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General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| RASSF2 | 9770 | Ras association (RalGDS/AF-6) domain family member 2 | 20 | KIAA0168, CENP-34 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 24519048 | 2014 | Cell line : - Source : - Sample Type : Serum samples No. of Sample : 59 CRC and 59 healthy volunteers Stage : - | Methylation specific PCR | Methylation | - | Methylation in promoter region of RASSF2 and sFRP1 is often detected in serum of colorectal cancer patients. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | This gene encodes a protein that contains a Ras association domain. Similar to its cattle and sheep counterparts, this gene is located near the prion gene. Two alternatively spliced transcripts encoding the same isoform have been reported. [provided by RefSeq, Jul 2008 | Chromosome | 20 |
| Location | 20p13 |
| Start | 4760669 |
| End | 4804291 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 43623 |
| OMIM ID | 609492 |
| HGNC ID | HGNC:9883 |
| Unigene ID | Hs.631504 |
| Ensembl ID | ENSG00000101265 |
| PharmGKB ID | PA34246 |
Protein Information
| Protein ID | NP_055552.1 |
|---|---|
| Protein Name | Ras association (RalGDS/AF-6) domain family member 2 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 326 |
| Uniprot ID | Q15043 |
| Ensembl Protein ID | ENSP00000240095 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 145 |
| S | Phosphorylation | 69 |
| S | Phosphorylation | 145 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 3265 | HRAS | 1813 | NP_005334.1 | in vivo | 12732644 |
| 3845 | KRAS | 1817 | NP_203524.1 | in vitro;in vivo | 12732644 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd01784 | 177-263 | rasfadin_RA |
| cl00155 | 177-263 | UBQ superfamily |
| cd01768 | 178-263 | RA |
| smart00314 | 174-263 | RA |
| pfam00788 | 180-264 | RA |
| cd01782 | 193-246 | AF6_RA_repeat1 |
| cd01778 | 180-263 | RASSF1_RA |
Ontology Information
| HPRD ID | 5522 |
|---|---|
| Molecular Class | Cell cycle control protein |
| Molecular Function | Transcription regulator activity (GO:0030528) |
| Biological Process | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219) |
Drug Information
No matching records could be found.