Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| SLC25A4 | 291 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4  | 4 | T1  |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 21625861    | 2012 | Cell line : LoVo, SW480, HT29 and Caco 2 Source : - Sample Type : - No. of Sample : - Stage : - | real time RT-PCR | Unknown | - | - |
Gene Details

| Gene Type | protein coding |
|---|---|
| Gene Family | Solute carriers |
| Description | This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Mutations in this gene have been shown to result in autosomal dominant progressive external opthalmoplegia and familial hypertrophic cardiomyopathy. [provided by RefSeq, Jun 2013]   | Chromosome | 4 |
| Location | 4q35 |
| Start | 186064417   |
| End | 186071538   |
| Strand | +   |
| Gene Sequence |    Download   Select all |
| Length | 7122   |
| OMIM ID | 103220    |
| HGNC ID | HGNC:10990    |
| Unigene ID | Hs.246506    |
| Ensembl ID | ENSG00000151729    |
| PharmGKB ID | PA35866    |
mRNA Information
| mRNA ID | NM_001151.3 |
|---|---|
| Exon | join(1..221,1502..1988,2497..2637,3552..7122)   | mRNA Sequence |    Download   Select all |
| Length | 4420   |
CDS Information
| Location | 111..1007 |
|---|---|
| CDS Sequence |    Download   Select all |
| CCDS ID | CCDS34114.1 |    
Protein Information
| Protein ID | NP_001142.2 |
|---|---|
| Protein Name | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 |
| Molecular Wt. (Da) | 32933 |
| Protein Sequence |    Download   Select all |
| Length | 298   |
| Uniprot ID | P33993 |    
| Ensembl Protein ID | ENSP00000307288   |    
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| K | Acetylation | 272 |
| K | Acetylation | 96 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING)      View   
No matching records from HPRD source could be found.
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Calcium signaling pathway |    hsa04020 |    
| cGMP-PKG signaling pathway |    hsa04022 |    
| HTLV-I infection |    hsa05166 |    
| Huntington's disease |    hsa05016 |    
| Parkinson's disease |    hsa05012 |    
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam00153 | 7-101  | Mito_carr |
| cl02813 | 7-101  | Mito_carr superfamily |
| pfam00153 | 110-206  | Mito_carr |
| cl02813 | 110-206  | Mito_carr superfamily |
| pfam00153 | 222-297  | Mito_carr |
| cl02813 | 222-297  | Mito_carr superfamily |
| PTZ00169 | 7-298  | PTZ00169 |
| PTZ00168 | 116-238  | PTZ00168 |
Ontology Information
| HPRD ID | 406 |    
|---|---|
| Molecular Class | Transport/cargo protein |
| Molecular Function | Receptor activity (GO:0004872) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165)   |
Drug Information
| Uniprot ID | DrugBank ID | Name | Type |
|---|---|---|---|
| P12235 | DB00171 | Adenosine triphosphate | SmallMoleculeDrug |
| P12235 | DB00720 | Clodronate | SmallMoleculeDrug |
External Links
| ArrayExpress | GO |    
|---|---|
| ICGC | GO |    
| Cancer3D | GO |    
| COSMIC | GO |    
| NCG | GO |    
| TSGene | GO |    
| Tumor Gene Family of Databases | GO |    
| CCDB | GO |    
| G2SBC | GO |    
| Osteosarcoma Database | GO |    
| RCDB | GO |    
