Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| TNFRSF17 | 608 | tumor necrosis factor receptor superfamily, member 17 | 16 | BCM, CD269, TNFRSF13A |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 22108903 | 2012 | Cell line : - Source : Biobank of Wonkwang University Hospital Korea. Sample Type : CRC tumor and normal tissue No. of Sample : 297 CRC and 536 Healthy control Stage : TNM Stage I-IV | High-resolution melting and TaqMan probe analysis | Polymorhpism | - | TNFRSF17 may be a candidate gene associated with the pathogenesis of colon cancer, and the haplotypes of the TNFRSF17 polymorphisms might be one of the markers for colon cancer susceptibility. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Tumor necrosis factor receptor superfamily, "CD molecules" |
| Description | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008] | Chromosome | 16 |
| Location | 16p13.1 |
| Start | 12058964 |
| End | 12061925 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 2962 |
| OMIM ID | 109545 |
| HGNC ID | HGNC:11913 |
| Unigene ID | Hs.2556 |
| Ensembl ID | ENSG00000048462 |
| PharmGKB ID | PA36606 |
mRNA Information
| mRNA ID | NM_001192.2 |
|---|---|
| Exon | join(1..348,1089..1235,2464..2962) | mRNA Sequence | Download Select all |
| Length | 994 |
Protein Information
| Protein ID | NP_001183.2 |
|---|---|
| Protein Name | tumor necrosis factor receptor superfamily, member 17 |
| Molecular Wt. (Da) | 20034 |
| Protein Sequence | Download Select all |
| Length | 184 |
| Uniprot ID | P22894 |
| Ensembl Protein ID | ENSP00000236826 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Cytokine-cytokine receptor interaction | hsa04060 |
| Intestinal immune network for IgA production | hsa04672 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd13414 | 4-166 | TNFRSF17 |
| cl22855 | 4-166 | TNFRSF superfamily |
| pfam09257 | Aug-46 | BCMA-Tall_bind |
| cl07768 | Aug-46 | BCMA-Tall_bind superfamily |
| cd13415 | Aug-51 | TNFRSF13B |
Ontology Information
| HPRD ID | 387 |
|---|---|
| Molecular Class | Cell surface receptor |
| Molecular Function | Metallopeptidase activity (GO:0008237) |
| Biological Process | Protein metabolism (GO:0019538) |
Drug Information
No matching records could be found.