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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
SCUBE2 57758 signal peptide, CUB domain, EGF-like 2  11Cegf1, Cegb1, FLJ16792 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
25672935   2015Cell line : RKO

Source : -

Sample Type : CRC tumor and normal tissue

No. of Sample : -

Stage : -

real time RT- PCR, western blotting and immunohistochemistry on a tissue microarrayDown-regulation-SCUBE2 plays an important role in suppressing CRC progression and prognosis.


Gene Details



NC_000011.9 (9041047..9113150, complement)

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Gene Type protein coding
Gene Family -
Description -  
Chromosome 11
Location 11p15.4
Start 9041047  
End 9113150  
Strand -  
Gene Sequence

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Length 72104  
OMIM ID 611747   
HGNC ID HGNC:30425   
Unigene ID Hs.523468   
Ensembl ID ENSG00000175356   
PharmGKB ID PA134908812   

mRNA Information


mRNA ID ?NM_001170690.1
Exon  
mRNA Sequence

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Length  



CDS Information


   
Location
CDS Sequence

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CCDS ID CCDS53599.1



Protein Information


      
Protein IDNP_001164161.1
Protein Namesignal peptide, CUB domain, EGF-like 2
Molecular Wt. (Da)0
Protein Sequence

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Length 999  
Uniprot IDP58397
Ensembl Protein ID ENSP00000344847  



Post-translational Modification Information (Source : HPRD)


No matching records could be found.

Enzyme Information


No matching records could be found.

PPi Information


No STRING Network could be found.

               
Interactant Gene ID (Source: HPRD) Gene Symbol HPRD ID Ref Seq ID Technique References
80274SCUBE118029NP_766638.2in vitro12270931   


Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
cd00041809-920  CUB
cl00049809-920  CUB superfamily
cd0005445-85  EGF_CA
cl2150445-85  EGF_CA superfamily
pfam00431809-918  CUB
smart00042818-918  CUB
pfam07699757-804  GCC2_GCC3
cl06646757-804  GCC2_GCC3 superfamily
pfam07699701-748  GCC2_GCC3
cl06646701-748  GCC2_GCC3 superfamily
pfam07699644-694  GCC2_GCC3
cl06646644-694  GCC2_GCC3 superfamily
pfam14670286-321  FXa_inhibition
cl21504286-321  EGF_CA superfamily
pfam14670407-442  FXa_inhibition
cl21504407-442  EGF_CA superfamily
cd01475312-361  vWA_Matrilin
cl00057312-361  vWFA superfamily
pfam1294749-84  EGF_3
pfam14670132-167  FXa_inhibition
cl21504132-167  EGF_CA superfamily
cd01475359-395  vWA_Matrilin
cl00057359-395  vWFA superfamily
pfam14670327-362  FXa_inhibition
cl21504327-362  EGF_CA superfamily
pfam14670217-252  FXa_inhibition
cl21504217-252  EGF_CA superfamily
pfam0764545-78  EGF_CA
smart0017945-85  EGF_CA
pfam1467095-126  FXa_inhibition
cl2150495-126  EGF_CA superfamily
cd01475401-440  vWA_Matrilin
cl00057401-440  vWFA superfamily
cd01475126-166  vWA_Matrilin
cl00057126-166  vWFA superfamily
pfam12662305-326  cEGF
pfam12662109-131  cEGF
smart00179403-433  EGF_CA
pfam1266268-89  cEGF
pfam14670177-213  FXa_inhibition
cl21504177-213  EGF_CA superfamily
cd00054403-436  EGF_CA
pfam12947407-434  EGF_3
smart00179128-158  EGF_CA
smart0017986-126  EGF_CA
smart00179364-394  EGF_CA
cl21504364-394  EGF_CA superfamily
cd0147580-123  vWA_Matrilin
cl0005780-123  vWFA superfamily
cd00054364-395  EGF_CA
pfam12662344-367  cEGF
smart00179323-363  EGF_CA


Ontology Information


   
HPRD ID10817
Molecular ClassSecreted polypeptide
Molecular FunctionCytoskeletal protein binding (GO:0008092)
Biological ProcessSpindle assembly (GO:0007051); Chromosome segregation (GO:0007059)  



SNP Information


View SNP Geneview Report   

Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO