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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
SQRDL 58472 Sulfide quinone reductase-like (yeast)  15CGI-44; PRO1975 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
20089989   2010Cell line : -

Source : VU University Medical Center, Amsterdam, The Netherlands.

Sample Type : CRC tumor, normal tissue and blood plasma

No. of Sample : -

Stage : TNM Stage II

Biochemical isolation to nano-LC-MS/MS analysis Down-regulation--


Gene Details



Chromosome: 15; NC_000015.9 (45923346..45983492)

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Gene Type protein coding
Gene Family -
Description The protein encoded by this gene may function in mitochondria to catalyze the conversion of sulfide to persulfides, thereby decreasing toxic concencrations of sulfide. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2012]  
Chromosome 15
Location 15q15
Start 45631148  
End 45691294  
Strand -  
Gene Sequence

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Length 60147  
OMIM ID    
HGNC ID HGNC:20390   
Unigene ID Hs.511251    
Ensembl ID ENSG00000137767   
PharmGKB ID -   

mRNA Information


mRNA ID NM_001271213.1
Exon join(1..83,780..872,27760..28010,30808..30978, 38781..38834,42460..42654,44954..45163,51331..51514, 57190..57257,57892..58070,59826..60147)  
mRNA Sequence

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Length 1810  



CDS Information


   
Locationjoin(27777..28010,30808..30978,38781..38834,42460..42654, 44954..45163,51331..51514,57190..57257,57892..58070, 59826..59883)
CDS Sequence

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CCDS ID CCDS10127.1



Protein Information


      
Protein IDNP_001258142.1
Protein NameSulfide quinone reductase-like (yeast)
Molecular Wt. (Da)49830
Protein Sequence

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Length 450  
Uniprot IDQ13642
Ensembl Protein ID ENSP00000071281  



Post-translational Modification Information (Source : HPRD)


Residue Type site
KAcetylation173
KAcetylation180
KAcetylation135
YPhosphorylation415

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

No matching records from HPRD source could be found.

Pathway Information


      
Pathway Name Pathway ID
Sulfur metabolism hsa00920


Structure Information


No matching records could be found.

Domain Information




ID Location Description
pfam1373867-207  Pyr_redox_3
cl2145467-207  NADB_Rossmann superfamily
COG044656-398  FadH2
COG125259-379  Ndh
TIGR03169109-373  Nterm_to_SelD
PTZ0031870-373  PTZ00318


Ontology Information


   
HPRD ID3869
Molecular ClassEnzyme: Oxidoreductase
Molecular FunctionTranscription factor activity (GO:0003700)
Biological ProcessRegulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219)  



SNP Information


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Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO