Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| ROCK2 | 9475 | Rho-associated, coiled-coil containing protein kinase 2 | 2 | - |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 23328676 | 2013 | Cell line : - Source : - Sample Type : CRC Tumor and normal tissue No. of Sample : 85 CRC and 178 healthy controls Stage : - | Immunohistochemistry | Polymorhpism | - | ROCK1 and ROCK2 genes might be a risk factor for CRC development and that genetic polymorphisms in these genes may modify individual susceptibility to CRC in the Turkish population. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Pleckstrin homology (PH) domain containing |
| Description | The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. [provided by RefSeq, Jul 2008] | Chromosome | 2 |
| Location | 2p24 |
| Start | 11319894 |
| End | 11484711 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 164818 |
| OMIM ID | 604002 |
| HGNC ID | HGNC:10252 |
| Unigene ID | Hs.681743 |
| Ensembl ID | ENSG00000134318 |
| PharmGKB ID | PA34624 |
Protein Information
| Protein ID | NP_004841.2 |
|---|---|
| Protein Name | Rho-associated, coiled-coil containing protein kinase 2 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 1388 |
| Uniprot ID | O94885 |
| Ensembl Protein ID | ENSP00000356437 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 1134 |
| S | Phosphorylation | 1137 |
| S | Phosphorylation | 425;- |
| T | Phosphorylation | 1078;- |
| S | Phosphorylation | 1361;- |
| S | Phosphorylation | 1362;- |
| S | Phosphorylation | 1132 |
| S | Phosphorylation | 1133 |
| S | Phosphorylation | 1121 |
| S | Phosphorylation | 1374 |
| Y | Phosphorylation | 722 |
| T | Phosphorylation | 567 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 4659 | PPP1R12A | 3606 | NP_002471.1 | in vitro | 1 256 301 212 220 640 000 000 000 000 000 000 000 000 |
| 6780 | STAU1 | 3422 | NP_059347.2 | in vitro | 15121898 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Axon guidance | hsa04360 |
| cAMP signaling pathway | hsa04024 |
| cGMP-PKG signaling pathway | hsa04022 |
| Chemokine signaling pathway | hsa04062 |
| Focal adhesion | hsa04510 |
| Leukocyte transendothelial migration | hsa04670 |
| Oxytocin signaling pathway | hsa04921 |
| Pathogenic Escherichia coli infection | hsa05130 |
| Pathways in cancer | hsa05200 |
| Platelet activation | hsa04611 |
| Proteoglycans in cancer | hsa05205 |
| Regulation of actin cytoskeleton | hsa04810 |
| Salmonella infection | hsa05132 |
| Shigellosis | hsa05131 |
| Sphingolipid signaling pathway | hsa04071 |
| Vascular smooth muscle contraction | hsa04270 |
| Wnt signaling pathway | hsa04310 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd05621 | 39-417 | STKc_ROCK2 |
| cl21453 | 39-417 | PKc_like superfamily |
| cd01242 | 1151-1257 | PH_ROCK |
| cl17171 | 1151-1257 | PH-like superfamily |
| cd11638 | 505-571 | HR1_ROCK2 |
| cl00087 | 505-571 | HR1 superfamily |
| cd00029 | 1261-1307 | C1 |
| cl00040 | 1261-1307 | C1 superfamily |
| cd05596 | 65-416 | STKc_ROCK |
| cd05622 | 25-422 | STKc_ROCK1 |
| cd05573 | 90-416 | STKc_ROCK_NDR_like |
| cd05597 | 90-415 | STKc_DMPK_like |
| cd05601 | 90-415 | STKc_CRIK |
| cd05624 | 26-421 | STKc_MRCK_beta |
| cd05599 | 90-415 | STKc_NDR_like |
| cd05623 | 26-424 | STKc_MRCK_alpha |
| cd05598 | 91-417 | STKc_LATS |
| cd05123 | 98-354 | STKc_AGC |
| cd05629 | 90-417 | STKc_NDR_like_fungal |
| cd05579 | 98-359 | STKc_MAST_like |
| cd05580 | 90-386 | STKc_PKA_like |
| cd05627 | 90-417 | STKc_NDR2 |
| cd05600 | 83-415 | STKc_Sid2p_like |
| cd05628 | 90-417 | STKc_NDR1 |
| cd05626 | 95-392 | STKc_LATS2 |
| cd05570 | 96-416 | STKc_PKC |
| cd05574 | 91-380 | STKc_phototropin_like |
| cd14209 | 90-387 | STKc_PKA |
| cd05609 | 91-359 | STKc_MAST |
| cd05625 | 95-391 | STKc_LATS1 |
| cd05581 | 90-354 | STKc_PDK1 |
| cd05611 | 95-359 | STKc_Rim15_like |
| cd05612 | 90-389 | STKc_PRKX_like |
| cd05584 | 96-415 | STKc_p70S6K |
| cd05575 | 96-415 | STKc_SGK |
| cd05572 | 98-359 | STKc_cGK |
| cd05592 | 96-415 | STKc_nPKC_theta_like |
| cd05571 | 96-386 | STKc_PKB |
| cd05117 | 91-353 | STKc_CAMK |
| cd05585 | 97-386 | STKc_YPK1_like |
| cd05587 | 96-415 | STKc_cPKC |
| cd05578 | 92-354 | STKc_Yank1 |
| cd05589 | 95-418 | STKc_PKN |
| cd14007 | 91-355 | STKc_Aurora |
| cd05582 | 96-415 | STKc_RSK_N |
| cd05595 | 96-386 | STKc_PKB_beta |
| cd05590 | 96-415 | STKc_nPKC_eta |
| cd05591 | 96-417 | STKc_nPKC_epsilon |
| cd05586 | 98-385 | STKc_Sck1_like |
| cd05610 | 90-385 | STKc_MASTL |
| cd05619 | 86-385 | STKc_nPKC_theta |
| cd14003 | 91-353 | STKc_AMPK-like |
| cd05616 | 91-415 | STKc_cPKC_beta |
| cd05602 | 88-385 | STKc_SGK1 |
| cd05604 | 95-385 | STKc_SGK3 |
| cd05614 | 91-384 | STKc_MSK2_N |
| cd05583 | 97-356 | STKc_MSK_N |
| cd14014 | 92-309 | STKc_PknB_like |
| cd05620 | 96-385 | STKc_nPKC_delta |
| cd05122 | 91-354 | PKc_STE |
| cd05603 | 96-385 | STKc_SGK2 |
| cd05615 | 86-415 | STKc_cPKC_alpha |
| cd05588 | 96-385 | STKc_aPKC |
| cd05593 | 91-386 | STKc_PKB_gamma |
| cd05613 | 91-373 | STKc_MSK1_N |
| cd14008 | 98-354 | STKc_LKB1_CaMKK |
| cd06606 | 91-354 | STKc_MAPKKK |
| cd14099 | 90-354 | STKc_PLK |
| cd00180 | 98-287 | PKc |
| cd05577 | 98-374 | STKc_GRK |
| cd05594 | 91-386 | STKc_PKB_alpha |
| cd05618 | 90-385 | STKc_aPKC_iota |
| cd05605 | 96-359 | STKc_GRK4_like |
| cd06623 | 90-356 | PKc_MAPKK_plant_like |
| cd08215 | 91-307 | STKc_Nek |
| cd05617 | 90-385 | STKc_aPKC_zeta |
| cd14663 | 91-353 | STKc_SnRK3 |
| cd14009 | 98-353 | STKc_ATG1_ULK_like |
| cd14118 | 98-352 | STKc_CAMKK |
| cd14069 | 90-354 | STKc_Chk1 |
| cd14081 | 92-354 | STKc_BRSK1_2 |
| cd14098 | 91-353 | STKc_Rad53_Cds1 |
| cd14084 | 92-352 | STKc_Chk2 |
| cd05606 | 97-373 | STKc_beta_ARK |
| cd05630 | 96-356 | STKc_GRK6 |
| cd14095 | 92-352 | STKc_DCKL |
| cd14162 | 92-354 | STKc_TSSK4-like |
| cd14002 | 90-353 | STKc_STK36 |
| cd05632 | 96-356 | STKc_GRK5 |
| cd05631 | 96-356 | STKc_GRK4 |
| cd05608 | 96-374 | STKc_GRK1 |
| cd13999 | 98-294 | STKc_MAP3K-like |
| cd14091 | 91-356 | STKc_RSK_C |
| cd08530 | 91-307 | STKc_CNK2-like |
| cd14006 | 98-352 | STKc_MLCK-like |
| cd14083 | 92-352 | STKc_CaMKI |
| cd14078 | 92-352 | STKc_MELK |
| cd05607 | 96-374 | STKc_GRK7 |
| cd14080 | 92-354 | STKc_TSSK-like |
| cd14166 | 90-364 | STKc_CaMKI_gamma |
| cd06614 | 92-355 | STKc_PAK |
| cd14223 | 91-392 | STKc_GRK2 |
| cd08529 | 91-307 | STKc_FA2-like |
| cd05118 | 92-354 | STKc_CMGC |
| cd14116 | 86-353 | STKc_Aurora-A |
| cd05633 | 86-392 | STKc_GRK3 |
| cd14200 | 92-353 | STKc_CaMKK1 |
| cd14093 | 90-354 | STKc_PhKG |
| cd14096 | 90-353 | STKc_RCK1-like |
| cd08217 | 91-354 | STKc_Nek2 |
| cd06609 | 90-297 | STKc_MST3_like |
| cd14004 | 91-354 | STKc_PASK |
| cd14167 | 90-353 | STKc_CaMKI_alpha |
| cd14073 | 92-294 | STKc_NUAK |
| cd14119 | 98-354 | STKc_LKB1 |
| cd14185 | 92-353 | STKc_DCKL3 |
| cd14072 | 92-299 | STKc_MARK |
| cd14092 | 96-363 | STKc_MSK_C |
| cd06612 | 90-295 | STKc_MST1_2 |
| cd14117 | 90-355 | STKc_Aurora-B_like |
| cd13994 | 98-354 | STKc_HAL4_like |
| cd14074 | 92-353 | STKc_SNRK |
| cd14079 | 92-354 | STKc_AMPK_alpha |
| cd14094 | 90-356 | STKc_CASK |
| cd14086 | 90-356 | STKc_CaMKII |
| cd06605 | 90-355 | PKc_MAPKK |
| cd06610 | 90-354 | STKc_OSR1_SPAK |
| cd14103 | 98-352 | STKc_MLCK |
| cd14071 | 92-354 | STKc_SIK |
| cd14199 | 92-353 | STKc_CaMKK2 |
| cd06627 | 98-354 | STKc_Cdc7_like |
| cd14169 | 92-357 | STKc_CaMKI_beta |
| cd14181 | 90-354 | STKc_PhKG2 |
| cd06625 | 96-354 | STKc_MEKK3_like |
| cd06626 | 96-353 | STKc_MEKK4 |
| cd08219 | 91-298 | STKc_Nek3 |
| cd14131 | 91-353 | PKc_Mps1 |
| cd06613 | 91-295 | STKc_MAP4K3_like |
| cd14089 | 91-352 | STKc_MAPKAPK |
| cd07833 | 90-307 | STKc_CDKL |
| cd14662 | 92-353 | STKc_SnRK2 |
| cd14665 | 92-353 | STKc_SnRK2-3 |
| cd14075 | 92-359 | STKc_NIM1 |
| cd08224 | 91-299 | STKc_Nek6_7 |
| cd14175 | 92-353 | STKc_RSK1_C |
| cd14186 | 90-353 | STKc_PLK4 |
| cd06632 | 96-353 | STKc_MEKK1_plant |
| cd14087 | 92-334 | STKc_PSKH1 |
| cd08218 | 92-307 | STKc_Nek1 |
| cd14137 | 92-298 | STKc_GSK3 |
| cd06659 | 90-354 | STKc_PAK6 |
| cd06648 | 90-355 | STKc_PAK_II |
| cd13978 | 98-329 | STKc_RIP |
| cd08225 | 92-299 | STKc_Nek5 |
| cd14178 | 89-359 | STKc_RSK3_C |
| cd14090 | 97-353 | STKc_Mnk |
| cd14188 | 96-354 | STKc_PLK2 |
| cd14107 | 92-354 | STKc_obscurin_rpt1 |
| cd14076 | 92-353 | STKc_Kin4 |
| cd14010 | 98-353 | STKc_ULK4 |
| cd14082 | 96-353 | STKc_PKD |
| cd13996 | 89-289 | STKc_EIF2AK |
| cd06629 | 96-353 | STKc_Bck1_like |
| cd14121 | 98-353 | STKc_ULK3 |
| cd14171 | 90-353 | STKc_MAPKAPK5 |
| cd06608 | 89-294 | STKc_myosinIII_N_like |
| cd05576 | 86-354 | STKc_RPK118_like |
| cd14077 | 91-353 | STKc_Kin1_2 |
| cd14184 | 90-353 | STKc_DCKL2 |
| cd14161 | 92-294 | STKc_NUAK2 |
| cd14182 | 90-355 | STKc_PhKG1 |
| cd08220 | 91-352 | STKc_Nek8 |
| cd06917 | 92-297 | STKc_NAK1_like |
| cd14046 | 91-326 | STKc_EIF2AK4_GCN2_rpt2 |
| cd14085 | 92-355 | STKc_CaMKIV |
| cd06630 | 96-297 | STKc_MEKK1 |
| cd14106 | 89-354 | STKc_DRAK |
| cd07832 | 91-290 | STKc_CCRK |
| cd14168 | 90-369 | STKc_CaMKI_delta |
| cd13993 | 92-313 | STKc_Pat1_like |
| cd14176 | 92-358 | STKc_RSK2_C |
| cd13987 | 98-293 | STKc_SBK1 |
| cd06620 | 87-355 | PKc_Byr1_like |
| cd08222 | 92-353 | STKc_Nek11 |
| cd08228 | 91-299 | STKc_Nek6 |
| cd14202 | 97-354 | STKc_ULK1 |
| cd14174 | 96-355 | STKc_Mnk1 |
| cd06622 | 93-358 | PKc_PBS2_like |
| pfam08912 | 979-1046 | Rho_Binding |
| cl07487 | 979-1046 | Rho_Binding superfamily |
| cd14120 | 98-333 | STKc_ULK1_2-like |
| cd14070 | 92-308 | STKc_HUNK |
| cd14191 | 92-354 | STKc_MLCK1 |
| cd06652 | 96-353 | STKc_MEKK2 |
| cd07831 | 92-288 | STKc_MOK |
| cd07830 | 92-287 | STKc_MAK_like |
| cd14165 | 92-354 | STKc_TSSK1_2-like |
| cd14177 | 89-294 | STKc_RSK4_C |
| cd06653 | 96-353 | STKc_MEKK3_like_u1 |
| cd06658 | 98-355 | STKc_PAK5 |
| cd06644 | 90-287 | STKc_STK10 |
| cd06624 | 97-353 | STKc_ASK |
| cd06615 | 90-293 | PKc_MEK |
| cd14183 | 89-357 | STKc_DCKL1 |
| cd06611 | 89-293 | STKc_SLK_like |
| cd14187 | 96-354 | STKc_PLK1 |
| cd14172 | 90-353 | STKc_MAPKAPK3 |
| cd13997 | 91-290 | PKc_Wee1_like |
| cd08221 | 92-288 | STKc_Nek9 |
| cd07838 | 92-354 | STKc_CDK4_6_like |
| cd07829 | 92-308 | STKc_CDK_like |
| cd14050 | 92-286 | PKc_Myt1 |
| cd06651 | 96-353 | STKc_MEKK3 |
| cd14189 | 96-354 | STKc_PLK3 |
| cd06639 | 89-355 | STKc_myosinIIIB_N |
| cd14180 | 98-347 | STKc_MSK2_C |
| cd06641 | 98-293 | STKc_MST3 |
| cd08528 | 91-310 | STKc_Nek10 |
| cd14179 | 96-334 | STKc_MSK1_C |
| cd14005 | 92-354 | STKc_PIM |
| cd08223 | 91-310 | STKc_Nek4 |
| cd06642 | 98-329 | STKc_STK25 |
| cd06657 | 98-354 | STKc_PAK4 |
| cd14114 | 92-354 | STKc_Twitchin_like |
| cd14113 | 92-335 | STKc_Trio_C |
| cd06638 | 89-294 | STKc_myosinIIIA_N |
| cd14109 | 90-354 | PK_Unc-89_rpt1 |
| cd06640 | 98-329 | STKc_MST4 |
| cd06647 | 92-355 | STKc_PAK_I |
| cd06656 | 76-355 | STKc_PAK3 |
| cd08229 | 91-299 | STKc_Nek7 |
| cd14115 | 98-353 | STKc_Kalirin_C |
| cd14173 | 96-353 | STKc_Mnk2 |
| cd14163 | 92-354 | STKc_TSSK3-like |
| cd14058 | 98-307 | STKc_TAK1 |
| cd06628 | 97-294 | STKc_Byr2_like |
| cd11626 | 506-571 | HR1_ROCK |
| cd06650 | 86-293 | PKc_MEK1 |
| cd06643 | 90-287 | STKc_SLK |
| cd14097 | 92-333 | STKc_STK33 |
| cd06636 | 92-294 | STKc_MAP4K4_6_N |
| cd06621 | 98-297 | PKc_Pek1_like |
| cd06616 | 98-294 | PKc_MKK4 |
| cd07840 | 92-294 | STKc_CDK9_like |
| cd14111 | 99-310 | STKc_SPEG_rpt2 |
| cd07834 | 92-388 | STKc_MAPK |
| cd14201 | 91-355 | STKc_ULK2 |
| cd14052 | 91-286 | PTKc_Wee1_fungi |
| cd06655 | 76-355 | STKc_PAK2 |
| cd14192 | 95-333 | STKc_MLCK3 |
| cd14194 | 90-353 | STKc_DAPK1 |
| cd07841 | 92-307 | STKc_CDK7 |
| cd07846 | 90-314 | STKc_CDKL2_3 |
| cd14196 | 88-353 | STKc_DAPK2 |
| cd13990 | 92-353 | STKc_TLK |
| cd06654 | 76-355 | STKc_PAK1 |
| cd14190 | 96-354 | STKc_MLCK2 |
| cd06649 | 86-293 | PKc_MEK2 |
| cd14105 | 88-353 | STKc_DAPK |
| cd06631 | 97-353 | STKc_YSK4 |
| cd00192 | 96-294 | PTKc |
| cd06646 | 90-295 | STKc_MAP4K5 |
| cd06645 | 90-295 | STKc_MAP4K3 |
| cd14170 | 90-353 | STKc_MAPKAPK2 |
| cd07866 | 88-290 | STKc_BUR1 |
| cd14108 | 92-354 | STKc_SPEG_rpt1 |
| cd14164 | 92-333 | STKc_TSSK6-like |
| cd06637 | 92-356 | STKc_TNIK |
| cd14104 | 92-355 | STKc_Titin |
| cd14198 | 96-306 | STKc_DRAK2 |
| cd06618 | 81-355 | PKc_MKK7 |
| cd08216 | 93-355 | PK_STRAD |
| cd06619 | 90-294 | PKc_MKK5 |
| cd14193 | 96-333 | STKc_MLCK4 |
| cd07848 | 92-298 | STKc_CDKL5 |
| cd13979 | 97-297 | STKc_Mos |
| cd14088 | 92-375 | STKc_CaMK_like |
| cd13989 | 98-294 | STKc_IKK |
| cd07852 | 92-308 | STKc_MAPK15-like |
| cd07847 | 90-290 | STKc_CDKL1_4 |
| cd07855 | 89-308 | STKc_ERK5 |
| cd14047 | 90-288 | STKc_EIF2AK2_PKR |
| cd14065 | 98-288 | PKc_LIMK_like |
| cd13985 | 92-304 | STKc_GAK_like |
| cd07851 | 92-329 | STKc_p38 |
| cd14048 | 89-288 | STKc_EIF2AK3_PERK |
| cd14025 | 98-294 | STKc_RIP4_like |
| cd14197 | 90-354 | STKc_DRAK1 |
| cd14221 | 98-288 | STKc_LIMK1 |
| cd14016 | 92-258 | STKc_CK1 |
| cd07849 | 89-290 | STKc_ERK1_2_like |
| cd11639 | 507-571 | HR1_ROCK1 |
| cd13991 | 98-341 | STKc_NIK |
| cd13988 | 98-294 | STKc_TBK1 |
| cd14154 | 98-288 | STKc_LIMK |
| cd14132 | 90-295 | STKc_CK2_alpha |
| cd14019 | 90-300 | STKc_Cdc7 |
| cd07860 | 95-298 | STKc_CDK2_3 |
| cd07835 | 92-298 | STKc_CDK1_CdkB_like |
| cd14195 | 86-306 | STKc_DAPK3 |
| cd14110 | 98-297 | STKc_obscurin_rpt2 |
| cd14101 | 92-355 | STKc_PIM2 |
| cd14102 | 92-353 | STKc_PIM3 |
| cd14061 | 97-294 | STKc_MLK |
| cd06607 | 98-287 | STKc_TAO |
| cd14100 | 152-297 | STKc_PIM1 |
| cd05041 | 98-294 | PTKc_Fes_like |
| cd13982 | 96-354 | STKc_IRE1 |
| cd07878 | 90-308 | STKc_p38beta |
| cd07845 | 91-333 | STKc_CDK10 |
| cd14039 | 98-294 | STKc_IKK_alpha |
| cd07880 | 90-307 | STKc_p38gamma |
| cd14066 | 98-295 | STKc_IRAK |
| cd06617 | 90-294 | PKc_MKK3_6 |
| cd07877 | 90-294 | STKc_p38alpha |
| cd14064 | 98-294 | PKc_TNNI3K |
| cd13974 | 175-334 | STKc_SHIK |
| cd14059 | 167-294 | STKc_MAP3K12_13 |
| cd07861 | 91-298 | STKc_CDK1_euk |
| cd07865 | 73-287 | STKc_CDK9 |
| cd14147 | 96-316 | STKc_MLK3 |
| cd06633 | 98-295 | STKc_TAO3 |
| cd14145 | 85-316 | STKc_MLK1 |
| cd13986 | 92-294 | STKc_16 |
| cd07871 | 88-300 | STKc_PCTAIRE3 |
| cd07843 | 90-306 | STKc_CDC2L1 |
| cd14136 | 92-309 | STKc_SRPK |
| cd14038 | 98-294 | STKc_IKK_beta |
| cd05072 | 86-294 | PTKc_Lyn |
| cd14027 | 101-294 | STKc_RIP1 |
| cd14060 | 99-294 | STKc_MLTK |
| cd07856 | 90-308 | STKc_Sty1_Hog1 |
| cd14148 | 97-316 | STKc_MLK2 |
| cd14222 | 98-297 | STKc_LIMK2 |
| cd14012 | 156-320 | PK_eIF2AK_GCN2_rpt1 |
| cd13995 | 98-312 | STKc_MAP3K8 |
| cd14026 | 95-294 | STKc_RIP2 |
| cd07879 | 90-307 | STKc_p38delta |
| cd14664 | 98-294 | STK_BAK1_like |
| cd14134 | 69-294 | PKc_CLK |
| cd07837 | 90-298 | STKc_CdkB_plant |
| cd14017 | 92-293 | STKc_TTBK |
| cd07854 | 163-294 | STKc_MAPK4_6 |
| cd07850 | 92-308 | STKc_JNK |
| cd14146 | 97-316 | STKc_MLK4 |
| smart00109 | 1261-1307 | C1 |
| cd14037 | 94-329 | STKc_NAK_like |
| cd05084 | 98-294 | PTKc_Fes |
| cd07859 | 92-308 | STKc_TDY_MAPK |
| cd07853 | 98-308 | STKc_NLK |
| cd14155 | 98-288 | PKc_TESK |
| cd14133 | 92-308 | PKc_DYRK_like |
| cd07857 | 92-295 | STKc_MPK1 |
| cd14203 | 96-294 | PTKc_Src_Fyn_like |
| cd05067 | 90-294 | PTKc_Lck_Blk |
| cd05038 | 95-288 | PTKc_Jak_rpt2 |
| smart00133 | 357-417 | S_TK_X |
| cl11395 | 357-417 | Pkinase_C superfamily |
| cd06635 | 95-358 | STKc_TAO1 |
| cd14023 | 252-354 | PK_TRB1 |
| cd07862 | 90-308 | STKc_CDK6 |
| cd05082 | 87-294 | PTKc_Csk |
| cd06634 | 95-295 | STKc_TAO2 |
| cd05039 | 87-287 | PTKc_Csk_like |
| cd05032 | 90-294 | PTKc_InsR_like |
| cd05085 | 96-294 | PTKc_Fer |
| cd14022 | 193-354 | PK_TRB2 |
| cd14229 | 92-299 | STKc_HIPK3 |
| cd07872 | 88-300 | STKc_PCTAIRE2 |
| cd07864 | 92-297 | STKc_CDK12 |
| cd05059 | 95-294 | PTKc_Tec_like |
| cd14000 | 97-294 | STKc_LRRK |
| cd07839 | 92-295 | STKc_CDK5 |
| cd13976 | 252-354 | PK_TRB |
| cd05081 | 95-288 | PTKc_Jak3_rpt2 |
| cd07875 | 92-378 | STKc_JNK1 |
| cd07836 | 152-290 | STKc_Pho85 |
| cd14041 | 92-294 | STKc_TLK2 |
| cd05114 | 95-294 | PTKc_Tec_Rlk |
| cd05047 | 97-306 | PTKc_Tie |
| cd07873 | 90-300 | STKc_PCTAIRE1 |
| cd14040 | 90-294 | STKc_TLK1 |
| cd01243 | 1154-1230 | PH_MRCK |
| cd05070 | 86-330 | PTKc_Fyn |
| cd14158 | 98-294 | STKc_IRAK4 |
| cd13975 | 197-290 | PKc_Dusty |
| cd07874 | 92-317 | STKc_JNK3 |
| cd14024 | 160-353 | PK_TRB3 |
| cd07869 | 88-294 | STKc_PFTAIRE1 |
| cd14112 | 152-294 | STKc_Unc-89_rpt2 |
| cd07863 | 92-308 | STKc_CDK4 |
| cd14159 | 98-303 | STKc_IRAK1 |
| cd14049 | 91-288 | STKc_EIF2AK1_HRI |
| cd13981 | 92-224 | STKc_Bub1_BubR1 |
| cd05113 | 87-294 | PTKc_Btk_Bmx |
| cd14068 | 97-290 | STKc_LRRK2 |
| cd13968 | 98-234 | PKc_like |
| cd07858 | 92-294 | STKc_TEY_MAPK |
| cd05055 | 96-308 | PTKc_PDGFR |
| cd05097 | 98-234 | PTKc_DDR_like |
| cd07870 | 152-294 | STKc_PFTAIRE2 |
| cd07844 | 162-290 | STKc_PCTAIRE_like |
| cd05112 | 95-294 | PTKc_Itk |
| cd14224 | 92-290 | PKc_DYRK2_3 |
| cd07876 | 159-308 | STKc_JNK2 |
| cd05058 | 96-297 | PTKc_Met_Ron |
| cd05089 | 90-306 | PTKc_Tie1 |
| cd08227 | 93-294 | PK_STRAD_alpha |
| cd14227 | 92-295 | STKc_HIPK2 |
| cd05066 | 96-295 | PTKc_EphR_A |
| cd05069 | 98-294 | PTKc_Yes |
| cd14135 | 92-290 | STKc_PRP4 |
| cd14150 | 94-294 | STKc_A-Raf |
| cd14228 | 92-295 | STKc_HIPK1 |
| cd13983 | 137-294 | STKc_WNK |
| cd14055 | 96-288 | STKc_TGFbR2_like |
| cd05073 | 96-294 | PTKc_Hck |
| cd07842 | 92-288 | STKc_CDK8_like |
| cd05060 | 98-294 | PTKc_Syk_like |
| cd14215 | 90-294 | PKc_CLK2 |
| cd14062 | 197-294 | STKc_Raf |
| cd05083 | 96-294 | PTKc_Chk |
| cd14156 | 98-288 | PKc_LIMK_like_unk |
| cd05033 | 94-295 | PTKc_EphR |
| cd14210 | 92-290 | PKc_DYRK |
| cd05051 | 94-235 | PTKc_DDR |
| cd05095 | 98-234 | PTKc_DDR2 |
| cd14063 | 91-294 | PK_KSR |
| cd05036 | 95-294 | PTKc_ALK_LTK |
| cd05044 | 96-298 | PTKc_c-ros |
| cd14149 | 201-294 | STKc_C-Raf |
| cd14211 | 92-295 | STKc_HIPK |
| cd05034 | 96-287 | PTKc_Src_like |
| cd13977 | 164-305 | STKc_PDIK1L |
| cd13998 | 97-287 | STKc_TGFbR-like |
| cd05071 | 98-294 | PTKc_Src |
| cd14151 | 153-294 | STKc_B-Raf |
| cd05148 | 90-294 | PTKc_Srm_Brk |
| cd14011 | 139-356 | PK_SCY1_like |
| cd05074 | 96-294 | PTKc_Tyro3 |
| cd05049 | 87-298 | PTKc_Trk |
| cd05088 | 97-306 | PTKc_Tie2 |
| cd14031 | 98-357 | STKc_WNK3 |
| cd05101 | 96-294 | PTKc_FGFR2 |
| cd05052 | 98-306 | PTKc_Abl |
| cd14144 | 165-287 | STKc_BMPR1 |
| cd14018 | 180-295 | STKc_PINK1 |
| cd05080 | 160-288 | PTKc_Tyk2_rpt2 |
| cd05096 | 98-234 | PTKc_DDR1 |
| cd14213 | 92-294 | PKc_CLK1_4 |
| cd05079 | 95-298 | PTKc_Jak1_rpt2 |
| cd14138 | 89-224 | PTKc_Wee1a |
| cd14013 | 197-234 | STKc_SNT7_plant |
| cd00821 | 1153-1235 | PH |
| smart00220 | 92-354 | S_TKc |
| pfam01576 | 443-1124 | Myosin_tail_1 |
| PTZ00263 | 88-413 | PTZ00263 |
| pfam00069 | 92-354 | Pkinase |
| PTZ00426 | 86-390 | PTZ00426 |
| COG0515 | 91-428 | SPS1 |
| PHA03390 | 101-356 | pk1 |
| COG1196 | 436-1101 | Smc |
| TIGR02168 | 430-1126 | SMC_prok_B |
| COG1196 | 458-1126 | Smc |
| COG1196 | 430-1098 | Smc |
| PLN00034 | 90-353 | PLN00034 |
| TIGR02168 | 437-1126 | SMC_prok_B |
| smart00221 | 96-319 | STYKc |
| pfam07714 | 96-295 | Pkinase_Tyr |
| COG1196 | 433-1154 | Smc |
| smart00219 | 96-319 | TyrKc |
| COG0419 | 429-1041 | SbcC |
| COG1196 | 536-1127 | Smc |
| PTZ00267 | 119-298 | PTZ00267 |
| TIGR02169 | 440-1119 | SMC_prok_A |
| TIGR04523 | 434-1124 | Mplasa_alph_rch |
| PTZ00266 | 86-295 | PTZ00266 |
| TIGR02169 | 461-1126 | SMC_prok_A |
| PRK13184 | 92-324 | pknD |
| pfam02463 | 429-1091 | SMC_N |
| pfam02463 | 429-1126 | SMC_N |
| COG0419 | 641-1127 | SbcC |
| TIGR04523 | 439-1008 | Mplasa_alph_rch |
| TIGR02168 | 433-1013 | SMC_prok_B |
| TIGR02168 | 516-1127 | SMC_prok_B |
| TIGR00618 | 434-1124 | sbcc |
| pfam02463 | 463-1193 | SMC_N |
| PRK03918 | 464-1041 | PRK03918 |
| PRK03918 | 419-963 | PRK03918 |
| COG1196 | 723-1104 | Smc |
| pfam02463 | 437-1123 | SMC_N |
| COG1196 | 435-989 | Smc |
| pfam02463 | 440-1104 | SMC_N |
| pfam12128 | 481-1127 | DUF3584 |
| PTZ00283 | 88-294 | PTZ00283 |
| TIGR02168 | 476-1126 | SMC_prok_B |
| pfam01576 | 438-934 | Myosin_tail_1 |
| pfam05622 | 440-1026 | HOOK |
| pfam01576 | 609-1124 | Myosin_tail_1 |
| TIGR00606 | 447-1124 | rad50 |
| TIGR02169 | 423-803 | SMC_prok_A |
| pfam05483 | 463-1028 | SCP-1 |
| COG4717 | 438-1019 | YhaN |
| COG1196 | 429-743 | Smc |
| pfam05483 | 412-1080 | SCP-1 |
| TIGR02168 | 485-862 | SMC_prok_B |
| COG0419 | 662-1126 | SbcC |
| PTZ00121 | 426-1106 | PTZ00121 |
| PHA03207 | 92-295 | PHA03207 |
| TIGR02168 | 841-1132 | SMC_prok_B |
| PTZ00036 | 66-307 | PTZ00036 |
| PRK02224 | 441-1009 | PRK02224 |
| TIGR02169 | 429-1023 | SMC_prok_A |
| PTZ00121 | 435-1145 | PTZ00121 |
| TIGR00606 | 437-1136 | rad50 |
| pfam12128 | 452-1099 | DUF3584 |
| pfam01576 | 465-922 | Myosin_tail_1 |
| PTZ00121 | 437-1066 | PTZ00121 |
| TIGR02168 | 435-742 | SMC_prok_B |
| TIGR04523 | 598-1126 | Mplasa_alph_rch |
| TIGR02169 | 429-1087 | SMC_prok_A |
| TIGR04523 | 429-851 | Mplasa_alph_rch |
| pfam05483 | 479-1097 | SCP-1 |
| PTZ00121 | 429-1011 | PTZ00121 |
| PLN00009 | 90-306 | PLN00009 |
| pfam05557 | 669-1133 | MAD |
| COG1196 | 846-1127 | Smc |
| pfam10174 | 430-1079 | Cast |
| pfam01576 | 437-713 | Myosin_tail_1 |
| PTZ00024 | 96-306 | PTZ00024 |
| TIGR02169 | 667-1019 | SMC_prok_A |
| COG3096 | 484-1135 | MukB |
| pfam05557 | 429-933 | MAD |
| pfam02463 | 720-1099 | SMC_N |
| PHA03210 | 163-291 | PHA03210 |
| pfam05483 | 566-1126 | SCP-1 |
| pfam07888 | 728-1098 | CALCOCO1 |
| TIGR02169 | 747-1127 | SMC_prok_A |
| PRK01156 | 514-1089 | PRK01156 |
| pfam05483 | 444-908 | SCP-1 |
| PRK02224 | 524-1077 | PRK02224 |
| COG0419 | 428-793 | SbcC |
| pfam10174 | 454-1120 | Cast |
| PRK01156 | 437-902 | PRK01156 |
| pfam07111 | 547-1091 | HCR |
| PRK01156 | 437-1007 | PRK01156 |
| TIGR00618 | 434-1009 | sbcc |
| PHA03212 | 198-301 | PHA03212 |
| TIGR01612 | 471-1121 | 235kDa-fam |
| COG4372 | 764-964 | COG4372 |
| pfam10174 | 433-1126 | Cast |
| pfam02463 | 613-1144 | SMC_N |
| pfam07888 | 484-803 | CALCOCO1 |
| COG4372 | 441-634 | COG4372 |
| TIGR03903 | 114-265 | TOMM_kin_cyc |
| pfam09726 | 764-1042 | Macoilin |
| pfam13514 | 454-1125 | AAA_27 |
| pfam05701 | 836-1121 | WEMBL |
| pfam12128 | 439-968 | DUF3584 |
| pfam07111 | 441-1032 | HCR |
| pfam01576 | 818-1125 | Myosin_tail_1 |
| COG4942 | 758-973 | EnvC |
| pfam09726 | 461-717 | Macoilin |
| PRK04863 | 484-913 | mukB |
| pfam04111 | 429-547 | APG6 |
| pfam04111 | 855-1007 | APG6 |
| pfam04111 | 791-924 | APG6 |
| COG4942 | 765-1051 | EnvC |
| PHA03211 | 201-289 | PHA03211 |
| TIGR02169 | 440-685 | SMC_prok_A |
| PHA03209 | 176-288 | PHA03209 |
| pfam07888 | 643-1022 | CALCOCO1 |
| TIGR02169 | 877-1131 | SMC_prok_A |
| COG5281 | 429-637 | COG5281 |
| pfam05557 | 806-1096 | MAD |
| TIGR00606 | 418-792 | rad50 |
| PRK04863 | 833-1127 | mukB |
| PRK01156 | 586-1125 | PRK01156 |
| COG4717 | 477-1159 | YhaN |
| pfam09726 | 841-1097 | Macoilin |
| pfam02463 | 423-832 | SMC_N |
| COG4942 | 471-759 | EnvC |
| TIGR04523 | 429-855 | Mplasa_alph_rch |
| COG4372 | 907-1129 | COG4372 |
| COG4942 | 934-1133 | EnvC |
| pfam07888 | 439-722 | CALCOCO1 |
| TIGR01843 | 822-985 | type_I_hlyD |
| COG4942 | 548-803 | EnvC |
| COG1340 | 814-1079 | COG1340 |
| COG3883 | 715-935 | CwlO1 |
| COG4942 | 734-956 | EnvC |
| TIGR00618 | 430-753 | sbcc |
| pfam05622 | 627-1119 | HOOK |
| TIGR03319 | 849-1016 | RNase_Y |
| pfam13514 | 431-1007 | AAA_27 |
| TIGR04211 | 895-1005 | SH3_and_anchor |
| TIGR02302 | 590-867 | aProt_lowcomp |
| TIGR03185 | 772-1112 | DNA_S_dndD |
| COG0466 | 513-738 | Lon |
| TIGR03007 | 820-1028 | pepcterm_ChnLen |
| COG4942 | 827-1081 | EnvC |
| TIGR03185 | 435-747 | DNA_S_dndD |
| COG4477 | 671-1097 | EzrA |
| COG1340 | 687-966 | COG1340 |
| PRK04863 | 478-912 | mukB |
| pfam09726 | 950-1126 | Macoilin |
| COG4372 | 784-1035 | COG4372 |
| pfam04111 | 738-867 | APG6 |
| pfam07111 | 814-1133 | HCR |
| PRK02224 | 704-1122 | PRK02224 |
| COG4372 | 727-977 | COG4372 |
| pfam13514 | 462-1132 | AAA_27 |
| PRK04863 | 604-1006 | mukB |
| TIGR04211 | 535-633 | SH3_and_anchor |
| PTZ00121 | 435-845 | PTZ00121 |
| TIGR03007 | 852-1078 | pepcterm_ChnLen |
| COG5185 | 753-1110 | HEC1 |
| COG5283 | 817-1195 | COG5283 |
| pfam13514 | 701-1018 | AAA_27 |
| PRK02224 | 711-1127 | PRK02224 |
| TIGR03319 | 464-635 | RNase_Y |
| COG5281 | 855-1126 | COG5281 |
| pfam12128 | 429-778 | DUF3584 |
| PRK04863 | 436-1132 | mukB |
| TIGR03794 | 846-1042 | NHLM_micro_HlyD |
| COG5281 | 535-935 | COG5281 |
| TIGR03794 | 980-1182 | NHLM_micro_HlyD |
| COG4913 | 765-1005 | COG4913 |
| TIGR04211 | 492-606 | SH3_and_anchor |
| pfam13514 | 834-1125 | AAA_27 |
| PTZ00121 | 430-752 | PTZ00121 |
| COG4477 | 443-738 | EzrA |
| TIGR03007 | 482-799 | pepcterm_ChnLen |
| pfam05622 | 834-1125 | HOOK |
| pfam12128 | 787-1122 | DUF3584 |
| COG5022 | 436-975 | COG5022 |
| COG0497 | 895-1127 | RecN |
| COG2433 | 890-1075 | COG2433 |
| pfam09726 | 549-782 | Macoilin |
| TIGR04211 | 841-931 | SH3_and_anchor |
| pfam09726 | 441-632 | Macoilin |
| COG5185 | 458-777 | HEC1 |
| COG2433 | 450-597 | COG2433 |
| COG2433 | 440-575 | COG2433 |
| pfam05701 | 653-1040 | WEMBL |
| COG3064 | 797-966 | TolA |
| COG5192 | 775-1154 | BMS1 |
| COG4942 | 439-634 | EnvC |
| COG5022 | 420-1007 | COG5022 |
| TIGR01612 | 672-1100 | 235kDa-fam |
| COG5271 | 596-1053 | MDN1 |
| TIGR03319 | 747-931 | RNase_Y |
| COG1340 | 484-744 | COG1340 |
| COG2433 | 839-966 | COG2433 |
| COG1579 | 723-910 | COG1579 |
| COG3206 | 435-611 | GumC |
| COG4717 | 533-1136 | YhaN |
| COG4372 | 435-613 | COG4372 |
| TIGR04211 | 951-1044 | SH3_and_anchor |
| PRK04863 | 443-1077 | mukB |
| TIGR02680 | 833-1005 | TIGR02680 |
| COG3883 | 504-749 | CwlO1 |
| pfam04111 | 1019-1132 | APG6 |
| COG3206 | 839-1045 | GumC |
| TIGR00634 | 880-1104 | recN |
| TIGR01069 | 820-941 | mutS2 |
| COG3883 | 421-594 | CwlO1 |
Ontology Information
| HPRD ID | 6339 |
|---|---|
| Molecular Class | Serine/threonine kinase |
| Molecular Function | Transcription cofactor activity (GO:0003712) |
| Biological Process | CAMP-mediated signaling (GO:0019933) |
Drug Information
No matching records could be found.