Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| TTLL3 | 26140 | tubulin tyrosine ligase-like family, member 3  | 3 | DKFZP434B103, HOTTL  |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 25180231    | 2014 | Cell line : - Source : - Sample Type : - No. of Sample : - Stage : - | - | Down-regulation | - | Decreased levels of TTLL3 expression are linked to the development of human colorectal carcinomas. |
Gene Details

| Gene Type | protein coding |
|---|---|
| Gene Family | Tubulin tyrosine ligase-like family |
| Description | -   | Chromosome | 3 |
| Location | 3p25.3 |
| Start | 9851632   |
| End | 9878040   |
| Strand | +   |
| Gene Sequence |    Download   Select all |
| Length | 26409   |
| OMIM ID | -    |
| HGNC ID | HGNC:24483    |
| Unigene ID | Hs.726435    |
| Ensembl ID | ENSG00000214021    |
| PharmGKB ID | PA134942870    |
mRNA Information
| mRNA ID | ?NM_001025930.3 |
|---|---|
| Exon |   | mRNA Sequence |    Download   Select all |
| Length |   |
CDS Information
| Location | |
|---|---|
| CDS Sequence |    Download   Select all |
| CCDS ID | - |    
Protein Information
| Protein ID | NP_001021100.3 |
|---|---|
| Protein Name | tubulin tyrosine ligase-like family, member 3 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence |    Download   Select all |
| Length | 772   |
| Uniprot ID | Q9H0A0 |    
| Ensembl Protein ID | ENSP00000257829   |    
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING)      View   
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam03133 | 213-499  | TTL |
| cl17255 | 213-499  | ATP-grasp_4 superfamily |
Ontology Information
| HPRD ID | 16646 |    
|---|---|
| Molecular Class | Enzyme: Ligase |
| Molecular Function | Transcription regulator activity (GO:0030528) |
| Biological Process | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219)   |
Drug Information
No matching records could be found.
External Links
| ArrayExpress | GO |    
|---|---|
| ICGC | GO |    
| Cancer3D | GO |    
| COSMIC | GO |    
| NCG | GO |    
| TSGene | GO |    
| Tumor Gene Family of Databases | GO |    
| CCDB | GO |    
| G2SBC | GO |    
| Osteosarcoma Database | GO |    
| RCDB | GO |    
