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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
SP5 389058 Sp5 transcription factor  2- 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
21531130   2011Cell line : -

Source : Czech Central European population Japan

Sample Type : Case control study

No. of Sample : 197 cases and 218 controls

Stage : -

Peptide Nucleic Acid (PNA)-clamp real-time-PCR TaqMan assay, Gene expression profiles.Up-regulation-113 (55 male nad 23 female with average age 65 year)patients who underwent a surgical resection of the primary CRC were included in this study.


Gene Details



Chromosome: 2; NC_000002.11 (171571857..171574498)

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Gene Type protein coding
Gene Family Specificity protein transcription factors, Zinc fingers, C2H2-type
Description -  
Chromosome 2
Location 2q31.1
Start 170714738  
End 170717988  
Strand +  
Gene Sequence

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Length 3251  
OMIM ID 609391   
HGNC ID HGNC:14529   
Unigene ID Hs.368802    
Ensembl ID ENSG00000204335   
PharmGKB ID -   

mRNA Information


mRNA ID XM_011511159.1
Exon join(1..1367,1522..3251)  
mRNA Sequence

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Length 3097  



CDS Information


   
Locationjoin(776..826,1522..2667)
CDS Sequence

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CCDS ID CCDS33322.1



Protein Information


      
Protein IDNP_001003845.1
Protein NameSp5 transcription factor
Molecular Wt. (Da)41833
Protein Sequence

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Length 398  
Uniprot IDP54826
Ensembl Protein ID ENSP00000298743  



Post-translational Modification Information (Source : HPRD)


No matching records could be found.

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

No matching records from HPRD source could be found.

Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
pfam13465342-365  zf-H2C2_2
cl22375342-365  zf-H2C2_2 superfamily
pfam13465312-339  zf-H2C2_2
cl22375312-339  zf-H2C2_2 superfamily
pfam00096356-378  zf-C2H2
cl23491356-378  zf-C2H2 superfamily
pfam00096326-350  zf-C2H2
cl23491326-350  zf-C2H2 superfamily
smart00355356-378  ZnF_C2H2
cl18194356-378  ZnF_C2H2 superfamily
pfam13894356-378  zf-C2H2_4
cl20498356-378  zf-C2H2_4 superfamily
COG4049347-391  COG4049
cl20182347-391  COG4049 superfamily
smart00355326-350  ZnF_C2H2
cl18194326-350  ZnF_C2H2 superfamily
COG5048311-384  COG5048
COG5048328-382  COG5048
PHA0324746-223  PHA03247
COG5048324-383  COG5048
COG5048292-374  COG5048
COG5048288-356  COG5048
PHA00733325-378  PHA00733
PHA0324721-222  PHA03247


Ontology Information


   
HPRD ID2681
Molecular ClassTranscription factor
Molecular FunctionGTPase activity (GO:0003924)
Biological ProcessCell communication (GO:0007154); Signal transduction (GO:0007165)  



SNP Information


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Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO