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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
RAET1L 154064 Retinoic acid early transcript 1L  6ULBP6 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
22930170   2012Cell line : KM 12C, KM 12SM, HT 29

Source : ATCC

Sample Type : -

No. of Sample : -

Stage : -

Microarray analysis,Real time RT-PCR and Flow cytometryUp-regulation-Gene differentially expressed and analysed bye by Microarray.


Gene Details



Chromosome: 6; NC_000006.11 (150341266..150346668, complement)

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Gene Type protein coding
Gene Family -
Description RAET1L belongs to the RAET1 family of major histocompatibility complex (MHC) class I-related genes, which are located within a 180-kb cluster on chromosome 6q24.2-q25.3. The REAT1 genes encode glycoproteins that contain extracellular alpha-1 and alpha-2 domains, but they lack the membrane proximal Ig-like alpha-3 domain. Most RAET1 glycoproteins are anchored to the membrane via glycosylphosphatidylinositol (GPI) linkage (Radosavljevic et al., 2002 [PubMed 11827464]).[supplied by OMIM, Mar 2008]  
Chromosome 6
Location 6q25.1
Start 150018342  
End 150025596  
Strand -  
Gene Sequence

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Length 7255  
OMIM ID 611047   
HGNC ID HGNC:16798   
Unigene ID Hs.558659    
Ensembl ID ENSG00000155918   
PharmGKB ID -   

mRNA Information


mRNA ID XM_011535486.1
Exon join(1..210,3354..3617,4411..4692,5358..5489,6742..7255)  
mRNA Sequence

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Length 1402  



CDS Information


   
Locationjoin(126..210,3354..3617,4411..4692,5358..5467)
CDS Sequence

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CCDS ID CCDS5224.1



Protein Information


      
Protein IDNP_570970.2
Protein NameRetinoic acid early transcript 1L
Molecular Wt. (Da)21857
Protein Sequence

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Length 246  
Uniprot IDQ14332
Ensembl Protein ID ENSP00000323901  



Post-translational Modification Information (Source : HPRD)


No matching records could be found.

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

No matching records from HPRD source could be found.

Pathway Information


      
Pathway Name Pathway ID
Natural killer cell mediated cytotoxicity hsa04650


Structure Information


No matching records could be found.

Domain Information




ID Location Description
pfam1458629-198  MHC_I_2
cl0824629-198  MHC_I superfamily
pfam0012930-198  MHC_I


Ontology Information


   
HPRD ID11817
Molecular ClassMHC complex protein
Molecular FunctionCarboxy-lyase activity (GO:0016831)
Biological ProcessMetabolism (GO:0008152); Energy pathways (GO:0006091)  



SNP Information


View SNP Geneview Report   

Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO