Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| TRIO | 7204 | trio Rho guanine nucleotide exchange factor  | 5 | ARHGEF23  |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 25432929    | 2015 | Cell line : - Source : - Sample Type : - No. of Sample : - Stage : - | - | Phosphorylation | - | TRIO pY2681 is one of the downstream effectors of NOTCH signaling activation in colorectal cancer, and can be a prognostic marker, helping to determine the therapeutic modality of patients with colorectal cancer. |
Gene Details

| Gene Type | protein coding |
|---|---|
| Gene Family | Rho guanine nucleotide exchange factors, "Immunoglobulin superfamily / I-set domain containing" |
| Description | This gene encodes a large protein that functions as a GDP to GTP exchange factor. This protein promotes the reorganization of the actin cytoskeleton, thereby playing a role in cell migration and growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]   | Chromosome | 5 |
| Location | 5p14-p15.1 |
| Start | 14143817   |
| End | 14510313   |
| Strand | +   |
| Gene Sequence |    Download   Select all |
| Length | 366497   |
| OMIM ID | 601893    |
| HGNC ID | HGNC:12303    |
| Unigene ID | Hs.130031    |
| Ensembl ID | ENSG00000038382    |
| PharmGKB ID | PA36982    |
mRNA Information
| mRNA ID | ?NM_007118.2 |
|---|---|
| Exon | join(1..175,127118..127192,136615..136729,143164..143356, 147009..147521,149305..149427,153365..153556, 160754..160885,172806..173036,187071..187193, 192829..193020,214471..214640,215650..215824, 220025..220220,220943..221109,223153..223272, 225001..225192,225667..225816,230522..230636, 234305..234420,237423..237545,243731..243925, 244025..244140,244906..244972,245582..245691, 246524..246593,247194..247283,250331..250423, 253336..253447,255173..255363,257256..257357, 262141..262283,262866..262965,276071..276314, 276751..277088)   | mRNA Sequence |    Download   Select all |
| Length | 5559   |
CDS Information
| Location | 19..5280 |
|---|---|
| CDS Sequence |    Download   Select all |
| CCDS ID | CCDS3883.1 |    
Protein Information
| Protein ID | NP_009049.2 |
|---|---|
| Protein Name | trio Rho guanine nucleotide exchange factor |
| Molecular Wt. (Da) | 142096 |
| Protein Sequence |    Download   Select all |
| Length | 3097   |
| Uniprot ID | O95750 |    
| Ensembl Protein ID | ENSP00000294312   |    
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| Y | Phosphorylation | 2796 |
| T | Phosphorylation | 1903;- |
| S | Phosphorylation | 2282 |
| S | Phosphorylation | 2455 |
| S | Phosphorylation | 2467 |
| S | Phosphorylation | 2459 |
| S | Phosphorylation | 2429 |
| S | Phosphorylation | 2462 |
| S | Phosphorylation | 1779 |
| S | Phosphorylation | 2417 |
| S | Phosphorylation | 2440 |
| T | Phosphorylation | 2281 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING)      View   
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 387 |    RHOA |    1323 |    NP_001655.1 |    in vitro |    10948190    |
| 2316 |    FLNA |    2060 |    NP_001104026.1 |    in vitro;yeast 2-hybrid |    11146652    |
| 5792 |    PTPRF |    1552 |    NP_002831.2 |    in vitro;in vivo |    8643598    |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd14113 | 2788-3050  | STKc_Trio_C |
| cl21453 | 2788-3050  | PKc_like superfamily |
| cd13241 | 2148-2286  | PH2_Kalirin_Trio_p63RhoGEF |
| cl17171 | 2148-2286  | PH-like superfamily |
| cd13240 | 1472-1594  | PH1_Kalirin_Trio_like |
| cl17171 | 1472-1594  | PH-like superfamily |
| cd00160 | 1970-2143  | RhoGEF |
| cl02571 | 1970-2143  | RhoGEF superfamily |
| cd00160 | 1295-1465  | RhoGEF |
| cl02571 | 1295-1465  | RhoGEF superfamily |
| cd11853 | 2555-2613  | SH3_Kalirin_2 |
| cl17036 | 2555-2613  | SH3 superfamily |
| cd11852 | 1659-1718  | SH3_Kalirin_1 |
| cl17036 | 1659-1718  | SH3 superfamily |
| cd00176 | 567-783  | SPEC |
| cl02488 | 567-783  | SPEC superfamily |
| cd00176 | 908-1137  | SPEC |
| cl02488 | 908-1137  | SPEC superfamily |
| cd00176 | 341-566  | SPEC |
| cl02488 | 341-566  | SPEC superfamily |
| cd00176 | 787-1014  | SPEC |
| cl02488 | 787-1014  | SPEC superfamily |
| cd00170 | 67-204  | SEC14 |
| cl15787 | 67-204  | SEC14 superfamily |
| cd00176 | 230-445  | SPEC |
| cl02488 | 230-445  | SPEC superfamily |
| cd00176 | 1139-1246  | SPEC |
| cl02488 | 1139-1246  | SPEC superfamily |
| cd14006 | 2802-3049  | STKc_MLCK-like |
| cd14115 | 2802-3049  | STKc_Kalirin_C |
| cd05117 | 2801-3049  | STKc_CAMK |
| cd14103 | 2802-3050  | STKc_MLCK |
| cd14105 | 2790-3050  | STKc_DAPK |
| cd14194 | 2790-3050  | STKc_DAPK1 |
| cd14106 | 2789-3050  | STKc_DRAK |
| cd14195 | 2790-3052  | STKc_DAPK3 |
| cd14196 | 2791-3050  | STKc_DAPK2 |
| cd14197 | 2801-3050  | STKc_DRAK1 |
| cd14198 | 2790-3050  | STKc_DRAK2 |
| cd14107 | 2794-3050  | STKc_obscurin_rpt1 |
| cd14114 | 2795-3050  | STKc_Twitchin_like |
| cd14085 | 2792-3074  | STKc_CaMKIV |
| cd14003 | 2802-3049  | STKc_AMPK-like |
| cd14087 | 2796-3050  | STKc_PSKH1 |
| cd14007 | 2802-3051  | STKc_Aurora |
| cd14083 | 2802-3049  | STKc_CaMKI |
| cd14191 | 2795-3050  | STKc_MLCK1 |
| cd14192 | 2802-3050  | STKc_MLCK3 |
| cd05123 | 2802-3044  | STKc_AGC |
| cd14098 | 2796-3049  | STKc_Rad53_Cds1 |
| cd14193 | 2793-3050  | STKc_MLCK4 |
| cd14169 | 2793-3053  | STKc_CaMKI_beta |
| cd14190 | 2802-3050  | STKc_MLCK2 |
| cd14095 | 2796-3049  | STKc_DCKL |
| pfam00621 | 1973-2144  | RhoGEF |
| cd14099 | 2796-3050  | STKc_PLK |
| cd14167 | 2789-3050  | STKc_CaMKI_alpha |
| smart00325 | 1973-2144  | RhoGEF |
| cd14108 | 2795-3050  | STKc_SPEG_rpt1 |
| cd05581 | 2801-3041  | STKc_PDK1 |
| cd14166 | 2802-3054  | STKc_CaMKI_gamma |
| cd05579 | 2804-3041  | STKc_MAST_like |
| cd14185 | 2802-3049  | STKc_DCKL3 |
| cd14104 | 2801-3065  | STKc_Titin |
| cd14091 | 2801-3054  | STKc_RSK_C |
| cd14093 | 2802-3050  | STKc_PhKG |
| cd14086 | 2801-3050  | STKc_CaMKII |
| cd14014 | 2796-3045  | STKc_PknB_like |
| cd14081 | 2802-3050  | STKc_BRSK1_2 |
| cd14080 | 2802-3050  | STKc_TSSK-like |
| cd00180 | 2802-3046  | PKc |
| cd14084 | 2802-3050  | STKc_Chk2 |
| cd14009 | 2802-3038  | STKc_ATG1_ULK_like |
| smart00325 | 1296-1466  | RhoGEF |
| cd14079 | 2802-3050  | STKc_AMPK_alpha |
| cd06606 | 2802-3050  | STKc_MAPKKK |
| cd14092 | 2797-3074  | STKc_MSK_C |
| cd14096 | 2796-3050  | STKc_RCK1-like |
| pfam00621 | 1296-1466  | RhoGEF |
| cd14183 | 2802-3050  | STKc_DCKL1 |
| cd14168 | 2788-3092  | STKc_CaMKI_delta |
| cd14184 | 2802-3049  | STKc_DCKL2 |
| cd14176 | 2792-3050  | STKc_RSK2_C |
| cd05122 | 2796-3050  | PKc_STE |
| cd05580 | 2799-3038  | STKc_PKA_like |
| cd14082 | 2802-3049  | STKc_PKD |
| cd14109 | 2818-3050  | PK_Unc-89_rpt1 |
| cd14111 | 2796-3050  | STKc_SPEG_rpt2 |
| cd14110 | 2796-3050  | STKc_obscurin_rpt2 |
| cd14078 | 2796-3050  | STKc_MELK |
| cd14097 | 2796-3050  | STKc_STK33 |
| cd14209 | 2790-3038  | STKc_PKA |
| cd05572 | 2802-3038  | STKc_cGK |
| cd14175 | 2802-3050  | STKc_RSK1_C |
| cd14002 | 2798-3038  | STKc_STK36 |
| cd14074 | 2802-3050  | STKc_SNRK |
| cd14663 | 2802-3049  | STKc_SnRK3 |
| cd14178 | 2792-3050  | STKc_RSK3_C |
| cd14075 | 2794-3050  | STKc_NIM1 |
| cd14094 | 2792-3094  | STKc_CASK |
| cd14073 | 2802-2992  | STKc_NUAK |
| cd06614 | 2795-3051  | STKc_PAK |
| cd14177 | 2792-3050  | STKc_RSK4_C |
| cd14179 | 2802-3063  | STKc_MSK1_C |
| cd06623 | 2799-3051  | PKc_MAPKK_plant_like |
| cd14162 | 2802-3050  | STKc_TSSK4-like |
| cd14181 | 2802-3046  | STKc_PhKG2 |
| cd06627 | 2801-3050  | STKc_Cdc7_like |
| cd14088 | 2829-3050  | STKc_CaMK_like |
| cd14004 | 2796-3050  | STKc_PASK |
| cd14008 | 2802-3050  | STKc_LKB1_CaMKK |
| cd14071 | 2795-3050  | STKc_SIK |
| cd05118 | 2796-3050  | STKc_CMGC |
| cd05573 | 2802-3031  | STKc_ROCK_NDR_like |
| cd14161 | 2796-2992  | STKc_NUAK2 |
| cd14010 | 2801-3038  | STKc_ULK4 |
| cd08215 | 2796-3046  | STKc_Nek |
| cd14072 | 2796-3050  | STKc_MARK |
| cd14182 | 2802-3051  | STKc_PhKG1 |
| pfam13716 | 75-211  | CRAL_TRIO_2 |
| cd05574 | 2799-3038  | STKc_phototropin_like |
| cd14201 | 2793-2999  | STKc_ULK2 |
| cd14163 | 2802-3050  | STKc_TSSK3-like |
| cd14090 | 2796-3049  | STKc_Mnk |
| cd14116 | 2802-3050  | STKc_Aurora-A |
| cd14165 | 2802-3050  | STKc_TSSK1_2-like |
| cd14069 | 2796-3050  | STKc_Chk1 |
| cd14121 | 2802-3040  | STKc_ULK3 |
| cd14187 | 2802-3053  | STKc_PLK1 |
| cd05578 | 2803-3038  | STKc_Yank1 |
| cd14070 | 2802-3050  | STKc_HUNK |
| cd05585 | 2802-3038  | STKc_YPK1_like |
| cd14186 | 2802-3045  | STKc_PLK4 |
| cd14120 | 2802-3038  | STKc_ULK1_2-like |
| cd08224 | 2801-3046  | STKc_Nek6_7 |
| cd05570 | 2802-3048  | STKc_PKC |
| cd14077 | 2796-3050  | STKc_Kin1_2 |
| cd14180 | 2802-3063  | STKc_MSK2_C |
| cd14202 | 2802-2999  | STKc_ULK1 |
| cd14665 | 2796-3049  | STKc_SnRK2-3 |
| cd07829 | 2796-3050  | STKc_CDK_like |
| cd05571 | 2802-3038  | STKc_PKB |
| cd05575 | 2802-3038  | STKc_SGK |
| cd08530 | 2796-3048  | STKc_CNK2-like |
| cd05611 | 2801-3038  | STKc_Rim15_like |
| cd14112 | 2796-3050  | STKc_Unc-89_rpt2 |
| cd06612 | 2802-3041  | STKc_MST1_2 |
| cd06609 | 2794-3075  | STKc_MST3_like |
| cd05586 | 2802-3041  | STKc_Sck1_like |
| cd05609 | 2804-3046  | STKc_MAST |
| cd14164 | 2802-3050  | STKc_TSSK6-like |
| cd05595 | 2802-3038  | STKc_PKB_beta |
| cd05577 | 2802-3038  | STKc_GRK |
| cd14173 | 2802-3050  | STKc_Mnk2 |
| cd13994 | 2802-3050  | STKc_HAL4_like |
| cd05584 | 2803-3047  | STKc_p70S6K |
| cd14117 | 2802-3056  | STKc_Aurora-B_like |
| cd14133 | 2798-3050  | PKc_DYRK_like |
| cd13241 | 1470-1605  | PH2_Kalirin_Trio_p63RhoGEF |
| cd14662 | 2796-3038  | STKc_SnRK2 |
| cd06625 | 2802-3049  | STKc_MEKK3_like |
| cd05601 | 2802-3038  | STKc_CRIK |
| cd14174 | 2802-3051  | STKc_Mnk1 |
| cd06632 | 2802-3047  | STKc_MEKK1_plant |
| cd05603 | 2802-3047  | STKc_SGK2 |
| cd14005 | 2796-3050  | STKc_PIM |
| cd05600 | 2799-3004  | STKc_Sid2p_like |
| cd14118 | 2801-3038  | STKc_CAMKK |
| cd14101 | 2802-3051  | STKc_PIM2 |
| cd08228 | 2801-3046  | STKc_Nek6 |
| cd05602 | 2802-3038  | STKc_SGK1 |
| cd06611 | 2791-3051  | STKc_SLK_like |
| cd05593 | 2802-3038  | STKc_PKB_gamma |
| cd05599 | 2803-3031  | STKc_NDR_like |
| cd07841 | 2796-3049  | STKc_CDK7 |
| cd05592 | 2802-3038  | STKc_nPKC_theta_like |
| cd05604 | 2802-3038  | STKc_SGK3 |
| cd13990 | 2802-3039  | STKc_TLK |
| cd08529 | 2801-3050  | STKc_FA2-like |
| cd05583 | 2805-3038  | STKc_MSK_N |
| cd14089 | 2802-3049  | STKc_MAPKAPK |
| cd05594 | 2802-3038  | STKc_PKB_alpha |
| cd14171 | 2802-3050  | STKc_MAPKAPK5 |
| cd08217 | 2796-3046  | STKc_Nek2 |
| cd07833 | 2796-3050  | STKc_CDKL |
| cd08220 | 2796-3039  | STKc_Nek8 |
| cd14189 | 2802-3040  | STKc_PLK3 |
| cd14119 | 2802-3040  | STKc_LKB1 |
| cd05598 | 2794-3004  | STKc_LATS |
| cd13987 | 2802-3042  | STKc_SBK1 |
| cd05630 | 2802-3038  | STKc_GRK6 |
| cd13999 | 2802-3040  | STKc_MAP3K-like |
| cd05612 | 2796-3038  | STKc_PRKX_like |
| cd06605 | 2799-3052  | PKc_MAPKK |
| cd14076 | 2802-3050  | STKc_Kin4 |
| cd14199 | 2801-3051  | STKc_CaMKK2 |
| cd05613 | 2805-3038  | STKc_MSK1_N |
| cd14172 | 2802-3050  | STKc_MAPKAPK3 |
| cd05582 | 2802-3038  | STKc_RSK_N |
| cd06610 | 2796-3042  | STKc_OSR1_SPAK |
| cd14100 | 2802-3050  | STKc_PIM1 |
| cd06917 | 2794-3052  | STKc_NAK1_like |
| cd06628 | 2835-3042  | STKc_Byr2_like |
| cd06621 | 2798-3052  | PKc_Pek1_like |
| cd14102 | 2796-3050  | STKc_PIM3 |
| cd06642 | 2793-3074  | STKc_STK25 |
| cd05605 | 2802-3038  | STKc_GRK4_like |
| smart00516 | 69-204  | SEC14 |
| cd07832 | 2796-3050  | STKc_CCRK |
| cd05631 | 2802-3038  | STKc_GRK4 |
| cd06643 | 2791-2991  | STKc_SLK |
| cd07838 | 2796-3046  | STKc_CDK4_6_like |
| cd13242 | 2140-2273  | PH_puratrophin-1 |
| cd05587 | 2802-3038  | STKc_cPKC |
| cd14037 | 2802-3040  | STKc_NAK_like |
| cd13242 | 1462-1598  | PH_puratrophin-1 |
| cd13997 | 2796-3042  | PKc_Wee1_like |
| cd06626 | 2835-3050  | STKc_MEKK4 |
| cd06648 | 2789-3050  | STKc_PAK_II |
| cd14170 | 2848-3066  | STKc_MAPKAPK2 |
| cd13989 | 2802-2993  | STKc_IKK |
| cd07860 | 2796-3049  | STKc_CDK2_3 |
| cd14135 | 2796-2988  | STKc_PRP4 |
| cd01227 | 1475-1590  | PH_Dbs |
| cd06631 | 2802-3050  | STKc_YSK4 |
| cd14200 | 2796-3038  | STKc_CaMKK1 |
| cd07861 | 2796-3045  | STKc_CDK1_euk |
| cd14188 | 2802-3050  | STKc_PLK2 |
| cd05597 | 2802-3038  | STKc_DMPK_like |
| cd05617 | 2780-3038  | STKc_aPKC_zeta |
| cd05621 | 2796-3033  | STKc_ROCK2 |
| cd05622 | 2796-3033  | STKc_ROCK1 |
| cd06644 | 2799-3054  | STKc_STK10 |
| cd13993 | 2796-3038  | STKc_Pat1_like |
| cd05588 | 2802-2992  | STKc_aPKC |
| cd08222 | 2796-3046  | STKc_Nek11 |
| cd05616 | 2802-3038  | STKc_cPKC_beta |
| cd05596 | 2796-3030  | STKc_ROCK |
| cd05624 | 2802-3027  | STKc_MRCK_beta |
| cd05589 | 2799-3038  | STKc_PKN |
| cd07835 | 2796-3050  | STKc_CDK1_CdkB_like |
| cd14038 | 2802-2993  | STKc_IKK_beta |
| cd05618 | 2802-2992  | STKc_aPKC_iota |
| cd06647 | 2796-3051  | STKc_PAK_I |
| cd13985 | 2796-3042  | STKc_GAK_like |
| cd06641 | 2793-3074  | STKc_MST3 |
| cd05614 | 2805-3088  | STKc_MSK2_N |
| cd05608 | 2802-3038  | STKc_GRK1 |
| cd05629 | 2796-3014  | STKc_NDR_like_fungal |
| cd05615 | 2802-3038  | STKc_cPKC_alpha |
| cd06640 | 2793-3074  | STKc_MST4 |
| cd08225 | 2796-3050  | STKc_Nek5 |
| cd05591 | 2802-3038  | STKc_nPKC_epsilon |
| cd14134 | 2790-3050  | PKc_CLK |
| cd05619 | 2802-3038  | STKc_nPKC_theta |
| cd06659 | 2801-3053  | STKc_PAK6 |
| cd08221 | 2834-3045  | STKc_Nek9 |
| cd05590 | 2802-3038  | STKc_nPKC_eta |
| cd05610 | 2796-3041  | STKc_MASTL |
| cd05632 | 2802-3038  | STKc_GRK5 |
| cd05620 | 2802-3038  | STKc_nPKC_delta |
| cd14229 | 2802-3053  | STKc_HIPK3 |
| cd06613 | 2796-3046  | STKc_MAP4K3_like |
| cd08229 | 2801-3039  | STKc_Nek7 |
| cd14066 | 2802-3045  | STKc_IRAK |
| cd13996 | 2792-3047  | STKc_EIF2AK |
| cd05607 | 2793-3038  | STKc_GRK7 |
| cd07846 | 2796-2996  | STKc_CDKL2_3 |
| cd14137 | 2796-3046  | STKc_GSK3 |
| cd07840 | 2796-3049  | STKc_CDK9_like |
| cd00192 | 2801-3040  | PTKc |
| cd07851 | 2796-3050  | STKc_p38 |
| cd06622 | 2801-3052  | PKc_PBS2_like |
| cd06630 | 2802-3046  | STKc_MEKK1 |
| cd14039 | 2802-2993  | STKc_IKK_alpha |
| cd13240 | 2151-2271  | PH1_Kalirin_Trio_like |
| cd13979 | 2800-2995  | STKc_Mos |
| cd06620 | 2799-3052  | PKc_Byr1_like |
| cd14136 | 2790-3050  | STKc_SRPK |
| cd07847 | 2796-2989  | STKc_CDKL1_4 |
| cd07845 | 2802-3051  | STKc_CDK10 |
| cd05627 | 2790-3027  | STKc_NDR2 |
| cd06654 | 2796-3051  | STKc_PAK1 |
| cd06655 | 2796-3051  | STKc_PAK2 |
| cd06650 | 2793-3048  | PKc_MEK1 |
| cd08219 | 2840-3045  | STKc_Nek3 |
| cd05628 | 2796-3027  | STKc_NDR1 |
| cd14000 | 2802-3041  | STKc_LRRK |
| cd07830 | 2796-3050  | STKc_MAK_like |
| cd07855 | 2792-3051  | STKc_ERK5 |
| cd08218 | 2796-3040  | STKc_Nek1 |
| cd06652 | 2802-2992  | STKc_MEKK2 |
| cd06653 | 2802-2992  | STKc_MEKK3_like_u1 |
| cd06629 | 2835-3050  | STKc_Bck1_like |
| cd06656 | 2796-2996  | STKc_PAK3 |
| cd07871 | 2796-3032  | STKc_PCTAIRE3 |
| cd06624 | 2802-3050  | STKc_ASK |
| cd07836 | 2796-3049  | STKc_Pho85 |
| cd14212 | 2802-2979  | PKc_YAK1 |
| cd14052 | 2799-2981  | PTKc_Wee1_fungi |
| cd14211 | 2798-2979  | STKc_HIPK |
| cd06658 | 2801-3051  | STKc_PAK5 |
| cd07873 | 2796-3041  | STKc_PCTAIRE1 |
| cd07863 | 2796-3050  | STKc_CDK4 |
| cd14210 | 2796-3050  | PKc_DYRK |
| cd05626 | 2794-3004  | STKc_LATS2 |
| cd05623 | 2802-3027  | STKc_MRCK_alpha |
| cd13991 | 2802-3047  | STKc_NIK |
| cd07852 | 2802-3052  | STKc_MAPK15-like |
| cd05606 | 2802-3038  | STKc_beta_ARK |
| cd07853 | 2802-3056  | STKc_NLK |
| cd05625 | 2794-3004  | STKc_LATS1 |
| cd14059 | 2822-2996  | STKc_MAP3K12_13 |
| cd14068 | 2802-3042  | STKc_LRRK2 |
| cd05112 | 2799-3047  | PTKc_Itk |
| cd07834 | 2802-3051  | STKc_MAPK |
| cd14050 | 2796-3042  | PKc_Myt1 |
| cd07831 | 2796-3046  | STKc_MOK |
| cd05633 | 2802-3038  | STKc_GRK3 |
| cd06657 | 2794-3050  | STKc_PAK4 |
| cd14132 | 2782-2981  | STKc_CK2_alpha |
| cd07866 | 2796-3049  | STKc_BUR1 |
| cd13983 | 2801-2963  | STKc_WNK |
| cd05060 | 2801-2992  | PTKc_Syk_like |
| cd07848 | 2802-3017  | STKc_CDKL5 |
| cd07878 | 2796-2992  | STKc_p38beta |
| cd07856 | 2796-3050  | STKc_Sty1_Hog1 |
| cd14223 | 2802-3038  | STKc_GRK2 |
| cd07872 | 2796-3020  | STKc_PCTAIRE2 |
| cd06633 | 2788-3097  | STKc_TAO3 |
| cd06639 | 2799-3051  | STKc_myosinIIIB_N |
| cd07862 | 2796-2981  | STKc_CDK6 |
| cd14226 | 2802-2979  | PKc_DYRK1 |
| cd14001 | 2823-3042  | PKc_TOPK |
| cd06651 | 2802-3051  | STKc_MEKK3 |
| cd14049 | 2796-3048  | STKc_EIF2AK1_HRI |
| cd06615 | 2796-3051  | PKc_MEK |
| cd07877 | 2796-3032  | STKc_p38alpha |
| cd06608 | 2799-3050  | STKc_myosinIII_N_like |
| cd05059 | 2799-3039  | PTKc_Tec_like |
| cd08528 | 2796-3039  | STKc_Nek10 |
| cd06638 | 2792-3050  | STKc_myosinIIIA_N |
| cd13978 | 2802-2994  | STKc_RIP |
| cd06649 | 2793-2991  | PKc_MEK2 |
| cd14041 | 2802-3027  | STKc_TLK2 |
| cd14146 | 2804-3047  | STKc_MLK4 |
| cd14148 | 2835-3047  | STKc_MLK2 |
| cd14131 | 2795-2996  | PKc_Mps1 |
| cd13239 | 1472-1593  | PH_Obscurin |
| cd05116 | 2801-2993  | PTKc_Syk |
| cd05148 | 2801-3006  | PTKc_Srm_Brk |
| cd01227 | 2153-2273  | PH_Dbs |
| cd14018 | 2896-3044  | STKc_PINK1 |
| smart00150 | 1143-1243  | SPEC |
| cd14227 | 2798-2988  | STKc_HIPK2 |
| cd07850 | 2796-3046  | STKc_JNK |
| smart00150 | 571-671  | SPEC |
| cd04969 | 2699-2776  | Ig5_Contactin_like |
| cl11960 | 2699-2776  | Ig superfamily |
| cd06619 | 2802-3073  | PKc_MKK5 |
| cd13995 | 2804-3050  | STKc_MAP3K8 |
| cd06607 | 2796-3051  | STKc_TAO |
| cd07880 | 2796-2992  | STKc_p38gamma |
| cd05039 | 2800-3047  | PTKc_Csk_like |
| cd14228 | 2798-2988  | STKc_HIPK1 |
| cd06618 | 2799-3051  | PKc_MKK7 |
| cd14046 | 2796-3046  | STKc_EIF2AK4_GCN2_rpt2 |
| cd14012 | 2840-3041  | PK_eIF2AK_GCN2_rpt1 |
| cd13982 | 2903-3046  | STKc_IRE1 |
| cd14061 | 2802-2992  | STKc_MLK |
| cd05040 | 2801-2980  | PTKc_Ack_like |
| cd07865 | 2788-3049  | STKc_CDK9 |
| cd14145 | 2835-2992  | STKc_MLK1 |
| cd14040 | 2802-3027  | STKc_TLK1 |
| cd00176 | 676-907  | SPEC |
| cd06645 | 2799-3050  | STKc_MAP4K3 |
| cd14031 | 2801-2963  | STKc_WNK3 |
| cd05091 | 2801-3039  | PTKc_Ror2 |
| cd05067 | 2799-3040  | PTKc_Lck_Blk |
| cd07839 | 2796-3046  | STKc_CDK5 |
| cd07844 | 2796-3050  | STKc_PCTAIRE_like |
| cd06635 | 2788-3097  | STKc_TAO1 |
| cd07837 | 2796-3046  | STKc_CdkB_plant |
| cd14033 | 2801-2963  | STKc_WNK4 |
| cd06634 | 2788-3051  | STKc_TAO2 |
| cd14225 | 2794-3026  | PKc_DYRK4 |
| cd14030 | 2801-2963  | STKc_WNK1 |
| cd05038 | 2799-2993  | PTKc_Jak_rpt2 |
| cd05725 | 2702-2776  | Ig3_Robo |
| cd05082 | 2802-3051  | PTKc_Csk |
| cd07857 | 2796-3027  | STKc_MPK1 |
| cd07874 | 2796-3050  | STKc_JNK3 |
| cd13986 | 2802-3040  | STKc_16 |
| cd00176 | 450-671  | SPEC |
| cd14158 | 2802-2992  | STKc_IRAK4 |
| cd07869 | 2796-2992  | STKc_PFTAIRE1 |
| cd05115 | 2801-2992  | PTKc_Zap-70 |
| cd14060 | 2803-2992  | STKc_MLTK |
| cd05114 | 2801-2992  | PTKc_Tec_Rlk |
| smart00150 | 910-1008  | SPEC |
| cd13968 | 2802-2938  | PKc_like |
| cd05034 | 2802-2983  | PTKc_Src_like |
| cd06646 | 2796-3050  | STKc_MAP4K5 |
| cd05113 | 2801-2992  | PTKc_Btk_Bmx |
| cd07875 | 2796-2981  | STKc_JNK1 |
| cd00096 | 2702-2773  | Ig |
| cd05056 | 2802-2992  | PTKc_FAK |
| smart00150 | 345-445  | SPEC |
| cd07876 | 2826-2988  | STKc_JNK2 |
| cd06636 | 2799-2994  | STKc_MAP4K4_6_N |
| cd07879 | 2796-2992  | STKc_p38delta |
| cd14032 | 2801-2963  | STKc_WNK2_like |
| cd14216 | 2790-2999  | STKc_SRPK1 |
| cd06637 | 2798-3051  | STKc_TNIK |
| cd14047 | 2796-3041  | STKc_EIF2AK2_PKR |
| cd05072 | 2799-2992  | PTKc_Lyn |
| cd14147 | 2835-3047  | STKc_MLK3 |
| cd13243 | 1449-1592  | PH_PLEKHG1_G2_G3 |
| cd08223 | 2796-3041  | STKc_Nek4 |
| cd13974 | 2898-3045  | STKc_SHIK |
| pfam00650 | 68-204  | CRAL_TRIO |
| cd13988 | 2802-2992  | STKc_TBK1 |
| cd05081 | 2799-2987  | PTKc_Jak3_rpt2 |
| cd14065 | 2802-2981  | PKc_LIMK_like |
| cd14218 | 2790-2988  | STKc_SRPK3 |
| cd14224 | 2802-2988  | PKc_DYRK2_3 |
| cd14203 | 2801-2992  | PTKc_Src_Fyn_like |
| cd05764 | 2699-2776  | Ig_2 |
| cd14027 | 2828-3013  | STKc_RIP1 |
| cd14019 | 2801-3046  | STKc_Cdc7 |
| cd14062 | 2905-2992  | STKc_Raf |
| cd07854 | 2794-3051  | STKc_MAPK4_6 |
| cd05069 | 2788-3040  | PTKc_Yes |
| cd14013 | 2892-3050  | STKc_SNT7_plant |
| cd05071 | 2788-2981  | PTKc_Src |
| cd07858 | 2793-2979  | STKc_TEY_MAPK |
| cd14205 | 2801-2987  | PTKc_Jak2_rpt2 |
| cd14058 | 2802-2992  | STKc_TAK1 |
| cd05068 | 2802-2987  | PTKc_Frk_like |
| cd05052 | 2802-2992  | PTKc_Abl |
| cd14150 | 2901-2992  | STKc_A-Raf |
| cd07870 | 2796-2992  | STKc_PFTAIRE2 |
| cd14213 | 2796-2979  | PKc_CLK1_4 |
| cd05084 | 2801-3047  | PTKc_Fes |
| cd14011 | 2877-3041  | PK_SCY1_like |
| cd14151 | 2802-2992  | STKc_B-Raf |
| cd06616 | 2798-3040  | PKc_MKK4 |
| cd14214 | 2796-2992  | PKc_CLK3 |
| cd13325 | 1479-1592  | PH_unc89 |
| cd05073 | 2801-2992  | PTKc_Hck |
| cd05070 | 2788-2992  | PTKc_Fyn |
| cd05080 | 2795-2993  | PTKc_Tyk2_rpt2 |
| cd01224 | 1469-1593  | PH_Collybistin_ASEF |
| cd14139 | 2798-3042  | PTKc_Wee1b |
| cd05737 | 2694-2776  | Ig_Myomesin_like_C |
| cd13992 | 2819-3043  | PK_GC |
| cd14149 | 2898-2992  | STKc_C-Raf |
| cd14036 | 2824-3047  | STKc_GAK |
| cd14023 | 2954-3050  | PK_TRB1 |
| cd05041 | 2802-2992  | PTKc_Fes_like |
| cd14048 | 2802-3041  | STKc_EIF2AK3_PERK |
| cd05048 | 2801-2999  | PTKc_Ror |
| cd07864 | 2796-3050  | STKc_CDK12 |
| pfam00435 | 908-999  | Spectrin |
| cd07842 | 2795-3049  | STKc_CDK8_like |
| cd07849 | 2791-3051  | STKc_ERK1_2_like |
| cd05730 | 2684-2776  | Ig3_NCAM-1_like |
| cd14067 | 2839-2993  | STKc_LRRK1 |
| pfam00169 | 1483-1590  | PH |
| cd07843 | 2805-3049  | STKc_CDC2L1 |
| cd14156 | 2802-2981  | PKc_LIMK_like_unk |
| cd05079 | 2795-2987  | PTKc_Jak1_rpt2 |
| cd13976 | 2848-3050  | PK_TRB |
| cd05047 | 2802-2992  | PTKc_Tie |
| smart00233 | 1483-1591  | PH |
| pfam13927 | 2684-2763  | Ig_3 |
| smart00150 | 221-337  | SPEC |
| cd05065 | 2798-3012  | PTKc_EphR_B |
| cd14138 | 2792-3041  | PTKc_Wee1a |
| cd05111 | 2802-2992  | PTK_HER3 |
| cd14215 | 2796-2992  | PKc_CLK2 |
| cd05032 | 2801-2999  | PTKc_InsR_like |
| cd14022 | 2898-3050  | PK_TRB2 |
| cd14063 | 2802-3046  | PK_KSR |
| cd00821 | 1501-1586  | PH |
| cd05085 | 2802-2992  | PTKc_Fer |
| cd05893 | 2702-2776  | Ig_Palladin_C |
| cd06617 | 2899-3066  | PKc_MKK3_6 |
| cd00174 | 1662-1712  | SH3 |
| pfam00435 | 1143-1243  | Spectrin |
| cd13977 | 2902-3041  | STKc_PDIK1L |
| cd14217 | 2790-2988  | STKc_SRPK2 |
| cd13975 | 2801-2988  | PKc_Dusty |
| smart00326 | 1662-1713  | SH3 |
| cd05891 | 2694-2766  | Ig_M-protein_C |
| cd05058 | 2802-2994  | PTKc_Met_Ron |
| smart00150 | 676-783  | SPEC |
| cd05852 | 2699-2776  | Ig5_Contactin-1 |
| cd05089 | 2802-2992  | PTKc_Tie1 |
| cd05083 | 2800-2999  | PTKc_Chk |
| cd05744 | 2702-2776  | Ig_Myotilin_C_like |
| cd14160 | 2829-3012  | PK_IRAK3 |
| cd05046 | 2797-2999  | PTK_CCK4 |
| cd11764 | 1660-1713  | SH3_Eps8 |
| pfam00435 | 341-444  | Spectrin |
| smart00233 | 2175-2270  | PH |
| pfam00435 | 571-670  | Spectrin |
| cd13239 | 2151-2275  | PH_Obscurin |
| cd13325 | 2156-2272  | PH_unc89 |
| pfam00169 | 2175-2271  | PH |
| pfam00435 | 220-338  | Spectrin |
| pfam00435 | 676-783  | Spectrin |
| cd13243 | 2126-2272  | PH_PLEKHG1_G2_G3 |
| cd11853 | 1662-1712  | SH3_Kalirin_2 |
| cd11852 | 2557-2612  | SH3_Kalirin_1 |
| cd00176 | 223-339  | SPEC |
| smart00220 | 2796-3050  | S_TKc |
| pfam07679 | 2685-2776  | I-set |
| pfam00069 | 2796-3050  | Pkinase |
| PTZ00263 | 2802-3038  | PTZ00263 |
| COG0515 | 2796-3081  | SPS1 |
| PHA03390 | 2849-3038  | pk1 |
| PLN00034 | 2796-3059  | PLN00034 |
| PTZ00266 | 2796-3048  | PTZ00266 |
| PTZ00426 | 2796-2992  | PTZ00426 |
| smart00219 | 2801-3040  | TyrKc |
| smart00221 | 2801-3040  | STYKc |
| pfam07714 | 2801-3040  | Pkinase_Tyr |
| smart00409 | 2692-2776  | IG |
| smart00410 | 2692-2776  | IG_like |
| TIGR03903 | 2818-2988  | TOMM_kin_cyc |
| PTZ00024 | 2789-3051  | PTZ00024 |
| PLN00009 | 2796-3020  | PLN00009 |
| PTZ00036 | 2802-3044  | PTZ00036 |
| PTZ00267 | 2823-3051  | PTZ00267 |
| PTZ00283 | 2898-3045  | PTZ00283 |
| PHA03247 | 2330-2540  | PHA03247 |
| PHA03212 | 2830-3045  | PHA03212 |
| smart00408 | 2699-2766  | IGc2 |
| PHA03247 | 2333-2536  | PHA03247 |
| PHA03211 | 2838-2983  | PHA03211 |
| COG5422 | 1958-2135  | ROM1 |
| PRK12323 | 2329-2537  | PRK12323 |
| PHA03247 | 2330-2496  | PHA03247 |
| PHA03307 | 2331-2533  | PHA03307 |
| pfam10667 | 2336-2507  | DUF2486 |
| PHA03209 | 2799-2995  | PHA03209 |
| PHA03307 | 2331-2533  | PHA03307 |
| PLN03225 | 2892-2962  | PLN03225 |
| COG5422 | 1280-1457  | ROM1 |
| PRK13184 | 2903-2992  | pknD |
| PHA03307 | 2330-2546  | PHA03307 |
| PHA03307 | 2331-2520  | PHA03307 |
| PHA03307 | 2330-2537  | PHA03307 |
| PHA03247 | 2331-2519  | PHA03247 |
| PHA03307 | 2330-2508  | PHA03307 |
| TIGR02168 | 733-1039  | SMC_prok_B |
| COG0419 | 393-1135  | SbcC |
| PHA03307 | 2330-2539  | PHA03307 |
| PHA03247 | 2364-2519  | PHA03247 |
| PHA03247 | 2330-2534  | PHA03247 |
| PRK12323 | 2330-2523  | PRK12323 |
| PHA03307 | 2377-2497  | PHA03307 |
| TIGR00618 | 417-973  | sbcc |
| PRK12323 | 2373-2514  | PRK12323 |
| PHA03247 | 2330-2520  | PHA03247 |
| TIGR02168 | 544-846  | SMC_prok_B |
| PHA03307 | 2334-2451  | PHA03307 |
| PHA03307 | 2368-2497  | PHA03307 |
| COG3096 | 876-1195  | MukB |
| COG1196 | 561-904  | Smc |
| COG1196 | 729-976  | Smc |
| TIGR00618 | 528-1040  | sbcc |
| TIGR02169 | 752-976  | SMC_prok_A |
Ontology Information
| HPRD ID | 6371 |    
|---|---|
| Molecular Class | Guanine nucleotide exchange factor |
| Molecular Function | Chaperone activity (GO:0003754) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165)   |
Drug Information
No matching records could be found.
External Links
| ArrayExpress | GO |    
|---|---|
| ICGC | GO |    
| Cancer3D | GO |    
| COSMIC | GO |    
| NCG | GO |    
| TSGene | GO |    
| Tumor Gene Family of Databases | GO |    
| CCDB | GO |    
| G2SBC | GO |    
| Osteosarcoma Database | GO |    
| RCDB | GO |    
