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General Information
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 19806790 | 2009 | Cell line : Colo320D, HT 29 Source : - Sample Type : - No. of Sample : - Stage : - | RT-PCR | Up-regulation | - | RIN1 mRNA was found to be expressed in gastric and colon cancer cell lines, suggesting that it is an important gene for the function of cancer cells. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | - | Chromosome | 11 |
| Location | 11q13.2 |
| Start | 66099535 |
| End | 66104000 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 4466 |
| OMIM ID | 605965 |
| HGNC ID | HGNC:18749 |
| Unigene ID | Hs.1030 |
| Ensembl ID | - |
| PharmGKB ID | PA38671 |
Protein Information
| Protein ID | NP_004283.2 |
|---|---|
| Protein Name | Ras and Rab interactor 1 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 783 |
| Uniprot ID | Q8WWZ7 |
| Ensembl Protein ID | ENSP00000376443 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| Y | Phosphorylation | 36 |
| S | Phosphorylation | 351;- |
| S | Phosphorylation | 210 |
| T | Phosphorylation | 251 |
| S | Phosphorylation | 258 |
| T | Phosphorylation | 253 |
| S | Phosphorylation | 337 |
| S | Phosphorylation | 609 |
| S | Phosphorylation | 333 |
| Y | Phosphorylation | 35 |
| S | Phosphorylation | 3 |
| S | Phosphorylation | 11 |
| S | Phosphorylation | 16 |
| S | Phosphorylation | 356 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 25 | ABL1 | 1809 | NP_009297.2 | in vitro | 914 417 115 886 098 |
| 27 | ABL2 | 1259 | NP_009298.1 | in vivo | 15886098 |
| 3265 | HRAS | 1813 | NP_005334.1 | in vitro;yeast 2-hybrid | 91 441 717 862 125 |
| 5868 | RAB5A | 1542 | NP_004153.2 | in vitro;in vivo;yeast 2-hybrid | 11703925 |
| 5869 | RAB5B | 1544 | NP_002859.1 | in vitro;yeast 2-hybrid | 11703925 |
| 7529 | YWHAB | 3184 | NP_003395.1 | in vitro;in vivo | 117 848 669 144 171 |
| 7531 | YWHAE | 5457 | NP_006752.1 | in vitro;in vivo | 117 848 669 144 171 |
| 7534 | YWHAZ | 3183 | NP_003397.1 | in vitro | 9144171 |
| 22800 | RRAS2 | 2518 | NP_036382.2 | in vivo;yeast 2-hybrid | 11788587 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Ras signaling pathway | hsa04014 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd10393 | 58-158 | SH2_RIN1 |
| cl15255 | 58-158 | SH2 superfamily |
| cd10339 | 58-158 | SH2_RIN_family |
| smart00167 | 489-607 | VPS9 |
| cl19569 | 489-607 | VPS9 superfamily |
| cd01776 | 627-704 | Rin1_RA |
| cl00155 | 627-704 | UBQ superfamily |
| pfam02204 | 492-580 | VPS9 |
| cd10394 | 60-155 | SH2_RIN2 |
| cd10395 | 60-158 | SH2_RIN3 |
| smart00314 | 624-703 | RA |
| smart00252 | 81-153 | SH2 |
| cd01768 | 627-680 | RA |
| cd09927 | 82-161 | SH2_Tensin_like |
| cd00173 | 81-148 | SH2 |
| pfam00788 | 628-686 | RA |
| cd10382 | 82-145 | SH2_SOCS1 |
| pfam04632 | 337-417 | FUSC |
Ontology Information
| HPRD ID | 5783 |
|---|---|
| Molecular Class | Unclassified |
| Molecular Function | Protein binding (GO:0005515) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.