Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| RPS6KB1 | 6198 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 17 | S6K1, p70(S6K)-alpha, PS6K |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 21035469 | 2011 | Cell line : - Source : Utah, the Northern California Kaiser Permanente Medical Care Program (KPMCP), and the Twin Cities Metropolitan area of Minnesota (colon cancer study only). Sample Type : Population-based case-control studies No. of Sample : Colon 1574 cases, 1940 controls and rectal 791 cases, 999 controls Stage : - | CpG island methylator phenotype, MSI analysis | Polymorhpism | - | Observed genetic variation in RPS6KA1, RPS6KA2, and PRS6KB2 were associated with risk of developing colon cancer while only genetic variation in RPS6KA2 was associated with altering risk of rectal cancer. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013] | Chromosome | 17 |
| Location | 17q23.1 |
| Start | 57970407 |
| End | 58027787 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 57381 |
| OMIM ID | 608938 |
| HGNC ID | HGNC:10436 |
| Unigene ID | Hs.463642 |
| Ensembl ID | ENSG00000108443 |
| PharmGKB ID | PA34851 |
mRNA Information
| mRNA ID | ?NM_001272042.1 |
|---|---|
| Exon | join(1..280,751..879,17517..17566,19639..19759, 21590..21658,33390..33537,37072..37129,38577..38677, 41125..41215,41389..41479,42148..42255,43170..43232, 43419..43496,47791..47898,52361..52473,53506..57381) | mRNA Sequence | Download Select all |
| Length | 5497 |
Protein Information
| Protein ID | NP_001258971.1 |
|---|---|
| Protein Name | ribosomal protein S6 kinase, 70kDa, polypeptide 1 |
| Molecular Wt. (Da) | 53324 |
| Protein Sequence | Download Select all |
| Length | 525 |
| Uniprot ID | O95497 |
| Ensembl Protein ID | ENSP00000356905 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| T | Phosphorylation | 390 |
| S | Phosphorylation | 427 |
| S | Phosphorylation | 441 |
| T | Phosphorylation | 470 |
| S | Phosphorylation | 394 |
| T | Phosphorylation | 252 |
| T | Phosphorylation | 412 |
| S | Phosphorylation | 394 |
| S | Phosphorylation | 434 |
| T | Phosphorylation | 390 |
| T | Phosphorylation | 390 |
| T | Phosphorylation | 390 |
| T | Phosphorylation | 412 |
| T | Phosphorylation | 444 |
| S | Phosphorylation | 447 |
| K | Acetylation | 304 |
| S | Phosphorylation | 452 |
| T | Phosphorylation | 412 |
| S | Phosphorylation | 398 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 207 | AKT1 | 1261 | NP_005154.2 | in vitro | 11438723 |
| 998 | CDC42 | 309 | NP_001782.1 | in vitro | 11438723 |
| 1460 | CSNK2B | 278 | NP_001311.3 | in vitro;in vivo;yeast 2-hybrid | 16895915 |
| 1975 | EIF4B | 4892 | NP_001408.2 | in vitro;in vivo | 16763566 |
| 1978 | EIF4EBP1 | 3746 | NP_004086.1 | in vivo | 11438723 |
| 4137 | MAPT | 1142 | NP_001116538.1 | in vitro | 16364302 |
| 4686 | NCBP1 | 2717 | NP_002477.1 | in vivo | 10973943 |
| 5515 | PPP2CA | 8912 | NP_002706.1 | in vitro;in vivo | 11 438 723 161 097 100 000 000 000 000 000 |
| 5594 | MAPK1 | 1496 | NP_002736.3 | in vitro;in vivo | 1 205 462 411 279 230 |
| 5879 | RAC1 | 3627 | NP_061485.1 | in vitro | 11438723 |
| 6194 | RPS6 | 1592 | NP_001001.2 | in vitro | 1 143 872 316 810 320 |
| 6794 | STK11 | 3740 | NP_000446.1 | in vitro;in vivo | 1 129 752 011 853 550 |
| 7514 | XPO1 | 3975 | NP_003391.1 | in vivo | 16895915 |
| 9618 | TRAF4 | 3915 | NP_004286.2 | in vivo | 12801526 |
| 29904 | EEF2K | 7369 | NP_037434.1 | in vitro;in vivo | 11 500 364 147 095 500 000 000 000 000 000 |
| 84271 | POLDIP3 | 17875 | NP_115687.2 | in vitro;in vivo | 15341740 |
| 84687 | PPP1R9B | 4506 | NP_115984.3 | in vitro;in vivo;yeast 2-hybrid | 9653190 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Acute myeloid leukemia | hsa05221 |
| AMPK signaling pathway | hsa04152 |
| Choline metabolism in cancer | hsa05231 |
| ErbB signaling pathway | hsa04012 |
| Fc gamma R-mediated phagocytosis | hsa04666 |
| HIF-1 signaling pathway | hsa04066 |
| Insulin resistance | hsa04931 |
| Insulin signaling pathway | hsa04910 |
| Longevity regulating pathway - mammal | hsa04211 |
| Longevity regulating pathway - multiple species | hsa04213 |
| mTOR signaling pathway | hsa04150 |
| PI3K-Akt signaling pathway | hsa04151 |
| Proteoglycans in cancer | hsa05205 |
| TGF-beta signaling pathway | hsa04350 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd05584 | 94-416 | STKc_p70S6K |
| cl21453 | 94-416 | PKc_like superfamily |
| cd05582 | 95-414 | STKc_RSK_N |
| cd05123 | 97-352 | STKc_AGC |
| cd05614 | 91-416 | STKc_MSK2_N |
| cd05575 | 95-414 | STKc_SGK |
| cd05570 | 95-414 | STKc_PKC |
| cd05571 | 95-416 | STKc_PKB |
| cd05583 | 96-355 | STKc_MSK_N |
| cd05580 | 91-383 | STKc_PKA_like |
| cd05585 | 96-413 | STKc_YPK1_like |
| cd05613 | 91-371 | STKc_MSK1_N |
| cd05595 | 95-415 | STKc_PKB_beta |
| cd05589 | 91-416 | STKc_PKN |
| cd05592 | 95-416 | STKc_nPKC_theta_like |
| cd05604 | 94-416 | STKc_SGK3 |
| cd05603 | 95-414 | STKc_SGK2 |
| cd05602 | 87-416 | STKc_SGK1 |
| cd05587 | 94-414 | STKc_cPKC |
| cd05590 | 95-418 | STKc_nPKC_eta |
| cd05573 | 91-413 | STKc_ROCK_NDR_like |
| cd05586 | 97-413 | STKc_Sck1_like |
| cd05591 | 95-414 | STKc_nPKC_epsilon |
| cd05599 | 91-413 | STKc_NDR_like |
| cd05574 | 91-378 | STKc_phototropin_like |
| cd05594 | 76-417 | STKc_PKB_alpha |
| cd05579 | 99-357 | STKc_MAST_like |
| cd05593 | 91-415 | STKc_PKB_gamma |
| cd05616 | 91-414 | STKc_cPKC_beta |
| cd05612 | 91-384 | STKc_PRKX_like |
| cd05598 | 91-413 | STKc_LATS |
| cd05588 | 95-414 | STKc_aPKC |
| cd14007 | 91-353 | STKc_Aurora |
| cd14209 | 91-383 | STKc_PKA |
| cd05572 | 97-359 | STKc_cGK |
| cd05615 | 84-416 | STKc_cPKC_alpha |
| cd05619 | 85-416 | STKc_nPKC_theta |
| cd05620 | 95-416 | STKc_nPKC_delta |
| cd05581 | 91-352 | STKc_PDK1 |
| cd05117 | 91-351 | STKc_CAMK |
| cd05618 | 70-421 | STKc_aPKC_iota |
| cd14003 | 91-351 | STKc_AMPK-like |
| cd05578 | 91-352 | STKc_Yank1 |
| cd05601 | 91-414 | STKc_CRIK |
| cd05600 | 85-413 | STKc_Sid2p_like |
| cd05617 | 91-421 | STKc_aPKC_zeta |
| cd05629 | 89-413 | STKc_NDR_like_fungal |
| cd05611 | 94-358 | STKc_Rim15_like |
| cd05597 | 91-413 | STKc_DMPK_like |
| cd05605 | 91-371 | STKc_GRK4_like |
| cd05577 | 97-371 | STKc_GRK |
| cd05610 | 89-389 | STKc_MASTL |
| cd05624 | 91-419 | STKc_MRCK_beta |
| cd05596 | 85-414 | STKc_ROCK |
| cd05630 | 91-371 | STKc_GRK6 |
| cd08215 | 91-352 | STKc_Nek |
| cd05627 | 91-413 | STKc_NDR2 |
| cd05606 | 96-371 | STKc_beta_ARK |
| cd05626 | 91-399 | STKc_LATS2 |
| cd05609 | 91-357 | STKc_MAST |
| cd05122 | 90-352 | PKc_STE |
| cd05623 | 85-419 | STKc_MRCK_alpha |
| cd05631 | 91-371 | STKc_GRK4 |
| cd06606 | 95-352 | STKc_MAPKKK |
| cd05632 | 91-371 | STKc_GRK5 |
| cd05625 | 91-405 | STKc_LATS1 |
| cd05628 | 89-413 | STKc_NDR1 |
| cd05608 | 91-371 | STKc_GRK1 |
| cd14014 | 91-346 | STKc_PknB_like |
| cd14663 | 91-336 | STKc_SnRK3 |
| cd14099 | 95-352 | STKc_PLK |
| cd00180 | 97-350 | PKc |
| cd05607 | 91-371 | STKc_GRK7 |
| cd05621 | 85-413 | STKc_ROCK2 |
| cd05633 | 91-371 | STKc_GRK3 |
| cd14223 | 91-371 | STKc_GRK2 |
| cd14116 | 89-351 | STKc_Aurora-A |
| cd14009 | 97-351 | STKc_ATG1_ULK_like |
| cd14098 | 91-338 | STKc_Rad53_Cds1 |
| cd05622 | 85-413 | STKc_ROCK1 |
| cd14008 | 97-352 | STKc_LKB1_CaMKK |
| cd14081 | 91-352 | STKc_BRSK1_2 |
| cd14084 | 83-328 | STKc_Chk2 |
| cd14095 | 90-350 | STKc_DCKL |
| cd14006 | 97-338 | STKc_MLCK-like |
| cd14117 | 91-368 | STKc_Aurora-B_like |
| cd08217 | 91-335 | STKc_Nek2 |
| cd14002 | 89-351 | STKc_STK36 |
| cd14166 | 89-335 | STKc_CaMKI_gamma |
| cd14074 | 91-351 | STKc_SNRK |
| cd14075 | 95-336 | STKc_NIM1 |
| cd14167 | 89-335 | STKc_CaMKI_alpha |
| cd14086 | 91-354 | STKc_CaMKII |
| cd14186 | 89-351 | STKc_PLK4 |
| cd14096 | 91-351 | STKc_RCK1-like |
| cd06623 | 91-356 | PKc_MAPKK_plant_like |
| cd14120 | 97-351 | STKc_ULK1_2-like |
| cd14073 | 91-335 | STKc_NUAK |
| cd14080 | 91-352 | STKc_TSSK-like |
| cd14072 | 91-335 | STKc_MARK |
| cd14083 | 91-335 | STKc_CaMKI |
| cd14069 | 91-352 | STKc_Chk1 |
| cd05118 | 91-352 | STKc_CMGC |
| cd08219 | 91-338 | STKc_Nek3 |
| cd14106 | 101-338 | STKc_DRAK |
| cd14087 | 91-339 | STKc_PSKH1 |
| cd14091 | 91-354 | STKc_RSK_C |
| cd14185 | 91-351 | STKc_DCKL3 |
| cd06632 | 95-351 | STKc_MEKK1_plant |
| cd06627 | 97-352 | STKc_Cdc7_like |
| cd06614 | 91-352 | STKc_PAK |
| cd14184 | 89-351 | STKc_DCKL2 |
| cd14079 | 95-352 | STKc_AMPK_alpha |
| cd14189 | 95-352 | STKc_PLK3 |
| cd06609 | 91-353 | STKc_MST3_like |
| cd13999 | 97-335 | STKc_MAP3K-like |
| cd14103 | 97-338 | STKc_MLCK |
| cd14097 | 95-338 | STKc_STK33 |
| cd08529 | 91-335 | STKc_FA2-like |
| cd06605 | 91-352 | PKc_MAPKK |
| cd14187 | 95-335 | STKc_PLK1 |
| cd14114 | 91-338 | STKc_Twitchin_like |
| cd08530 | 91-337 | STKc_CNK2-like |
| cd07829 | 91-352 | STKc_CDK_like |
| cd14121 | 97-351 | STKc_ULK3 |
| cd06625 | 95-352 | STKc_MEKK3_like |
| cd14161 | 91-335 | STKc_NUAK2 |
| cd14093 | 108-352 | STKc_PhKG |
| cd14192 | 96-338 | STKc_MLCK3 |
| cd14119 | 97-352 | STKc_LKB1 |
| cd14078 | 91-336 | STKc_MELK |
| cd06612 | 83-352 | STKc_MST1_2 |
| cd14092 | 97-353 | STKc_MSK_C |
| cd14202 | 91-352 | STKc_ULK1 |
| cd14168 | 89-335 | STKc_CaMKI_delta |
| cd14169 | 99-336 | STKc_CaMKI_beta |
| cd14085 | 91-338 | STKc_CaMKIV |
| cd14188 | 95-352 | STKc_PLK2 |
| cd14090 | 96-351 | STKc_Mnk |
| cd07833 | 91-352 | STKc_CDKL |
| cd14191 | 97-336 | STKc_MLCK1 |
| cd14010 | 91-351 | STKc_ULK4 |
| cd08225 | 91-335 | STKc_Nek5 |
| cd08218 | 94-335 | STKc_Nek1 |
| cd14094 | 89-353 | STKc_CASK |
| cd14076 | 93-336 | STKc_Kin4 |
| cd14196 | 91-336 | STKc_DAPK2 |
| cd14105 | 91-336 | STKc_DAPK |
| cd14089 | 95-350 | STKc_MAPKAPK |
| cd14070 | 95-335 | STKc_HUNK |
| cd14201 | 91-352 | STKc_ULK2 |
| cd14165 | 91-352 | STKc_TSSK1_2-like |
| cd14077 | 91-351 | STKc_Kin1_2 |
| cd05576 | 95-352 | STKc_RPK118_like |
| cd08528 | 91-335 | STKc_Nek10 |
| cd06608 | 91-351 | STKc_myosinIII_N_like |
| cd13994 | 97-336 | STKc_HAL4_like |
| cd06613 | 91-352 | STKc_MAP4K3_like |
| cd14174 | 96-353 | STKc_Mnk1 |
| cd14179 | 95-336 | STKc_MSK1_C |
| cd14005 | 90-352 | STKc_PIM |
| cd14162 | 91-328 | STKc_TSSK4-like |
| cd14183 | 89-351 | STKc_DCKL1 |
| cd14118 | 97-336 | STKc_CAMKK |
| cd06629 | 97-351 | STKc_Bck1_like |
| cd06611 | 89-352 | STKc_SLK_like |
| cd07830 | 91-352 | STKc_MAK_like |
| cd14195 | 101-336 | STKc_DAPK3 |
| cd06644 | 89-356 | STKc_STK10 |
| cd14181 | 101-352 | STKc_PhKG2 |
| cd14071 | 91-337 | STKc_SIK |
| cd06626 | 95-351 | STKc_MEKK4 |
| cd14082 | 96-339 | STKc_PKD |
| cd14173 | 96-351 | STKc_Mnk2 |
| cd06647 | 97-353 | STKc_PAK_I |
| cd14107 | 91-352 | STKc_obscurin_rpt1 |
| cd14190 | 96-352 | STKc_MLCK2 |
| cd14193 | 96-338 | STKc_MLCK4 |
| cd14004 | 91-335 | STKc_PASK |
| cd14662 | 91-351 | STKc_SnRK2 |
| cd14194 | 101-336 | STKc_DAPK1 |
| cd06631 | 96-351 | STKc_YSK4 |
| cd14198 | 87-335 | STKc_DRAK2 |
| cd06628 | 95-351 | STKc_Byr2_like |
| cd06643 | 86-351 | STKc_SLK |
| cd07840 | 91-352 | STKc_CDK9_like |
| cd07838 | 91-352 | STKc_CDK4_6_like |
| cd13996 | 91-335 | STKc_EIF2AK |
| cd08223 | 91-335 | STKc_Nek4 |
| cd14176 | 91-354 | STKc_RSK2_C |
| cd08222 | 91-351 | STKc_Nek11 |
| cd14137 | 91-352 | STKc_GSK3 |
| cd14180 | 89-336 | STKc_MSK2_C |
| cd06630 | 96-353 | STKc_MEKK1 |
| cd07832 | 91-352 | STKc_CCRK |
| cd13985 | 94-335 | STKc_GAK_like |
| cd06655 | 97-353 | STKc_PAK2 |
| cd14175 | 141-351 | STKc_RSK1_C |
| cd07841 | 91-353 | STKc_CDK7 |
| cd14197 | 101-338 | STKc_DRAK1 |
| cd06656 | 97-353 | STKc_PAK3 |
| cd14665 | 91-336 | STKc_SnRK2-3 |
| cd06917 | 91-342 | STKc_NAK1_like |
| cd07835 | 91-352 | STKc_CDK1_CdkB_like |
| cd14088 | 91-338 | STKc_CaMK_like |
| cd07831 | 95-352 | STKc_MOK |
| cd13993 | 91-335 | STKc_Pat1_like |
| cd08224 | 91-335 | STKc_Nek6_7 |
| cd07852 | 91-369 | STKc_MAPK15-like |
| cd06648 | 143-353 | STKc_PAK_II |
| cd08220 | 91-340 | STKc_Nek8 |
| cd06610 | 145-352 | STKc_OSR1_SPAK |
| cd06654 | 97-353 | STKc_PAK1 |
| cd00192 | 95-335 | PTKc |
| cd14113 | 101-338 | STKc_Trio_C |
| cd13997 | 91-335 | PKc_Wee1_like |
| cd14178 | 141-360 | STKc_RSK3_C |
| cd07834 | 91-378 | STKc_MAPK |
| cd14172 | 95-336 | STKc_MAPKAPK3 |
| cd14171 | 95-351 | STKc_MAPKAPK5 |
| cd14164 | 91-339 | STKc_TSSK6-like |
| cd14177 | 89-338 | STKc_RSK4_C |
| cd06620 | 85-335 | PKc_Byr1_like |
| cd06659 | 97-366 | STKc_PAK6 |
| cd07860 | 91-352 | STKc_CDK2_3 |
| cd07836 | 91-352 | STKc_Pho85 |
| cd14046 | 91-338 | STKc_EIF2AK4_GCN2_rpt2 |
| cd08221 | 94-335 | STKc_Nek9 |
| cd14200 | 91-351 | STKc_CaMKK1 |
| cd14182 | 89-354 | STKc_PhKG1 |
| cd06624 | 96-340 | STKc_ASK |
| cd13990 | 93-351 | STKc_TLK |
| cd06653 | 88-328 | STKc_MEKK3_like_u1 |
| cd14199 | 91-351 | STKc_CaMKK2 |
| cd07848 | 91-314 | STKc_CDKL5 |
| cd14131 | 91-351 | PKc_Mps1 |
| cd06638 | 89-335 | STKc_myosinIIIA_N |
| cd08228 | 91-328 | STKc_Nek6 |
| cd14115 | 101-351 | STKc_Kalirin_C |
| cd07843 | 89-352 | STKc_CDC2L1 |
| cd06640 | 89-319 | STKc_MST4 |
| cd06657 | 99-352 | STKc_PAK4 |
| cd07846 | 89-314 | STKc_CDKL2_3 |
| cd14104 | 97-353 | STKc_Titin |
| cd06652 | 88-328 | STKc_MEKK2 |
| cd14170 | 95-379 | STKc_MAPKAPK2 |
| cd14052 | 91-285 | PTKc_Wee1_fungi |
| cd06621 | 91-354 | PKc_Pek1_like |
| cd06658 | 99-353 | STKc_PAK5 |
| cd06639 | 91-316 | STKc_myosinIIIB_N |
| cd14133 | 91-352 | PKc_DYRK_like |
| cd06622 | 92-351 | PKc_PBS2_like |
| cd06642 | 89-325 | STKc_STK25 |
| cd14050 | 89-280 | PKc_Myt1 |
| cd14109 | 143-352 | PK_Unc-89_rpt1 |
| cd14019 | 91-352 | STKc_Cdc7 |
| cd06641 | 89-332 | STKc_MST3 |
| cd07851 | 88-378 | STKc_p38 |
| cd06645 | 81-351 | STKc_MAP4K3 |
| cd13987 | 97-335 | STKc_SBK1 |
| cd13979 | 93-297 | STKc_Mos |
| cd14038 | 97-293 | STKc_IKK_beta |
| cd14111 | 97-335 | STKc_SPEG_rpt2 |
| cd06615 | 91-359 | PKc_MEK |
| cd14000 | 96-335 | STKc_LRRK |
| cd07861 | 91-352 | STKc_CDK1_euk |
| cd13989 | 97-293 | STKc_IKK |
| cd06651 | 95-351 | STKc_MEKK3 |
| cd14163 | 91-352 | STKc_TSSK3-like |
| cd07855 | 91-370 | STKc_ERK5 |
| cd06636 | 91-351 | STKc_MAP4K4_6_N |
| cd07880 | 88-390 | STKc_p38gamma |
| cd08229 | 94-328 | STKc_Nek7 |
| cd14132 | 88-352 | STKc_CK2_alpha |
| cd06646 | 91-292 | STKc_MAP4K5 |
| cd07871 | 89-352 | STKc_PCTAIRE3 |
| cd07877 | 88-390 | STKc_p38alpha |
| cd07873 | 89-352 | STKc_PCTAIRE1 |
| cd06617 | 91-352 | PKc_MKK3_6 |
| cd06650 | 85-320 | PKc_MEK1 |
| cd07837 | 89-352 | STKc_CdkB_plant |
| cd07849 | 91-351 | STKc_ERK1_2_like |
| cd14066 | 97-346 | STKc_IRAK |
| cd13978 | 97-296 | STKc_RIP |
| cd14059 | 97-293 | STKc_MAP3K12_13 |
| cd14108 | 101-352 | STKc_SPEG_rpt1 |
| cd07839 | 91-352 | STKc_CDK5 |
| cd07844 | 91-352 | STKc_PCTAIRE_like |
| cd14101 | 96-335 | STKc_PIM2 |
| cd06637 | 91-353 | STKc_TNIK |
| cd13982 | 152-352 | STKc_IRE1 |
| cd07845 | 91-353 | STKc_CDK10 |
| cd14061 | 96-295 | STKc_MLK |
| cd14039 | 97-293 | STKc_IKK_alpha |
| smart00133 | 353-415 | S_TK_X |
| cl11395 | 353-415 | Pkinase_C superfamily |
| cd13988 | 97-309 | STKc_TBK1 |
| cd14016 | 91-314 | STKc_CK1 |
| cd07878 | 88-352 | STKc_p38beta |
| cd07866 | 91-352 | STKc_BUR1 |
| cd14210 | 91-331 | PKc_DYRK |
| cd13986 | 91-335 | STKc_16 |
| cd05038 | 93-288 | PTKc_Jak_rpt2 |
| cd07847 | 89-295 | STKc_CDKL1_4 |
| cd07879 | 88-352 | STKc_p38delta |
| cd14067 | 97-307 | STKc_LRRK1 |
| cd07863 | 91-352 | STKc_CDK4 |
| cd07857 | 91-386 | STKc_MPK1 |
| cd14048 | 91-335 | STKc_EIF2AK3_PERK |
| cd07865 | 91-352 | STKc_CDK9 |
| cd14145 | 93-313 | STKc_MLK1 |
| cd14147 | 91-313 | STKc_MLK3 |
| cd14110 | 103-335 | STKc_obscurin_rpt2 |
| cd07862 | 91-352 | STKc_CDK6 |
| cd13995 | 99-338 | STKc_MAP3K8 |
| cd14036 | 95-336 | STKc_GAK |
| cd07869 | 87-295 | STKc_PFTAIRE1 |
| cd14027 | 97-335 | STKc_RIP1 |
| cd07864 | 91-338 | STKc_CDK12 |
| cd07872 | 89-355 | STKc_PCTAIRE2 |
| cd05055 | 92-326 | PTKc_PDGFR |
| cd07870 | 94-352 | STKc_PFTAIRE2 |
| cd07856 | 90-297 | STKc_Sty1_Hog1 |
| cd14012 | 147-351 | PK_eIF2AK_GCN2_rpt1 |
| cd05079 | 94-288 | PTKc_Jak1_rpt2 |
| cd07859 | 91-376 | STKc_TDY_MAPK |
| cd14058 | 97-293 | STKc_TAK1 |
| cd14224 | 91-297 | PKc_DYRK2_3 |
| cd07854 | 94-352 | STKc_MAPK4_6 |
| cd14102 | 96-335 | STKc_PIM3 |
| cd13991 | 97-294 | STKc_NIK |
| cd07842 | 91-300 | STKc_CDK8_like |
| cd14049 | 91-335 | STKc_EIF2AK1_HRI |
| cd14022 | 192-352 | PK_TRB2 |
| cd14065 | 97-291 | PKc_LIMK_like |
| cd14047 | 91-287 | STKc_EIF2AK2_PKR |
| cd05045 | 93-295 | PTKc_RET |
| cd06649 | 85-300 | PKc_MEK2 |
| cd14100 | 96-335 | STKc_PIM1 |
| cd14146 | 96-313 | STKc_MLK4 |
| cd05056 | 86-316 | PTKc_FAK |
| cd07850 | 94-368 | STKc_JNK |
| cd14041 | 91-352 | STKc_TLK2 |
| cd06619 | 94-293 | PKc_MKK5 |
| cd14225 | 91-314 | PKc_DYRK4 |
| cd14064 | 97-293 | PKc_TNNI3K |
| cd05081 | 94-288 | PTKc_Jak3_rpt2 |
| cd14040 | 89-336 | STKc_TLK1 |
| cd14148 | 96-293 | STKc_MLK2 |
| cd14112 | 114-335 | STKc_Unc-89_rpt2 |
| cd14037 | 95-329 | STKc_NAK_like |
| cd13983 | 96-293 | STKc_WNK |
| cd14226 | 91-314 | PKc_DYRK1 |
| cd14158 | 95-298 | STKc_IRAK4 |
| cd14205 | 93-288 | PTKc_Jak2_rpt2 |
| cd07876 | 91-307 | STKc_JNK2 |
| cd06618 | 94-354 | PKc_MKK7 |
| cd14024 | 157-351 | PK_TRB3 |
| cd14156 | 97-291 | PKc_LIMK_like_unk |
| cd05059 | 86-306 | PTKc_Tec_like |
| cd06607 | 91-351 | STKc_TAO |
| cd05068 | 70-318 | PTKc_Frk_like |
| cd14011 | 199-354 | PK_SCY1_like |
| cd06633 | 73-297 | STKc_TAO3 |
| cd06635 | 73-297 | STKc_TAO1 |
| cd14025 | 95-302 | STKc_RIP4_like |
| cd05074 | 86-324 | PTKc_Tyro3 |
| cd05084 | 97-314 | PTKc_Fes |
| cd05039 | 86-286 | PTKc_Csk_like |
| cd05108 | 91-335 | PTKc_EGFR |
| cd05072 | 85-335 | PTKc_Lyn |
| cd05032 | 86-336 | PTKc_InsR_like |
| cd05080 | 91-299 | PTKc_Tyk2_rpt2 |
| cd05116 | 97-337 | PTKc_Syk |
| cd05082 | 91-335 | PTKc_Csk |
| cd06616 | 97-297 | PKc_MKK4 |
| cd14023 | 192-352 | PK_TRB1 |
| cd05148 | 87-318 | PTKc_Srm_Brk |
| cd14068 | 96-335 | STKc_LRRK2 |
| cd05101 | 52-295 | PTKc_FGFR2 |
| cd14060 | 98-295 | STKc_MLTK |
| cd14221 | 97-287 | STKc_LIMK1 |
| cd05098 | 97-295 | PTKc_FGFR1 |
| cd14211 | 91-314 | STKc_HIPK |
| cd05053 | 92-319 | PTKc_FGFR |
| cd14056 | 96-287 | STKc_TGFbR_I |
| cd05063 | 85-293 | PTKc_EphR_A2 |
| cd05113 | 86-319 | PTKc_Btk_Bmx |
| cd13976 | 201-352 | PK_TRB |
| cd14026 | 94-293 | STKc_RIP2 |
| cd07858 | 97-295 | STKc_TEY_MAPK |
| cd05115 | 97-318 | PTKc_Zap-70 |
| cd05041 | 97-335 | PTKc_Fes_like |
| cd05109 | 94-326 | PTKc_HER2 |
| cd14154 | 97-280 | STKc_LIMK |
| cd05067 | 89-335 | PTKc_Lck_Blk |
| cd05049 | 86-336 | PTKc_Trk |
| cd07853 | 91-353 | STKc_NLK |
| cd06634 | 73-297 | STKc_TAO2 |
| cd14159 | 97-307 | STKc_IRAK1 |
| cd05060 | 97-326 | PTKc_Syk_like |
| cd14150 | 92-302 | STKc_A-Raf |
| cd05099 | 97-295 | PTKc_FGFR4 |
| cd05034 | 95-335 | PTKc_Src_like |
| cd05047 | 96-335 | PTKc_Tie |
| cd05058 | 95-293 | PTKc_Met_Ron |
| cd14222 | 97-287 | STKc_LIMK2 |
| cd05057 | 91-335 | PTKc_EGFR_like |
| cd05090 | 97-314 | PTKc_Ror1 |
| cd07875 | 132-377 | STKc_JNK1 |
| cd14134 | 91-386 | PKc_CLK |
| cd14151 | 97-326 | STKc_B-Raf |
| cd05085 | 96-335 | PTKc_Fer |
| cd05100 | 71-295 | PTKc_FGFR3 |
| cd07874 | 132-307 | STKc_JNK3 |
| cd05054 | 95-319 | PTKc_VEGFR |
| cd05065 | 86-337 | PTKc_EphR_B |
| cd14062 | 97-306 | STKc_Raf |
| cd05048 | 92-316 | PTKc_Ror |
| cd05044 | 95-336 | PTKc_c-ros |
| cd14136 | 95-289 | STKc_SRPK |
| cd14229 | 91-295 | STKc_HIPK3 |
| cd05066 | 86-293 | PTKc_EphR_A |
| cd05114 | 142-293 | PTKc_Tec_Rlk |
| cd14135 | 97-330 | STKc_PRP4 |
| cd05040 | 97-335 | PTKc_Ack_like |
| cd13974 | 185-339 | STKc_SHIK |
| cd05083 | 93-314 | PTKc_Chk |
| cd05112 | 86-298 | PTKc_Itk |
| cd14212 | 91-320 | PKc_YAK1 |
| cd13968 | 97-238 | PKc_like |
| cd08216 | 92-362 | PK_STRAD |
| cd14149 | 93-302 | STKc_C-Raf |
| cd05052 | 97-295 | PTKc_Abl |
| cd14664 | 97-303 | STK_BAK1_like |
| cd13998 | 96-286 | STKc_TGFbR-like |
| cd14017 | 91-327 | STKc_TTBK |
| cd05093 | 93-336 | PTKc_TrkB |
| cd05043 | 86-293 | PTK_Ryk |
| cd05070 | 85-305 | PTKc_Fyn |
| cd14227 | 91-305 | STKc_HIPK2 |
| cd05088 | 96-335 | PTKc_Tie2 |
| cd14207 | 89-335 | PTKc_VEGFR1 |
| cd14228 | 91-305 | STKc_HIPK1 |
| cd14155 | 97-280 | PKc_TESK |
| cd07867 | 97-293 | STKc_CDC2L6 |
| cd05050 | 92-338 | PTKc_Musk |
| cd14203 | 97-316 | PTKc_Src_Fyn_like |
| cd05046 | 94-314 | PTK_CCK4 |
| cd05033 | 86-314 | PTKc_EphR |
| cd13981 | 97-289 | STKc_Bub1_BubR1 |
| cd05089 | 96-295 | PTKc_Tie1 |
| cd14018 | 194-338 | STKc_PINK1 |
| cd05105 | 187-326 | PTKc_PDGFR_alpha |
| cd05092 | 97-336 | PTKc_TrkA |
| cd05075 | 93-314 | PTKc_Axl |
| cd14054 | 96-288 | STKc_BMPR2_AMHR2 |
| cd05110 | 94-335 | PTKc_HER4 |
| cd13975 | 209-289 | PKc_Dusty |
| cd14214 | 89-306 | PKc_CLK3 |
| cd14031 | 141-336 | STKc_WNK3 |
| cd14020 | 97-338 | STKc_KIS |
| cd05071 | 85-335 | PTKc_Src |
| cd14032 | 141-352 | STKc_WNK2_like |
| cd05102 | 93-324 | PTKc_VEGFR3 |
| cd05073 | 85-302 | PTKc_Hck |
| cd07868 | 97-293 | STKc_CDK8 |
| cd14215 | 89-352 | PKc_CLK2 |
| cd05111 | 86-295 | PTK_HER3 |
| pfam00433 | 373-417 | Pkinase_C |
| cd05103 | 191-319 | PTKc_VEGFR2 |
| cd14063 | 201-297 | PK_KSR |
| cd13977 | 168-338 | STKc_PDIK1L |
| cd13992 | 130-308 | PK_GC |
| cd05069 | 85-326 | PTKc_Yes |
| cd14160 | 101-289 | PK_IRAK3 |
| cd05035 | 91-324 | PTKc_TAM |
| cd14142 | 93-286 | STKc_ACVR1_ALK1 |
| cd14152 | 92-331 | STKc_KSR1 |
| cd14033 | 143-294 | STKc_WNK4 |
| COG3642 | 156-239 | Bud32 |
| smart00220 | 91-352 | S_TKc |
| PTZ00263 | 91-411 | PTZ00263 |
| pfam00069 | 91-352 | Pkinase |
| PTZ00426 | 85-383 | PTZ00426 |
| COG0515 | 91-444 | SPS1 |
| smart00221 | 92-335 | STYKc |
| pfam07714 | 91-355 | Pkinase_Tyr |
| smart00219 | 92-335 | TyrKc |
| PTZ00267 | 114-335 | PTZ00267 |
| PHA03390 | 100-352 | pk1 |
| PTZ00283 | 78-336 | PTZ00283 |
| PTZ00024 | 97-338 | PTZ00024 |
| PLN00034 | 75-351 | PLN00034 |
| TIGR03903 | 116-334 | TOMM_kin_cyc |
| PTZ00266 | 91-338 | PTZ00266 |
| PLN00009 | 89-307 | PLN00009 |
| PHA03207 | 91-308 | PHA03207 |
| PTZ00036 | 36-307 | PTZ00036 |
| PHA03212 | 130-289 | PHA03212 |
| PHA03209 | 91-287 | PHA03209 |
| PRK13184 | 91-304 | pknD |
| PHA03210 | 205-313 | PHA03210 |
Ontology Information
| HPRD ID | 10349 |
|---|---|
| Molecular Class | Serine/threonine kinase |
| Molecular Function | Transcription regulator activity (GO:0030528) |
| Biological Process | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219) |
Drug Information
No matching records could be found.