Search results:
General Information
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 25007175 | 2014 | Cell line : - Source : - Sample Type : CRC Tumor and adjescent tissue No. of Sample : - Stage : - | - | Up-regulation | - | Significant up-regulation in tumors was found for S100A11, S100A7, LCE3D, S100A3 and S100A2 genes. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | S100 calcium binding proteins, "EF-hand domain containing" |
| Description | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities. [provided by RefSeq, Nov 2014] | Chromosome | 1 |
| Location | 1q21 |
| Start | 153430220 |
| End | 153436559 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 6340 |
| OMIM ID | 600353 |
| HGNC ID | HGNC:10497 |
| Unigene ID | Hs.112408 |
| Ensembl ID | ENSG00000143556 |
| PharmGKB ID | PA34909 |
mRNA Information
| mRNA ID | ?NM_002963.3 |
|---|---|
| Exon | join(1..54,1632..1789,2692..2918) | mRNA Sequence | Download Select all |
| Length | 450 |
Protein Information
| Protein ID | NP_002954.2 |
|---|---|
| Protein Name | S100 calcium binding protein A7 |
| Molecular Wt. (Da) | 11609 |
| Protein Sequence | Download Select all |
| Length | 101 |
| Uniprot ID | Q9UBB5 |
| Ensembl Protein ID | ENSP00000256429 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| C | Disulfide Bridge | 47;96 |
| Q | Transglutamination | 5 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00213 | Apr-90 | S-100 |
| cl08302 | Apr-90 | EFh superfamily |
| pfam01023 | Jul-44 | S_100 |
| cl19180 | Jul-44 | S_100 superfamily |
| cd05030 | Apr-90 | calgranulins |
| cd05023 | Apr-87 | S-100A11 |
| cd05022 | Apr-92 | S-100A13 |
Ontology Information
| HPRD ID | 5572 |
|---|---|
| Molecular Class | Calcium binding protein |
| Molecular Function | Protease inhibitor activity (GO:0030414) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.