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General Information
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 18710659 | 2008 | Cell line : - Source : - Sample Type : CRC Tumor and normal tissue No. of Sample : 6 Stage : - | MS analysis, 2-DE separation and densitometric analysis | Up-regulation | - | CLIC1 and TPD52 were significantly (P<0.05) up-regulated in all cases of colorectal cancer investigated, irrespective of localization, pTNM stage and grade of colon cancer highlighting their potential to serve as new biomarkers |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | - | Chromosome | 8 |
| Location | 8q21.13 |
| Start | 80947103 |
| End | 81083836 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 136734 |
| OMIM ID | 604068 |
| HGNC ID | HGNC:12005 |
| Unigene ID | Hs.368433 |
| Ensembl ID | ENSG00000076554 |
| PharmGKB ID | PA36686 |
mRNA Information
| mRNA ID | ?NM_001025252.2 |
|---|---|
| Exon | join(1..235,107067..107182,118230..118378,120032..120133, 128992..129040,133432..136792) | mRNA Sequence | Download Select all |
| Length | 4024 |
Protein Information
| Protein ID | NP_001020423.1 |
|---|---|
| Protein Name | tumor protein D52 |
| Molecular Wt. (Da) | 21222 |
| Protein Sequence | Download Select all |
| Length | 224 |
| Uniprot ID | O75121 |
| Ensembl Protein ID | ENSP00000354583 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 131;- |
| S | Phosphorylation | 171;- |
| T | Phosphorylation | 133 |
| T | Phosphorylation | 173 |
| T | Phosphorylation | 156 |
| S | Phosphorylation | 136 |
| S | Phosphorylation | 176 |
| S | Phosphorylation | 159 |
| S | Phosphorylation | 183 |
| S | Phosphorylation | 223 |
| S | Phosphorylation | 206 |
| T | Phosphorylation | 102 |
| T | Phosphorylation | 142 |
| T | Phosphorylation | 102 |
| S | Phosphorylation | 119 |
| S | Phosphorylation | 159 |
| S | Phosphorylation | 119 |
| T | Phosphorylation | 91 |
| T | Phosphorylation | 131 |
| T | Phosphorylation | 91 |
| Y | Phosphorylation | 96 |
| Y | Phosphorylation | 136 |
| Y | Phosphorylation | 96 |
| S | Phosphorylation | 154 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 7165 | TPD52L2 | 11947 | NP_955392.1 | yeast 2-hybrid | 9484778 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Ontology Information
| HPRD ID | 7234 |
|---|---|
| Molecular Class | Unclassified |
| Molecular Function | Molecular function unknown (GO:0005554) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.