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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
TTC9 23508 Tetratricopeptide repeat domain 9  14TTC9A 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
21531130   2011Cell line : -

Source : Japanees patients

Sample Type : CRC tumor and normal tissue

No. of Sample : 113

Stage : TNM Stage I-IV

Peptide Nucleic Acid (PNA)-clamp real-timeRT-PCR TaqMan assay, Gene expression profiles.Up-regulation-113 (55 male nad 23 female with average age 65 year)patients who underwent a surgical resection of the primary CRC were included in this study.


Gene Details



Chromosome: 14; NC_000014.8 (71108504..71142077)

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Gene Type protein coding
Gene Family Tetratricopeptide (TTC) repeat domain containing
Description This gene encodes a protein that contains three tetratricopeptide repeats. The gene has been shown to be hormonally regulated in breast cancer cells and may play a role in cancer cell invasion and metastasis. [provided by RefSeq, Mar 2009]  
Chromosome 14
Location 14q24.2
Start 70641787  
End 70675360  
Strand -  
Gene Sequence

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Length 33574  
OMIM ID 610488   
HGNC ID HGNC:20267   
Unigene ID Hs.79170    
Ensembl ID ENSG00000133985   
PharmGKB ID -   

mRNA Information


mRNA ID NM_015351.1
Exon join(1..749,25778..25960,29290..33574)  
mRNA Sequence

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Length 5217  



CDS Information


   
Location join(344..749,25778..25960,29290..29369)
CDS Sequence

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CCDS ID CCDS45132.1



Protein Information


      
Protein IDNP_056166.1
Protein NameTetratricopeptide repeat domain 9
Molecular Wt. (Da)24248
Protein Sequence

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Length 222  
Uniprot IDO43909
Ensembl Protein ID ENSP00000220562  



Post-translational Modification Information (Source : HPRD)


No matching records could be found.

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

No matching records from HPRD source could be found.

Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
pfam00515165-197  TPR_1
cl22897165-197  TPR_1 superfamily
smart00028164-197  TPR
pfam07719164-197  TPR_2
TIGR02917117-213  PEP_TPR_lipo
pfam13424129-190  TPR_12


Ontology Information


   
HPRD ID613
Molecular ClassUnclassified
Molecular FunctionTransporter activity (GO:0005215)
Biological ProcessTransport (GO:0006810)  



SNP Information


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Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO