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General Information
- Evidence
- Gene
- mRNA
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- Protein
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- Enzyme
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Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 23826192 | 2013 | Cell line : - Source : Cathay General Hospital or Taipei Veterans General Hospital. Sample Type : Solid fecal samples No. of Sample : 80 sporadic CRC patients (42 at stage II and 38 at stage III). Stage : TNM stage II , III | Lentivirus-based RNA Interference (RNAi) and Overexpression of RPS27L,Apoptosis Assay,c-H2AX Foci Formation Assay. | Up-regulation | - | Elevated RPS27L may improve the prognoses of certain CRC patients by enhancing the DNA repair capacity of their colonic cells. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | S ribosomal proteins |
| Description | This gene encodes a protein sharing 96% amino acid similarity with ribosomal protein S27, which suggests the encoded protein may be a component of the 40S ribosomal subunit. [provided by RefSeq, Jul 2008] | Chromosome | 15 |
| Location | 15q21.3 |
| Start | 63445539 |
| End | 63449741 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 4203 |
| OMIM ID | 612055 |
| HGNC ID | HGNC:18476 |
| Unigene ID | Hs.108957 |
| Ensembl ID | ENSG00000185088 |
| PharmGKB ID | PA38546 |
Protein Information
| Protein ID | NP_057004.1 |
|---|---|
| Protein Name | ribosomal protein S27-like |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 84 |
| Uniprot ID | Q9H3R2 |
| Ensembl Protein ID | ENSP00000485028 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 78 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Ribosome | hsa03010 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| PLN00209 | Jun-82 | PLN00209 |
| cl00897 | Jun-82 | Ribosomal_S27e superfamily |
| PTZ00083 | Jun-82 | PTZ00083 |
| pfam01667 | 28-82 | Ribosomal_S27e |
| COG2051 | 26-82 | RPS27A |
| PRK00415 | 24-73 | rps27e |
Ontology Information
| HPRD ID | 5714 |
|---|---|
| Molecular Class | Unclassified |
| Molecular Function | Hormone activity (GO:0005179) |
| Biological Process | Biological_process unknown (GO:0000004) |
Drug Information
No matching records could be found.