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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
TRIM15 89870 tripartite motif containing 15  6ZNFB7, RNF93 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
25450970   2015Cell line : HCT116, HT-29, and LOVO cells

Source : -

Sample Type : -

No. of Sample : -

Stage : -

Fluorescent protein complementation assay,Co-precipitation and immunoblotting,Immunohistochemistry,Soft agar assay for colony formation.Down-regulation- TRIM15 as an additional component of the integrin adhesome, regulating cell migration, and suggest that TRIM15 may function as a tumor suppressor of colon cancer.


Gene Details



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Gene Type protein coding
Gene Family Tripartite motif containing / Tripartite motif containing, "RING-type (C3HC4) zinc fingers"
Description -  
Chromosome 6
Location 6p21.33
Start 0  
End 0  
Strand  
Gene Sequence

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Length -  
OMIM ID -   
HGNC ID HGNC:16284   
Unigene ID Hs.591789   
Ensembl ID ENSG00000204610   
PharmGKB ID PA38114   

mRNA Information


mRNA ID ?NM_033229.2
Exon  
mRNA Sequence

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Length  



CDS Information


   
Location
CDS Sequence

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CCDS ID CCDS4677.1



Protein Information


      
Protein IDNP_150232.2
Protein Nametripartite motif containing 15
Molecular Wt. (Da)0
Protein Sequence

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Length 465  
Uniprot IDQ96CG8
Ensembl Protein ID ENSP00000330523  



Post-translational Modification Information (Source : HPRD)


No matching records could be found.

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

No matching records from HPRD source could be found.

Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
cd12888296-463  SPRY_PRY_TRIM7_like
cl02614296-463  SPRY superfamily
cd0002181-119  BBOX
cl0003481-119  BBOX superfamily
cd0016216-63  RING
cl1723816-63  RING superfamily
cd12900296-463  SPRY_PRY_Btn_TRIMs
cd12905296-452  SPRY_PRY_TRIM_Bty_69_NF7
cd13733296-458  SPRY_PRY_C-IV_1
cd12893296-452  SPRY_PRY_TRIM35
cd13740296-463  SPRY_PRY_TRIM7
cd12897296-452  SPRY_PRY_TRIM50_62_72
cd13745294-452  SPRY_PRY_TRIM39
cd12874296-455  SPRY_PRY
cd12891296-464  SPRY_PRY_C-IV_2
cd13741296-463  SPRY_PRY_TRIM41
cd13734298-463  SPRY_PRY_C-I
smart00449346-460  SPRY
cd13744296-453  SPRY_PRY_TRIM62
cd13743265-450  SPRY_PRY_TRIM50
cd12904296-454  SPRY_BSPRY
cd13738297-456  SPRY_PRY_TRIM14
pfam13765296-344  PRY
cl02686296-344  PRY superfamily
smart00589296-344  PRY
pfam00622346-459  SPRY
cd13742296-454  SPRY_PRY_TRIM72
cd12902296-452  SPRY_PRY_RNF135
cd12903298-465  SPRY_PRY_SPRYD4
cd13736296-463  SPRY_PRY_TRIM25
cd12892298-463  SPRY_PRY_TRIM18
cd12898301-460  SPRY_PRY_TRIM76
cd12896296-463  SPRY_PRY_TRIM65
cd12890296-457  SPRY_PRY_TRIM16
cd12899298-463  SPRY_PRY_TRIM76_like
cd12901331-455  SPRY_PRY_FSD1
cd11709347-454  SPRY
smart0033680-119  BBOX
pfam1522716-60  zf-C3HC4_4
pfam0064380-116  zf-B_box
cd13739298-465  SPRY_PRY_TRIM1
cd12889297-454  SPRY_PRY_TRIM67_9
pfam0009716-60  zf-C3HC4
smart0018416-60  RING
pfam03938119-212  OmpH
cl21485119-212  OmpH superfamily
pfam1392316-60  zf-C3HC4_2
smart00502130-184  BBC
cl17972130-184  BBC superfamily
COG5432May-65  RAD18
TIGR02169121-241  SMC_prok_A
COG557416-65  PEX10
PRK11448119-183  hsdR
TIGR00599May-65  rad18
TIGR02168121-223  SMC_prok_B
COG1196127-226  Smc
TIGR02168130-247  SMC_prok_B
COG1196127-237  Smc
COG3096111-241  MukB
COG0419119-246  SbcC
COG1196121-234  Smc
TIGR04523142-226  Mplasa_alph_rch
pfam12128129-255  DUF3584
TIGR02168127-234  SMC_prok_B
pfam12128128-248  DUF3584
TIGR02169119-225  SMC_prok_A
pfam08317121-228  Spc7
COG1340131-248  COG1340
TIGR02168121-234  SMC_prok_B
pfam04156130-247  IncA
pfam05911119-289  DUF869
PRK03918119-234  PRK03918
TIGR02169118-324  SMC_prok_A


Ontology Information


   
HPRD ID14470
Molecular ClassUnclassified
Molecular FunctionDNA binding (GO:0003677)
Biological ProcessRegulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219)  



SNP Information


View SNP Geneview Report   

Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO