Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| S100A10 | 6281 | S100 calcium binding protein A10 | 1 | P11, 42C, CLP11 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 23828264 | 2013 | Cell line : - Source : - Sample Type : - No. of Sample : 882 CRC patients Stage : - | Immunohistochemistry | Up-regulation | - | S100A10 as a prognostic marker and potential therapeutic target in colorectal cancer. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | S100 calcium binding proteins |
| Description | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in exocytosis and endocytosis. | Chromosome | 1 |
| Location | 1q21 |
| Start | 151982910 |
| End | 151994238 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 11329 |
| OMIM ID | 114085 |
| HGNC ID | HGNC:10487 |
| Unigene ID | Hs.143873 |
| Ensembl ID | ENSG00000197747 |
| PharmGKB ID | - |
mRNA Information
| mRNA ID | NM_002966.2 |
|---|---|
| Exon | join(1..487,7988..8140,10915..11329) | mRNA Sequence | Download Select all |
| Length | 1069 |
CDS Information
| Location | join(8009..8140,10915..11076) |
|---|---|
| CDS Sequence | Download Select all |
| CCDS ID | CCDS1008.1 |
Protein Information
| Protein ID | NP_002957.1 |
|---|---|
| Protein Name | S100 calcium binding protein A10 |
| Molecular Wt. (Da) | 11072 |
| Protein Sequence | Download Select all |
| Length | 97 |
| Uniprot ID | P07900 |
| Ensembl Protein ID | ENSP00000216281 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| Y | Phosphorylation | 25;- |
| K | Acetylation | 28 |
| K | Acetylation | 23 |
| K | Acetylation | 57 |
| K | Acetylation | 54 |
| K | Acetylation | 37 |
| S | Phosphorylation | 3 |
| T | Phosphorylation | 11 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 9869 | SETDB1 | 6828 | NP_001138887.1 | yeast 2-hybrid | 16169070 |
| 10980 | COPS6 | 16735 | NP_006824.2 | yeast 2-hybrid | 16169070 |
Pathway Information
No matching records could be found.
Structure Information
| PDB ID | 1A4P |
|---|---|
| Resolution | 2.25 |
| Method | X-RAY DIFFRACTION |
| Chains | A,B |
| Molecule | S100A10 |
| Model | View |
Domain Information
| ID | Location | Description |
|---|---|---|
| cd05024 | Mar-93 | S-100A10 |
| cl08302 | Mar-93 | EFh superfamily |
| cd05031 | Mar-93 | S-100A10_like |
| cd00213 | Mar-87 | S-100 |
| cd05025 | Mar-88 | S-100A1 |
| cd05026 | Jan-88 | S-100Z |
| cd05023 | Feb-87 | S-100A11 |
| cd05030 | Mar-85 | calgranulins |
| cd05027 | Mar-87 | S-100B |
| cd05022 | Mar-80 | S-100A13 |
| pfam01023 | May-45 | S_100 |
| cl19180 | May-45 | S_100 superfamily |
| cd05029 | Jan-85 | S-100A6 |
| cd00051 | 13-77 | EFh |
Ontology Information
| HPRD ID | 2535 |
|---|---|
| Molecular Class | Calcium binding protein |
| Molecular Function | Heat shock protein activity (GO:0003773) |
| Biological Process | Protein metabolism (GO:0019538) |
Drug Information
No matching records could be found.