Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| SCGN | 10590 | secretagogin, EF-hand calcium binding protein | 6 | SECRET, DJ501N12.8, SEGN, CALBL |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 16586428 | 2006 | Cell line : - Source : - Sample Type : - No. of Sample : - Stage : - | 2-DE, MS/MS, immunohistochemistry | Down-regulation | - | Findings might represent the basis for the clinical application of secretagogin as a biomarker for a distinct subgroup of colorectal cancers. Immunohistochemistry revealed absence of secretagogin-expressing cells in most of the colorectal cancer tissue specimens. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | EF-hand domain containing |
| Description | The encoded protein is a secreted calcium-binding protein which is found in the cytoplasm. It is related to calbindin D-28K and calretinin. This protein is thought to be involved in KCL-stimulated calcium flux and cell proliferation. | Chromosome | 6 |
| Location | 6p22.3-p22 |
| Start | 25652201 |
| End | 25701783 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 49583 |
| OMIM ID | 609202 |
| HGNC ID | HGNC:16941 |
| Unigene ID | Hs.116428 |
| Ensembl ID | ENSG00000079689 |
| PharmGKB ID | - |
mRNA Information
| mRNA ID | NM_006998.3 |
|---|---|
| Exon | join(1..285,1182..1252,9352..9444,12743..12832, 17311..17367,17799..17876,29751..29806,36972..37017, 37273..37332,38856..38924,49007..49583) | mRNA Sequence | Download Select all |
| Length | 1492 |
CDS Information
| Location | join(204..285,1182..1252,9352..9444,12743..12832, 17311..17367,17799..17876,29751..29806,36972..37017, 37273..37332,38856..38924,49007..49135) |
|---|---|
| CDS Sequence | Download Select all |
| CCDS ID | CCDS4561.1 |
Protein Information
| Protein ID | NP_008929.2 |
|---|---|
| Protein Name | secretagogin, EF-hand calcium binding protein |
| Molecular Wt. (Da) | 31909 |
| Protein Sequence | Download Select all |
| Length | 276 |
| Uniprot ID | P05556 |
| Ensembl Protein ID | ENSP00000303351 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00051 | 109-179 | EFh |
| cl08302 | 109-179 | EFh superfamily |
| pfam13405 | 109-137 | EF-hand_6 |
| cl23634 | 109-137 | EF-hand_6 superfamily |
| pfam13833 | 121-181 | EF-hand_8 |
| smart00054 | 109-137 | EFh |
| cl23347 | 109-137 | EFh superfamily |
| pfam13499 | 115-178 | EF-hand_7 |
| PTZ00184 | 15-178 | PTZ00184 |
Ontology Information
| HPRD ID | 1428 |
|---|---|
| Molecular Class | Calcium binding protein |
| Molecular Function | Receptor activity (GO:0004872) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.