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General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| SLURP1 | 57152 | secreted LY6/PLAUR domain containing 1 | 8 | ARS, ANUP, MDM, ArsB, LY6LS |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 18764860 | 2008 | Cell line : HT 29 Source : - Sample Type : - No. of Sample : - Stage : - | RT-PCR, Western blotting and immunocytochemistry | Up-regulation | - | SLURP-1 participates in the regulation of gut immune functions and motility, as well as possibly playing a role in colon carcinogenesis/cancer progression. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | The protein encoded by this gene is a member of the Ly6/uPAR family but lacks a GPI-anchoring signal sequence. It is thought that this secreted protein contains antitumor activity. Mutations in this gene have been associated with Mal de Meleda, a rare autosomal recessive skin disorder. This gene maps to the same chromosomal region as several members of the Ly6/uPAR family of glycoprotein receptors. [provided by RefSeq, Jul 2008] | Chromosome | 8 |
| Location | 8q24.3 |
| Start | 143822362 |
| End | 143823829 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 1468 |
| OMIM ID | 606119 |
| HGNC ID | HGNC:18746 |
| Unigene ID | Hs.103505 |
| Ensembl ID | ENSG00000126233 |
| PharmGKB ID | PA134936818 |
Protein Information
| Protein ID | NP_065160.1 |
|---|---|
| Protein Name | secreted LY6/PLAUR domain containing 1 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 103 |
| Uniprot ID | Q3L8U1 |
| Ensembl Protein ID | ENSP00000381522 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00117 | 23-101 | LU |
| cl10471 | 23-101 | LU superfamily |
| pfam00021 | 25-100 | UPAR_LY6 |
| smart00134 | 23-100 | LU |
Ontology Information
| HPRD ID | 13265 |
|---|---|
| Molecular Class | Unclassified |
| Molecular Function | Calcium ion binding (GO:0005509) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.