Search results:


General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
SON 6651 SON DNA binding protein  21SON3; BASS1; DBP-5; NREBP; C21orf50 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
20089989   2010Cell line : -

Source : VU University Medical Center, Amsterdam, The Netherlands.

Sample Type : CRC tumor and normal tissue

No. of Sample : -

Stage : -

Biochemical isolation to nano-LC-MS/MS analysisUnknown--


Gene Details



Chromosome: 21; NC_000021.8 (34915350..34949812)

View Larger Image
   
Gene Type protein coding
Gene Family G patch domain containing
Description The protein encoded by this gene binds to a specific DNA sequence upstream of the upstream regulatory sequence of the core promoter and second enhancer of human hepatitis B virus (HBV). Through this binding, it represses HBV core promoter activity, transcription of HBV genes, and production of HBV virions. The protein shows sequence similarities with other DNA-binding structural proteins such as gallin, oncoproteins of the MYC family, and the oncoprotein MOS. It may also be involved in protecting cells from apoptosis and in pre-mRNA splicing. Several transcript variants encoding different isoforms have been described for this gene, but the full-length nature of only two of them has been determined. [provided by RefSeq, Jul 2008]  
Chromosome 21
Location 21q22.11
Start 33543038  
End 33577514  
Strand +  
Gene Sequence

   Download   Select all

Length 34477  
OMIM ID 182465   
HGNC ID HGNC:11183   
Unigene ID Hs.517262    
Ensembl ID ENSG00000159140   
PharmGKB ID PA36020   

mRNA Information


mRNA ID NM_138927.2
Exon join(1..132,3176..3342,6439..12354,14119..14279, 16193..16339,16550..16738,24120..24230,25934..26050, 30271..30418,32559..32630,32741..32856,33328..34477)  
mRNA Sequence

   Download   Select all

Length 8440  



CDS Information


   
Location join(56..132,3176..3342,6439..12354,14119..14279, 16193..16339,16550..16738,24120..24230,25934..26050, 30271..30418,32559..32630,32741..32856,33328..33387)
CDS Sequence

   Download   Select all

CCDS ID CCDS13629.1



Protein Information


      
Protein IDNP_001278340.1
Protein NameSON DNA binding protein
Molecular Wt. (Da)228077
Protein Sequence

   Download   Select all

Length 2108  
Uniprot IDP53355
Ensembl Protein ID ENSP00000350785  



Post-translational Modification Information (Source : HPRD)


Residue Type site
SPhosphorylation1651
SPhosphorylation1697
SPhosphorylation1766
SPhosphorylation1769
SPhosphorylation2013
SPhosphorylation910
SPhosphorylation1651
SPhosphorylation1697
SPhosphorylation1766
SPhosphorylation1769
SPhosphorylation2013
SPhosphorylation910
SPhosphorylation154
SPhosphorylation154
SPhosphorylation283
SPhosphorylation283
SPhosphorylation1697;-
SPhosphorylation1378;-
SPhosphorylation1697;-
SPhosphorylation1697;-
SPhosphorylation1697;-
SPhosphorylation1657;-
SPhosphorylation2013;-
SPhosphorylation1694;-
SPhosphorylation2013;-
SPhosphorylation2013;-
SPhosphorylation2013;-
SPhosphorylation1973;-
SPhosphorylation94;-
SPhosphorylation94;-
SPhosphorylation94;-
SPhosphorylation94;-
SPhosphorylation94;-
SPhosphorylation94;-
SPhosphorylation1780;-
SPhosphorylation1782;-
SPhosphorylation1450;-
SPhosphorylation1463;-
SPhosphorylation1461;-
SPhosphorylation1447;-
SPhosphorylation1780;-
SPhosphorylation1782;-
SPhosphorylation1769;-
SPhosphorylation1780;-
SPhosphorylation1782;-
SPhosphorylation1766;-
SPhosphorylation1769;-
SPhosphorylation1780;-
SPhosphorylation1782;-
SPhosphorylation1766;-
SPhosphorylation1729;-
SPhosphorylation1740;-
SPhosphorylation1742;-
SPhosphorylation1726;-
SPhosphorylation1784;-
SPhosphorylation1783;-
SPhosphorylation1464;-
SPhosphorylation1465;-
SPhosphorylation1784;-
SPhosphorylation1783;-
SPhosphorylation1784;-
SPhosphorylation1783;-
SPhosphorylation1784;-
SPhosphorylation1783;-
SPhosphorylation1744;-
SPhosphorylation1743;-
SPhosphorylation1952;-
SPhosphorylation1954;-
SPhosphorylation1948;-
SPhosphorylation1633;-
SPhosphorylation1635;-
SPhosphorylation1629;-
SPhosphorylation1952;-
SPhosphorylation1954;-
SPhosphorylation1948;-
SPhosphorylation1952;-
SPhosphorylation1954;-
SPhosphorylation1948;-
SPhosphorylation1952;-
SPhosphorylation1954;-
SPhosphorylation1948;-
SPhosphorylation1912;-
SPhosphorylation1914;-
SPhosphorylation1908;-
TPhosphorylation1555;-
TPhosphorylation1236;-
TPhosphorylation1555;-
TPhosphorylation1555;-
TPhosphorylation1555;-
TPhosphorylation1515;-
SPhosphorylation1556;-
SPhosphorylation1237;-
SPhosphorylation1556;-
SPhosphorylation1556;-
SPhosphorylation1556;-
SPhosphorylation1516;-
SPhosphorylation1950;-
SPhosphorylation1631;-
SPhosphorylation1950;-
SPhosphorylation1950;-
SPhosphorylation1950;-
SPhosphorylation1910;-
SPhosphorylation2009;-
SPhosphorylation2011;-
SPhosphorylation1690;-
SPhosphorylation1692;-
SPhosphorylation2009;-
SPhosphorylation2011;-
SPhosphorylation2009;-
SPhosphorylation2011;-
SPhosphorylation2009;-
SPhosphorylation2011;-
SPhosphorylation1969;-
SPhosphorylation1971;-
SPhosphorylation2029;-
SPhosphorylation2031;-
SPhosphorylation1712;-
SPhosphorylation1710;-
SPhosphorylation2029;-
SPhosphorylation2031;-
SPhosphorylation2029;-
SPhosphorylation2031;-
SPhosphorylation2029;-
SPhosphorylation2031;-
SPhosphorylation1989;-
SPhosphorylation1991;-
SPhosphorylation1922;-
SPhosphorylation1926;-
SPhosphorylation1603;-
SPhosphorylation1607;-
SPhosphorylation1922;-
SPhosphorylation1926;-
SPhosphorylation1922;-
SPhosphorylation1926;-
SPhosphorylation1922;-
SPhosphorylation1926;-
SPhosphorylation1882;-
SPhosphorylation1886;-
TPhosphorylation1924;-
TPhosphorylation1605;-
TPhosphorylation1924;-
TPhosphorylation1924;-
TPhosphorylation1924;-
TPhosphorylation1884;-
SPhosphorylation283;-
SPhosphorylation283;-
SPhosphorylation283;-
SPhosphorylation283;-
SPhosphorylation152
SPhosphorylation152
SPhosphorylation152
SPhosphorylation152
SPhosphorylation152
SPhosphorylation152
SPhosphorylation160
SPhosphorylation154
SPhosphorylation160
SPhosphorylation160
SPhosphorylation154
SPhosphorylation160
SPhosphorylation154
SPhosphorylation160
SPhosphorylation154
SPhosphorylation160
SPhosphorylation354
SPhosphorylation354
SPhosphorylation354
SPhosphorylation354
SPhosphorylation354
SPhosphorylation354
SPhosphorylation1016
YPhosphorylation1020
SPhosphorylation697
YPhosphorylation701
SPhosphorylation1016
YPhosphorylation1020
SPhosphorylation1016
YPhosphorylation1020
SPhosphorylation1016
YPhosphorylation1020
SPhosphorylation976
YPhosphorylation980
YPhosphorylation1790
YPhosphorylation1471
YPhosphorylation1790
YPhosphorylation1790
YPhosphorylation1790
YPhosphorylation1750
YPhosphorylation2285
YPhosphorylation2297
SPhosphorylation2099
SPhosphorylation2129
SPhosphorylation1810
SPhosphorylation2129
SPhosphorylation2129
SPhosphorylation2089
TPhosphorylation2163
TPhosphorylation1844
TPhosphorylation2163
TPhosphorylation2163
TPhosphorylation2123
SPhosphorylation910
SPhosphorylation910
SPhosphorylation870
SPhosphorylation1076
SPhosphorylation757
SPhosphorylation1076
SPhosphorylation1076
SPhosphorylation1076
SPhosphorylation1036
SPhosphorylation908
SPhosphorylation908
SPhosphorylation908
SPhosphorylation908
SPhosphorylation868
KAcetylation2055
KAcetylation1736
KAcetylation2055
KAcetylation2055
KAcetylation2055
KAcetylation2015
KAcetylation288
KAcetylation288
KAcetylation288
KAcetylation288
KAcetylation288
KAcetylation288
KAcetylation16
KAcetylation16
KAcetylation16
KAcetylation16
KAcetylation16
KAcetylation16
SPhosphorylation1820
SPhosphorylation1824
SPhosphorylation1501
SPhosphorylation1505
SPhosphorylation1820
SPhosphorylation1824
SPhosphorylation1820
SPhosphorylation1824
SPhosphorylation1820
SPhosphorylation1824
SPhosphorylation1780
SPhosphorylation1784
SPhosphorylation1821
SPhosphorylation1502
SPhosphorylation1821
SPhosphorylation1821
SPhosphorylation1821
SPhosphorylation1781
SPhosphorylation348
SPhosphorylation348
SPhosphorylation348
SPhosphorylation348
SPhosphorylation348
SPhosphorylation348
SPhosphorylation142
SPhosphorylation142
SPhosphorylation142
SPhosphorylation142
SPhosphorylation142
SPhosphorylation142
TPhosphorylation1572
TPhosphorylation1253
TPhosphorylation1572
TPhosphorylation1572
TPhosphorylation1572
TPhosphorylation1532
SPhosphorylation2001
SPhosphorylation2003
SPhosphorylation1682
SPhosphorylation1684
SPhosphorylation2001
SPhosphorylation2003
SPhosphorylation2001
SPhosphorylation2003
SPhosphorylation2001
SPhosphorylation2003
SPhosphorylation1961
SPhosphorylation1963
SPhosphorylation2020
TPhosphorylation2022
SPhosphorylation1701
TPhosphorylation1703
SPhosphorylation2020
TPhosphorylation2022
SPhosphorylation2020
TPhosphorylation2022
SPhosphorylation2020
TPhosphorylation2022
SPhosphorylation1980
TPhosphorylation1982
SPhosphorylation2181
SPhosphorylation1862
SPhosphorylation2181
SPhosphorylation2181
SPhosphorylation2141
SPhosphorylation2102
SPhosphorylation278
SPhosphorylation278
SPhosphorylation278
SPhosphorylation278
SPhosphorylation278
SPhosphorylation278
SPhosphorylation303
SPhosphorylation303
SPhosphorylation303
SPhosphorylation303
SPhosphorylation303
SPhosphorylation303
SPhosphorylation353
SPhosphorylation353
SPhosphorylation353
SPhosphorylation353
SPhosphorylation353
SPhosphorylation353
SPhosphorylation1051
SPhosphorylation1057
SPhosphorylation1068
SPhosphorylation732
SPhosphorylation738
SPhosphorylation749
SPhosphorylation1051
SPhosphorylation1057
SPhosphorylation1068
SPhosphorylation1051
SPhosphorylation1057
SPhosphorylation1068
SPhosphorylation1051
SPhosphorylation1057
SPhosphorylation1068
SPhosphorylation1011
SPhosphorylation1017
SPhosphorylation1028
SPhosphorylation1688
SPhosphorylation1369
SPhosphorylation1688
SPhosphorylation1688
SPhosphorylation1688
SPhosphorylation1648

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

                              
Interactant Gene ID (Source: HPRD) Gene Symbol HPRD ID Ref Seq ID Technique References
55660PRPF40A10995NP_060362.3yeast 2-hybrid15231748   
79753SNIP16999NP_078976.2yeast 2-hybrid15231748   


Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
cd000482371-2408  DSRM
cl000542371-2408  DSRM superfamily
pfam015852305-2348  G-patch
cl026112305-2348  G-patch superfamily
smart004432303-2349  G_patch
pfam147092370-2412  DND1_DSRM
smart003582372-2408  DSRM
pfam084301016-1129  Fork_head_N
cl225401016-1129  Fork_head_N superfamily
pfam126562309-2346  G-patch_2
pfam000352372-2408  dsrm
cd07219359-457  Pat_PNPLA1
cl11396359-457  Patatin_and_cPLA2 superfamily
PHA03247170-460  PHA03247
PHA03379340-673  PHA03379
PHA03247340-647  PHA03247
pfam03154228-576  Atrophin-1
PHA03247386-648  PHA03247
pfam05109281-636  Herpes_BLLF1
PRK108111289-1481  rne
PHA03378181-459  PHA03378
pfam12526369-452  DUF3729
PRK108111220-1381  rne
PRK108111271-1444  rne
TIGR01645312-524  half-pint
PHA03247318-525  PHA03247
PHA03307319-677  PHA03307
PRK07994387-558  PRK07994
TIGR03835135-534  termin_org_DnaJ
PRK108111262-1472  rne
PHA03247386-509  PHA03247
PHA03377138-445  PHA03377
PRK14959365-445  PRK14959
pfam03276383-454  Gag_spuma
PRK10263388-698  PRK10263
PHA03379161-462  PHA03379
PRK12323332-520  PRK12323
PRK14666361-455  uvrC
PRK10263278-457  PRK10263
PRK14951340-460  PRK14951
PHA03291362-451  PHA03291
pfam02993332-446  MCPVI


Ontology Information


   
HPRD ID501
Molecular ClassTranscription factor
Molecular FunctionExtracellular matrix structural constituent (GO:0005201)
Biological ProcessCell growth and/or maintenance (GO:0008151)  



SNP Information


View SNP Geneview Report   

Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO