTATT TATTTATTTATTCATTCATTCATTTCATTCATTCATTATAGAGATAGGGTCTCACTTTGCTGCCCAGGCT GATTTCAAACTCCTGGCTTCACGCTGTCCTCCTGCCTGCACCTCCCAAAGTGCTGGGATTACAGGCGTGA GCTGCAGCACCCAGCACTAAATTAATTCTTGATCTGTATATTTATTCACATTTCTGTAAGATAGGAATAG AAGAGACTGTGAAGTTAGAATTTGACCCACCTGGCACATGTTGTTGTTTATAATATTAATGGTTAAGAGC AGGAGAGTTCATTTTGAATACTACCTATTAAGGACATGATCTGCCAGTAAAACATCTCCGCACCTGAGTA TGTGTCAATACTTTGCAAACCTAATTTAATCCCCGCCTATTTTGAATTTATGATAATTCAGCTGGGCTGC CCTGAAGTTGTTTAATGTATGTAGAAAAGCAGATTAATGGTGTAAACAAGATTATTGGGAGAACACTTAA GAAAACAAGACTTTTCAAGTACTTTGGTAGCATTCATTTACATAAACACCCTACATGTTAATTACGATTG AGTATTATCTATTCATTAAAGCAAGCTTGCTGGGTCTCTACTTGGCAAAAGCTCTGCTCGTTTTGACAGA TGCTTAAAAGTGATCGAAATTGCAGTTCTTTTTATATGTTCTATCATTTCGAATTTGCACTAATTTTCTT ATTACAGTGAGAAATTTTTGTCTCTGCTTTTCATTTTATTAGGCAGTGGAAATTGGAACATTTGTGTTAC AAATCAGGAGAGCTTATCACAGAAACAGGTTACATGGATCAGGTATATTTTCTTCTTGTTGGCAAAAATT TCTCAGGAACACCCCAGTAGTGTGCCTTAACCTAACGCATGGCCTCTTCTTTTTAACTTTGACAGATAAT AGAATATCTTTACCCTTGTTTGATTATTACACCTTTGGACTGCTTCTGGGAAGGGGCGAAATTACAGTCT GGGACAGCATACCTCCTGTAAGTGTGTGATCATGCTTTCTGATGTCTGTGACTTCTCTAGGACTCAGTGT TTCTAATGTTGCTTATCATTGTTTGTTCCATTTCAGTTTTGAACAAGAAATAAAAACATTGAAATTCCAT GTGCATTTTTTGAGTGAATAGTCGGGGGAGAGGGGATTTCAGCAGAATGTTTTTTCTCTTTTCAAAAAAC AATTCTGTAGGCGTCATTAAATTTCATTCACTTTTACCAACCTATTTATATGCAAATAAAATGCAAATTA TTGCAGAGTACGTGTGATTTTTTAACTCTTTAAAATGTTCGTAGTTTCGAAGACGAGGCATTTAGACACT TATTTTTTAAGGAGAGACTTTATTAGTGAGTGGGTTCACATCAGAATGAAATATTTTGAGTTTGAGATCT TCCTGTGAAGTAAAAAGCTAACCTTTCTTTAGATCACACTAATGGCATTTAAGGGGGAAATCCACTATCT GTGAAGGCCACAGTAGGGAATGTTTCACCGTTTAGCAGTTGGATATTATATATACCGCATCATTTAGAGA ATAATTGTTAATCAGCATAGACATTTTCAGTTAATTATGCAAGAGTGAGAGCTTGGGTTATTGTTTCTGT CCTGGCTTGCACATATCTGCAAAAGCAATTTGCAGTGGCCATCCCCTGACCTTCAGTGTACAGTTTTAGA TGGGAAATAAGGGGTTTTGTGTTTTCTGGTTGGGAGATTCCGAATAATGACTTCAGCCTGGTTAAGCAGC TACAGTGTGGTTTGAACCACATAACAGGCAGCCAAAAGCCTTTCTGGTCTGTCAACAGCACAGATTCAAA AGTGAGTGTGGGGGGAAGTGGCTGTGATGGTGGTGATGGCAGAGGCTGCAGGGGGCTTGCCCATTCCATT GCCAGGCTGTCAGAGAGCGCTCATAAGTATGGGATTGTTAAAGGTAGCAGAGATCAAATATTTTGATTGA TGACATTTACAAAGTATTTATTTGGCTGCCAAGTGCTAATTTGATATTGTGACGCCCTCTTTTTTAAAAA AAAAAAAATTTAATTTTGGATCTGTCTTTTTGGCTAATTTTGTATGTAGATATTAAATATACAATATCAG CAATTAAAGATTATTCAGTGCCCTCATTAACTTATGAGTCCTCTCTCTGCTTAGCATCTTCAGTCATGAA TTATTTTCCTGACCTAAGTTTTTATGCAGATATGCTGGAAAGGAGCATTTGTTTTGATGCCAGAGTCCCA GAACTGCAGCATTGCCAGGAACCTCCTACAAGGTGGATGCAGTGGGCGCAGCCGTGTTACTTTACGATGC GTTTAGAAGGCTCTTTTCATGGTCTCGTCTCCTAATTTCTTTTGCAGAGGTAAACCTCCTTTGCGGTGGA CAAACTTCGACCCTTTGGAATTCCTGGAAGAGTTAAAGAAAATAAACTATCAAGTGGACAGCTGGGAGGA AATGCTGAATAAGGCTGAGGTTGGTCATGGTTACATGGACCGCCCCTGCCTCAATCCGGCCGATCCAGAC TGCCCCGCCACAGCCCCCAACAAAAATTCAACCAAAGTGAGTACCAGCAGTGAGCGCTCTCAGAAGGGTG GAGAGCAAAACACTTTTTTGTGTCCATTCATCGTTCACTTTATTATTTTCATTTTTAACATTTCATTCTC CATGATCGTCTTTGTCTATGGAACTAAGTTTATTTATAGAGCTAAATTTTGCTGTAAGATTTGCCATACA CCTCCCATTAGCCTTGCTATTAATGTTCTCTCTGAAACACACAAGCCCTTAATGCACTGGATTTTAACAA GGCATGTGACCTGCCTACTAATTCCCATAATTATGTGGCTGTCTTTTTATTTTAGCCTCTTGATATGGCC CTTGTTTTGAATGGTGGATGTCATGGCTTATCCAGAAAGTATATGCACTGGCAGGAGGAGTTGATTGTGG GTGGCACAGTCAAGAACAGCACTGGAAAACTCGTCAGGTAAGCCAGCTCCCGAGGACAATCTATGCCCTG TAGTCTTCTTCCTTTCCTCAAAAGCCACTTCCCTCCTGACATCGGCAAGTGTATTTGTATTAATACTTAA ACCGTTATCCTCGCTAGCCAGGTGGCGTCATAGAATATTAAGAAATAGTAGCAGACTGCAACAGCTTGAA AAAGCACCTTGTGGGGAATTTTTCAAGAATGGATTTGTAGTTTTCATCAGGACCATAGTTCCTGACTATA GGGTTTAAGGAGATCTGCCCATTAGGTAGAGAATGGGAGCAGGTGTAAAGTAGGCCGGGACACACTGGTC AGAGAGAGTTGGTGGTGCGAGCTGCACAGTGTCATAGACTGTTAGCAAAAGATGGAGAGCCAGCGGCTCA ATAAGAATTATCCTTTGTGCACTTGTGGACTCTGGTCAGTCAGGTGTCTGGCGTTTCGTGTAAGATTTCT CCCTTGGGAACGCCACCGTCTGGGATTTCTGCACAGCAAGTATGCGTCACTGAGCCCGGTGTATCTGTTC AAGCTATCTGCTCCTCTCCCCTTCCTGTTTCATGGAATGGAAACTGTGAAAGGAAATTGCCTATTAATTT AATTTTGGGGTATATCTGTAAAAGGTTTGTAAGGTTATACCTTTAATATGGTACATCAATCTATTAAATA AAATAACCATCCTGGTCCCATTTTAATGGAAACATGTGCTCACAGAGAAGGAAAAGAATTGCAGCCAGTG AGTTGGGGGAGCTGGCTGGGGATTTGAGGCAGTGGAAACTGCTTCCTGGGAATACTGATGATGTGCCTTC CCTTGGACTGTGCTGCAGCGCCCATGCCCTGCAGACCATGTTCCAGTTAATGACTCCCAAGCAAATGTAC GAGCACTTCAAGGGGTACGAGTATGTCTCACACATCAACTGGAACGAGGACAAAGCGGCAGCCATCCTGG AGGCCTGGCAGAGGACATATGTGGAGGTAAACCCACCTTCGAATCGGCGTGCAGACTCGCTGGTTATGCA ATTCTTCATTTTCACCATTATTTAAAACATTTCTTTCCATTCGCTTTATTTTCAAAACATTGCAATTCTG GGAACTTGATGGGATGAAAACTTTTTTCCTCTTCTTTGATATTGAAAATCCTGGGATAATATCTAAAAGA CTAGTTCTAATTGGGGTGCCCTGAGACATGTTTAGTAACCAGTTGTGAATTCCAGAACTAAAGCACATAA CAGTGTTTAAAAAAACACTTGGTTAGCAAAGGTGTCTGGAAAACATTAGCAAGGCATAGAATCTGTTCAC AGCTGCAGGCCCCTTGGTCAGGTCATGTGACAGGAGCTGGCCTTTGTTTCCCAAGCAGTGACCTCTACTG AGCTGCATGTGACCTTTTAAAAGTGGCCAGCAAATGAACAGGGGGAGGAGGGCCATAAGAATGAGTTGTT TTGGATTAGTGGGGAGCCGATGGGACCGCAAGTCAATTGTGAAGTTAACGGAGAAGAGACGAGCAGTCTC AGCCCTGGAGTAAATACAGCACTCAGAGTGAACTCCAGCGACACCAGCCCTCAGCAGCACCCACTGCCAC TGATTAGCCATGGCCCTTGTCCTAAAACAGGGTTCTTTAATGTTAGCCCAACTTCAGCTTCTCTCCCTGC CCTGGAATCACGTAGAACTTTTTTAAAAAATGCATCAGAAAAAAAGAAGGGCTGCGCTGTGTCACCTGAG ATCTGTGCTGTCGAGGCTTGTGGAAGTGTTCATTGCATTTGGGCATTTCGCATTCTGTTGTGACCACAGG TGGTTCATCAGAGTGTCGCACAGAACTCCACTCAAAAGGTGCTTTCCTTCACCACCACGACCCTGGACGA CATCCTGAAATCCTTCTCTGACGTCAGTGTCATCCGCGTGGCCAGCGGCTACTTACTCATGGTAACGCTC GATGCCATGCTCCTGGGGGCTGGAGTTTGGTTTGGTTGTTTTAGTCTTTACTTTTCCATGACTGCTCCTG CTTCTTAACTGCTCTTAACATCGATGTGCATCCAGGACAGAGAGAGCGTGGCTTCACAGTGGTTTAAAAG TGGTCGTGTAAAGCATTTTTCCCATTTGCCGTTTGCCTACCTTTGACTCCTGTCATTTTATGTGACGCCC TTGATGTAAAGTTTTGTTGTTGTTGGATAAGTTCTGCCTTTTGATTTGGGGTGATGGGTGGAGGGAAACA TTAGAATCACAACACATTCTAATGTTCGGCTTTTGTTCTGTGCCCCCATTGTTCTGCTTGCAGCTCGCCT ATGCCTGTCTAACCATGCTGCGCTGGGACTGCTCCAAGTCCCAGGGTGCCGTGGGGCTGGCTGGCGTCCT GCTGGTTGCACTGTCAGTGGCTGCAGGACTGGGCCTGTGCTCATTGATCGGAATTTCCTTTAACGCTGCA ACAACTCAGGTACTAAAGGAGCCATTTATCTGCTGTCCGTTGACAAATGCCACCCGGCCCCCAGGCTTGG CCCAGCCAGCCTCCTGTGTGCTGTGTGTCCTTCTCACCGGAAGGGTCTTGCAGCCTTTTCCACTAGGATG CTACTGGTTTCAGGGGAATGCTGTCTCTTGATGCTGTCCGCCCTCAGGGAAGTGGGTAGGAAGTCTGTTG GGCTTATTGGTTAGTAGAGACACTTGGCTGATAGGAATGTATGTCATTGACCAGGGTTGTGGCTCTTCAG CTCTGGTGGGCATTTGCATGGCTTGCAGGGCTTGTGAAAGCTCCGATTGCCAGGCCCCACCCCCAGAGTT TCTCAGTAAGTCTGGGGCCGGGGCTGAGAATGTGCACTTCAGGGCAATTCCCAGTGATGCTGGTCCATGG GCCACACTCTGCCAATCATTGCTTAAATGAGTTGGATTCCTTCTCATTTACTAGCTTAAAAAATGATAGT ACACTGACTTTCGAAGTAGAAACGTGCAGGATCTCCTGTGAGCTGAAATGGCTAGGCTTTGGGACGTCAA GTGAATTCTTCACCATGAGGTTACGGAAGCCCTGCTTCAGGAGCTGTTAGGTGCTGGTGGCAGAGTCCTA ACTAGCTTTAGAATCATCTGAATTGCATCTCGCATGTCTAATGCCACCATCCTCTGTTTTTGCTGTAGGT TTTGCCATTTCTCGCTCTTGGTGTTGGTGTGGATGATGTTTTTCTTCTGGCCCACGCCTTCAGTGAAACA GGACAGAATAAAAGAATCCCTTTTGAGGTAATGCAAAAACAAAAGAAGAGAGCTTTGGGGACATCACAGC TTCCTCTGTTCCTAAGTATTTGTCCTTTAATTTTCCTCAGTCTGACCCAGTAAAGATTTCAGTCCCATGT CAGATGATGTGTCACTGGCTGCCAGTCAATGAAATAAGCTGGAAGACTCTCAGGACATGTATTTGCTATG AGAAGTCCCAAGAGCTGCATCTCGGGTGCCTTTAGGAATACGGGTGTTTGTTTTAATGTGACACTTTATC CCTAACTGCCATACATTCCCAGAGCCTGCATTTGCTTCTCTGGAGATGTCTGTCACTTAGCCATCACCTC CCTCCACTCCCTTTTAAAATTATACTTAAGCGTTAAGTCATTATCTTGCAGCTTTCTTCTCTGGATGGTA ATAACCATGAAGAATTGATGACTCTGTAGATGGTACTGAATAATGCTGGTGTTAGGGGGTAAGGCAGGTG GCTCTGTTTCCCTAATGCCAGCATGATAAGCTGTAATAACAGTTGTGTTATTCTGCCACGTATCTGCTCA CACAGTCTGTGCTCCAAGGGGACCATGTCCAGTGCAGCTCTCAGCGCTGTGTTTTTTTATTCCCAGGACA GGACCGGGGAGTGCCTGAAGCGCACAGGAGCCAGCGTGGCCCTCACGTCCATCAGCAATGTCACAGCCTT CTTCATGGCCGCGTTAATCCCAATTCCCGCTCTGCGGGCGTTCTCCCTCCAGGTGAGCTTCTGGTGATGA AGGCTGTGGTGATCCTGAACGGGGCACTGACTTCCAGCATCCCATGTCTGCGGTCTCTGCTAAGGCACTT CAGTTACTTATGAAGTGAAATAGAAATGCCTGTGTTTGAGGCTCTGTTTAACTGGGTGGATGCTGCTTTA AGCTTATAACCCTGACACTCCCTCTAAAAAACTAAGCCCTTCTGGAGTTTTTCCTTCCTTTCTAGCCCTA TGAAGCCCAGACGTCTGTTGCCTTATAGAGTGGCCATGTCCTTTATGCATGGCTTTCGGGGCTACTCCAT GTTGCCCTCTGGGGTCACCAGCGCTGCAGCCAGCTTCTGGGCCATCCCCTGCTTCCAAACACCACTCCCA GTACCTGCACTTACCCCCTCTCCCGCTGCCCACTTGATCCCAAACAGGCTACCTTTTCTTTCGCTTTTGC CAAAGCACCCCCAACCCAAGACAGTATTAAGCTGAGGTCGCATGTCAGACGGCACTGCAGGACCGCGAAC TGGCGAGGCTCTGTGGAGAATTTCCTGCAGGGTCCGCCTCGGTGGGCCCTTTCTTTCCACCTCCCTTTCC TAAGTTGGCCGCCACAATCTTTCCTGTCCCCTCTTCTCTTTCCTTTTGGTCCCCTGCTCCCCTCTCAGGC TGCCCAAGCAGACTCATGATCCCTCTCACCTTCCCATGCAGAGCACGTGGGCCCCTCGTGACTTGTCCTC TCCTTCCAGACCAGGCCCCGTCACCCCCAGAGGCCGTCAGGGTATTTTCTAATCCAGACTCAGCTTCTGT GAATTGTAAGCATGGACAGTTCCCTGGGATGGGGATAGAGCTGTAGTCCGTTCTGCGCCTGGAGTAAATT ACTGACGTTGCCCTTGAGCTACCTGAAATTCATAGGAATCCTAAAATTAGTTACTGCAGCCAGTAAAGCA GAGACTTCACCAGTTTGTGCCATGGTCTTCCTGAGCGCAAAGTGGCCTGGAGTTTTGATATCTCAAGATG TTGTGGGGGTTTTGTGAATTAATTTCAAATTTCAAAACCTCAATTGTTTCCCCTTTCTTTCTCTGTGATG ATATGATGTCTAATTCTCAAGCTGGCCAGGTTGTTAAAGGAAATGACTTCTGTGTCACTTTTTCACTTGT TGTTAGGATGCCCGGCACACTCACACAGCTTTACTCTACTCACCAAGAGTTCCTGCAGATGCGAGCAGGA AGAGAAATTGACCAGTCTTGCATCTGGTTTCTGTTTATATTTTGTCAATATGTTTAGCTCTTTCCTAGTC TTTCCATTTGTCATGTAAGAGGAACCAATCAATCACGTATTTGAATGTCATTTCGCTAGTAACCAAGAGG CCTGGGCAACTACTGATCCTACTGGGTTTGGGAATGGAGGCATCTTTAGTATTTAGTGTGAGGCACAGCT GGAGAAAAGATTCTATGCCAATTACCGTAACCGCCAGCCCCAAAAGAAACATAAAAAGAAAAGAAAACAG GGTTTATTTATATTATAAATTTATATAGAAGTAAAAATAGTGAATCAATGAATAACGTTCAGATCTGATG CTCGAACCAAAGCACAGGACAAGGAAACTCTCTCTGATTGCTCAGTGGCATGAAAGGTGAACCAGACTCG CAGTGCAGCTGAAGTTGTAGAATGCCTTTGTGCGCAGGTGTGTGTCTGCTCAGCACCCTGTGGTACCCCA GTCTCATTTCACGTGCAGCCGGTGCTGGTATTGAGAAACTGTTCTAGAGTCTTTTAGTCATGGGACCCTG TCTGCCCATTCTCTCTCCTCTCCCCTTCTTTTCTGCTTGCCTTTTTGCTCACTGTCTTTCTGTATCTGCT CATACTCCTTCTTTTCTTCTTTTCTCTCTCATTCTCTCCTCTCCTCTCTTAGTACATACTGATGGCTCAT CGAGGCCGACTCTCCTTTAATGATACCCTGTGGTGTGGTGGTCTGAAAAGCTACATGAGGTTTCCTTACG AGGAGTAGCCTTGTAGAAAATCCAGTGCGCTAAATTCTCCCAAGGTAAGCACCTTACAGAGACAAAAATG AGTACTGTTGGTTTTTGTGTTTCTGTTTCAAAGCACCACAGTATCACTGTAGAAAATTGCAACTATAGCT TCCAAGAGTCCTCATCTTACTGAAGAATACCTCCTCATGACACTGGTTAATTCTCTGTCAAAAGAAAAAA GGAGTGCTTCGCACGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGACGGGTGGATCACGA GGTCAGGAGATCGAGACCATCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAATTTGCC GGGCGCGGTGGCTCACGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGG GAGGCGGAGGTTGCGGTGAGCTGAGATCGTGCTATTGCACTCCAGCCTGGGTGACAGAACAAGACTCTGT CTCAAAAAAAAAAAAAAAAAAAATAGGATAGAAAATGCAAAGAAAAGAGAGAGTGTGCAATGATTTTTGC AGTGGCCATCAGAAAATTTTCCCTGGTTCTCTTTTAAATGTATTGACCCTCAAAATTGGCCATTATGTAG CTTCTCTTTCCATTGATGAACAGTATCAGGTTTGACTCTGGGTGTTCAGTTGTGTTTATATTTGCAAGAT GCTACAGATTAAACATCAAAAGGGAGTGACCCAAGGCGGTTCTGTCCAATAGTAAACCTGCGTTACCTTC AGAATTTTCCATATAAAACTCCTCCAATTTTGTAGCCTGACCAAATAATTAGATATTTTTTTCCACAAGG AAACTGTCTTAAACCTCATCAGCCTTTATCCATCTGCCTAAATGCCATCTCTACACCAGAAATCACTGGC ATCAGCTGTAATTCTTTGTAATTAACTAGGGCTTGCTGGTAGCCCAGTAGTGTTTATTCTTCAATGAAAA CTCACAGAACAGAACCCCTTGTTGTTCTGTCTGGTCTAGGAGGGTTCAAGTGGAACCTCCTCTGCATGTG TCCCAGCCTTAGCTGCTTTGAGGGGATGGGGCATTTCCTATGAGTACAATAACTAGAATTGATTCACAGT TGCAGTATCATCCCCATCATCTTCTCTGGTTTACTTACACTCTCTTGCCTTTGCGACAACCCTTCTTGCT TTCTGAGCAGCCCTTGCTGGTTGTTTTACTATTTTGGTGTACACCTGGGGACCTGGCACTGAGAAAATAC TCCGCCATACATGTAGTAGGTTATGAGAAAGTCAGTAAGATGGGACGCTGCTTGGGGTTCTTCCCTCATC CCTTCATTTCCGTCATGGACACGGAGCAAGGTGCCCAGCAGGCTTCTCTGACCGATGAGGCCGGCTGGTG CCCATGCCTGTGCCCGTGGGGCTCCCTGTGTCACGAACCTCTGCTCTCCTCATCCTCATGAACACCTGTC CAAATTGGGATGCCCAGGGTCTCTTCTCTACATTCCACTCCTCCATTCTAAACATGACTGATTTTAAAAG CTAAAAGGATTCGGCCCCCAGGATGACATCTGGAAAATCTCCGTTAGAATCCTACCTGTTCTTCCTGCCA TCCCCTGCTGTCTCACGGTCAGGTGTCCTAACCCCGTCCACAGACGTCCTCTCAGTAAGGGACCAGATCT CACAAAACTCCCGGTTCTCAGCTGAGCTAGGGGCTTGGCATCAAGTCTTTGTTTGATCTGATTTACTGGA TAACCTCAGGCAGGTGACTTGACCGCACTTCGGGGACTTTATCAGGTAATACTGTCAAGAGCAGTGAGAA CCTCCTGTTTGCTATGAATCAGGTATGAACGATCTGATCTTCATAGCTTCTCCTTTCTCTTCCCCAAAGT GAATTTCAAACCCCAGCAGTACTGAGGTGCTTGAGCCAGGTGTCTCCTCTTGCACACTCTGTGTTTTTTT CACAGGGAGCACCTGCCATTCCCCTGCTCCTGACTGATCTCTTTTGCTTTTCTTTTTTGAGACGGAGTCT CACTCTTGTTGCCCAGGCTGGAGTGCAATGGTGCGATCTCGGCTCACCACAACTTCTGCCTCCTGGGTTC AAGCAGTTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCATGCGCCACCACGCCTGGCTAACT TTGTGTTTTTAGTAGAGATGGGTTTCTCCATGTTGGTCAGGCTGGTCTCGAACTCCAACCTCAGGTGATC TGCCCGCCTCGGCCTCCCACAGTGCTGGGATTACAGGCATGAGCCACTGTGCCCGGCCCTCTTTTTCATC TTATAAACCCTGCTGAAGCCTCTCCCGGGAAGCCTGCCTTGACTGACCACCCCTCCACCCCACTGAGCTG CTCTGCAGCCTGACACCTGCCTTCATGACGCCATCCATCATTCGAGATTGTCATTTGTGTATAGGTCTGG CTCTGTGAGAATTGAGAGTAGGATTTTGTCTTATTTATCTTTGTGTCTCCAGCACCCAGCACAGTACTAG ACTTTTCTTTTTAAAAGATCTCTCTCTTTCTCAGGTAAATTCTCTTGTCACAGTGGTGATGAGCTTATTT GTGTAGGTCTATCAGACAGGTCTTAAATACATTAGAGTGGTAAGCTAACATGCTTCATATTTTTCAGTTG ATGAAGGATTTTCAAGATAGACCAAGAAGAAAGAGGTTAGGTAGTTTTTAGAAGAACGCTCTTGAGAGGG AATTAATTATTGGAAGACATCTCTCCGGAACTCAGGCTTGCTGGTTCACCTTCAGCATAAACTCACAATT CCCATCCAAAGCCCTTTGTGGAAGTTCTCCCTGGATTGTGTTAGGTGGCAGTTATAGCCAGGTTTTCTTT CCTCACCCTAGGACGTTTATCAGTTTGAGATTTGTGAACTAAGCAGTTCTTTGAGAAGCCTCGTTTTTTA TTTTCTTTCTTTCTTTCTTTCTTTTTTTTTTTTGAGACAGACTCTCACTCTGTCACCCAGGCTGGAGTGC AGTGGTGCAATCTTGGCTCACTGCAACCTCCATCTCCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTCCC AAGTAGCTGGGACTACAGGCATGTGCCACCACACTCAACTAATTTTTTGTGTGTTTTTAGTAGAGACGGG GTTTCACCGTGTTAGCCAGGATAGTCTTGATCAGGAGATCCCTGACCCCGTGATCCACCCACCTCAGCCT CGCAAAGTGCTGGGATTATAGGCGTGAGCCACCGCGCCTGGCCTCGTTTTTTATTTTCAAAGCCATGTCT GGCAATTTCCTGGCTCCTCAGCATTGCCAGTGCTTTTCTCTGTGGTGCCCCTTCTGCCGTGCCCTTCCGA GCTGGGTCGACTTCCACCGGCTTCTGTTGGCTTCCCCTATTAACAGCCCAATTTTGTAATTTTTACTAGG TCAGCAGAAGATTTGCCAACGCACTGCAGAATTTAGCCCTGTGTTTATTCTAGGTTATGGAGTGACTTTT GAATCTGTACTTATTTATTCTGCGTACTATAATCACACACAGGAATTTCTTTCTGCTTAACTCTCCTTGA CCTTTTATGTTTCTTGCTCTCACACCCCACAGGCTACTCCAGAGGCAATTTGGAATGTGCCTATTAAAAC CTCAGGGGACACGTGTGAAATTGTATTTCACGTTTTAAAGGGGGACATTTTGATATACTCGATCCACTTT ATATAAAAATGTTTAACTGTAAAATCAGGGTCGCGTGACCTCTTGGAAGCATTCTGGAAGGGAACTGCTT CTGTTTGTTTTAAATTCTATCTCGAGTGTGCTCTCTGTTCTGCCTTTGTGGATTTGGTTTGGTTAGGTTA CTAGCAACACGTTAGTAGTTTAGTTCCCAGGTTTGTGCCTTATCGGTTTATGGAATTATTAGAGATAGAA AGGCCCAGAAACAGTCAAGACTATTCCTATCAAATAGGCTCTTGATGATGTAGCAAAAGAAACTCTTAAC ATCTGTCACGGTTTCAAATGCTTCAAGAGGAAAGGGAAAGAAAAATATTGTTTAAAAGCATCTTTATTTT CGAAGCAGTCCTCTGATTGGGCGGAGGCATGTTGGTGACCTCTGAATTTTTTTTCTGCTCCCAGGCAGCG GTAGTAGTGGTGTTCAATTTTGCCATGGTTCTGCTCATTTTTCCTGCAATTCTCAGCATGGATTTATATC GACGCGAGGACAGGAGACTGGATATTTTCTGCTGTTTTACAAGGTACATTTTCAGACTGCTGTGGCCTTT TGATTGGGTGCAGAATGGTGCTGTGAGAGAACTCTTTCAGCCTGTGGACTTATAAAGGAATGTGGGTAAC GGGGTTTGTGCTGGTGTGGAGAACGTAGGGGAGAGATTGGACAGAGGCTGCTTCCCTAGGGGGACATCAG AGTCCCTGGGCTTCCTTCTCCCCTGCCGCAGCTGAACAGTCTCACAGCCCTCAAGATGCTGGTTCCGATG ACCCCTTTTTCCATCATGAACTGATGTTGCCGATTGTAGGAATGTTTCATATCTCTGCATTAGAGCAGAA CAAGATTGAAAAACACCCATCTAGAAAATATATAGTCCTTTGATGGTGGTTTGGTTTTGTTTGGAATTGT GCTTTGAAGGATTCATCATCATGGAACTTGCTTTTGAAAGCCAAATTTAGGATCAGTCCTCCATGTGGCC TCCTCAGACTGACTTTTATCTAGTTCACCAGGCGATGAACCAGGTGATGTTATCAACCAGGCGATGTTTC TGGAATTCAGCAATGTGATGTTTCTCTCCTAAGTCAGAGCTGTGTAAAATGGGTATTCTCCGTACACAGT GAAAAATGGCAGAATGAAAGCACCATTTCCCTGTTTCAGCATAACATTGCAACATGTTTCCCCTCCTTTC AGCCCCTGCGTCAGCAGAGTGATTCAGGTTGAACCTCAGGCCTACACCGACACACACGACAATACCCGCT ACAGCCCCCCACCTCCCTACAGCAGCCACAGCTTTGCCCATGAAACGCAGATTACCATGCAGTCCACTGT CCAGCTCCGCACGGAGTACGACCCCCACACGCACGTGTACTACACCACCGCTGAGCCGCGCTCCGAGATC TCTGTGCAGCCCGTCACCGTGACACAGGACACCCTCAGCTGCCAGAGCCCAGAGAGCACCAGCTCCACAA GGGACCTGCTCTCCCAGTTCTCCGACTCCAGCCTCCACTGCCTCGAGCCCCCCTGTACGAAGTGGACACT CTCATCTTTTGCTGAGAAGCACTATGCTCCTTTCCTCTTGAAACCAAAAGCCAAGGTAATCTGCCACAAC TTAAGGCTCTTCCTGTCTTCAAAAAAATAACAGAACCTTTGGAGTTCATCAGATTGCTTCTACTTTTCTT CTTTTTCCTTAAAAAAAAAAAAATTTCGTTTAAGTATGATACATTTCAGTCCTCCAAAAGTCAATGCTTT TAGAGCATAGGGCCATTTTAATGAGGTCATCTTCCATGGGAGTGAACCTCTATGCAGCAAGTCTTTTTAT GAATGAGGTTGTTTAAAAATGTGATTATTGCCACTTGCGGTGGCTCATGCCTGTTAACCCAGCGCTTTGG GAGGCTGAGGTAGGAGGATTGTTTGAGCCAGGAGTTCGAGAACAGCCTAGGCAACAAAGGCCAACCCTGT CTCTACAAAATATTTTAAAAATTAGCCAGGGACAGGTGTGGTGGCTCACGCCTGTAATCCCAGCACTCTG GGAGGCCAAGGCCAGCGGATTGCTTGAACCCAGGAGTTCGAGAACAGCCCAGGCAACATGATGAAACTCC ATCTCTACAAAAAATTGCCTGGGCATGGTGATGTGCCTATAGTCCCAGCTGCTTAGGAGGCTGAGGTGGG AGGGTCACTGAGCCCAGGGAGTCGAGGCTACAGTGAGCCGTGATGGTGCCACTTCATTCAAGCCTGGGTG ACAGAGTAAGACCCTGTCTCAAAAGAGAGGGGGAAAAAAGGCATGGTGCTGTGTACCTGTAGTCCTAGCT ACTTGGGCAGCTGAGACAGGAGGATCATTTGAGCCCAGGAGTTGGAGGCAACAGTGAGCCCTGATCATGC CACTGCACTCCATCCTGGGAGACAGAGTGAGATCCCAACTCAGATACATAACAAAACAAGGCTGGGCATG GTGGCTCACGCCTGTAATCCCAGCACTTGGGGAGGCCGAGGTGGGTGGATCACCTGAGGTCAGGAGTTCA AGACCAGCCTGGCCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAAAAAATAGCCAGGCGTGGT GGTGCACACCTGTAATCCCAGCTACTTGGGAGGCTGAGGCACGAGAATTGCTTGAACCTGGGAGGTGGAG GTTACAGTGAGCCGAGATGGCACCACTGCACTCCAGCCTTGGCAACACAAGACTGTCTCAAAAAATTATA TATAAAACAAAACAAAATAAAAATGCGATTACTATGATTTTATCCTTTTTCCTATGGGAGAACAACCCCT ACAAGATAAATCAGTTTAAGTGTGGTGGTGAAAACAAGGTATTAACTAGACAGCTTCTCTTTGTCCAGGA AGAGTCAGTGGTGCTCCCTGGGGTCTGACCTTGTGCCTCTTCTGTTCCAGGTAGTGGTGATCTTCCTTTT TCTGGGCTTGCTGGGGGTCAGCCTTTATGGCACCACCCGAGTGAGAGACGGGCTGGACCTTACGGACATT GTACCTCGGGAAACCAGAGAATATGACTTTATTGCTGCACAATTCAAATACTTTTCTTTCTACAACATGT ATATAGTCACCCAGAAAGCAGACTACCCGAATATCCAGCACTTACTTTACGACCTACACAGGAGTTTCAG TAACGTGAAGTATGTCATGTTGGAAGAAAACAAACAGCTTCCCAAAATGTGGCTGCACTACTTCAGAGAC TGGCTTCAGGGTAAGACGGCGTGGGAGGCTCTCGTCCTTTCGGTCTTTTGCGTGTTCAGCTTCAACAGGT TCCTTTGTCATGATTATGAGAGCGTTAGATTAGAATGTAACACTGACGTGTTTCATGGACTTTTAAGAGT TGCTCAAGATTCTTACATGAACTGTTTCTGCAGCAGCCTCCCAGATCTGGCTTTTACCTATAAAATGATG CAGATAATTCAGATGAGCTTCTGTGAGAATGTACAAGTGCACGTCAGGAAAAGGGGAGCATGTTGTAACA GGTGGAGCCGAGGCTTCTGGTGCTCTTTCCTCTTGGATAGACGGTGGCTAGTTTGGTGACCACATAAAAT CAAAGTGCGGCTGGGATTTCCAGACTGATTGCCAAATTATAGCTTACTGCACCAGGAGATGCTAGATAAG CAGTGGACATAGTCTTACACTCCATATTTTGACCATCTCTTTAAAAATTATCTATTTCTAATTGACTTTG TTTTTAGAGCAGTTTTAGGTTCCCAGGAAAATTGAGCAGAAGGTGCTGAGATGGCCCATATCCCCCTTCC TCACCCACACACAGCCCCCTCGACTGTAAACATCCCGCACCAGAGGGATGCATTTGTTACAGCTGATGAA CCTGCACATTATTACCCAGGCTCCATAGTTTACGGTTGGGTTCATTTTGACCATTTTTTGATTTGGTACT TGAAGTAAAGTTATAAATGCTTAGTAACATTTCACATTATTTTATAAATAATTAAATTCTGTTTTAAAAT GCCTTTCTTGGTGGGGCACAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGATGCCAAGGCGGGCAGAT CACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCTACTAGTGAAACCAGCTCTCTACTAAAAATACAAAA ATTAGCTGGGCGTGCTGGTGGGTGCCTGTAATTCCAGCTACTCAGGAAACTGAGGCAGGAGAATCGCTTG AACCTGGGAGGTGGAGGTTGCGGTGAGCCTAGATTGTGCCATTGCATTCCAGCCTGGGCGACAAGAGCGA GACTCCATCTCCAAAAATAATAAATAAATAACAGTGCCTTTATTGGCTTCTTCACTCTTAGAAATGTTTC TAGGAAATATTCATCAGCTGGAGGGGAAAAAAAAGTCTAAATTTTCTCCTGACCGACTGCACGTAAATGT ATGCAGTGATTCCAGGAACATCTGTTCATTTATTCTGCATTGACACATGCAAAGCCAAGTAGAGAATCAG GATAATTATCCACCCAATTCAAGCAAAACACTTTTACTGGAGTACCAAATCATTATGGCCCCCAACATTT TTTGGCTTGGATTATCCAAATGATTGTCTTAATTTCCCACTTAATTAGGCTTGTTTAAACACAGATGTAA GTGCCTTTTTTGGTCTGAAGTCAATACACTTGTATGTAAAGACTCAGCAGCCAGTTTCCCTGAGAGTTTG CAGGAAATGGTCAACAACTTGAGGTTGGTAGAGGATGGTTCCATACAGCTTCTGGCCTTGACTTGTGTTT ACCAGAACTTTGTGTCTACATGTACACCCAATTTGACTTTCCTTTTGGAGGAAGGTACAGAGAACATGCC ATGATTATTATTTATTAACACCCTCCTGAGACGAACGTGAATTTGTTCCAAGTTTTATTTTTCACATTTA GTTTAGAAAGCAATGGTTTTTGGGATAATGAGTTAAAAGAGAGACAGTGGAGAGAGTCCCTGCTTTCATT TTCCCCCCATTGACCAAAGACATATAAATAACTTGCCACAAATGACAAAGAGATCTGCTGTGCCCTGCCA GTCTGTGAGCAGAGAAGGGTTATTGTAGAGTGTATTTCAGTGTCTTTGGCCATTGCTCTGGAGGCTCAAT GTGGCATGTTAGGCAGGGATTGGGAAGGGGGTAAAGGGGGATTGTCTCGAGGCAGTGCAAAGGGTTAACC TTTTTATAGAGCATTGTAGATCATCTCTATACGTTTCTTCCTTTATAGATGTAAATCAGCTGGAGTTGAG TTTTTTTTTTTAAGGTGCATTTGAATCATGTTTTGATTGCTGTGTGAACAGCATACACCTAGACCAAGTG AGATCCATTGGTGCTAAGCAATCAGGGTCCCAGGCAGCCCTGGGACTCCATGACTGACTCTTACAGGGTC CGCTAGAGCACTCAACACAGAATGACCAGACACTGGAGCCCTTTGCTGCCTACACGTTTTTCAGGCCTGT TGAATGGTTGATGTGGTGTTTGAACATTTTCTACAAGGAAACAATTATCCTTGAGTCAGCTTTCCTTGCT GACATTTTTGTGTGGCTTTTAAATGGTGGGAGCCTCATTGGTTTTTAATGGAATTCCCATTAAAACTATG TCATCTCATTGGTCTTTATCGACATTACAATAGTTTGTCTTTGATTTTTTTTACTCCTAAAACTATATAA TGGTTAATTTCAAAACTATCCCACATGTCACATCTTAAAACATACATGCAAATAAGGCAGAGTCAGATAA AAACCATGCCTCGAGTCATGTACAAATGTGTTCATTTTTATTTCACACTGGATTATGCAAACAAAATTTT GATTAACATTTTACTTCTAGGGTCCCATAGCTGAAGGAAAATGGGCAATTGGGGTTATTCCTTTGGCCTA GAACTTTACATTAGAAAATAATTATTGACACAAAATATTCATAAGAGGAGAACTTCTAGCTAAGATATTA AGGTTTGCTGTAAAATAAGTAAAAAGTCACAATTTTCTAGAGTGTGCATGCATTGGAATATGAAGCACTG GCTAAAGGGCAGTGGAAACCCAACCTTATCCCTTGTTTTGTATCCAGGGTCGTACCTTGTACATGTGCTT AGGCCAGCCCCTTGTTACTTGAGCTTTTTGGTGATTAGTCAGAAAATACTGTAGTAATGGGGAAAGAACT TAACTGTTCCAGAAAGTCGATGACTGTTTCGTATTCATCTTTGAACCCCCAGTAGAGTGAATGGCACCTA AGTGACCAGCAGTGTGGATTCTGAGTTGAATCGAGTTTCCAGCAAGGCTGACCTCCCCAGATAGGATCTT TCTTCCTTTGTTTCACCCTCGGGTGTCCCAGAAGTCTTTGTGTGTGAATATCATAAAACCGCCCCCAGAT TTTGGGGACCCCGTTTGCCACCAGATGTTATTGATGCTGGAGTTGAACCTGCTTGTCTTACTCCTGCCTT TGACACATCCTTGGGTACCACGGTGTGTCCCCGCACTGTAGGCCAGTGAGTGGCTCCAGCTGCCTCTGGT GACTTGCTGCCTGGGTTTGAGCTCCATCCAACACTCACCTGCTGGGTGGCCCCCTCCAGTCTCCCCTTTC CAAGACTCAGTTCCTCCATCTGTGAAGCCGGAGTGATTAACTCTAACGGGGCTGTCCCTTGGTTGCCGTG GGATGCCCAGCGCCACCCCACACTCACCAAGTGTGAGCCTCTCTTCAGGATTAGCTGGTTAAGGGAGAGG GGCTTAAAGCCCAGGACACGTCATGACATCATGAAAATTGTTACAGCGAGGAAAACAGACGAGGCCTCCC TTTTTGAGGGGAAAGGAGGCGCAGTAATTTTTCTTCTGCTGTTTATTGTTTTTCAAAAACAGAAAGAAAG GGCTTTCAGTAATAAAATAACATCTGCTCAGTACCCTGTGTGTGCATGCCTCCCTATGAAAACCCGTCTG TCTGAGAGGTGCACGGCCCACCCGGTGGTCTCCTGTCCCGTCTCCCCTCCACGCTCACCCTGACACAGAC TCCTTTCACCACCGAGCCCACTGTCATCCCCAAATTGTTCCTCTAGCCAGTAGTGTCAGAAGGAGGGTTT CGCTTCTTAGAGAGACAGAAGGGGGCCTGTGCTCCCCCTCCCTCCCCACACTTCAGACCCCAAGAGCTTA ACCATTCTGAGCACTAACGCAACCAGATTTTTTTTGAAGCCTTTGAAATCATCCAAGGCATGTCCCGAAA TGAAATAAACGCTTCTCCCTTCTTACTAGCCGTGTCCAACCCATACATGTACAGCTTGTTCAAAAGCTGT GGTTTCCTGAGCTGCTGGGGCTTGGGAGCTCTACTTGGGAGGTGGCTGGGAGGGGCAAGGGTGGGTGGGG GGAGGGGGGTGTCCCGGAGAGCGTGCGCACCAGCCAGCGCTCAGACCCTAAGGCCGGGTCACCGGGGCCC TGTTTTCTCTTCCAACATGCTTATCTCTTTACAGCTGCAGCCAAACCGTCAGGTCTGTAATGATGGTTTT GATTACTGAGGCCAAGCGCAGCTGTGTGTGGTGTGCTGGCGGGCTCGCCCATCCCCCAGGCCCAGAAAGC TCTTTCCTCCCCCTCCCCGGCTTGTGGTTTGTCATCTGTTCTCACAGAGCCTCCTTGTATTGGCCTGTGG CTTCCTGTTCTCAATCGGATCCAAATTTACCCTGTGAGGTATTTCCCTGCGTGCACACGAGCGCCTTCCC TTCCTTCTCCTCCACCCCCTCTCCTGAGGAAGGGTGGCAGAGAGGAAGAGAGCAGTCGAGAGTGAATAGG TGTTGGCTGTGATCTTTACACAACCTGGCAGCGGATCCCACAGCTTGTGTTAGCTCCACAAGTCGAACAG ATGGAACAAATTGACAGAATCGTGTTCGCTCACCCTGGGCTCCAGAAGCAGCTGAGCTGCTGTTTGAAGT TGGGGGAGTTTGAATGTGCTTTTTCCCCTCTGTGTGGAATTTCTGGTTGTATTGAAGAACTCATGACTTA GCACCCCGAGTGGCACGAAACGGTTAATGACCCTGGTGCGTGTCTTTCCGTCGCACTCTTGCCTTCTTTT GTAATTGTCATGGGGCGAAAGGAGGAGAGTGGTTTTTCTTAAGATAAAATATGAGTATTTGTTTCATAGA AACAGATAATCTCCTTCCCCCCTTTTGAGCAGTGGCTGGCAGCAGCTGCAGTTCATTCATGAAAGATCCA GTGCTTTCAGTCAAAGTGGATGTGGGACACAGAGGGTGTGTTTCTGATGGACGTCTAAGAGCCCCCTGCC CTGCTCAGTCTCCTCAGCCCACCCCGCTAGGACCAGGGTCCTTCTGGCTGCGAGTTATAATGTGTTACAA TCATTTGCCATTTCTAGGACTTCAGGATGCATTTGACAGTGACTGGGAAACCGGGAAAATCATGCCAAAC AATTACAAGAATGGATCAGACGATGGAGTCCTTGCCTACAAACTCCTGGTGCAAACCGGCAGCCGCGATA AGCCCATCGACATCAGCCAGGTACTCCAGCTGCTGGGCACTGAGGGCGCTTCCAGGGCTGCGGGGCCGCT GCCCTGGTGGAGGCTGCTTGACAGCGTGTGACCCCACCCTGTGCTCTCTGGAGACCTAAGGCACTGGGAG CTGGTAGAAAGAATATTGGGTGACTCTAATTCACCTCCTCCCACCAGCTAATTGTGTGACCTCAGGCCAG CCAGTGCACCTCACTTTCCTCATCTGTCAAATGGGACAGGCGTGTTCCTACCACCAGAACAATTGTCAGA ATAAAGTGCAGCCAAGAGAGTGCAGGCTCTTTCCAATGTTAGAAATGCAGCGGCGTGTGATTCTTTCAGT TCTAGGACTCGGTACCTTGTTGGTCTTGATGGTATTCAAGCTTGGAAAGATGGATTTCTTGGGTAGCAGT CATTTGGATGAGCAGAATTTGGGGTAGGTGGGTGGGTTAGGAGATTGGAGAGGTGACAGAAGGATGGGAA GATTTGTTACATTTGAGATCTTTGGGTGGCCCTGGCCCCAGGAGTAGACAGATCGCTCTGTGATGAGTGA AGCAAACGGAAATGTGCACCCTTGGAATCAGAGTGGCTGCGCCATTCTGCTCACTCCTGCAGTAATAACC GTTTCTGTTTGGGAATCATATTCTCCACTTGTGTTTGCATCTTCTTGCTGCCATTTGGATTCCAGCATAC CCCTTTTGGTTCTGCAGGTGTGTTCAGGAGTGTGTTTTGGACTCCTCCAATTGCACGGGGCCCGGGCTAC CTCAGCTTCCTCGGAGCCTCTTCCCTTGGCTCTTTGTAGCTTGCTTGCTTCACCTTCAGGCAGAAAACCG TCATGCTAATGATCTTCTCAGCAGCTATGTTTATTGTCTCCCCTTTTTTGCTGGCATTCAAGGTGACAGA TTTACAAAGTACATTGTTCAGAGTTGTTATGGAGTGTGAAACTCTGAGCTCACAGCAGCAGGCAGCAGAC CATCACGTTTCCCAAGGATGCAGGCAGAGGAGTCTGCCTCAGAGACACCAGGAAAGTGCCCAGGCAGCAG GGCTGGGCGAGGGACCAGGGATACTGTGGGACAAATGGGATTGGGCCAGACCCCCAGATACCATTTCCTC CTCCCGGGAGGGAGAAAGGCGTGCTGCATGCACAGAGGCCACGGGCTGCGCTGTTTGATTCCAGGGATGT GTTGAGGACATGCAGTTGTTACATATCCTGTGGATTAATTGAATCCAGATCCCCGAAATCCAGTTCTCTC ACTCTCTCCCTGCTCCTTCTTCCTTCACTCCTTCTCTAGGAGCCGCTGTCACTGGTGTTTTTCATTTTGT TTAAAAAAGACCCAAAGCGAGGAATGAGGCCTGAATCTAAAATAAACAGGAAACGGAATTTTTCTATGTA TATAAAACGTACAAACACATACTGAGTCCCACAGAGTTCCCCACCTCAGCAAAGCCCACAAGCCCTCCTG CCGAGGGAGCACATTTGGCCACGCAGAGGACGCGGCGTGCGGAGTACTACGACCTCCGGGAATAAGATCA CCTGGCGAGGCTTGAGGGTGTGCACTCGTCCCTTGCACTTTCTGGCGCTGGGCATTTTTTGAATCCACAG GTCATAGGAGGCTAGTGTTAGCAAAATTTATACAGATGTTGTTTTATTTTTATAGCTCTCCTCCATTTAC TGGGTGGCATTTCCTTCAGTGTTAACAACAGAGGTTAACTGCACACAGACGTGCATGGGGATTCTTGCCA GGTTTCTCCCCCTTCCCCTCCTATAAATATGTTTCTCCAGATTGTTCATTCTCTGCCTTGGCTGCAGACG GTCTTTTAGCATTCAGATTTAATTGGTTCAGCCAATTCCTGGGCCATCTGCAGAACTGTGTTTGTTATAA ACACGCCAGTGATTGCATCCTCCGATAAGTGCACATTGAAAGAAATCAAAGGTGTTCTGATGGGATTTTC GACACTTTCAACAGTAGGCATTCTATTCTTTGTTGTAATGCTGTGCGAAGCTCAGCTTCTGTGCTCTCAA GGCAGAAGTGTGTTTACCCCCAACCCCATTCTCAAAGGCCTCTGTTCTTCCCGTTTTTGTAGTTGACTAA ACAGCGTCTGGTGGATGCAGATGGCATCATTAATCCCAGCGCTTTCTACATCTACCTGACGGCTTGGGTC AGCAACGACCCCGTCGCGTATGCTGCCTCCCAGGCCAACATCCGGCCACACCGACCAGAATGGGTCCACG ACAAAGCCGACTACATGCCTGAAACAAGGCTGAGAAGTAAGTAGCGTTTTATCGGGAGGTCTGGGAACTT ACAGAGGTGCCTTCCCTGGTTCTCCAAACTCAGCAACAGCCTTCATCCGTTGACGCTACCCAGGGTTCAG AAGTGTAAACAGAACAATCTATTTCTTCTCGTTTAAAACTCTGGGAGACGAGGATGTGTAATGGGATACA ACCCCCGCACTCTATCACATTGGGAAATCAGTGTCTCGTCTCCATTCGTAGCTTTAATGCTAAGACGTTC ATTAGGCGTTGCTCTCACGTGCCAGCTGTTCCCTGTGAACACCGGGGACGCCTCCAGGTTAAGTGTTATT TTACTATTGCAGAGTTTTATCGCTGGGGATTATATGTTTATCTTAACTTTGTCAACTCTGGTGTTGAAGG GATTTTTGGCACATTGGGTCATTCCTATAAGCCACCAAGCACCTGCACTGTGTCAAAGCTGTTTAAACCG GAGCAGAAAAGTCTGTATACAACAGCGTCCTCTTCCTTTCACCTCTCAGCCCAGAGTTTGAAAGGTGGTT CTGTGTGGATTTCATTTGCATTTCTGGTGGAGATATTAGTAGCGTATGCTTTGGATACCGGGCCAAGGGA GGATGTGAGAAAGAAGACGGGTCCCCTTGCAAACATGGCTGGAGACTCAGCGAGTAGTGCTTCCCCGGAT CCAGTGCTGCCCAGAGCCCTGTGGCAGGCAGCCAAGGCTTGTCTTAATGAAAATTTATAGTTGAGATTAT AATAGGGCAAATCATGTTTAGCAAGTCAACTGAATGACCCCAGAGGGTCTGGAACACACAACGGCAGTAA CTAAATGCTTGTTGTGTAAGGATTTCTTCCCCTGTTGCTGAAGACTTAGCATTGCATTAGAAAAGAAGCA TACAAGGTTGAAGTTTGTTCAGGCACTAAAAGGATAAGTTAAGCATTTTTCTCAGGAAAGCATGACTCTT GAGTTCTTTTGCTCTTGCAAGTGATTGAATAAAACTGTGTGAACTTGGTATTTTCATATGTGTCAAGGGA ACAAAAAAATGTTCCCAAAATGTAAGCCTGGAGTTTTTAGACCCCTCACAAAGAATGACTGCTGGAAGAT TAAAATCAAATCTTAAAAAATACACACATCACAGAGTTAAACATTTTTAAACCAAATGGGAAGATCGTAA AGGCCTGGAGGCTATGATCAGCATTGTTTGTTCTTTGTATCATGTAGAAGAGCAGTCAGTAAGCTTTCAT GCAAAGTTCTTCTCTCTTTCCATTGAAACTGTGATGCTCTTCTACCCTGGGCTGCTCCTAACCTGTGCCC TTCTCTGTCCAGTCCCGGCAGCAGAGCCCATCGAGTATGCCCAGTTCCCTTTCTACCTCAACGGCTTGCG GGACACCTCAGACTTTGTGGAGGCAATTGAAAAAGTAAGGACCATCTGCAGCAACTATACGAGCCTGGGG CTGTCCAGTTACCCCAACGGCTACCCCTTCCTCTTCTGGGAGCAGTACATCGGCCTCCGCCACTGGCTGC TGCTGTTCATCAGCGTGGTGTTGGCCTGCACATTCCTCGTGTGCGCTGTCTTCCTTCTGAACCCCTGGAC GGCCGGGATCATTGTGAGTGTATTATAAGGGGCTTTGTGGAAGTCAAATTCCTTTCAGCATAGCTCTTTC TGCAGCCGGGAAGTTTTGTTTATGTCTGGGCCTCTGGAGGAGGGTATAGCTTGCATCATCCGTAATATGT TTATTCTACTCGAGGTGGTGAGGTCCATGGTTAAGGTAGAACCTCTAATGGCCTTATTCGTAGGTCCTCT CTCCTGTAGCTTGAAGATTTTTGTGGAAAGATAGGGGACTTTTTAAAGCACACCTTCCATCACAGCTCTG AACATTTATTAAATCAAAACACTCAAAGCCTAGCTCATTTTTTCTTTAATTGAAAAGTGTCATTTTGTGA CCTCATCCAGGCCTAATAACGACATAGCAGGTTCTTCTGCATTTAACATGAAGGGACAATCAGAGAAGTT AGGAGAGTGATATATGGAGAAAATGATTTTGTGTGTTTTAAGTCCTGGGGGAAAATGATAAACTAATATT ACGAACCTGTTTTTTGGCATCCCTTCTCCAAAATACTCTCAGATTTTGATGTAAGTTTCATGTAGAGTCT AATAAAACCGTGGCAATGTTTAAATTCTGTGAACTATGGTATAGCCTTTAAAATGCCAAAATTATAAAAA CAAAGGCCAGATTTTGTGTCTGCACCGTGAGTCTGTGCAGCAGGTACATTAAAAGGTAAATGTTTAGTCT GTGAGAGTTTTCATGGCACTTAGCAATTGATGTTGTCCATCTTTCATCATTCCTTCCCCTCCCTCCACCT CTGCCCACCACCCACCCCCAGAGAAGAAAGATCATTTTTCTCCTTCTCTTCCATCTGGTAACTTGTTGTT TATTTGTATCTTCTCCGCTTTGGACCAAGAAACTCCAAATCTAACTCACAGATTTTATTTCCATTTCCCC ACAAATTTTTACAAGGAAGATGAAAGGCAAGAAGCTTTTCCTTGGATTTTAACAGTTGGCTCAGTCCACC CCAGCTGTCCCCAGCTCTTCAAAGTGCAGGGCTCCTGTAACCTGACAGCGTCAGCTGATGACGACCTCCC CGCTTACCTGGCCCCCACATCATCTTTGCTTAGCCTGCAGGTTCACTCACAAAAGCAAAACTACTTTGAC CTGCAAATCTTTTATTCACCCCGTCCTATCAGCTTTCTTTAGAATGGAGAGTGAGGCAACCAAAAACTTA ATGATGGGTTCACGGATGGTCTCTGGCGGCTGAGACCCAAGCAGGAGGAGAGATGGGTCTTGTTGTAAAC TGTGAAATTCGCAGCTAAGTGATGCGGCCATGCTTGTGCAATTCCTCGTGGATTGCGCTGGTGGAGTTGT TCTGTATGTTTTTTGCTTTCTGGAGAAGGTACATTGGAAAATAATTTGCATTAGAACACTCTACTTTGCC TTCTACAGCTTTACACATCAGCTGTCCCACAGTCTCCCTTCCCAGCGGGAAGATGAATTAGGCAGTAAAG GCAGTGTCCAGAGTTAAAGCAAGTCAGTCCATTCATTGTTTTGATCTGAACCGAGGACACCTTAGCCCTC TGGCGACCTCCCTTGTGGGCAGCCCCAGAGGGTGACCTGCCCGCCCACTGACCACTGTGTGCCCTGCTCC AGGTGATGGTCCTGGCGCTGATGACGGTCGAGCTGTTCGGCATGATGGGCCTCATCGGAATCAAGCTCAG TGCCGTGCCCGTGGTCATCCTGATCGCTTCTGTTGGCATAGGAGTGGAGTTCACCGTTCACGTTGCTTTG GTATGGGAGACATTTGAAGCAAAAACTTTGTGAAAAAACAACCCATTTCCTCTGGCTCTGTTTGTCTCCA AGTGGGAACCTTGCATTCTCCCTGTGCGTGGCAGTGAAAAGGCCTCAGGGCACAGGGGCCCCCTAGGAGA GCCTGCAAGATTTCTGGATTCCTTTCCCTCAAGGGAGGCTAAGGAGAGGGGTATGGAAGGTACATGGCAG CGGGCCCTGTCAGCCGTAGGCAGTGCAGGGTTGGTGTGTTGGAGTGGGCCTTGAAGGGCCGTGCTCACCT GACTTTGACTGTCATTATACCCCCACGATTCCTGACGTTGTGACGTTTGTTCATAAGGCGGATTATGTGG TGAGTGTGTGGGTGGGCATACACAGAGTTTTAAAAACAACAGGAACAGTGGGGATAAAATGAGACCACAC TCACAGGCTTGGGGATGGCATCACTGAGGATGAGGTGAGCTGGCAGCCAAGGAAGTACCCTCGGGCTTAG GAGTGGAGGCTCCATTGTTCAGCCCCGGGGAACTGGCTCTTCTACCTAAGCCCACCCAGTTCCTCAGACC TCCCAGCCTCTACATTCATGATAGCAGAAAGTAAGAGAACCAGTGTTGCTTTCAACAGACATTTTTTTCC CTCTCTTTTTCTCTATCTTGCCCTGTGAATGCTTTGTTGGAGGTAATTAAACTTCAGAAGGAATCTTTAG TCCAAGAGATAAATCTGTTGTATACATTTATCAAAGAATTATCCAAAACATCACAACTGTGTAAATTATG TTCTGTCTGCAGATTAGAGCCTAAGAACTTGGGGTTATCAGTAGGCATTCAATAAGTAAATGCGTTCACC TGTTAAATATCGACGTGCGAAATACCCTAGCTAGGAAGCCAGCACTGGGCTTGACCAAATCACTTCCGCC ATTGCTTTTGCAATCTCTAGCACAGGTTTCCTTTGGGCTCAGCACATGGCACATGCATGTCTCCACATAG GCTGCAGCCTTGTGCCTTCTGCAGTCTTTCCAGGGCTACTGTGATACAATTGAGAGATTGTAAACTTTTG TGTTTTGGAAGGAATGCTTTGTTGAAGTTATCCCATTTTTTTTACAGTGTATCATAAAAAGCCAATAATA TGGCAACAGTATTCTCTAAATTTTGAGCCTGCTCAAATTATTTTCTTCCTTTGAGCTGGGAGGAGGGACT ATTTTTTTAAAAAGAAGAGTGCCAGCCTAGAGTTTAGAAAACCCATAATTCCAATACAGTTCTTCAAAAG GGAGATAAATTTGCATGTGAGTTAAGAATCCATAAGTTATTTTATTCTGATGCAAATGGAAACCACCTTT TTTGGAAGCTAGCAGGGCAAATGGGTATCCCAGAGCAGATTTTTACCATGGAAATGCTAACTGCAGTCTC TAAACTCTAGGACTTCTAGTCCAAGTCATTTTCAGTATTCTGATCCTCTATGTGAAATTGCATTTAGAGT TGGCAGTTATTGCTCTTTCAAGGTTTGTAAAATGGTAGAATAAGGCTGTGAAGAAGAGTCTTCTTTCATG AATGTCTTTAGGAAATCAGTGGGTTCCCGTTCATTTGCTGTCTCAGTAACATAGAAACAGTGTGTGACAG GGTAGTCACAACTAGGCCCTTATGGCCTCATGGCCCAAATATGATGCAAGCCAGCATGGCTGAAAAACCC CTTTGGTGCCTTGCCCCAAGAGCAGAAGGCAGCTATATTGACCCTAATGTCTTTACCAACTCTGAAAGAG TAGAACCTGTTTGAGAGAAAAGTATGAAAACTCTTAGCACACCTTTGTATATTTGTATTTTTTCATCTGT TAAGGAGAACGACCGTCTCAGTCCTTCTGCAGGTAGGTAAGGGATAGAAACGCATCCTGCCAAAGACACC CAGCCCTCTCCTCTCGGCATAATCCAGAGCAGCCTGAACTTCAGAGAGAGAACTTGTGCCAGGTTCAACA CTCCCTGCAGGGGTCACACGTTCAGGCCAACAGTCTGATCTTCCAGAATTTACTCTGCAAAGTTCCCGTT TAGTTATCAACAGCATTTCTGGCCTAGGAGAGCTTTAGGACTGCAGGAGAGACAGGGATGTGTCCACACA ATGTTCAGAAGGGCTTGATTCAAATGTACGGTCCTGTGTATTTCTTGCAATACACTCATAGTGCTTAGAT GTACTACAAACATAGCCTGAAACAGTGACAGAAGGTCTCACCTCTGCATAATCGTGAGGAAGTGTGTGTA GCACCCAATTGCTTGGGACACTGAGCTAAGCTCTTAGCCATCCAATGCATTAGCCAGAATCCTGTGCTGT GGGAATTGGAGGTCTCACGTGTGAGTGGTGTGAGATCATTTAAGGAGGGGGGAAACTTCGGGGTGAGTAT CAGTGAAAAGAAGGGGACATTTCTGTCCATTTTTATATAGTTTTGATTTTACTGTGTTCAAGATTTACGT CAACACCAAATATGACCCAGTGTCATGAAGAGGTCATCTTAGTTTAAGTCTAGGTGCTGCTAGTTGAGCT ACTCTGATTACACATTCTAGCAACTAAAACAGTAAGATGTGAGCAGTTCTGAGAGCTTGTAACATTTAGG ACAGAGCTGAGCATTTACCAGGTGAAGTCCAGCAACCTGATCTTGTGAACATCCTCATTGCACAGGCCTT TCTGACGGCCATCGGCGACAAGAACCGCAGGGCTGTGCTTGCCCTGGAGCACATGTTTGCACCCGTCCTG GATGGCGCCGTGTCCACTCTGCTGGGAGTGCTGATGCTGGCGGGATCTGAGTTCGACTTCATTGTCAGGT AAGCAGGCGTGTGCAAGGAGACATGTTTTAGAAATCATTGTGATTGGGCCGGGTGCAGTGGCTCACGCCT GTAATCCCAGCACTTTAGGAGGCCGAGGCGGGTGGATCAGAAGGTCAAGGAGTTCAAGACCAGCCTGGCC AAGATGGTGAAACTCATCTCCACTCAAAATACAAAAATTAGCCGGGCGTGGTGGTGGGTGCCTGTAATCC CAGCTACTTGGGAGGCTGAGGCAGAGAATTGCTCGAACCCGGGAGGCGGAGGTTGCAGTGAGCTGAGATT GCGCCACTACACTCCAGCCTGGGTGACAGAGCGAGATTCTGTCTCAAAAAAAAAAATATTGTTATTAGCT CAGGTGATCTTCGTTGCTTATTTCCTTCTGTATCTGGTAGATTGCAGCACCTCGTCATCGTGACTCTGCT TTCTTTTGAACTTGTTAACGTAGAGATATTCGGAGGTATAAAGACAAGCTCTCTTCTAGAGCTGTCTTGG GGAGTATCTTGAAAACAGAAGGTAAAGGATTTGGGGCTGGCAGCAAAGACAACTCTGCAGCTTGAAGCCA AAGGATCACCCAATAGGTGGCCCATTATTGTCTCGGGTTAGAAACACTGCAGAAAGAAATGCCACATTTG ACCTACGCTCCCTCTCCTTCAAACTGTAGAAAGGAAAACTTAAAAATACCTAAAATTGTCACCTGACTTT ATTCTTTTAAGAAGTGAAAATGACGTGCTCAGATTTCATATTCGAGTCCCCACAATTAGGAAGCATTTAG CATTGGACTTTGGTGTCAACTCTTGGGAATCTAAGCCTAGTTTGGATCTCAAGGCAAGTCGTTTCCAGTT GATTTAATTAAGAATATGACTTTGTGAAATATAAAAGAACAGTGAGTTTTCCTTTTGAAAAGAATTTGAG AACTGCAGAGGAGGAAACCACTTGCTTCTTTGAGCAGCCTCCATGGCTTTGTGAGGGACCTGCTCTTGGA TAGAACTCTGCTACTTTATGGAGCTCTAAGGCCAGAATCACCAATAAGTAAAAGATAGTCCAGGATTAGA ACCATGACAGGGCAGAACCAGATGTGAGAAATGATTGGTTTGTTTGGCACGCTTCAGTACTGAGAGGTTG TGTGTGTGTGTGTGTGTGTGTGTGTGTCAGAGAGAGAGATACGCTTCTTATCTTCAAGTAAAAAGAAGAG GGTTTCAACTAGAAGTTTTAGCCAAAGTTTTATTACGGGAAAGAGATGAGTCCATTGGTTGGCCTGTGGC ATAGCCCACTGGGCAATTTGGCATCATGGAGGCCGCCTTCTTAGAATGAGTGCCAAGCTTGCTTATTGTA GTTTTTGCATAGAGTGAATGGTGAAGTGGAATCGCTGTAGACCAGCGCTTCTCACACCGATGTGCTGAGG AATCATCTGAGGGTCTAAGTGCAGGGCCGATTTCGGGGGGCGGGAGGTGGGATGAGGGCTGGGTCTGCAT CTCCAGCTACCTCCCTGCAATGTCCATGGAGCTAGACTTCTCAGCACAAACTACTGCTAAGCCAGCAAGC CAGTTCCTAAATTCCTGTTTGCCAATACCAAGTAGAGAGTTGCCCAACTGAGTTAAATGTTTTGGTCTGT GTTTTATTTTAGTTCTTAGTTTGATTTTAGCTTTTCCTTTGTTCTTAGTATACACTTTTTCAGGCACTAA CGTTATCATTATGATATAAAAGCTCAATGTCAAGTAGAGTTTCTTTTGCATATTTACTTTCTCGTTTAAC ACAAATATAACAAGCACCCCATAAGTGCCATTTGCACAACAGCAAATAATGGGGACCCCCATATCCCTCT GTGTAGCCTAAGGTCTTTTAGGGGAGAGACAAGTTCACAGGCAAAACCAGGGGAAATGCAAGGTGTGCTG GGGTCTCATGAGTTACAGGAGGGTCTCGCTCAGCCTTGTGGGGGATGCTGAATGAGGAAACTTAGCCTGA ATTAGAGCCCCCAGCTGGAAACCTGGCAGCTGGAATCCCAGCGCTCTCCTCTCAGCCGGGGTTGTTCCCG CCCAGAAATATCAGGGTTCCTCTTTCAAGCACTTAAAAGGGCTTCCCATTTTCTAGGATGGGATGGATTA ACCTGATAAAGGCCTCACCAAGGTCAAATAAATGAGCAGACACTGTATATGCTAAGCCGTCAGAAATCTA ATTGGCCTGTTTATGCTTCAGCTAGATGGATGGGATGCAAATGTCTTAATGTGGCTGCTGATACATGCCC CAGCCGAAAGTTCCAGCAGTTTACATTAGACCAAGACATTGGCTGCTTGGTTTTTACTAATGTAGTTCAG AAGTTTCTAGTGTTTACAATAGCTGTGAGGTATTTGTATTTTTATGGGGATTCTCTCTCCTTTCATCTGA TGTCAAAACATATATAGACATGGCAGCACTGGTTGCCTGTTCCATTTTATGAACCAGAGGACCATTAACA GATAGATATCTTGCCCCCCCCTTCCCAGAACATCCTGAGCCTCTCCCCTACCCCAGCCCACTTCCATCAG AGTTGCCCTAGAAATCATTAGTTCCAGAAACGCATCCCTGCGTGGAGTCTGTGCCCTCCAGCCATGCAGA GTGTCTGCCAGAGGCTGTCCCTGGCTGACAGGTTTACCTTGGTATTCATGAAGGATTCCAGACCTTAGCC CTCAATGGTGGGAAAGCAGAACTACTTCTGCACTCTCCTCCTCTGCCATGGTGCTGCGGCCTTTATGTTT GAATTGGCTGACGCAAAACAAGAGTATTCAGAGATGCTAAATTGTTCAACAAAAGATTGGCCCGCAGAGC AGCCCCGCCATTGTGGAGTGCCCTCACCCAGCACAATGCCCCAGCTCCCACAGAATGGGCAGCATTTTCT TTGCAGAAAGCTGGTTCCTGTGTTCTAAAAAGGTTGCAATTGGAGCTATTTGGTAAAACTGGAACTCACA GAATTCTAGGCAGAAAGTTGTGATTAATGAAAGGCCAGGGAAAGCCTTACCTGATATGCTAGAGACTTAA TTAGAGATTCTGCCGTAAGATGCAGAAGCATTTCACAGTGGATTAGCAGCCTGCAGAAGTGGGCTGCTTT TCCTCCTGGGCTAAATTGTTTAAATTCTACACCCTTCACTTCATTTGTTTGCTTCTGCTGGGTTTTCACG AGCGGGGCCCCTCGGCATTGTGTTTGTGCTTTCAGTCTGCCCAGCCATTCAGGTCGCATTCCATATTTTT GTGTTTGTGTAACACATTCATAAATAACATTACATGCCATCAGAGTTCAGCAAATTAACAAACTAATTTT TTTTTTCTTCCCTTCATGAACTAACACTTTGGGTTGTGGAATGTAGTCCTCAAAGTCATAAGGTAAAGAA ACAAAAAGCAAAAACTCACCTTGTGTTGAATGTGAACTGCGGTTGGATAACAGCCTTTTCAGTGGGGTGG GTTTTGTTCATTTCTGGCGTTGCCATGCTGCTGTGTCGGGCACACGGAGGGTGGCGCGATCCACCCTGTC ACAGCGCGTGTTCCCGTTTCCTCTTGATCTCCCAGGTATTTCTTTGCTGTGCTGGCGATCCTCACCATCC TCGGCGTTCTCAATGGGCTGGTTTTGCTTCCCGTGCTTTTGTCTTTCTTTGGACCATATCCTGAGGTCAG TAGTGACACGGGGATGTCCCACGTGTAGGCCGGCTGAATGCTGTGTTTCCTGTGCCGCTCTTCACTTCGA TACTTAGGTGCCTCCCCACTTGCTGGTGGTTCTTCAGTAAACATCTCAGAGTCATGTCTGTTTTCCTCTT CGGTGTACTGGCTTTGAGGGCTAGAGGGCGGGTTCGGTTTGGTTCCTCTAAATCAACTGATTGGCAGCCT GGGTCTTACAGATCTTTATACAGTAAATGAAGACTTTCCCCTTGAGATGCATAATTGGACTTCACAAGAG TAAAAAGTACACATCCTGCCTTTCCAGTGTGGAGCAGAGGACAGTTCTTCTGCTCCAGCTGCGGGACCTG AAGGTCCTCCAGGTGGTAGAGAAGGGGAGGTTAATACGGCACAGTGCGCAGGGCCCCAGGGCAGGGAACA GAGGCCCCTGAAAAATACCGTGCTTTGAGCTTTGAGTGTGGCCAGCAGGTAAATGGACAAGAACACTTTT AACATGGAATCCCCTTAAATAGGTGTCTCCAGCCAACGGCTTGAACCGCCTGCCCACACCCTCCCCTGAG CCACCCCCCAGCGTGGTCCGCTTCGCCATGCCGCCCGGCCACACGCACAGCGGGTCTGATTCCTCCGACT CGGAGTATAGTTCCCAGACGACAGTGTCAGGCCTCAGCGAGGAGCTTCGGCACTACGAGGCCCAGCAGGG CGCGGGAGGCCCTGCCCACCAAGTGATCGTGGAAGCCACAGAAAACCCCGTCTTCGCCCACTCCACTGTA AGTGACTCTGCAGAACCAGGGGGAGGGGTCTTCCCACCGTGGTAGTGGGCCTGGAGGTCCAGCGGGGGCT CCTGTCTGCTGAGCAGCACATCACACAGGCAGATGGGATGCAGAGATAAGGTACAGACTAGGTCAAATCA TAGGAAATAACCAGTATTTAACTCTTTCTCAACTATACAAATGCCATCTTCCTGTGGTTTGATCTCATAA AGGATAAAAAGGGCAGGGGCCAGTAATGTCACTGCACAAAGCAGTAGCATCTATCTTGTTCAGGGTGAGG ACAGTTTGGGCTTCAAAGGCCAGAGATAAAGCATTCCTGCCTTTTTTTTTTTTTTCCTCTTAAGGTGCAT GTCATTTGAGAGTGATATTTTCTAAAACTAGTAGTATTTTTATTGCCAACAGAGGTCAGGTTTTTTCCTT CTCTCATTTCTGTTAGGTTTCAATGCCCTTGATACAACATTCATTATTATTGTCTAAATACTTTACCATA GCTTTTGGGGCTCCAAGCTCATGTTCCAGGTGGCAGGAAAGAGCAGAGAGGCCAAGAACCACCCCTGAGT TCTTAGCCTTCAGTGATTCAGGAGGTCACCAGGAGCCTGGGAGCCCCTCCTCGGAGGCTCCAAGGACCTG GGTCCTTTCCTCCACCCTGTGCTCCCTGGGATGGGCTCAGCCCTGAAAACTCAAGGAAGGTTCTGGGCTG ATGTTGCTCCACTGAGGGCCCCCTGCTGTCCCTCCAGGAAATGGGTATTCCAGTCCCAGGCCAGAGCAGC CCTTCCGTGAAAGAGAGAAAGGCCAACCAAATAACCTGAATTGTCCTCCTCCTACCCCCCGCGACGACGC CCGCTGAGCTGCAGTGTGAATCTGGTTTTGTTCAGCAGGAGCCTAAAAATAGGTACAAGCTGAACGACTT TGAAGTTGGTCACGGTCCTTTTGATTGATGTGGCCACTGTGTTGCTCTGTGCTTTGTATAGAGACGCAGA GACCAGATTCTTAACAATCAGATGGAACAGGCTGCCCGCCACAGCCCTCCGCAGTGACGAAAATGCCCTC TCTGCTTTCCAGGATGGGAGCCACCGGCCACACGTGGCTGTGGAGCACTTGAAATGTGGCCGGGGCTACC GAGGAGCTGGATTTTGGATTTTAGTTCATTAAAACTTAAGCAACCACATGTCTGGAGCGGCTACTGTGTT TGACAGAGTAGGCAGAGACAGTCCTGCCAGCGTCCTGCACTCAGGCCAGCCAGGGCCGCACACTTAGCAA CTTCGGGAGAGGGGCAGCTCAGAGCCTGCAGAACCTAACAGGGTCGGGGGCAGGTTGTGGGGGGCAGCAG CTTGGATGCTCTGACCACAGCCCACATTTATGGGCAGCAGCAGTACGTGTCCAGCCAGCCGTGTCAGAGA AAGCCTGGAAACAGGATTTTCAAACAACACGCTCCTCCGCCAGGTCCTGGAGGTTATTAGAAGGACAGGC TTTTCTTTTGTGGGTGGAAGGCCCCCATTGGCTCCCCAGGGTTGACTGAGTCTTTGGTGAAACCCAAGGA GGGAAGTGTGGGAGCTGCGGGGACCATGCCCAGCCTGGGATACCACCCTTCTAACCCACCCTCACCCTCT GCAGGTGGTCCATCCCGAATCCAGGCATCACCCACCCTCGAACCCGAGACAGCAGCCCCACCTGGACTCA GGGTCCCTGCCTCCCGGACGGCAAGGCCAGCAGCCCCGCAGGGACCCCCCCAGAGAAGGCTTGTGGCCAC CCCCCTACAGACCGCGCAGAGACGCTTTTGAAATTTCTACTGAAGGGCATTCTGGCCCTAGCAATAGGGC CCGCTGGGGCCCTCGCGGGGCCCGTTCTCACAACCCTCGGAACCCAGCGTCCACTGCCATGGGCAGCTCC GTGCCCGGCTACTGCCAGCCCATCACCACTGTGACGGCTTCTGCCTCCGTGACTGTCGCCGTGCACCCGC CGCCTGTCCCTGGGCCTGGGCGGAACCCCCGAGGGGGACTCTGCCCAGGCTACCCTGAGACTGACCACGG CCTGTTTGAGGACCCCCACGTGCCTTTCCACGTCCGGTGTGAGAGGAGGGATTCGAAGGTGGAAGTCATT GAGCTGCAGGACGTGGAATGCGAGGAGAGGCCCCGGGGAAGCAGCTCCAACTGAGGTGAGTGCCACTGAC AAGGGCAGCCAAGGGACCTAGAGCCAGGCAAAGAGGAGGACAAGGTTCTCCTGGGGTTCTCGGCATCCCC GAGGGGCTGTGGCGCTCGGGCACATCCCACGCTGGACCCCAGTGACCTTTTATCCCCAGAGCAAGGCTGA TGTGTCCAAGCTTTGTCATCCTTGGGGAACCAGTCCAGCTCCACACTGCTCTCTTCCCCCACTGCTAACC TGCGGAGGGTCGGTGCAGCGCCACAAGGACACAAACAGCACCACCTTTTACCAATATTTGCCAGTCTTTA TGGAGGTGCATGCCACAGCGAATTGGTCACATGGGAACGCATCCGTGTAACCAGCCCCCAGATGAAGGGA GAGGTCACAAGCAGCCCCCAGGGACACCTCAGGCCCACACCCCACTCTCGTGATTTCTAATACCAAGGTT ACTGCTGCCTGCTTTTGTACTTTATAAATACGGACTTGCACACCTCTTACTCTGTTCAACTTCCTTTTTT GCTTCCTTTTAAAGGGTGATTAAAATCTGAAGCAAAGAGGCCAAAGATTGGAAACCCCCCACCCCCACCT CTTTCCAGAACTGCTTGAAGAGAACTGGTTGGAGTTATGGAAAAGATGCCCTGTGCCAGGACAGCAGTTC ATTGTTACTGTAACCGATTGTATTATTTTGTTAAATATTTCTATAAATATTTAAGAGATGTACACATGTG TAATATAGGAAGGAAGGATGTAAAGTGGTATGATCTGGGGCTTCTCCACTCCTGCCCCAGAGTGTGGAGG CCACAGTGGGGCCTCTCCGTATTTGTGCATTGGGCTCCGTGCCACAACCAAGCTTCATTAGTCTTAAATT TCAGCATATGTTGCTGCTGCTTAAATATTGTATAATTTACTTGTATAATTCTATGCAAATATTGCTTATG TAATAGGATTATTTTGTAAAGGTTTCTGTTTAAAATATTTTAAATTTGCATATCACAACCCTGTGGTAGT ATGAAATGTTACTGTTAACTTTCAAACACGCTATGCGTGATAATTTTTTTGTTTAATGAGCAGATATGAA GAAAGCACGTTAATCCTGGTGGCTTCTCTAGGTGTCGTTGTGTGCGGTCCTCTTGTTTGGCTGTGCGTGT GAACACGTGTGTGAGTTCACCATGTACTGTACTGTGATTTTTTTTTTGTCTTGTTTTGTTTCTCTACACT GTCTGTAACCTGTAGTAGGCTCTGACCTAGTCAGGCTGGAAGCGTCAGGATATCTTTTCTTCGTGCTGGT GAGGGCTGGCCCTAAACATCCACCTAATCCTTTCAAATCAGCCCGGCAAAAGCTAGACTCTCCTCGTGTC TACGGCATCTCTTATGATCATTGGCTGCCATCCAGGACCCCAATTTGTGCTTCAGGGGGATAATCTCCTT CTCTCGGATCATTGTGATGGATGCTGGAACCTCAGGGTATGGAGCTCACATCAGTTCATCATGGTGGGTG TTAGAGAATTCGGTGACATGCCTAGTGCTGAGCCTTGGCTGGGCCATGAGAGTCTGTATACTCTAAAAAG CATGCAGCATGGTGCCCCTCTTCTGACCAACACACACACGACCCCTCCCCCAACACCCCCAAATTCAAGA GTGGATGTGGCCCTGTCACAGGTAGAAAAACCTATTTAGTTAATTCTTTCTTGGCCCACAGTCTCCCAGA AATGATGTTTTGAGTCCCTATAGTTTAAACTCCCTCTCTTAAATGGAGCAGCTGGTTGAGGCTTTCTAGA TCTGTTTGCATCTTCTTTAAAACTAAGTGGTGAGCATGCATTGTGGTGTAGAGGCAGGCATTATGTAGGA TAAGAGCTCCGGGGGGATTCTTCATGCACCAGTGTTTAGGGTACGTGCTTCCTAAGTAAATCCAAACATT GTCTCCATCCTCCCCGTCATTAGTGCTCTTTCAATGTGATGTGGGAAAGCAGGAGGATGGACACACCCCA CTGAAAGATGTAGGCAGGGGCAGGTCTCTCAACCAGGCATATTTTTAAAAGTTGCTTCTGTACTGGTTCT CTTCTTTTGCTCTGAGGTGTGGGCTCCCTCATCTCGTAACCAGAGACCAGCACATGTCAGGGAAGCACCC AGTGTCGGCTCCCCATCCAAATCCACACCAGCACCTTGTTACAGACAAGAAGTCAGAGGAAAGGGCGGGG TCCCTGCAGGGCTGAAGCCTAAGCTACTGTGAGGCGCTCACGAGTGGCAGCTCCTGTTACTCCCTTTTAA ATTACCTGGGAAATCTTAACAGAAAGGTAATGGGCCCCCAGAAATACCCACAGCATAGTGACCTCAGACC CTGATACTCACCACAAAACTTTTAAGATGCTGATTGGGAGCCGCTTGTGGCTGCTGGGTGTGTGTGTGTG TGTGTGCGTGCGTGCGTGTGTGTGTGTCTCTGCTGGGGACCCTGGCCACCCCCCTGCTGCTGTCTTGGTG CCTGTCACCCACATGGTCTGCCATCCTAACACCCAGCTCTGCTCAGAAAACGTCCTGCGTGGAGGAGGGA TGATGCAGAATTCTGAAGTCGACTTCCCTCTGGCTCCTGGCGTGCCCTCGCTCCCTTCCTGAGCCCAGCT CGTGTTGCGCCGGAGGCTGCGCGGCCCCTGATTTCTGCATGGTGTAGAACTTTCTCCAATAGTCACATTG GCAAAGGGAGAACTGGGGTGGGCGGGGGGTGGGGCTGGCAGGGAATTAGAATTTCTCTCTCTCTTTTAAT AGTTTTATTTTGTCTGTCCTGTTTGTTCATTTGGATGTTTTAATTTTTAAAAAAAAAAAAACTTTGCTGA TATTTATAATTTTGTATCATAAGAATGTTTTCCTCTACAGTATTTGTCATGCCAGTTTATAACAAAAAAA AATGCAGGGATTTTATTTCTATTGGAAACATTACAGCTATGTTTTACTTTTGGACAGAATTTTTATTTGT ATAGAGTGCTTACTAATGTTAAATAGTTCAGAGTATATAACATTTACATTAAGGACTCATGGTAGGTTTT AGGGTAAGGAGTTTAAAGGAAATAAATATTCAAACTGGGTCTCATTGCCAATTTTGGTGGAAATGAGTTT GTGTCATTTCAATTACAAAGATAAAAGTATGCCATATAATTTATTTATATGAAGATTTATTTTTGTAGTG TACATAGTAGTCATCAAGTCTTTTGACAGAAGTATATTTTTAAAGAATTTATATGTGATGAATCCATAAT GTCTGGAACTTTGCTGAGACATGAGTGGGCACAGTTTTCATTGTAAATTACAGCAAGGAAAGAAAATGTT TAACAGTGTTAAGAGAGTCAGAGCAGAGTGGATATTCATGCGATTATGAAGTGTTTATTAGTTACCATTG GCGACCTAGCATGCTTCTCATTTCAAACCTTGGAAGGTGAAAATGTACAAACTCTCTAAATAATTAATGT TCAAACACTGATAGAAATTCTAACATGAATAAAAAATAATATAACTTGTTGGTTATATCTTTGTTTGTAG AATGCTTTTTTTCTTTAAAATACTTGGGAGAGACAGTTAGTGTTGGAGCCATCAGAAACTGTTGTTTCAT CTTGCTGACCTTGTGACACTCTTCTTTTTTGCTCTATCTGATGGAGAGAGTTTTAGGTTTTCCTCCTTTT TGTTTTGTATAAATAGTGGGTATAAGCATAGCTCTGTTACATGGATGTATTACAAAGTGGGGGCTGAGCT TTTAGTGTGATCATCACCCAAATAGTGTACATTGTACCCATTAATTAATTTCTTATCACCTGACCCTATT TTTGTTTTCTCATACCAAGAAACTTCCTAAGTTAACCATCAAAATTAGTCCTTCTGTCATCTCTCTTAGC ATACTTATTTCCCTTATGTGATGCCTAATAATGAGGGAACATAAATAAAGCCAAATTCAAAGAT Download Select all
Length	73984
OMIM ID	601309
HGNC ID	HGNC:9585
Unigene ID	Hs.494538
Ensembl ID	ENSG00000185920
PharmGKB ID	-

mRNA Information

mRNA ID	NM_001083603.1
Exon	join(1..343,10367..10559,31092..31281,34763..34832, 34926..35017,36378..36576,36876..36997,37819..37966, 38780..38911,39264..39419,40109..40207,40807..40932, 47035..47153,47813..48215,49541..49850,54968..55110, 57183..57366,58673..58953,60553..60690,63346..63488, 67026..67125,67643..67897,69515..70055,70575..73984)
mRNA Sequence	>5727 GCGCCCGCCGTGTGAGCAGCAGCAGCGGCTGGTCTGTCAACCGGAGCCCGAGCCCGAGCAGCCT GCGGCCAGCAGCGTCCTCGCAAGCCGAGCGCCCAGGCGCGCCAGGAGCCCGCAGCAGCGGCAGC AGCGCGCCGGGCCGCCCGGGAAGCCTCCGTCCCCGCGGCGGCGGCGGCGGCGGCGGCAACATGG CCTCGGCTGGTAACGCCGCCGAGCCCCAGGACCGCGGCGGCGGCGGCAGCGGCTGTATCGGTGC CCCGGGACGGCCGGCTGGAGGCGGGAGGCGCAGACGGACGGGGGGGCTGCGCCGTGCTGCCGCG CCGGACCGGGACTATCTGCACCGGCCCAGCTACTGCGACGCCGCCTTCGCTCTGGAGCAGATTT CCAAGGGGAAGGCTACTGGCCGGAAAGCGCCGCTGTGGCTGAGAGCGAAGTTTCAGAGACTCTT ATTTAAACTGGGTTGTTACATTCAAAAAAACTGCGGCAAGTTCTTGGTTGTGGGCCTCCTCATA TTTGGGGCCTTCGCGGTGGGATTAAAAGCAGCGAACCTCGAGACCAACGTGGAGGAGCTGTGGG TGGAAGTTGGAGGACGAGTAAGTCGTGAATTAAATTATACTCGCCAGAAGATTGGAGAAGAGGC TATGTTTAATCCTCAACTCATGATACAGACCCCTAAAGAAGAAGGTGCTAATGTCCTGACCACA GAAGCGCTCCTACAACACCTGGACTCGGCACTCCAGGCCAGCCGTGTCCATGTATACATGTACA ACAGGCAGTGGAAATTGGAACATTTGTGTTACAAATCAGGAGAGCTTATCACAGAAACAGGTTA CATGGATCAGATAATAGAATATCTTTACCCTTGTTTGATTATTACACCTTTGGACTGCTTCTGG GAAGGGGCGAAATTACAGTCTGGGACAGCATACCTCCTAGGTAAACCTCCTTTGCGGTGGACAA ACTTCGACCCTTTGGAATTCCTGGAAGAGTTAAAGAAAATAAACTATCAAGTGGACAGCTGGGA GGAAATGCTGAATAAGGCTGAGGTTGGTCATGGTTACATGGACCGCCCCTGCCTCAATCCGGCC GATCCAGACTGCCCCGCCACAGCCCCCAACAAAAATTCAACCAAACCTCTTGATATGGCCCTTG TTTTGAATGGTGGATGTCATGGCTTATCCAGAAAGTATATGCACTGGCAGGAGGAGTTGATTGT GGGTGGCACAGTCAAGAACAGCACTGGAAAACTCGTCAGCGCCCATGCCCTGCAGACCATGTTC CAGTTAATGACTCCCAAGCAAATGTACGAGCACTTCAAGGGGTACGAGTATGTCTCACACATCA ACTGGAACGAGGACAAAGCGGCAGCCATCCTGGAGGCCTGGCAGAGGACATATGTGGAGGTGGT TCATCAGAGTGTCGCACAGAACTCCACTCAAAAGGTGCTTTCCTTCACCACCACGACCCTGGAC GACATCCTGAAATCCTTCTCTGACGTCAGTGTCATCCGCGTGGCCAGCGGCTACTTACTCATGC TCGCCTATGCCTGTCTAACCATGCTGCGCTGGGACTGCTCCAAGTCCCAGGGTGCCGTGGGGCT GGCTGGCGTCCTGCTGGTTGCACTGTCAGTGGCTGCAGGACTGGGCCTGTGCTCATTGATCGGA ATTTCCTTTAACGCTGCAACAACTCAGGTTTTGCCATTTCTCGCTCTTGGTGTTGGTGTGGATG ATGTTTTTCTTCTGGCCCACGCCTTCAGTGAAACAGGACAGAATAAAAGAATCCCTTTTGAGGA CAGGACCGGGGAGTGCCTGAAGCGCACAGGAGCCAGCGTGGCCCTCACGTCCATCAGCAATGTC ACAGCCTTCTTCATGGCCGCGTTAATCCCAATTCCCGCTCTGCGGGCGTTCTCCCTCCAGGCAG CGGTAGTAGTGGTGTTCAATTTTGCCATGGTTCTGCTCATTTTTCCTGCAATTCTCAGCATGGA TTTATATCGACGCGAGGACAGGAGACTGGATATTTTCTGCTGTTTTACAAGCCCCTGCGTCAGC AGAGTGATTCAGGTTGAACCTCAGGCCTACACCGACACACACGACAATACCCGCTACAGCCCCC CACCTCCCTACAGCAGCCACAGCTTTGCCCATGAAACGCAGATTACCATGCAGTCCACTGTCCA GCTCCGCACGGAGTACGACCCCCACACGCACGTGTACTACACCACCGCTGAGCCGCGCTCCGAG ATCTCTGTGCAGCCCGTCACCGTGACACAGGACACCCTCAGCTGCCAGAGCCCAGAGAGCACCA GCTCCACAAGGGACCTGCTCTCCCAGTTCTCCGACTCCAGCCTCCACTGCCTCGAGCCCCCCTG TACGAAGTGGACACTCTCATCTTTTGCTGAGAAGCACTATGCTCCTTTCCTCTTGAAACCAAAA GCCAAGGTAGTGGTGATCTTCCTTTTTCTGGGCTTGCTGGGGGTCAGCCTTTATGGCACCACCC GAGTGAGAGACGGGCTGGACCTTACGGACATTGTACCTCGGGAAACCAGAGAATATGACTTTAT TGCTGCACAATTCAAATACTTTTCTTTCTACAACATGTATATAGTCACCCAGAAAGCAGACTAC CCGAATATCCAGCACTTACTTTACGACCTACACAGGAGTTTCAGTAACGTGAAGTATGTCATGT TGGAAGAAAACAAACAGCTTCCCAAAATGTGGCTGCACTACTTCAGAGACTGGCTTCAGGGACT TCAGGATGCATTTGACAGTGACTGGGAAACCGGGAAAATCATGCCAAACAATTACAAGAATGGA TCAGACGATGGAGTCCTTGCCTACAAACTCCTGGTGCAAACCGGCAGCCGCGATAAGCCCATCG ACATCAGCCAGTTGACTAAACAGCGTCTGGTGGATGCAGATGGCATCATTAATCCCAGCGCTTT CTACATCTACCTGACGGCTTGGGTCAGCAACGACCCCGTCGCGTATGCTGCCTCCCAGGCCAAC ATCCGGCCACACCGACCAGAATGGGTCCACGACAAAGCCGACTACATGCCTGAAACAAGGCTGA GAATCCCGGCAGCAGAGCCCATCGAGTATGCCCAGTTCCCTTTCTACCTCAACGGCTTGCGGGA CACCTCAGACTTTGTGGAGGCAATTGAAAAAGTAAGGACCATCTGCAGCAACTATACGAGCCTG GGGCTGTCCAGTTACCCCAACGGCTACCCCTTCCTCTTCTGGGAGCAGTACATCGGCCTCCGCC ACTGGCTGCTGCTGTTCATCAGCGTGGTGTTGGCCTGCACATTCCTCGTGTGCGCTGTCTTCCT TCTGAACCCCTGGACGGCCGGGATCATTGTGATGGTCCTGGCGCTGATGACGGTCGAGCTGTTC GGCATGATGGGCCTCATCGGAATCAAGCTCAGTGCCGTGCCCGTGGTCATCCTGATCGCTTCTG TTGGCATAGGAGTGGAGTTCACCGTTCACGTTGCTTTGGCCTTTCTGACGGCCATCGGCGACAA GAACCGCAGGGCTGTGCTTGCCCTGGAGCACATGTTTGCACCCGTCCTGGATGGCGCCGTGTCC ACTCTGCTGGGAGTGCTGATGCTGGCGGGATCTGAGTTCGACTTCATTGTCAGGTATTTCTTTG CTGTGCTGGCGATCCTCACCATCCTCGGCGTTCTCAATGGGCTGGTTTTGCTTCCCGTGCTTTT GTCTTTCTTTGGACCATATCCTGAGGTGTCTCCAGCCAACGGCTTGAACCGCCTGCCCACACCC TCCCCTGAGCCACCCCCCAGCGTGGTCCGCTTCGCCATGCCGCCCGGCCACACGCACAGCGGGT CTGATTCCTCCGACTCGGAGTATAGTTCCCAGACGACAGTGTCAGGCCTCAGCGAGGAGCTTCG GCACTACGAGGCCCAGCAGGGCGCGGGAGGCCCTGCCCACCAAGTGATCGTGGAAGCCACAGAA AACCCCGTCTTCGCCCACTCCACTGTGGTCCATCCCGAATCCAGGCATCACCCACCCTCGAACC CGAGACAGCAGCCCCACCTGGACTCAGGGTCCCTGCCTCCCGGACGGCAAGGCCAGCAGCCCCG CAGGGACCCCCCCAGAGAAGGCTTGTGGCCACCCCCCTACAGACCGCGCAGAGACGCTTTTGAA ATTTCTACTGAAGGGCATTCTGGCCCTAGCAATAGGGCCCGCTGGGGCCCTCGCGGGGCCCGTT CTCACAACCCTCGGAACCCAGCGTCCACTGCCATGGGCAGCTCCGTGCCCGGCTACTGCCAGCC CATCACCACTGTGACGGCTTCTGCCTCCGTGACTGTCGCCGTGCACCCGCCGCCTGTCCCTGGG CCTGGGCGGAACCCCCGAGGGGGACTCTGCCCAGGCTACCCTGAGACTGACCACGGCCTGTTTG AGGACCCCCACGTGCCTTTCCACGTCCGGTGTGAGAGGAGGGATTCGAAGGTGGAAGTCATTGA GCTGCAGGACGTGGAATGCGAGGAGAGGCCCCGGGGAAGCAGCTCCAACTGAGGGTGATTAAAA TCTGAAGCAAAGAGGCCAAAGATTGGAAACCCCCCACCCCCACCTCTTTCCAGAACTGCTTGAA GAGAACTGGTTGGAGTTATGGAAAAGATGCCCTGTGCCAGGACAGCAGTTCATTGTTACTGTAA CCGATTGTATTATTTTGTTAAATATTTCTATAAATATTTAAGAGATGTACACATGTGTAATATA GGAAGGAAGGATGTAAAGTGGTATGATCTGGGGCTTCTCCACTCCTGCCCCAGAGTGTGGAGGC CACAGTGGGGCCTCTCCGTATTTGTGCATTGGGCTCCGTGCCACAACCAAGCTTCATTAGTCTT AAATTTCAGCATATGTTGCTGCTGCTTAAATATTGTATAATTTACTTGTATAATTCTATGCAAA TATTGCTTATGTAATAGGATTATTTTGTAAAGGTTTCTGTTTAAAATATTTTAAATTTGCATAT CACAACCCTGTGGTAGTATGAAATGTTACTGTTAACTTTCAAACACGCTATGCGTGATAATTTT TTTGTTTAATGAGCAGATATGAAGAAAGCACGTTAATCCTGGTGGCTTCTCTAGGTGTCGTTGT GTGCGGTCCTCTTGTTTGGCTGTGCGTGTGAACACGTGTGTGAGTTCACCATGTACTGTACTGT GATTTTTTTTTTGTCTTGTTTTGTTTCTCTACACTGTCTGTAACCTGTAGTAGGCTCTGACCTA GTCAGGCTGGAAGCGTCAGGATATCTTTTCTTCGTGCTGGTGAGGGCTGGCCCTAAACATCCAC CTAATCCTTTCAAATCAGCCCGGCAAAAGCTAGACTCTCCTCGTGTCTACGGCATCTCTTATGA TCATTGGCTGCCATCCAGGACCCCAATTTGTGCTTCAGGGGGATAATCTCCTTCTCTCGGATCA TTGTGATGGATGCTGGAACCTCAGGGTATGGAGCTCACATCAGTTCATCATGGTGGGTGTTAGA GAATTCGGTGACATGCCTAGTGCTGAGCCTTGGCTGGGCCATGAGAGTCTGTATACTCTAAAAA GCATGCAGCATGGTGCCCCTCTTCTGACCAACACACACACGACCCCTCCCCCAACACCCCCAAA TTCAAGAGTGGATGTGGCCCTGTCACAGGTAGAAAAACCTATTTAGTTAATTCTTTCTTGGCCC ACAGTCTCCCAGAAATGATGTTTTGAGTCCCTATAGTTTAAACTCCCTCTCTTAAATGGAGCAG CTGGTTGAGGCTTTCTAGATCTGTTTGCATCTTCTTTAAAACTAAGTGGTGAGCATGCATTGTG GTGTAGAGGCAGGCATTATGTAGGATAAGAGCTCCGGGGGGATTCTTCATGCACCAGTGTTTAG GGTACGTGCTTCCTAAGTAAATCCAAACATTGTCTCCATCCTCCCCGTCATTAGTGCTCTTTCA ATGTGATGTGGGAAAGCAGGAGGATGGACACACCCCACTGAAAGATGTAGGCAGGGGCAGGTCT CTCAACCAGGCATATTTTTAAAAGTTGCTTCTGTACTGGTTCTCTTCTTTTGCTCTGAGGTGTG GGCTCCCTCATCTCGTAACCAGAGACCAGCACATGTCAGGGAAGCACCCAGTGTCGGCTCCCCA TCCAAATCCACACCAGCACCTTGTTACAGACAAGAAGTCAGAGGAAAGGGCGGGGTCCCTGCAG GGCTGAAGCCTAAGCTACTGTGAGGCGCTCACGAGTGGCAGCTCCTGTTACTCCCTTTTAAATT ACCTGGGAAATCTTAACAGAAAGGTAATGGGCCCCCAGAAATACCCACAGCATAGTGACCTCAG ACCCTGATACTCACCACAAAACTTTTAAGATGCTGATTGGGAGCCGCTTGTGGCTGCTGGGTGT GTGTGTGTGTGTGTGCGTGCGTGCGTGTGTGTGTGTCTCTGCTGGGGACCCTGGCCACCCCCCT GCTGCTGTCTTGGTGCCTGTCACCCACATGGTCTGCCATCCTAACACCCAGCTCTGCTCAGAAA ACGTCCTGCGTGGAGGAGGGATGATGCAGAATTCTGAAGTCGACTTCCCTCTGGCTCCTGGCGT GCCCTCGCTCCCTTCCTGAGCCCAGCTCGTGTTGCGCCGGAGGCTGCGCGGCCCCTGATTTCTG CATGGTGTAGAACTTTCTCCAATAGTCACATTGGCAAAGGGAGAACTGGGGTGGGCGGGGGGTG GGGCTGGCAGGGAATTAGAATTTCTCTCTCTCTTTTAATAGTTTTATTTTGTCTGTCCTGTTTG TTCATTTGGATGTTTTAATTTTTAAAAAAAAAAAAACTTTGCTGATATTTATAATTTTGTATCA TAAGAATGTTTTCCTCTACAGTATTTGTCATGCCAGTTTATAACAAAAAAAAATGCAGGGATTT TATTTCTATTGGAAACATTACAGCTATGTTTTACTTTTGGACAGAATTTTTATTTGTATAGAGT GCTTACTAATGTTAAATAGTTCAGAGTATATAACATTTACATTAAGGACTCATGGTAGGTTTTA GGGTAAGGAGTTTAAAGGAAATAAATATTCAAACTGGGTCTCATTGCCAATTTTGGTGGAAATG AGTTTGTGTCATTTCAATTACAAAGATAAAAGTATGCCATATAATTTATTTATATGAAGATTTA TTTTTGTAGTGTACATAGTAGTCATCAAGTCTTTTGACAGAAGTATATTTTTAAAGAATTTATA TGTGATGAATCCATAATGTCTGGAACTTTGCTGAGACATGAGTGGGCACAGTTTTCATTGTAAA TTACAGCAAGGAAAGAAAATGTTTAACAGTGTTAAGAGAGTCAGAGCAGAGTGGATATTCATGC GATTATGAAGTGTTTATTAGTTACCATTGGCGACCTAGCATGCTTCTCATTTCAAACCTTGGAA GGTGAAAATGTACAAACTCTCTAAATAATTAATGTTCAAACACTGATAGAAATTCTAACATGAA TAAAAAATAATATAACTTGTTGGTTATATCTTTGTTTGTAGAATGCTTTTTTTCTTTAAAATAC TTGGGAGAGACAGTTAGTGTTGGAGCCATCAGAAACTGTTGTTTCATCTTGCTGACCTTGTGAC ACTCTTCTTTTTTGCTCTATCTGATGGAGAGAGTTTTAGGTTTTCCTCCTTTTTGTTTTGTATA AATAGTGGGTATAAGCATAGCTCTGTTACATGGATGTATTACAAAGTGGGGGCTGAGCTTTTAG TGTGATCATCACCCAAATAGTGTACATTGTACCCATTAATTAATTTCTTATCACCTGACCCTAT TTTTGTTTTCTCATACCAAGAAACTTCCTAAGTTAACCATCAAAATTAGTCCTTCTGTCATCTC TCTTAGCATACTTATTTCCCTTATGTGATGCCTAATAATGAGGGAACATAAATAAAGCCAAATT CAAAGATAAAAAAAAAAAAAA Download Select all
Length	7957

CDS Information

Location	join(146..343,10367..10559,31092..31281,34763..34832, 34926..35017,36378..36576,36876..36997,37819..37966, 38780..38911,39264..39419,40109..40207,40807..40932, 47035..47153,47813..48215,49541..49850,54968..55110, 57183..57366,58673..58953,60553..60690,63346..63488, 67026..67125,67643..67897,69515..70054)
CDS Sequence	>lcl\|NM_000264.3_cds_NP_000255.2_1 [gene=PTCH1] [protein=protein patched homolog 1 isoform L] [protein_id=NP_000255.2] [location=189..4532] ATGGCCTCGGCTGGTAACGCCGCCGAGCCCCAGGACCGCGGCGGCGGCGGCAGCGGCTGTATCGGTGCCC CGGGACGGCCGGCTGGAGGCGGGAGGCGCAGACGGACGGGGGGGCTGCGCCGTGCTGCCGCGCCGGACCG GGACTATCTGCACCGGCCCAGCTACTGCGACGCCGCCTTCGCTCTGGAGCAGATTTCCAAGGGGAAGGCT ACTGGCCGGAAAGCGCCGCTGTGGCTGAGAGCGAAGTTTCAGAGACTCTTATTTAAACTGGGTTGTTACA TTCAAAAAAACTGCGGCAAGTTCTTGGTTGTGGGCCTCCTCATATTTGGGGCCTTCGCGGTGGGATTAAA AGCAGCGAACCTCGAGACCAACGTGGAGGAGCTGTGGGTGGAAGTTGGAGGACGAGTAAGTCGTGAATTA AATTATACTCGCCAGAAGATTGGAGAAGAGGCTATGTTTAATCCTCAACTCATGATACAGACCCCTAAAG AAGAAGGTGCTAATGTCCTGACCACAGAAGCGCTCCTACAACACCTGGACTCGGCACTCCAGGCCAGCCG TGTCCATGTATACATGTACAACAGGCAGTGGAAATTGGAACATTTGTGTTACAAATCAGGAGAGCTTATC ACAGAAACAGGTTACATGGATCAGATAATAGAATATCTTTACCCTTGTTTGATTATTACACCTTTGGACT GCTTCTGGGAAGGGGCGAAATTACAGTCTGGGACAGCATACCTCCTAGGTAAACCTCCTTTGCGGTGGAC AAACTTCGACCCTTTGGAATTCCTGGAAGAGTTAAAGAAAATAAACTATCAAGTGGACAGCTGGGAGGAA ATGCTGAATAAGGCTGAGGTTGGTCATGGTTACATGGACCGCCCCTGCCTCAATCCGGCCGATCCAGACT GCCCCGCCACAGCCCCCAACAAAAATTCAACCAAACCTCTTGATATGGCCCTTGTTTTGAATGGTGGATG TCATGGCTTATCCAGAAAGTATATGCACTGGCAGGAGGAGTTGATTGTGGGTGGCACAGTCAAGAACAGC ACTGGAAAACTCGTCAGCGCCCATGCCCTGCAGACCATGTTCCAGTTAATGACTCCCAAGCAAATGTACG AGCACTTCAAGGGGTACGAGTATGTCTCACACATCAACTGGAACGAGGACAAAGCGGCAGCCATCCTGGA GGCCTGGCAGAGGACATATGTGGAGGTGGTTCATCAGAGTGTCGCACAGAACTCCACTCAAAAGGTGCTT TCCTTCACCACCACGACCCTGGACGACATCCTGAAATCCTTCTCTGACGTCAGTGTCATCCGCGTGGCCA GCGGCTACTTACTCATGCTCGCCTATGCCTGTCTAACCATGCTGCGCTGGGACTGCTCCAAGTCCCAGGG TGCCGTGGGGCTGGCTGGCGTCCTGCTGGTTGCACTGTCAGTGGCTGCAGGACTGGGCCTGTGCTCATTG ATCGGAATTTCCTTTAACGCTGCAACAACTCAGGTTTTGCCATTTCTCGCTCTTGGTGTTGGTGTGGATG ATGTTTTTCTTCTGGCCCACGCCTTCAGTGAAACAGGACAGAATAAAAGAATCCCTTTTGAGGACAGGAC CGGGGAGTGCCTGAAGCGCACAGGAGCCAGCGTGGCCCTCACGTCCATCAGCAATGTCACAGCCTTCTTC ATGGCCGCGTTAATCCCAATTCCCGCTCTGCGGGCGTTCTCCCTCCAGGCAGCGGTAGTAGTGGTGTTCA ATTTTGCCATGGTTCTGCTCATTTTTCCTGCAATTCTCAGCATGGATTTATATCGACGCGAGGACAGGAG ACTGGATATTTTCTGCTGTTTTACAAGCCCCTGCGTCAGCAGAGTGATTCAGGTTGAACCTCAGGCCTAC ACCGACACACACGACAATACCCGCTACAGCCCCCCACCTCCCTACAGCAGCCACAGCTTTGCCCATGAAA CGCAGATTACCATGCAGTCCACTGTCCAGCTCCGCACGGAGTACGACCCCCACACGCACGTGTACTACAC CACCGCTGAGCCGCGCTCCGAGATCTCTGTGCAGCCCGTCACCGTGACACAGGACACCCTCAGCTGCCAG AGCCCAGAGAGCACCAGCTCCACAAGGGACCTGCTCTCCCAGTTCTCCGACTCCAGCCTCCACTGCCTCG AGCCCCCCTGTACGAAGTGGACACTCTCATCTTTTGCTGAGAAGCACTATGCTCCTTTCCTCTTGAAACC AAAAGCCAAGGTAGTGGTGATCTTCCTTTTTCTGGGCTTGCTGGGGGTCAGCCTTTATGGCACCACCCGA GTGAGAGACGGGCTGGACCTTACGGACATTGTACCTCGGGAAACCAGAGAATATGACTTTATTGCTGCAC AATTCAAATACTTTTCTTTCTACAACATGTATATAGTCACCCAGAAAGCAGACTACCCGAATATCCAGCA CTTACTTTACGACCTACACAGGAGTTTCAGTAACGTGAAGTATGTCATGTTGGAAGAAAACAAACAGCTT CCCAAAATGTGGCTGCACTACTTCAGAGACTGGCTTCAGGGACTTCAGGATGCATTTGACAGTGACTGGG AAACCGGGAAAATCATGCCAAACAATTACAAGAATGGATCAGACGATGGAGTCCTTGCCTACAAACTCCT GGTGCAAACCGGCAGCCGCGATAAGCCCATCGACATCAGCCAGTTGACTAAACAGCGTCTGGTGGATGCA GATGGCATCATTAATCCCAGCGCTTTCTACATCTACCTGACGGCTTGGGTCAGCAACGACCCCGTCGCGT ATGCTGCCTCCCAGGCCAACATCCGGCCACACCGACCAGAATGGGTCCACGACAAAGCCGACTACATGCC TGAAACAAGGCTGAGAATCCCGGCAGCAGAGCCCATCGAGTATGCCCAGTTCCCTTTCTACCTCAACGGC TTGCGGGACACCTCAGACTTTGTGGAGGCAATTGAAAAAGTAAGGACCATCTGCAGCAACTATACGAGCC TGGGGCTGTCCAGTTACCCCAACGGCTACCCCTTCCTCTTCTGGGAGCAGTACATCGGCCTCCGCCACTG GCTGCTGCTGTTCATCAGCGTGGTGTTGGCCTGCACATTCCTCGTGTGCGCTGTCTTCCTTCTGAACCCC TGGACGGCCGGGATCATTGTGATGGTCCTGGCGCTGATGACGGTCGAGCTGTTCGGCATGATGGGCCTCA TCGGAATCAAGCTCAGTGCCGTGCCCGTGGTCATCCTGATCGCTTCTGTTGGCATAGGAGTGGAGTTCAC CGTTCACGTTGCTTTGGCCTTTCTGACGGCCATCGGCGACAAGAACCGCAGGGCTGTGCTTGCCCTGGAG CACATGTTTGCACCCGTCCTGGATGGCGCCGTGTCCACTCTGCTGGGAGTGCTGATGCTGGCGGGATCTG AGTTCGACTTCATTGTCAGGTATTTCTTTGCTGTGCTGGCGATCCTCACCATCCTCGGCGTTCTCAATGG GCTGGTTTTGCTTCCCGTGCTTTTGTCTTTCTTTGGACCATATCCTGAGGTGTCTCCAGCCAACGGCTTG AACCGCCTGCCCACACCCTCCCCTGAGCCACCCCCCAGCGTGGTCCGCTTCGCCATGCCGCCCGGCCACA CGCACAGCGGGTCTGATTCCTCCGACTCGGAGTATAGTTCCCAGACGACAGTGTCAGGCCTCAGCGAGGA GCTTCGGCACTACGAGGCCCAGCAGGGCGCGGGAGGCCCTGCCCACCAAGTGATCGTGGAAGCCACAGAA AACCCCGTCTTCGCCCACTCCACTGTGGTCCATCCCGAATCCAGGCATCACCCACCCTCGAACCCGAGAC AGCAGCCCCACCTGGACTCAGGGTCCCTGCCTCCCGGACGGCAAGGCCAGCAGCCCCGCAGGGACCCCCC CAGAGAAGGCTTGTGGCCACCCCCCTACAGACCGCGCAGAGACGCTTTTGAAATTTCTACTGAAGGGCAT TCTGGCCCTAGCAATAGGGCCCGCTGGGGCCCTCGCGGGGCCCGTTCTCACAACCCTCGGAACCCAGCGT CCACTGCCATGGGCAGCTCCGTGCCCGGCTACTGCCAGCCCATCACCACTGTGACGGCTTCTGCCTCCGT GACTGTCGCCGTGCACCCGCCGCCTGTCCCTGGGCCTGGGCGGAACCCCCGAGGGGGACTCTGCCCAGGC TACCCTGAGACTGACCACGGCCTGTTTGAGGACCCCCACGTGCCTTTCCACGTCCGGTGTGAGAGGAGGG ATTCGAAGGTGGAAGTCATTGAGCTGCAGGACGTGGAATGCGAGGAGAGGCCCCGGGGAAGCAGCTCCAA CTGA Download Select all
CCDS ID	CCDS47995.1

Protein Information

Protein ID	NP_000255.2
Protein Name	patched 1
Molecular Wt. (Da)	160414
Protein Sequence	>5727 MASAGNAAEPQDRGGGGSGCIGAPGRPAGGGRRRRTGGLRRAAAPDRDYLHRPSYCDAAFALEQ ISKGKATGRKAPLWLRAKFQRLLFKLGCYIQKNCGKFLVVGLLIFGAFAVGLKAANLETNVEEL WVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLDSALQASRVHVYM YNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLRW TNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPADPDCPATAPNKNSTKPLDMA LVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHALQTMFQLMTPKQMYEHFKGYEYVSH INWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTTTLDDILKSFSDVSVIRVASGYLL MLAYACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVGV DDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQ AAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYS PPPPYSSHSFAHETQITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPES TSSTRDLLSQFSDSSLHCLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGT TRVRDGLDLTDIVPRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHRSFSNVKYV MLEENKQLPKMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKP IDISQLTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETR LRIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQYIGL RHWLLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAVPVVILIA SVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYF FAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEPPPSVVRFAMPPGHTHS GSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHHPPS NPRQQPHLDSGSLPPGRQGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGA RSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVAVHPPPVPGPGRNPRGGLCPGYPETDHGL FEDPHVPFHVRCERRDSKVEVIELQDVECEERPRGSSSN Download Select all
Length	1447
Uniprot ID	P04196
Ensembl Protein ID	ENSP00000232003

Post-translational Modification Information (Source : HPRD)

No matching records could be found.

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING) View

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
891	CCNB1	454	NP_114172.1	in vivo	9926943
3549	IHH	2839	NP_002172.2	in vivo	9811851
6469	SHH	2838	NP_000184.1	in vivo	9811851

Pathway Information

Pathway Name	Pathway ID
Basal cell carcinoma	hsa05217
cAMP signaling pathway	hsa04024
Hedgehog signaling pathway	hsa04340
Pathways in cancer	hsa05200
Proteoglycans in cancer	hsa05205

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
pfam12349	462-616	Sterol-sensing
cl21543	462-616	MMPL superfamily
pfam03176	467-598	MMPL
pfam07698	1025-1161	7TM-7TMR_HD
cl22453	1025-1161	7TM-7TMR_HD superfamily
TIGR00918	43-1206	2A060602
TIGR00917	398-1179	2A060601
pfam02460	384-1180	Patched
COG1033	469-606	COG1033
COG1033	400-597	COG1033
COG1033	1034-1158	COG1033
TIGR00921	429-612	2A067
TIGR00921	469-596	2A067
COG1033	1030-1161	COG1033
COG0841	1030-1158	AcrB
TIGR00921	1041-1151	2A067
COG2409	467-598	YdfJ
PHA03377	1253-1369	PHA03377
TIGR03480	401-596	HpnN
COG4258	431-594	COG4258
TIGR00833	406-598	actII
TIGR00921	1036-1161	2A067
TIGR00833	1027-1155	actII
pfam09770	1228-1428	PAT1
PHA03307	1229-1363	PHA03307
TIGR00833	469-602	actII

Ontology Information

HPRD ID	6784
Molecular Class	Cell surface receptor
Molecular Function	Chaperone activity (GO:0003754)
Biological Process	Protein metabolism (GO:0019538)

SNP Information

View SNP Geneview Report

Drug Information

No matching records could be found.

External Links

ArrayExpress GO
ICGC GO
Cancer3D GO
COSMIC GO
NCG GO
TSGene GO
Tumor Gene Family of Databases GO
CCDB GO
G2SBC GO
Osteosarcoma Database GO
RCDB GO

ArrayExpress	GO
ICGC	GO
Cancer3D	GO
COSMIC	GO
NCG	GO
TSGene	GO
Tumor Gene Family of Databases	GO
CCDB	GO
G2SBC	GO
Osteosarcoma Database	GO
RCDB	GO

CoReCG

Search results:

General Information

Evidence Information

Gene Details

mRNA Information

CDS Information

Protein Information

Post-translational Modification Information (Source : HPRD)

Enzyme Information

PPi Information

Pathway Information

Structure Information

Domain Information

Ontology Information

SNP Information

Drug Information

External Links

Important Information