Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| ST3GAL5 | 8869 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 2 | ST3GalV, SIATGM3S |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 21331762 | 2011 | Cell line : - Source : - Sample Type : CRC tumor and normal tissue No. of Sample : - Stage : - | real-time RT-PCR | Up-regulation | - | ST3GAL5, IFITM3, PDAP1, ALKBH3, NUDT14, CNN2, MAPK14, ACO1, and SEPHS1 may be involved in rectal carcinogenesis. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Sialyltransferases |
| Description | Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. The protein encoded by this gene is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate. The encoded protein is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus. Mutation in this gene has been associated with Amish infantile epilepsy syndrome. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] | Chromosome | 2 |
| Location | 2p11.2 |
| Start | 86066271 |
| End | 86116157 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 49887 |
| OMIM ID | 604402 |
| HGNC ID | HGNC:10872 |
| Unigene ID | Hs.415117 |
| Ensembl ID | ENSG00000115525 |
| PharmGKB ID | PA35773 |
Protein Information
| Protein ID | NP_001035902.1 |
|---|---|
| Protein Name | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 418 |
| Uniprot ID | O60259 |
| Ensembl Protein ID | ENSP00000325072 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Glycosphingolipid biosynthesis - ganglio series | hsa00604 |
| Metabolic pathways | hsa01100 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam00777 | 144-413 | Glyco_transf_29 |
| cl02965 | 144-413 | Glyco_transf_29 superfamily |
Ontology Information
| HPRD ID | 12320 |
|---|---|
| Molecular Class | Enzyme: Sialyltransferase |
| Molecular Function | Catalytic activity (GO:0003824) |
| Biological Process | Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.