Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| SAPCD2 | 89958 | suppressor APC domain containing 2 | 9 | p42.3 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 23576022 | 2013 | Cell line : - Source : - Sample Type : CRC tissue and blood sample No. of Sample : 212 CRC Stage : - | real time RT-PCR, Western Blotting, Immunohistochemistry, microarray | Up-regulation | - | p42.3 might play an important role in the progression of CRC, and it has a great value for assessing CRC patient prognosis after surgery. p42.3 was demonstrated to be over-expressed in colorectal cancer tissues compared with normal mucosa in the 14 tissue pairs (P = 0.011) and was significantly higher in patients with poor tumor differentiation (P = 0.045); patients positive for p42.3 expression had a poorer prognosis than those not expressing this protein (P = 0.033). |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | |
| Description | - | Chromosome | 9 |
| Location | 9q34.3 |
| Start | 137062124 |
| End | 137070576 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 8453 |
| OMIM ID | 612057 |
| HGNC ID | HGNC:28055 |
| Unigene ID | Hs.19322 |
| Ensembl ID | ENSG00000186193 |
| PharmGKB ID | - |
mRNA Information
| mRNA ID | XM_011519180.1 |
|---|---|
| Exon | join(36..687,784..873,4203..4315,4909..5055,5392..5499, 5598..5714,5790..8453) | mRNA Sequence | Download Select all |
| Length | 3865 |
CDS Information
| Location | join(117..687,4203..4315,4909..5055,5392..5499,5598..5714, 5790..5918) |
|---|---|
| CDS Sequence | Download Select all |
| CCDS ID | CCDS7027.2 |
Protein Information
| Protein ID | NP_848543.2 |
|---|---|
| Protein Name | suppressor APC domain containing 2 |
| Molecular Wt. (Da) | 42506 |
| Protein Sequence | Download Select all |
| Length | 394 |
| Uniprot ID | P02545 |
| Ensembl Protein ID | ENSP00000292304 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
No STRING Network could be found.
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam11414 | 224-306 | Suppressor_APC |
| cl12943 | 224-306 | Suppressor_APC superfamily |
| TIGR04523 | 336-375 | Mplasa_alph_rch |
Ontology Information
| HPRD ID | 1036 |
|---|---|
| Molecular Class | Unclassified |
| Molecular Function | Structural molecule activity (GO:0005198) |
| Biological Process | Cell growth and/or maintenance (GO:0008151) |
Drug Information
No matching records could be found.