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General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| RPL19 | 6143 | ribosomal protein L19 | 17 | FLJ27452, MGC71997, DKFZp779D216, L19 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 18266979 | 2008 | Cell line : CCD 18Co, ATCC CRL-1459; CCD-112CoN, ATCC CRL-1541; DLD-1, ATCC CCL-221; SW480, ATCC CCL-228; HT-29, ATCC HTB-38; LoVo, ATCC CCL-229; Caco-2, ATCC HTB-37; HCT 116, ATCC CCL-247; COLO 205, ATCC CCL-222; SW 1116, ATCC CCL-233; and T84, ATCC CCL-248 Source : Cathay General Hospital and Taipei Veterans General Hospital, Taipei, Taiwan. Sample Type : CRC tumor and normal tissues No. of Sample : 109 Stage : - | Oligonucleotide microarray hybridization | Up-regulation | - | Faecal RPL19 expression is associated with advanced tumour stages and addictive to serum CEA in predicting prognosis of CRC patients. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | L ribosomal proteins |
| Description | Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L19E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008] | Chromosome | 17 |
| Location | 17q12 |
| Start | 37356536 |
| End | 37360980 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 4445 |
| OMIM ID | 180466 |
| HGNC ID | HGNC:10312 |
| Unigene ID | Hs.381061 |
| Ensembl ID | ENSG00000108298 |
| PharmGKB ID | PA34681 |
mRNA Information
| mRNA ID | ?NM_000981.3 |
|---|---|
| Exon | join(1..67,931..1037,2035..2157,2707..2827,3795..3905, 4243..4445) | mRNA Sequence | Download Select all |
| Length | 748 |
Protein Information
| Protein ID | NP_000972.1 |
|---|---|
| Protein Name | ribosomal protein L19 |
| Molecular Wt. (Da) | 14656 |
| Protein Sequence | Download Select all |
| Length | 196 |
| Uniprot ID | O95388 |
| Ensembl Protein ID | ENSP00000220856 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 13 |
| T | Phosphorylation | 187 |
| S | Phosphorylation | 12 |
| K | Acetylation | 80 |
| K | Acetylation | 180 |
| S | Phosphorylation | 37 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Ribosome | hsa03010 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd01417 | 4-167 | Ribosomal_L19e_E |
| cl00232 | 4-167 | Ribosomal_L19e superfamily |
| PTZ00097 | 3-177 | PTZ00097 |
| pfam01280 | 2-149 | Ribosomal_L19e |
| cd00481 | 4-148 | Ribosomal_L19e |
| COG2147 | 1-149 | RPL19A |
| PRK08570 | 1-149 | rpl19e |
| cd01418 | 4-142 | Ribosomal_L19e_A |
| PTZ00436 | 1-183 | PTZ00436 |
| smart00435 | 138-196 | TOPEUc |
Ontology Information
| HPRD ID | 5079 |
|---|---|
| Molecular Class | Ribosomal subunit |
| Molecular Function | Molecular function unknown (GO:0005554) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.