Search results:
General Information
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 22733436 | 2012 | Cell line : - Source : - Sample Type : Population-based case-control study No. of Sample : 394 CRC cases and 393 controls Stage : - | SNPshot assay, Multiple logistic regression models | Polymorhpism | - | 6 polymorphisms: rs2072100 (TAC1), rs10198644 (TACR1), rs2193409 (TACR1), rs3771810 (TACR1), and rs4644560 (TACR2). |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | GPCR / Class A : Tachykinin receptors |
| Description | This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neuropeptide substance K, also referred to as neurokinin A. [provided by RefSeq, Jul 2008] | Chromosome | 10 |
| Location | 10q22.1 |
| Start | 71163958 |
| End | 71176674 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 12717 |
| OMIM ID | 162321 |
| HGNC ID | HGNC:11527 |
| Unigene ID | Hs.88372 |
| Ensembl ID | ENSG00000075073 |
| PharmGKB ID | PA36303 |
mRNA Information
| mRNA ID | ?NM_001057.2 |
|---|---|
| Exon | join(1..987,1780..1974,7844..7997,9639..9835,11835..12717) | mRNA Sequence | Download Select all |
| Length | 2416 |
Protein Information
| Protein ID | NP_001048.2 |
|---|---|
| Protein Name | tachykinin receptor 2 |
| Molecular Wt. (Da) | 46120 |
| Protein Sequence | Download Select all |
| Length | 398 |
| Uniprot ID | Q9H1Y0 |
| Ensembl Protein ID | ENSP00000343313 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| N | Glycosylation | 11 |
| N | Glycosylation | 19 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Calcium signaling pathway | hsa04020 |
| Neuroactive ligand-receptor interaction | hsa04080 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam10320 | 46-322 | 7TM_GPCR_Srsx |
| cl21561 | 46-322 | 7tm_4 superfamily |
| pfam00001 | 56-307 | 7tm_1 |
| PHA03087 | 37-307 | PHA03087 |
| PHA02638 | 40-323 | PHA02638 |
| PHA02834 | 40-322 | PHA02834 |
| PHA03235 | 41-323 | PHA03235 |
Ontology Information
| HPRD ID | 7332 |
|---|---|
| Molecular Class | G protein coupled receptor |
| Molecular Function | Sulfotransferase activity (GO:0008146) |
| Biological Process | Metabolism (GO:0008152); Energy pathways (GO:0006091) |
Drug Information
No matching records could be found.