Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| SNTB1 | 6641 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 8 | A1B; SNT2; BSYN2; 59-DAP; DAPA1B; SNT2B1; TIP-43 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 21531130 | 2011 | Cell line : - Source : Japanees patients Sample Type : CRC tumor and normal tissue No. of Sample : 113 primary CRC Stage : TNM Stage I-III | Peptide Nucleic Acid (PNA)-clamp real-timeRT-PCR TaqMan assay, Gene expression profiles | Up-regulation | - | - |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Pleckstrin homology (PH) domain containing |
| Description | Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes. [provided by RefSeq, Jul 2008] | Chromosome | 8 |
| Location | 8q23-q24 |
| Start | 120535745 |
| End | 120812069 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 276325 |
| OMIM ID | 600026 |
| HGNC ID | HGNC:11168 |
| Unigene ID | Hs.46701 |
| Ensembl ID | ENSG00000172164 |
| PharmGKB ID | - |
mRNA Information
| mRNA ID | NM_021021.3 |
|---|---|
| Exon | join(1..797,118162..118378,179419..179626,236845..236984, 263112..263308,270070..270260,273101..276325) | mRNA Sequence | Download Select all |
| Length | 4975 |
CDS Information
| Location | join(227..797,118162..118378,179419..179626, 236845..236984,263112..263308,270070..270260, 273101..273193) |
|---|---|
| CDS Sequence | Download Select all |
| CCDS ID | CCDS6334.1 |
Protein Information
| Protein ID | NP_066301.1 |
|---|---|
| Protein Name | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) |
| Molecular Wt. (Da) | 57930 |
| Protein Sequence | Download Select all |
| Length | 538 |
| Uniprot ID | Q9UI36 |
| Ensembl Protein ID | ENSP00000482245 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 389;- |
| S | Phosphorylation | 219;- |
| S | Phosphorylation | 87 |
| S | Phosphorylation | 205 |
| T | Phosphorylation | 214 |
| S | Phosphorylation | 397 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 1756 | DMD | 2303 | NP_003997.1 | in vitro;in vivo | 78 441 508 576 247 |
| 7402 | UTRN | 547 | NP_009055.2 | in vivo | 8576247 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd01258 | 242-299 | PHsplit_syntrophin |
| cl17171 | 242-299 | PH-like superfamily |
| cd00992 | 111-192 | PDZ_signaling |
| cl00117 | 111-192 | PDZ superfamily |
| cd00821 | 327-428 | PH |
| cl17171 | 327-428 | PH-like superfamily |
| pfam00595 | 113-192 | PDZ |
| smart00228 | 115-193 | PDZ |
| pfam00169 | 323-433 | PH |
| smart00233 | 323-433 | PH |
| cd00136 | 121-192 | PDZ |
| cd00988 | 120-192 | PDZ_CTP_protease |
| smart00233 | 231-295 | PH |
| pfam13180 | 121-192 | PDZ_2 |
| COG0793 | 119-191 | CtpA |
Ontology Information
| HPRD ID | 545 |
|---|---|
| Molecular Class | Adapter molecule |
| Molecular Function | Cytoskeletal protein binding (GO:0008092) |
| Biological Process | Cell growth and/or maintenance (GO:0008151) |
Drug Information
No matching records could be found.