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General Information
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
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Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 20331631 | 2010 | Cell line : - Source : - Sample Type : CRC tumor and normal tissue No. of Sample : 115 Stage : - | - | Up-regulation | - | Resistin and visfatin may be good biomarkers of colorectal malignant potential and stage progression. Resistin and visfatin levels in cancer patients were significantly higher than those of controls on multivariate analysis (P = 0.03 and P < 0.01, respectively). Stage progression significantly correlated with resistin and visfatin levels (P < 0.01 for both). |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | |
| Description | This gene belongs to the family defined by the mouse resistin-like genes. The characteristic feature of this family is the C-terminal stretch of 10 cys residues with identical spacing. The mouse homolog of this protein is secreted by adipocytes, and may be the hormone potentially linking obesity to type II diabetes. Alternatively spliced transcript variants encoding the same protein have been found for this gene. | Chromosome | 19 |
| Location | 19p13.2 |
| Start | 7669086 |
| End | 7670454 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 1369 |
| OMIM ID | 605565 |
| HGNC ID | HGNC:20389 |
| Unigene ID | Hs.283091 |
| Ensembl ID | ENSG00000104918 |
| PharmGKB ID | - |
mRNA Information
| mRNA ID | NM_020415.3 |
|---|---|
| Exon | join(1..36,232..359,736..813,1134..1369) | mRNA Sequence | Download Select all |
| Length | 469 |
CDS Information
| Location | join(242..359,736..813,1134..1264) |
|---|---|
| CDS Sequence | Download Select all |
| CCDS ID | CCDS12182.1 |
Protein Information
| Protein ID | NP_001180303.1 |
|---|---|
| Protein Name | resistin |
| Molecular Wt. (Da) | 9554 |
| Protein Sequence | Download Select all |
| Length | 108 |
| Uniprot ID | P07195 |
| Ensembl Protein ID | ENSP00000229319 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 8175 | SF3A2 | 2877 | NP_009096.2 | in vitro | 8211113 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam06954 | 18-106 | Resistin |
| cl06143 | 18-106 | Resistin superfamily |
Ontology Information
| HPRD ID | 6091 |
|---|---|
| Molecular Class | Peptide hormone |
| Molecular Function | Receptor activity (GO:0004872) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.