Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| TCERG1L | 256536 | transcription elongation regulator 1-like | 10 | FLJ38950 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 22238052 | 2012 | Cell line : - Source : Department of Pathology, Johns Hopkins University Sample Type : Formalin-fixed and paraffin-embedded primary CRC. No. of Sample : 124 Stage : - | real time RT-PCR, Bisulfite sequencing | Hypermethylation | - | Gene silencing of FBN2 and TCERG1L is associated with promoter DNA hypermethylation in CRC tumors and may be excellent biomarkers for the early detection of CRC. Bisulfite sequencing confirmed cancer-specific methylation of FBN2 and TCERG1L of promoters in colon cancer cell line and cancers but not in normal colon. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | |
| Description | - | Chromosome | 10 |
| Location | 10q26.3 |
| Start | 131092391 |
| End | 131311721 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 219331 |
| OMIM ID | |
| HGNC ID | HGNC:23533 |
| Unigene ID | Hs.126575 |
| Ensembl ID | ENSG00000176769 |
| PharmGKB ID | - |
mRNA Information
| mRNA ID | XM_011539577.1 |
|---|---|
| Exon | join(7..428,2423..2569,3331..3511,51278..51463, 144837..144925,145902..145940,148512..148600, 165062..165216,177274..177343,194788..194923, 207368..207457,213298..213416,218404..219331) | mRNA Sequence | Download Select all |
| Length | 2632 |
CDS Information
| Location | join(87..428,2423..2569,3331..3511,51278..51463, 144837..144925,148512..148600,165062..165216, 177274..177343,194788..194923,207368..207457, 213298..213416,218404..218560) |
|---|---|
| CDS Sequence | Download Select all |
| CCDS ID | CCDS7662.2 |
Protein Information
| Protein ID | NP_777597.2 |
|---|---|
| Protein Name | transcription elongation regulator 1-like |
| Molecular Wt. (Da) | 65529 |
| Protein Sequence | Download Select all |
| Length | 586 |
| Uniprot ID | P36941 |
| Ensembl Protein ID | ENSP00000228918 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| T | Phosphorylation | 281 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00201 | 343-370 | WW |
| cl00157 | 343-370 | WW superfamily |
| pfam01846 | 452-500 | FF |
| cl02610 | 452-500 | FF superfamily |
| pfam01846 | 519-567 | FF |
| cl02610 | 519-567 | FF superfamily |
| smart00441 | 456-502 | FF |
| smart00441 | 519-568 | FF |
| smart00456 | 339-370 | WW |
| COG5104 | 344-584 | PRP40 |
| PRK14951 | 204-299 | PRK14951 |
Ontology Information
| HPRD ID | 2793 |
|---|---|
| Molecular Class | Transcription regulatory protein |
| Molecular Function | Extracellular matrix structural constituent (GO:0005201) |
| Biological Process | Cell growth and/or maintenance (GO:0008151) |
Drug Information
No matching records could be found.