Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| REPIN1 | 29803 | replication initiator 1 | 7 | RIP60, AP4, H_DJ0584D14.12, Zfp464 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 23752226 | 2013 | Cell line : - Source : - Sample Type : - No. of Sample : - Stage : - | Microarray, genome-wide chromatin immunoprecipitation, next-generation sequencing | Up-regulation | - | Elevated AP4 expression in primary CRC significantly correlated with liver metastasis and poor patient survival. These findings imply AP4 as a new regulator of EMT that contributes to metastatic processes in CRC and presumably other carcinomas. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Zinc fingers, C2H2-type |
| Description | - | Chromosome | 7 |
| Location | 7q36.1 |
| Start | 150368229 |
| End | 150374044 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 5816 |
| OMIM ID | |
| HGNC ID | HGNC:17922 |
| Unigene ID | Hs.647086 |
| Ensembl ID | ENSG00000214022 |
| PharmGKB ID | - |
mRNA Information
| mRNA ID | XM_011516111.1 |
|---|---|
| Exon | join(1..90,1443..5815) | mRNA Sequence | Download Select all |
| Length | 3185 |
CDS Information
| Location | join(1484..1640,3000..4717) |
|---|---|
| CDS Sequence | Download Select all |
| CCDS ID | CCDS47745.1 |
Protein Information
| Protein ID | NP_001093166.1 |
|---|---|
| Protein Name | replication initiator 1 |
| Molecular Wt. (Da) | 63444 |
| Protein Sequence | Download Select all |
| Length | 567 |
| Uniprot ID | P13646 |
| Ensembl Protein ID | ENSP00000246635 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 27 |
| S | Phosphorylation | 27 |
| K | Acetylation | 33 |
| K | Acetylation | 33 |
| K | Acetylation | 276 |
| K | Acetylation | 276 |
| S | Phosphorylation | 329 |
| S | Phosphorylation | 329 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam13465 | 473-498 | zf-H2C2_2 |
| cl22375 | 473-498 | zf-H2C2_2 superfamily |
| pfam13465 | 278-303 | zf-H2C2_2 |
| cl22375 | 278-303 | zf-H2C2_2 superfamily |
| pfam13465 | 250-275 | zf-H2C2_2 |
| cl22375 | 250-275 | zf-H2C2_2 superfamily |
| pfam13465 | 501-526 | zf-H2C2_2 |
| cl22375 | 501-526 | zf-H2C2_2 superfamily |
| pfam13465 | 417-442 | zf-H2C2_2 |
| cl22375 | 417-442 | zf-H2C2_2 superfamily |
| pfam13465 | 390-412 | zf-H2C2_2 |
| cl22375 | 390-412 | zf-H2C2_2 superfamily |
| pfam00096 | 487-509 | zf-C2H2 |
| cl23491 | 487-509 | zf-C2H2 superfamily |
| COG5048 | 233-565 | COG5048 |
| COG5048 | 254-540 | COG5048 |
| COG5048 | 235-424 | COG5048 |
| COG5048 | 138-312 | COG5048 |
| PHA00733 | 514-567 | PHA00733 |
Ontology Information
| HPRD ID | 1019 |
|---|---|
| Molecular Class | DNA binding protein |
| Molecular Function | Structural constituent of cytoskeleton (GO:0005200) |
| Biological Process | Cell growth and/or maintenance (GO:0008151) |
Drug Information
No matching records could be found.