CoReCG

Search results:

General Information

Gene_Symbol	Gene_ID	Gene_Name	Chromosome	Alias
USH1C	10083	Usher syndrome 1C (autosomal recessive, severe)	11	PDZ73; AIE-75; DFNB18; PDZ-45; PDZ-73; PDZD7C; DFNB18A; NY-CO-37; NY-CO-38; ush1cpst; PDZ-73/NY-CO-38

Evidence
Gene
mRNA
CDS
Protein
PTM
Enzyme
PPi
Pathway
Structural
Domain
Ontology
SNP
Drug
External Links

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
15219944	2004	Cell line : SW 480 Source : - Sample Type : - No. of Sample : - Stage : -	AIE-75 transfection and cell cloning, RT-PCR assay for AIE-75 expression, Cell growth count	Unknown	-	Expression of AIE-75 causes G2/M cell cycle arrest and subsequent mitotic slippage. AIE-75 interacts with PP2AC and prevent cells to transit mitotic phase.
20089989	2010	Cell line : - Source : VU University Medical Center, Amsterdam, The Netherlands. Sample Type : CRC tumor and normal tissue No. of Sample : - Stage : TNM Stage II	Biochemical isolation to nano-LC-MS/MS analysis	Unknown	-	-

Gene Details

Chromosome: 11; NC_000011.9 (17515442..17565963, complement)
View Larger Image

Gene Type	protein coding
Gene Family	-
Description	This gene encodes a scaffold protein that functions in the assembly of Usher protein complexes. The protein contains PDZ domains, a coiled-coil region with a bipartite nuclear localization signal and a PEST degradation sequence. Defects in this gene are the cause of Usher syndrome type 1C and non-syndromic sensorineural deafness autosomal recessive type 18. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Chromosome	11
Location	11p14.3
Start	17493895
End	17544416
Strand	-
Gene Sequence	>gi\|568815587:c17544416-17493895 Homo sapiens chromosome 11, GRCh38.p2 Primary Assembly AGCTCCGAGGGCGGCTGGCCCGGTCGCGGTCGCGGCTCTTTCCAGCTCCTGGCAGCCGGGCACCCGAAGG AACGGGTCGTGCAACGACGCAGCTGGACCTGGCCCAGCCATGGACCGAAAAGTGGCCCGAGAATTCCGGC ATAAGGTCAGAGCTGCAGGGCGCCCCAGGCTTCTGGGACTCCGGAGTCCTGGGCGCGGTGGGTAGGGGGT GGACACCCCGGCACTGCCCCTCCCTTTTCCGGCCCCACCTGATGGCTCTGGTTGGGCTGGGACACCCGAG GGTCGTCTGGCTGGCAGCAGGGATCCCCAGTAAAGTGAGGGAGGGAATGCGGGGACTCCCGGCTCAAGGA CTGCTAAACGAGTCGATCTTCTGCCAGCCTTTCTCCCTCTGCCTTCCAGGGGCAGGGACGTCTCTGGGGT TTGAATTCCTTCCAGTCTTGGCCGCTTTTCTGAGGTGCCCCCTTTGTGGGCAAGCCCCTCTCCTTCCTAG TGCCCCCAGCTCAGGGCTGTTGAGGCATGTGGAGACAGTCTGGGGCAGTATCTGAGAGGTGAGGGTTGGG AGAAGGGAAACTAGACGTCTCTCTCTCTGCCTTTTGACCTCAGAACATGAGTTAGAAGCATTTCAGCCCT GCCTGCCTAAGGGCGTTTCTTAGGGTCTGAGAAGTAGCTGAGGAGCTGGTGCTGACCCGGGTGCGGTGGG GAGGAAGGGAGGAGGTACTGAGGGCGTCGGAGCTGGGCTCTGGCCGGCCAGATCCTTCAGGCAGAGCCGG GTCCACCCTGGTGTGTCCCAGTGAGGGGCCTCACTGGTGGTCTGGGATTCTCAAGGACCATCTCTGGAAG TGGCCAGGTTTCACACAGGGCATTTCGAGAATGATTCACAAAGCTGTGCAGAATCTGCTGAGGCCCTGAG ACCAGAGAGGGCCATCAAAGAGATCCAGCCTACTTCCCCACCAAGTCTTAGGATGCCTCTGAGTCTGGGG ATGAAGCCGCTTGGGGGGGGTGGGTGGTATCTGGAGCTCCCCACAGGCCCTGCCTGAGGGGCAGGTAACT ATTGATAACTTAACTATTGATAACTGTGTGACCCAAGGCTCTCCCAAAGACCCCAGGGGCAGTGTCTTTA GACCAAGCCAAACCTCTTCCTGGTTTGAGAGCTGAGCTCAGGTAGGGCAGGTCAGGGTGCTTAACTCCTT CCTTCCCATAAAGAGGCCCATAGGAGCCCAAGGAGCTAGCCAGTGTAGGGGCCACAGGGGCTTGGGGCCA AGGGCCCGGGGTCAGTTATTCATTTAATAAGCATGTTTTGAGCATCCTCTCAGCCATACCCAGTCTGTGC CCTTTGCTGGTGGTGTAGGTGGGAGGCAGACCCTACCCTGGTAATTACCCATGTCTGAGTGCTGCGTGTT GAGGCCAAGCTTTTGTAGGGGCACAAAGGGACAGCTCAAACTGGCAGAAGGCTCCTGAAAACAAGGTCTT GGGCATTTCTGGTCCTGCTCCCAGGGGTGGGTGATAGCTGGAAGTTCAGCAGGAATTTAGGGGCTGGCGA ATACCAAGGGGAGCTTGAGAGAGCATTCACTGTTACATCCTGTTGCAAAGAGACATGTCGGAAGAAATTT CAGCCACTAAGGACATTTTGTGAGTGTAGATTTCAGGCAACCCAGTTTGAAGGAGCTCAGCCTTCCATCC CCCAACCCAAGACTCAGGGTTGAATTTCAGTTTCCTGCCCCTGGCCTGAAATAACATCAGGTCTTCTGCC TTCACTCTGTGGGGTACCTGCTCTCTCTTTTTTGTGAGAATCATCTCCAGGGTCCCTGGTGTCTGATGCA GATCCTGGGTTTGCCCTGTTCCTCTTCCCCAGGTCCCACAGGCTCCAAAGGGCCTCAGACCTCCACGTTT CCTCTGCCCTACTCTTCCTCATCGCAACAGTCATTACTTATTAATATCCCTGTGTGCAGGCAGGGCAGGC GCCATGCGCTAGGCAAGGCCCAGGCTGGACTTTGTGCCCTGCTGCCTTGGAGACAGCCACAGCCTTCCCC TCCCAGGTTGGGGATCATCCAGGAACTGGGGAGAGAGGATGAAGCACAGAGGATAGAAAGGAGGCACACA GACATGCTGGGAGAAATTTACAGCTTGCTGTTGTTTGCTTTGTAGGGGTCCCTTCCTTAGTGTTTTGGAA GAAATGGTTTGTGATCTAAATCCTTAGTTGTTGGAAGTAATATTTAAGGTAGTGTGTTATAATGGAAAGT GCTCTGTGACCTTGAGCAAGTTACTTAATCTCTCTGTGCCTCAGTGCTCTTACTTGTGAAAAGAGATAAC AATATTTAACGAATAAGGTTACCATGAATGCTGAATGAGACCTACATGTGTGTGGGGAGCTTAAATAGAC CCTGGCACTTAGGGAGCTCTCAAGAAATGTCCATGTTGATTATTATCTGGAGTTAGCAGAACTGGGACCA AATCTTAGCCCTGTCACTGTCAGGAAGACCTTGACCAAGCCACCCACTCTCCCTGAGTTTTAGTTTCTTC AGCTATGAGATGGAGTTTGTAGAACTTACCTCACAAGACAGTCAAAACTAACTAGCAATTAAAGTACTGG CTGCTCTGGGCCCACAGTAACCACACTGTTTCCAGCTGATACCTGCAGAGTGTCCAGTGGGAGCCAACAG GCTCCAGGCATCGACTCCCTTTGATTTGTGAAGTTACCCCAAGGCCGCCAGGAGCACTTGCATACCCTTC CAGTAACTAGTAGCAACCTTGGGCCAGGATGTGGGGGAGCAGGGCTTGGTCAGAGACTGTTTTCTCCCTC AGAGAACCAGCTTTCAAAGGGAGACTGCTCTTCTGTTCGCAGCACCAGCACAGGGTAGGAACTTGGTTAC TCATTGGCTTAAAAGTATTTATTGCCTCTTCAGCAATCATGCATTTATGAGCATAGCTGTGTATTCTGCC TGAGGCCAGGCATCTGACAACCGGTTGGGATGAATAAGATCAGAAAGAGCCACCACTCTCTAGGAATTTG TTAATCATTCATTTATTCACATAGGCAATAAATATTGACTGAGCCCTTAATATATGCCAGGCAGTACTCT AAGCATCAAAAAACAAAATAAAGCCCTTGCTGTCTTAGACAGTACATTCCAGTAGGGAAGACAGGTAGTT AAAAGGAAATCAACAAAAGTATCATACAATGCCAGATAGTGATAAATTCTATGAAAAAATAAACTAAGAT GGGGAGAGAGAGATAGTAAGTGACAAGGTAGGCAGTCACGAAGGCCTCTCTGAAGAGGTGACATCTGAGC AGAGACCTAGAAGAAGTGAGGAGAAGGAGCCACAGAGATACATGTAGAAGAGCATTCCCTAAAGTGGAAG CAACAAGTGTGAAGGCCCTGAGGCAAGCAGATGCCCGCCTGTATGGAACAGCAAGTAGGACAGTGTGTCC CAGAGGAATCGTGAGTGGAGAATGGTGAGAAATGGGTCGGAGGGGTGGTAGGGGCCTGGTAGGCCATGGT CAGGTCAGGATTTTCTTGTAAGTGTGAATGATTTACATTTAAAAGGAATTGTTCTGGCTGCTCTGTAGAG AATCCACTGAGGGGCCCAAGAGTAGAAGGGGACCTCAGTCAGGAGGCTCCTGCAGGAGCCCAGGCCAGAG GCAGGGGCTCGGACTCGGGTGAGAATGGGTCGGATTCAGGATACATGTTAAAGGAAAAACTGACAGGCTT TGCTGATGGATTGGCTGCGAGCGTAGAAAGAGAGGCATCAAGGGTGAATCCACATTTGGTGGAGACGGAG CAGGTTGGTGGAGACGGAGCAGGAGGTGGTGGAAACCTAGCGTTCCACTTCGAATGCTGTAAGTTTGAGA CGCCTGCTAGAGGTGACTGAGAAGGCTGTAGGTCTGGCCTGGAGATAAGCATCGGTAGGTCCTTGGGGGT GTGAGTGGTATTTAAACCCCTGAGATGAATGAGGTCACTTAGAGAGACAGTGCAGATGGAGAGGAGACCT AGGACAGAGCCCGGGGTACCTCAACTTTTGGAGGAGAAGGAGCAGCAAGCGAGGAAGGAAAGCAAGGAGA AGCAGGGCGTGATTGCTGTGCCAGGCACAGGGTGAAATACTACAAACTAGCTGACATGTCAAGAGCCTCT GAAAAGATGAAGGGCACTGTCTATGTCCTTGATGGTGGTGATGCTTTCACACGTGCACATTTATCCCCAA ACTCATCAGGTTGTATACACTAAATATATACAGCGCTTTACATGTCAGGCATACCTCAATAAAGTGGTTC CAGAAAAAGAAAAGAAGTCAGGTGTGGCGGCTCACGCCTGAAATCCCAGCATTTTGGGAGGCTGAGGTGG GAGAATCACTTGAGTCCATGAGTTTGAGACCAGCCTGGGCAACATAGCGAGACCCCATCTCTACAAAAAA TACAAAAATTAGCCAGGTGTGGTGTTGTGCACCTGTAGTCCCAGCTACTTGAGAGGTTGAGGCAGGAGAA TCAATTGAGCCTGGAGGTTGAGGCTGCAGTGAGCTGTGGTCACACCACTGCACTCCAGCTTGGGTGACAG AGTAAGACCTGGTCTCAAAAAAAAAAAAAAAAAGAAAAAGAAAGAAACAGAAACAGAAAGAAAAGAAAGA GAGAGAGACAGAGACAGAGACAGAGAGAACCCTAGACAAGAAAGAAAGAAAGCAAAAGAAAAAGAAAAGA TGGATGATAAGAAAATGAGAGTCAAATAAAGCCTGGTACCACTGGGATGCACACTCTAAAGGCCTGGGAA GAAGTGTGGCTGGATCTATTCATCCCACTAACATCTACAGAGGGCCACTCGCTGCCCACTGCTGTGGATA TAGAATTTATGTCCACTTATTGTCACTTAGTTTTATGTAACAAACACAGGACTTACTACCTGCCAGGCAC TGTTCTGAACTCTTCATAATTATTAACTCATTAAATTAATACTAAAAAACAATGATTAATCTCTCATAGT GATTAAATCCCATTTTAAAAAGAGATGTTAGTCCTCATTTTACAGATAAGGAAACTGAGGCACAGAGAGG AGCAGACCCAGTTGGGGAAGGGGTTCTTTGGCTCTACCACCACACTCACAAGCCAGGCCTGTGTCTGGGC CACACACAGGCTTGTGGGGAGACAGGAGGGTAAAGGGAGAAAGTTCAGCACAGCTTGGTGAGTCCCATGG CAGAGTTGGGGACAAAGTGCTGTTGTGTGCACAGAGAAAGATGTGGCCAGCTTTGTGTGGGAGCCTAAGG AAAGACTTGGCCAAGAAGAGGCGACATTTGAAGTGAGTCTTAAAGATAGAGGAGGAGTCCACAGAGAGGA AATACTGCTGGTACCACCATTGCTAATGGCTAACCAGGGTGGCAGCAGGGAGCAGGTGGCTCGTCCAAGG GGGAAGCCAAGAAAGCTTTATGAACAGGTTCTACAGAAAAGGGCAGGATTAAATGACCCAACAAGCTGCA CCCTGGGGCCAGATGCAGGAGGCCAGCATCCCTGAAGGGGCCAGTAGAGGGAAGGTTACCAGAACAGGTG AGAACCAGGGCTGCCAAAGAGGCCCAGACAGCAGCTGCAGCCTTGGGTGGAGGAACCTGCCTAACTGTGG CCCAGCAGCCAGCCCCCAGGGACTAGGAGCCTCAGTTCCTGTCTCCCCACGCCTCTCATCTCCTGCTTGT GCCTCCCGATGGCTGAACACAGCAGAAAGCCAGAGGGGAGAGGAGCCCAGGCAGAGCCCTCTGGACAAAG GGCAGGGTGGAGAAGGCTGGAGGCATGAAAGGAAAAGATCTAGCACACATTTTGGAGACCTTGAAATGTC CCAGGCATTGTCATACGTGCTTTACACATACTCACTCATTTAATCCCCGCAACAGCCCAAAGAGACTTCA TCAAGCAGAACAACATGCATTATTTAATTTGTTCTGGCTCTCTTTCTCCCTGTTTGGCTGGGTGCACACC TAAAGTTGAATCTTCCTGAGTTGACTGTCCCATGGTTCCCCTGTGTAGCTATCCTGAAGGGCCAGTCCAT ATGGGGGAATACAGAGGGATGAGACTGGAGGGTACCACATGGCCAAACCCAGCTTTTGCCTCCAATACCC TAGACAAGGGGCCTGAAGATTGTGAGGGTGGAGATGCTCCCTGTCCCCTCCTCCCTCCCACACAGACCAA TAGCACAGTGCCAGAGAAACATCAGTCAGCAAATGCTAATCTAGGCAGGGCTGGCAGCAGGGGCAGGGGG TAGCAGGGATGATAATAGAGATCCCCAACAGCTATTTGTAGATGGTGGGCTCCTTTAGGGCTTCTGTGCT TAATATCAAGAGGGATCCAAGAAAAGGAAAGGCTTTCTAAATCTAGTCGGAGAAAGAAGACTGGTGTCTT TCCCACAGTAGGTGTTCAATAGATGTGTAATGGACAAGTGGACAACAAAGGAGTTATATTTCATAAGTGG ATACCATGTGGTAGATTGAAAAAAAGCAGAGGTTTTGGAGCCAGTAGGCATAGGTTGGGGTCTCAATTCT GTCACTTCTCTGAGCCTCTGTTTCCTCATCTGTAAAGTGGGGATGATAACGTTCACCTCAGAGGGTTGTT AGGATATTAAAGATAATACACGTAAAGTTCCTCAGGCAGTGGACAGTCAGTAGGGAGAGGCTGGCTGGGA TAAGTGAGCCAGACAGAAAGAGACTCAGGCTGGGAGGCAGGTGAGGAGGCTCCAGACTCTAGAAGAGGGG ACTTGGGCCTCATCTGAAATGAAGGCAGGATTCAGATGAGAGGAGGAAAGCTGTCCATTGTGGATAGATG GAGTCGCTGGGACCTACTTTTTTGTGATGAATTGGAAGTGAACTAAGGGGAGGCAGACCCAGAATATATG TGCTGAGGACCAGTGGAAAGGTGGTGACCCAGGCCTGGGCCAACAGGTCAGAAAGAAGGCTCTAGACTAG AGCAAATAGAGTTCACGTTTCATCAACGGACGCCACTGGGCACCGTGCGCTTGTGTGCATGACATGGTTC TGGGTTCCACAGGGAAATGAAGAACATGTTTGGAAGGAAGGGAAGAAAGGAGTGTGGGAGATTTACTGCG TGCCTAGTGCTTCGTATGTACCTGAGTACAGGGTACTGGGACAATGGTACAAAGCACCCTAGAGCAGGGG CTCCCCAAAACTGATCCTCGGGCTAGTGCTAGGCAGAATTCCAGAAGAGAGGAAACTATATAATTTTTTA ATATTGGAAAAGTAATTTGATTTGGACCACAGGGAAGACTACAAAGAAAAAGTAATTTAAGTGATGGTGG TATTGTTACTGCACGTTCAGGCTTTAGAGAAACTTCCATCTTTCTCAGCTTTCTTTCCTGGTGCCTTTTA ATGCCTGAAGAGTGAGGTGTGAGTGTGTGTTTTCACTCAGGTGTGGTCAGAGAACAAAGCAGTGCTGTTC TTTCTGAGTCTTTCTGAGATATTTCTGGGTGAGAATGATCCCTCCCTTTGCAGGATCTCCTGTGTAACCA GTTTTCAAGTTTTTGATGATCTATCACTTAGATTCATATTTAAAGAGCATTCTACACAAACCAGATCTAT TTTCCCTGTTAGCTGGTATGGTCTATAGAGAATTGTTTAAATAGACAAGTCAGACATGGCGGTAGATGGA ATGTTCTGAGTGAGGACAAGGAGATTCCAGTGTGTCAGGGGAAGGATCTGTTCCACTGCAGCTGAGTCCC ACTTGGGATGTGGTGAAGCGAGCAATGGCAGAACTGAGGACAGGGTTTGAGTGACCTAACCGGTGACAGT GGGTGGACATGAGGCCGAAGAGCTGAGCTCTGCAGCTGTCTCAGGAGACAGGTAGGATGAGACCTCTGGG AGCAGTGGTCAGTGCTGGAGGGCTGCTGACAAGGGCCAGGAGCCCGGGACCTTCAGGGACAGGCTCCTTT CCACCAAGACCATCTCCAAGTGATCTGTGCTTGGCCCAGGGAAGGGAGAAAAACAGAACCCTAGACCCTA ACATTGCAAGTTACCTTACTCTTCTACCTCAGTTTTCCACCTAATGCACAATAAACATGGTCTAAGGAGG ACAGTTCCTCACTACTGAAATCTAATGCTACAGCAAGATACATTTCTGCAAAGAGGGATAAGAGGGAACT TCAGTCCTAAGGCCTCAGTCAATAAGAGATTCTCTGTCCCATCTTCTTTCTTGTGTCACCACCCAGGGTT ATAACTAGGCTAGAAGTCTTTAGTCAGGGTGTCCTCTCTTCAGCCAAAGCAGACGTGATTTTTATGCTCC CCTTAGAAAGTACAACACTTGGGTTCAAAGAGTCATTCAAAAGATGTCCCATTTTCTCACTCATTATAGA CCAAGCCAAAAGTGTTTTCTTAACAGTGCAGAGGAGAGAGATGGGGCTTAGAGATAAGAAAGGAGTTCTT GAAAGCAAAGGGTTGGAAATTTTGGCCTAAAGGGACATTGGGAGTTATTTTCCCCTGCCAGGCCTGAGTC ACAATCAATGGTCATCGTGGCGTAGCAGAAAGAACATGGGCTTTGGAGTCAGACTTAGGTTCATATCCTA GCTCTGCTTATTAGCTGTGGGACACTGGGTGAGTTGACTTAACCTCTCTGATCCTCAGTTTCCTCAGCTG CAGCATTATGTGAGAATATTGCCCCAATGTGATAAACAAATGGAATAAAGCCCATGAAAAGCTCCTGGTG CCACCGCATGGGGCATTATGGGGACAACATCATTTCCCTTCCCCTTCTGTTCCCATGGTTACCTCCCTCC CACCTGAACCATGTGGGCATACCAGGAGGCAGGCAGATAAATTCATTCAATACTTCTTTATTGAGAGCTT ATTATGTGTTGGGCACGAGAAATTTAGAACAAAATAGATCTCATCTTTCCCCTCATGGGATTTTTCTGTC CAGCGAAGGTGACAGAGAAAACAATTCACAGAGAAAACAAACCTTAAATTACAAATTGTAGTCGATCTGT GAAGGAATTGAAACATCTCCGGGGTGCAGGAGTCGGTTCTGTCTGGGTAGGTGAGCAGGGAAGACCTCTC TGGAAAGGAGGTGGCCAGGCAGGGAAGTGGGGGAAGCAGTCCAAGCAGAGGGAACAAGCATACGCCAAGG CCCTGAGGCTGGAGAGCGTTCGGCCTGTGGGAAGAACTGAAAGGAGGACTTTGTAGCCAGGAAGACTGGT AGGAGAGGAGATTGGGCTTTGATAAGTCAAAGTAAGGAGTTTGGATTTAGGTTTGGTTTGGGGTACAAGA AACTACTGAGCAAGCAAGCAACATATCTAATTTATAAAGATATTTCTCGCCCCTGCTGCTAGGAGAGTTC ATACTCCTCCATCACAGCCCAGTGTGGGCAGCCCAGGCCTGTCTCAGGGAGGCACCCCTGCCCCACAGGC CTGAGCAGAGGGGGTGAGAGAATCCAGGCTATGTGGAGAGATGAGCTTTCAGAGGTGGTGGGTGCGAAAG GCCAGCCTCCCACCCTAAGATTTAGTACCACCCACTCAAGCAGATGCTTCCATCTCCTGTCATCTGGGAG CTCCTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTCGCTCTGTCACCCAGCCTGGAGTGCAGTGGTGCAA TCTTGGCTCACTGCAACCTCCGCCTCCCGAGTTCAAGTGATTCTCCTGCCTCAGCCTCCTAAGTAGCTGG GATTACAGGGGCATACCACTACGCCCAGCTAATTTTTGTATTTTAATAGAGACAGGGTTTTGCCATGTTA GCGAGGCTGGTCTCAAACTCCTGATCTCAGGTGATCTGCCCACCTCGGCCTCCCAAAGTGCTGGGATTAT AGGCGTGAGCCACCGCACCCAGCCCTAGCTGGGAACTCCTTGCACTGAGGTAGGGAGAAAGCAAGGGTGC CCTTTTGGAGCAGGTGGGCTGAACTTCTGTAGCAACTAAAGCCCAAGCTGTGAGTCAAGCCTCCCAAGTT ATTCTCACCTTTAATGAAATGCTCAGTCTGATTTTATAGGGAAGGAGGTACTGTCAGATCTAGGCCAGAA ATCTGCATTCTGTACCCCCTGCTCAGGCCAGAAATCCCAAGGGCTGGGCCCAGCATGTCCCCTCTGTGGT GGGACGGACAGACTGCCCCGGTCTTCCAGAACCCTTGGGATACCCACAGAAAGAGGTAACGCTGCTCTGG CCCTCTTCTGAGGACGAGTCAGTGGAGAGCATGCAGCTTCCAGCTGCAGCCTCTCTATGAAGGGCTGAGG CCCTGGGCCGGGAGGCTGGAGGAGAGAGGGACCCAGTGACCCCCCAAGCTTCCACCTTGCTCTGTTACCC GTTCTTGGGCTGAAGAGAGACCCAAAAATACAGTGTAGAGATTCACACTGAGGTAACTCAGGGAGTGGAA TTCAGGGCCTCCCGCTGGGATTGAGGTGCTAATGACACAACTCCTGAACCTGACCTTAGAGTGCCAGCCA TTGACGTCAACAAAGTTGAAATGATGTAACCTGACGCTCCCCCTGCGGGGCTTGTGCAGGGGCCTGGGGA GGGGGAAGGAGTGGCCATGAAACTGACTAGTGGACAGAACCCAGCTAAGGTCAGGACAAGACAGAGTGAA GGTCCCCTGGCACTGATGTTACAGAAGAATTCGGTGGTAAGGGGCTTCTGGAGAGTGGCATGTGCTATCT AAGCGAGTGGCCCAAATCCTTCCTGAAAGCATTTATCCGGCACTACAGCCACCATCAGGTAAGACAGTGG GCTTCTTCTGGCCATGGATGACACAGCCATGGGGGTGAGCAGCAGCACTGCCATGGCAGCGTGTCACTGT CACATGGGGATTCACATATGTACCTATGTGTGTTCATCCCCGTGTGTGCACATATTGCCCCACCTGGGGA CAAAGGGTGCCTGGCCACATCTGGAGGGGCAGCGGTACTCCTGTGGCCACGTTGGGGTGGTCTGCATAGG TCTGATGCATTGGGGTCAGAGGGGCAGCCTGGCCTGTGGCTCCTCTTCTCTCCTCACAACTCCAGCCCTG AAAAGCTGCTGGGGAGGCCCTTGGGGATGACCTCTCCTCCCTGAGGTCTGCTATGGGGGCGGGTGCTGAG CCTGGAGCTGTGATTCTGCTATTGGATTTTCCAGGTGGATTTTCTGATTGAAAATGATGCAGAGAAGGAC TATCTCTATGATGTGCTGCGAATGTACCACCAGTAAGTGTGCTGGGTCCAGCTCTTGTGGGCCACTTGGG TTCCTTTGTCTTCAGGGAGCCCTGGGATGGGTTGTTCTGAGACAGAGGAGCTCAGAGGGTGGATGCTCAC GGCTCCTGGAAATCAAATGGACATACCATTCACTCATTTCAGCAACTATTTACACAAGTACTTTGTACTT GGCTTTGTACTAGGGGCTGGGTATAGTTGTGAGCCAGACAGATTGGTCTCTGTTTTCAGGTTGCTCACAG TCTGATGGAGGAGGCTGTCTAGTAGCCAGATAGATTCTATAGAGCATGATTGTTGGGACAGAACAAGAAA TGCCAGCTGGCCACAGCCCTTGCATCAGATGTCTCCGATCACCCACTTGCTTTTTGATTCATTTTTTCTA CTTTATAAGCTCCTGCCACTGCTGGGCACTGTGCAGAATCTGGAAATGAATTAGATCCAATTTCTTTCCT TGAGTAACTTGTGGTCTGGTGAGGGGAGATGAACATACACTGCAAACACAAAGAACTCTAATATAAGTTA CATCAAATAACTGCTAAGTAGAGGTAAAAGCAGAAATGTGAAGAAAGGAGTTTTCCTTTCCAACTGCGAG GGAAGAGGAAGGACCAGGAAGGCTTGAGCAAGGCTTTGAAGGATAAGAAAGATTTGGGGCCAGGCAAGGT GGCTCATGCCTGTAATCCCAGAACTTTGAGAAGCTGAGGCAGGAGGATTGCTTGAGCCTAAGAGTTAGAG ACCAGCCTGGGCAACATGGTGAAATCCCATCTCTACAAAAAAATACAAAAAATTAGCCGGGTATGGTGGC GCGTGCCTGTAGTCCCAGCTACTTAGGAGACTGAGGTGGGAATATCACCTGAACCCAGGAGGTCAAGGCT GCAGTGAGCCATGATTGCATCAATGCACTCCAGCCTGGGCAAGACAGCAAGACCCTGTCTCAAAAAAATA ATAATAAAAGAAAAAGATTTTGGTAGGTGGAATATCTGGGAAGGGCATTCCAGAATGAGGGATCAGCATC AGCCAAAGTGTGGAGGCATGAAAGCAAGGGTGTGAATGGAGATAAGTAATCTGGGGGAGTAGGACTTGGG AGGGCACGGAGATCATAAATAGCCACAAGGCTGGAGAAGCTCCATGGGGACAGGTCATGGAGGGCCTTGA GCCTGCTGAGAAGAGTGGACTTTGTCCTCTGGGCAGTAAGGGGCCATCAAAGGGTTTTAAGCCAGGGAGT GCCTTACACTGAGAAAAGATGACGTGACAGTGAGTACATGGGCAGGCAGCTGCAGTCGAAGGTCTGAACA GCATGAGGGAGGAGGCATGTGAACTGTGGTGAGGTGAAATTGACAGAGCTTAGCAGCAGATACGAGTGGA GATGATGAGTGTGTGAGGAATTGTCAGCATCTCACACAGAGCTTTCCCCTCTGGAAAGATCCCAACAGCC GAGATAGGCAGCGCTGAGTTTGAAATCCTGGCTTCATCTCATCTGCAAAATGAGTCAACAATCCCTAGTA GACTGGTTTCCTGGGGATATTTATATAAGAGAACAAAGTCTTCTCAGGCACTGGCCCGGTGTGAAGAGCT CTGGGCTTTTCAGGAGTGGTCTACTCCATTCCTAAGCCTGGGCCCAGTGGCTGAAATGGCTTCCTCTTGG AATCCCTGGGTGCCTGAGGTCATGGCCAGGGGTGAGGCTCCAGGCATTCCCGGCATCTCCACAGGACCAT GGACGTGGCCGTGCTCGTGGGAGACCTGAAGCTGGTCATCAATGAACCCAGCCGTCTGCCTCTGTTTGAT GCCATTCGGCCGCTGATCCCACTGAAGCACCAGGTGGAATATGATCAGCTGACCCCCCGGCGCTCCAGGT GCAGAGGAAGCCACCAGGCTGGAGGCAGGGGGTGGAGAGATCACCCTGGGCGGGGCAGTGCTGGCAGCCA AGCTGCACCATCACCGACCTCTCCTGTGTGGCAGGAAGCTGAAGGAGGTGCGTCTGGACCGTCTGCACCC CGAAGGCCTCGGCCTGAGTGTGCGTGGTGGCCTGGAGTTTGGCTGTGGGCTCTTCATCTCCCACCTCATC AAAGGCGGTCAGGCAGACAGCGTCGGGCTCCAGGTGAGCAAACAGAGTCCGGGGGAGGGGGAGCGAGGGC CTCGGACCTCCTGCCTCCCCCTCATTCATCCACTAGGCTGTGTGGCACAACATGGTCACCCACTTTTCTG AGCCTTCGGGTGAAGAAGAGGCTGGCGCATCCTGATGGGTGTTCTTAGGCTCATAGAAATCAGGCCGCAG GCAATTGCCTGTTTTCTTGAGTGAAGCTGGTAACCTGGCTGCTGCCTGCTTCCAACTGCTGCCTCCTTCC AGCTGCTGCCGCTGCACTTCCCCCCACCTCCCCTACTCCCCAAGAGAGGAAGACAGTGATGCTGGCATAT GAAGTTTTGGACCTGTTGCCTTTTACCAGCAGGGGGAAAGAAAGCCTGGTGCAGTGTGATGCCGAAGAGC ATAGACTCTGAAGCAGGGTTAGCCGGGTTCAATTCTGGCTTTGCTGTTCATTAGGCTGTGTGACTTGGTG GAATGACTTAACCCTGTGCTTCAATTTCCTCATCTATAAAATGAGTTGCCGATAGTACTGTCTACCTCGT CAGGTTTTGTTAGTAAATGAATTAATAGTAGAAAGTGCTTATAGCAGGGCCTGGCATACAAATGCTGTGA GCCTGGTAAGTGAACAGAGAGAGGGAGATTTAAGAAACGCCTGGAATGTGCCAGGTCACATGCTCACAAG CAGTCCTTGCTATATGCATTGAACGGATCGTGCCCATTTTACAGAATTAATAGAGGCTCAGAGGCCAGTA AGTGGCAGAGCCAGGATTAGAAACTAACTGGGTCTCCTGACTGCCAAGCCCAGAAATCTCTCTTCAGCAA CGCAGGTGCCTCTCCTTTGGGGTCCCCACACCTCAGGGCCTGAGCAGAGATGGGCAGACCTCCAGGTCTC ACTCCTACCTGAGCCCAGGGCTGTGTTTTTGTGTGTTGAGATAAAGGAGGCCCTCCCACCATCACCAAGA GCTTCCAGCGGGTTTGTTATCAACATCCCAATCCAGGCTGCCAAGCTTGGGGCTTTCAAGGGGCTCGAAG GCTAATGGTACAAGACACTGTGGCGTAAGGGGTGGAAACAGGGAGCTGACAGACACCGCTTTGTTCTAAA TCCCTGTCTCACGGCTCCCTGGTGGTGTCTGAAATTTCAGCCCCTTCATTATTTCTTTCCTCTGCAGCAC ATTTTCCAGCTCAGAAATGCAGCCAGAGAAAACACATAATGAGCGCCTCTCTTGGCGTCAGCTGAGGCCG CCTTTTTTCCAGGGCGAGCTCTCTTAGGACAAGCAGTTCTCAATGCTGCCTCGATGACTGGGGGCGTTGG GGTATTTTAATGAGACCTACAGTTTTACCTTCCTGGCTGTTTCTCAGGCTTATGAATTATCGGCCCTTTC TCTAGCTGACGGGTTCATCTCTCCTTTGTGCCGCTGTCCCTCAGATCGTTATATCATCGTGGCCCTTGCA CAAAGGGCCCTTTGCAGGGCTCCACACAGGGCGAGACGGGGAGGAAAGTTGATCCTGCAACCTGAGCCAG GGGCTGTGTGGGAATCATTCCGACTGGGGTTCTGGGCAAATTCCCTTTAGGAATAAGACAGGGAACTTTA CTCAGAGGAGCTTCGGGAAAAATGGCTGCATCCATTGACCTGTCTGGGGTTCATGCTTCTGGGGAGATCT CATGCCTGAGGGCAACTGGAAGAAGATGCTGGAAGGCAGGGGATGAGCAGGTTCAGATACAGCCCGGCTG GGCTAAAGACCTGTGCTGATTTGACCTGTGAGGCTGGGTCCCCAGTGGTGGGCTTGGACCCTCCCACAGG ACCTAGTCCTGGGGGTCCACCCCTCTGCCCTTGTCCCCTGCTGGAGATACTTGGTTTTTGTTTTTTTTTC CCCAAGAATATCCTAACTTAACCTACATCCTCTGCCTTGCACAGGGCAGCCTGTGACATACAACTTGCTG TATATTCCAGACCTAGAAAATTATTCTGTGTGCTTTGGTTTTCCCTGTCATAACATGGACAGCTGCCTTT GTGTGGGACTTGAGGGCTCTGACAGGTGGCAAGGATCCAGAGAGGGCAGGATGCAGGGAATTGCAGCTAG GCTTGGCCGGATGCCCTTCTTTTCTACTTCCAGACACCCAAGAGACACCACTTGTCGATCAGGGAGACCT GACTTCAAATCCCACGACACTGTTTACTATTGGGGTAACCTTGAGCAAGTCACTTTACCTCTCTGAGCCT CAGTTTTCTCATCCGATTAACAGAGATACAAATTCCTGCTCTGCAGGGTTGTTGTGAAAAATAGGTGGAA GGAGTTAGTCTGGCCGCTGTCCTTGAATTACATGTTCCCAGAAACCTAGAGAGTTCTTTAGTGGGCCCCC ACCCCAGTGCCATTTTGAGCCCTTGGCCACTCCTGTCAGGTCCCTGAGAAGACTGGGGTCTGTGTCCCGG AGTGGGAGGGAAGCGTTCCTTGGAATAGTGAGAAGGTGACTCTGTGGGAATGCTGTAGAGGGCAGGAGTT GCCCTAGAGGACCCCTCGGAGGCTGCATGTCCACCCAGCCCCTACCTACCTAGACCCACAGGGAGTCCAG CTTGCATCCCTCACGTGTGCCAGCACGTCTCCAAAGGGTGAGCACGTGTGTTTCGAGTTAAGCCCCCAGC TGACCTGCACTGGCCTCAGACCGGAACCTCTCCAGGAGCCAGTCTCTGTTTTGCAGCTACTGGCTGTGTG ACCTTGGACAAAACCTCACTTCCTTGGGCTTCAGCTTCAGCTGTTATCTGAGAGTTCCTCCTGCCCTGTG GTTATTAAATGAGGAGCTCCAGAATTGATCCCCAGGGCCGGGGTGCCTGGAGGAGCCGGCAGTATCCAGC AGGGGGCAATCTCACCACGGCTCTGTATCCAGGGCTGGCTGCCCAGGGCCCATCTCAACAATCCACTGTG GCCTAAGCCCTGAGAAGAGAGATCTGAGCTGAGTATTCAGGGATCAGGACTAACTCATGATAACAATAGC AATCATGTATTGAGTGCTTACTGTGTGGCAGGCACTAGCTGTCTTTACATGCACAAGTTCACTTAATTCT CACAGCAACCTTGGTATTCCCCATTTTACAGACGAGGAAAACAGGTTCAGACAGTTCAAGAGACTTGCTC AAGGTCATATAGCTAATAATAATAAAAGAAGGGATTTGAACCCAGCACATCTGATGCCAAAGCCCTGTGC TCGTTCACTGTTCTTTGCTTGCTCCCAAAATAGGAATTCAGAGGTCAGGGCCACAGCAGAGTTAAAATGT TCATCAAGTTTCCATATGATGGGAAAAAAAAATCATATGTGTGTGTGTGTTGGTGATGTGAGCTTGGGTC AGGAGTCACAGAAGGTCCCCACCCCGACTCAGTTACAGTGTTGTAGCAATTAACAGAGATAGGGAGCCAA CTTCCTAGGGGTGGGTTGGGACAAAGTCCCGGTAAGAATAGCTTAAAGCTGAGTGAAATGTCACCCTTTG CATAGAATCCAGAATCTGATGGTGCCCCAGTGGAGTGAAAGGGGCACTAGAGTGAGGGTGCAGAGAGTTC TGAGATCTTCTCCCAGCTCTGCTGCACACCCGCTGTGCCCCTCACCCCTGTCTTGGTTTCTCCATCTGTA AAATGGGGCGACAAGACTGCTTGGACATGCCACCTGAACCTGGGATCCCCCGGGCTGATGGAGGGTGGGT TGGTTGAGATCAAGGCTTATTCCAGGGGGTGGCACAGCCACCCTTCCCTTTTCCGGAGAGCAGTCCGGGA GCATCTGGTGGTGAGTCTGCCCCACTGCCTGATGCTCCCTCCACCTGGTGCTCCCTGCCTCTCTCTGTGG TCAAGGTAGGGGACGAGATCGTCCGGATCAATGGATATTCCATCTCCTCCTGTACCCATGAGGAGGTCAT CAACCTCATTCGAACCAAGAAAACTGTGTCCATCAAAGTGAGACGTGAGTGAGGCCAGAGCAGGGCAGTA CTCCATGACGGTGGGAGGGAGGGAGGGCGGGGGAGCAGGGCAGTACTCCATGACGGTGGGAGGGAGGGAG GGCGGGGGAGCAGGTCAGTACTCCATGACGGTGGGAGGGAGGGAGGGCGGGGGAGCTGTCCTAACCCCTG TGCCTTTCTCCCGCAGACATCGGCCTGATCCCCGTGAAAAGGTGAGAGGCCCCTCCTCTGCAGGCCAACT CTTCCCTGTGGGCCCAGGATCCTGGTACAGCCCTGGGGTCCGGCTCCCACCATGCCAGCCCTGCTTCTGG GCCAGTGGAGGCTGGAGGCTCTAGACATGGTGGATCTGGATGTGGGGCCTGGTTCCTCAAACGTCTCTCG CTAACCACCCTCCCATCTATTTTCCCTTCCCATCAGCTCTCCTGATGAGCCCCTCACTTGGCAGTATGTG GATCAGTTTGTGTCGGAATCTGGGGTAAGGGCCAGACCTCCTGTGATGGGGTTTGGGTGGGGTCATCTTC AAGGAGGGGTGGCCGGTCCTGAAGGGAGGGCTTGCTCTAGAGATGCACCCTCAGGGGCTTCACACAGGCT CCCAGGGCAGCCAGCACACCGCTGTGGGGCAGCAGCCCTCGGCCAGGCCCAGCTGGTGCAGACACATCCC CAGGGACGGAATGATGATCTGGCTGGCGTGAGTTCAGCAGTGCTCGCCCTGCAGATCCCACAAGCTCAAG AGGCCGCTTGCACGCATGTGGACACTCCGTGATTCTGCTTCTATCTCTCTTTCAGGGCGTGCGAGGCAGC CTGGGCTCCCCTGGAAATCGGGAAAACAAGGAGAAGAAGGTCTTCATCAGCCTGGTAGGCTCCCGAGGCC TTGGCTGCAGGTGGGTGGCAGGCATGCCCTGGGGTCATTCGTGGCCAGTGCACCCCAGCAGGCCCCTATT GCCCTCCCCTTCCTCACTGCCACTTCCGAGGAAACCTTGCCCACCAGGGGTGTGACTGTCCATGGGTGAT GATACTTTTTTTGTTAGATACAGGGTCTGACTCTGTTGCCCAGGCTGGAGTGCAGTGGCATGATCATAGC TCACTGTAGCCTCAACCTCCCCAGCTCAAGCAATCCTCCCACCTCAGCCTCCTGAGTAGCTGGATCTACA GGAACACACTGCCATACCCAGCTAACTTTTAATTTTTTTGTAGAGATGGAGTTTTGTTATGTTGCCCAGG CTGGTCTCAAACTCCTGGGCTCAAGTGATCCTCCCACCTCAGCCTCCCAAAGCCCTGGGATTAGAGGCAT GAAGCACCGCACCCAGCCTTGGTGTTGACACTTCTTGGTGCCTGATTTCCCCTCTGAACTTCATGACAGG CCTTTAGGGCCAGAGGGTCATCTCTAACAGAGCCCAATTTACAGATGAGGAAATTGAGGCCCAGAGGCAG AACAGTGTTACCTTGTGGGCCCTTGAGTCACTGCAAAAGGAGCCTGTTTGGCTGGTCATCTCTGTCACAG CTCTCTTGTCACTTATTAACTTGTTGGCTTCCTTAAGAGGCAGACAGGGAATTCCGAACAGACACTGGGC CACACGGGGCTTAAGCATGCAGGTGCCACCGTTACTCAGATCCCAGTTCCAGCCCTGCTTTCCCACTTAA GAGCTCTGGAACCTTGGGCCAGTTACTTAACCACTTTGAGCCTCAGTTTCTCCCTCTATAAATGGGCGAT AATAATTCCCACATCACAGGGTGGTTGTGGAGAAAGTAAAGTGCCAAACTTAGTACCTGCTAAATAGTAA GCAGTTGGTAAATATTAGCTATTATTATTTAAGTTATCCCTGTTCTTTCCTTTCATTCACATTTATTCAA TGTTTTGTGCCAAGCACAAGTGATAAAAAGTCCCACCTTTCTGGGAGACAACAGCCTAATCTAGAAGCCA ACCAAGTAAATAGTTATAATATAGGGTGATAGGGACTCGAACGGGACTACATTCTGCGTCCAGGATGGCA AATAGGTGCCATCTCTAGTCAATGAGTAGCAGCTCCCTGGAGTGCTGCTTTGAAAAGCATTCTAAAGCTG TATCCAGGATTGTGGGAAAGAGTGCTGTGATCAATGAGTGACTTCTGCCACCAATCTAGGAAGGAATACT AACAGTACATGTACCATCCTTGCCGTAAATGTCATAGGAGCACTGAGAACAGAGCGGCTAGTTTAGTCTT GGGATAGAATAAGGGATCTGAGCCAGGCATGGTGGTGCACACCTGTAGTCGCAGCTAGGCTGAGGTGGGA AGATTGCTTGATCCCAGGAGTTGGAGGTTGCAGAGAGCTATGATCACACCACTGCACTCCAACCTGGGTG ACAGAGCAAGACCCTGTCTCTAAAAAATAAATTTAAAAAAATAAGAGGATCTGGTAAAAACCTTATAGAA GGGATAGCATTTGAGTCTTAATGGATGGACAGGAAAGTGCTAGAAAGAAAGAAGAAACAGCATATGAGGT ATATTAGGTGAGAGGTTGGGTAGGAAGAATTACAAGGATTTTTCTGTGGCTGTTGCCCAGGGTAGCAGTA GAAATCAGGCTGGAGAGGGACACAGAGGCTGAAGAGGTAGGCAGTCAAGGGCCTTCAGTCCTCAGCTCAT GAGTGACCTGTATCCTGAGCACTGGACATGGGTTACCTGAATCCCGAGCACACATTTCCCACCTCCCGCA GCATTTCCAGCGGCCCCATCCAGAAGCCTGGCATCTTTATCAGCCATGTGAAACCTGGCTCCCTGTCTGC TGAGGTGGGATTGGAGGTGAGTGACGCTGGGCCGGCCCCAGTGGGGGCCCACTGGAAATTGGGTCAGACT GTGATCCCGCGGTGACAGGGGCAGGTGCCTTTCCACATGGCCCTCTTTCAGTGGACACTGAGGGAGTAGG AGCCCTACCCACCCTGCAGAGAAGGCTTCACAGACTGGGGATGTTTGACCCTTCTGCAGCCTTCCCCAGC TCTGATAGTTGTTGGTCACGAGCTTGGGAATGTCGTAATGGTAATCAAAGAGCGGACCTTCAGTGTCCAC TTGCATCAGACATTGTTCCATGCCCTTTACACTTCACAAGAATGCTGAGGGTTAAGTACCACCATTATCC CCACTTTACATATGAGGAAACTGAGACCCAGAGAAAGTATATGATTTTTCCAAAATCGTGTACCTCATAT GGTAGGGCTGGGATTCAAACCTAGGTGGTCCAATCCCAAAGCAGGAACCCTTAACCTCTTCTTTGGACAA GTTACTTCATGTCTGTTTGCTTACCTGTAAGATGGGGATAATACAGGCTTTCTTCCAAGGTTGTTGTGTG GGTTAAAGTAATTAATATGTATACTAGAGCTGTGCCAAGCACATTGTAAGTGATCAGTGAATGTTAGCTA TTCTGTTATGACGATTCAACACAGCCTGTGCTAAATGAGAAGCTCAAAGGTTCCCGCATCTGCAAACTGT GATTTTTAAAGCAAATGTCATCAAATTTAGCCAAAGAAATGAACATGTAATGGTATAATATTTGATAGTT GATAAGATAGTTATGAAGTAGGGGAGTGCCAGGGTCAGCTTTAAGCCCTCCCAGAGCTCCACCAGAGCTT TCCAACTGCTCCATTCATCAGGAGGAGCTGAGGTACTGCCACTTGAAGATCCAGCATCTGACCCAGAGCC CCTGGGGGAGCCTGTCCTGCAGATGAGCGAGTGTACAGATAGCGCAAACACACTAATCTTTCTCCATTTC CCCACCAGATAGGGGACCAGATTGTCGAAGTCAATGGCGTCGACTTCTCTAACCTGGATCACAAGGAGGT GAGATGTGGGGGTCTTCACCTGTTGGCCCTTGTCATCTCCACACCCCACTTCTCATCCCCACCACCCTGG AGCCTGGGGCCTTCTGTGCTCTCTGCCTGGACTGCTGTGGTCTGTCAGGCCTCGGCCCACTGTCCTTCTG TCCCCACAGGCTGTAAATGTGCTGAAGAGTAGCCGCAGCCTGACCATCTCCATTGTAGCTGCAGCTGTAA GTCCAGAATGAGCTGGTGGGAGCCCCTTGACCTTCATCCCCAGCCCCTCTGACCTTTGATCTCTGCCACA CACTCCCAGGGTGGCTGGTCTCCTTCCCTGAAGCTCTGACAGAGCAGAGCGAGAGGACTTCTGCCCAGCA AGAAGTTTGGGTCAGGGATTGCGGGAGCCGCAGTGCCTGATGGTGCTGAGAAGACCACCTGCATCTCGGC CCCCAGGGGTGTGTCAGGGGATCCCCAGGTTCCCCGGGGGCTGAGCAAGGGGCCTCTTTTCTCCCATGAG GGCCGGGAGCTGTTCATGACAGACCGGGAGCGGCTGGCAGAGGCGCGGCAGCGTGAGCTGCAGCGGCAGG AGCTTCTCATGCAGAAGCGGCTGGCGATGGAGTCCAACAAGATCCTCCAGGAGCAGCAGGAGATGGAGCG GCAGTGAGTGCAGCCAGCCCTGGATGCCCTGTCCCGCCTCCCACCCCACCACACGACCCCACCTAGCTTG CTTCCTGCCCGCTGTGTCCCCAGCCAACTTCCTCCTCCTCCCTGGAGGCCAGTCCTCAGACCAGATGAGT TTGGTGGTAGGTCAGCGTATCCATCCTTGGCCTCAGACCACCTGGCTCCTTCCTCCTTGCTGAGCAGAGC CCCCTGTCTTCCAACATTCCAAGAATATGGAAAATAAGCATCCTACTAGCAGTAGGCTCTAGCTAGCTAG GATTAGCTACCAGCTAACATTTGTCAAGTACCTCCATAAGGCTGGTGTTGTATTAGGGCCTTGTTTATGT TTCTTAATTCCCACAATAGCCCTGGGAGGTAGAGAGTATTAACCCCATTTTAGAGGTGTGGAGACTGACA CTCAGAGAGGTGAAGCCACTTGTGTCTAACGTCACACGTGGCCAAGCTGGGATCACCCCCAGGCAATCTG GCAAGTCCCCACAGGGCTGCCCTGCCTATAGTGATGAAGCTCACCCTTGTCCAGGAGGATTGAAATGATG GCCTAAGAGAATAAATGGGGTGAGCAATTCATAAATCAAAAACTACTGTCAAGATCCAAATCCAAATACC TTTTAGGCATTTAAAAGTATTTCATGGCTGGACGCAGTGACTCACGCCTGTTATCCCAGCACTTTGGAGG TCGAGGCCGGCAGATCATCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAGCATGGTGAAACTGTGTCTC TACTAAAAATACAAAAAAAAATTAGCTGGGCATAGTGGCATGCGACTGTAATCCCAGCTTCTCGGGAGGC TGAGACATGAGAATCACTTGAACCTGGGAGGCAGAGGTTGCAGTGAGCTGATATCGCACCACTGAACTCC TGGGTGCAAAGTGAGACTTTGTCTCAATCAATCAATCAATTAATGTATTTTGAAAAGGAAAGAGGAAAGG CTGTCCCCATCTCCCCCAACACAGAGTTAGCTGGGAGTATTCCACCTGGCTAGGAGCCCCTGCTTTGCTC CTGGGGTCAGTCCAGGCCCCGCCTGTCATCAGTCACCTTACCTAAGTGTTTGGAGGAGGGTGCATGGAGT GTGGCCTTCACATGGATCTGCTTCCCTCCTCCCACAGCCCAGCATCTCTGCTCAGCCATGCCAGACAAAA CCACGCAAGAGCACAGCGTCCAGACTTTGTTAGATAACGTCCCCCAAAACCAAAGCTGGTCCAGGCCTCC TAGGAAGGGAGCCTGGAGAAAAATCCAACTTTTCTCCAAATCAAGAATTCACAGTAAGGAAGAGTTCATT TCTCTTGCATAGGGCCAAACATGCCAATCTGCATTTGTGTTTCAGAAGGAGAAAAGAAATTGCCCAGAAG GCAGCAGAGGAAAATGAGAGATACCGGAAGGAGATGGAACAGTGAGTACCTCGGCTCCACGCGTGTCTGT GCATGAACATCAGTGTGCTCAGGGGAGTGTGGCCAACCAGAGGCTGCCTCCAGAACCAGTTTACCTGGTT CTCTCATCCCCTGGTGGGTCCTCCTTTATTTGTAGTAAAGCCTGTCATATTATAGTAACTGAAACATAGT CTCGTATAATTGCCAAGGTGGGGTTCACACTCAATTTAGAATACAAGCTCGGGGACTTTGCTTGATTCAT CATGACTAGAACCATGAGGCTTCTCCCCAGGCTGGCTGGGGCTCTCCGATATGCAGGAGATGGGCCTATG GGGGTTCTGACTCCAGTAACAGGCATGGGGGTCTCATTTTAGGATTGTAGAGGAGGAAGAGAAGTTTAAG AAGCAATGGGAAGAAGACTGGGGCTCAAAGGAACAGCTACTCTTGCCTAAAACCATCACTGCTGAGGTAC ACCCAGTACCCCTTCGCAAGCCAAAGTGTAAGTTTCATGAGCCGAGGGGAGAGGCTAAGGGAACTAGTCA GAAATGCTGGCCCTCCCTCCCCTCACCACCACCTCCTAGATGGATAGCCCTTGGTGCTCTGGGCTGTGGT TCCTTCATGGAGGGGCAGCTGTGGGTCAGAGACCATCTGCCCCAGCATCGAGGTAGGAGGGATCTGTCTG CTCCCCTTGTTCACGGGCCAGCTCCACATACCCAGCTCCCAGGTCCCCCACAACACTGACATGGGCAGGC TGTCAGGCTGCTGAAGAGGGAATAAGGGCCATAGTGAAAGTGGATTAGCTCATGGGATTACCGTCCTAAT GTTTTGGGTACCATGTCCTCCTCCTACTTGGTTCTGAACAGGGGCTGGGGTGAAGCCAGCAGCAGAAAAG AGGGGAAGGACCTCACATCAGAGAAGGGCTCTGGTGGTCCAAGGTTGATTCATAACTGTGGGAGGAGCTT ACTAAGTGTCTCCAGCCCCTATATCCCTGTATGTGGACCAAGGATGGAGGCAGGAACAGGACAAGGAGGC CTCTCCCAGACACCCAGCTATGGGCTGTGGCTGTGCTGTCCTGGGGCCTCAGCTCATACTCTCCTTACCA TCTCCTCTCTTCATCCGTCCCACATCCTCACCTCCATTTTCAGTCTAAGCCTCTACCACCTGCTCCCTGA CCACCTTCTCAACCCCAGCTTCCATATGCCTCTTTAAGAGGCAGCCCACACTGCCAGAGGAAAACGGGGA CCATGACAACCACAAGTCCAGGATTGCTGGTTGGGTCCTTACTCCTGCCTTCCAGCTGTTTTGACTTATA GTTGACACAGGACAGGTCCTACTCCAGCTGATTGTGCTCAGCTGACCTGGGAACCTCCAGCAAGGGGCTA TTCTGGACTCAAGAGCCCAGGTTCCCCATCTCTGCTGTGGGGCAGTCATTTGGCATGTTGTGATGGGGTC TGGACAGCTCTGTCCCCAACTTTGGGTCACATATGAGACCTATGGGAATGTCAACCTGCCAACATAGGCC ACTTGCACCAAGGAAGAGGTGCAGGGCATCTGGATGGTTCCATTTCACCCCTCCCTGGTGCAGTCAAACA GCTCCCAACACATTTCTTCCTGGCAGCAGGGCAGTGTCATCTCCTGGTCCTCTCAGAAGGACAAAGCACA CTCTCATCAGCCTCCCCCGTGACATTCAGTATCAGTTGAGGATATGGCCAGAGCTAAGATCCCAATGAAT GATCGCTGTTTTAGACAGACAGCTAATTTGCTCTTACGAGTGAAATAGGAGCTTCAGGAGAGAAATCGAT TTTAATTGCTTCTCATGGAAGTAATCCTAGTCAATTTGGTACCTTCCAAGAAATTGGGCCTCAGCTTCAC AGCAAACACACCCTCTCAGGAGCAATAGAAAATAAAAACCCTTTCACTAGCTGGTTATTTATTTAGTGCC TTTTAAACAAATCAAGCTCTTTGAATAAAAAGACCAAGAATTTTGCATTTGCTCAAGGTAAATGTGATCT TAGGCAGCTCCACAAAGCACAGGATGGATGACCCCCGCCTGCCCGCTGAGCTGGGACAGCTGCTGCCTCT ATCTGTCTCTGTATGCACCAGCAATTTAATTCTCATTTGGACCTAAGGCAGGAAATGCAGTGAGGTCCCT GAGCCAGCTCACCTCCTGCCTCACTCCCTGTTCCCCGGGGTCTAGCATGGTCAGGGCTGAGTTGGTCCAG CAGGCCTGGGCCCCAGCCAGCTCCTATCCAACCACCCTTCAACTCAGCACCCAGTTTGCAATAGGTTATA CCTGACTCAGGCTTCTATGCCTGCAAGGGGTGGGCCCTGCTTTTTTTTTTTTCTTGAGACAGAGTTTTGC TCTTGTTGCCCAGGCTGGAGTGCCATGGCGTGATCTCAGCTCCCCGCAGCCTCCGCCTCCTGGGTTCAAG CAATTCTCCTGCCTCAAAGCCTCCCGAGTAGCTGGGACTACAGGCATGCGCCACCAAGCCCAGCTAATTT TGTATTTTTGGTAGAGACAGGGTTTCACTATGTTGGTCAGGCAGGTCTTGAACTCCCAGCCTCAGGTGAT CTGCCCGTCTCCACCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACTGTGCCTGGCCCCGGGCCCTGC ATTTTTTAAAATAAAAGAGCATGGGGCATCTCTTACCTAGAAAATGAAGTCACTCATCCTAATTATGTGC CTGGGACTGACTGCCCCCCAACCTGCCCCAGGGGGCCCTTAAAATTGCTCCTGCCCACCTACCCGTGGCT GATCCAGCAGACCCCCAACATTTTGCCAAGCCCTGAAGGCCAGGACACCACCACAGAGGCTCCTAACAGA CCTTCCCTTAGCTTAGGCAGGAGTTATGTAGGTGGTTATGCAGGAGTTGCCAGGGGCAGCCTTGACTAAG GATCTGGTAGCTGAAGGATTCTTGAAAGATGGAGATGTTTAAATAGGACATCTCCAACCTTCTCTCCCTA TCCAAGGCCCCATCAACTATCTCCCCCACCTCCACCACAAGAGACCCCACGATTTGGAAGTTGAGGTTAT TTTCCTACCGAACTATTAAATAATCATTTGTGTTCCATTGTTTTATTAAGTAGTCCTTGTTAGTAAGGGA GCATCAGGGTTCCACTGTTGGGTAAATGTAATTTGAGCCAAGAGCCAAAGAACTTAACAGCCTTTGCATA GGCCAATGGGCAAGTTCTGTTAAGCTTTTAAAATATTAAAAAGCAGCTCACAAGCAAACGGGTATACTAC CTTCCAGAGTCCTAGGGAGGCCGGAGGCCAGAGTCCAAGCTGGAAACTCTGGAATGGAGGGTTTGCTCTT CTCTCCACATTATGTCAAAATTCAGGTCTTCCTAACTGCATGTACCCCTTTTACCTTTTGGGATGTCCCC ACCTCCTCAGGACCTTCAGCCTCCATCTGCTGCCCACACTGTTCAGACATCCCCTAGGGTCCCAGAGCTC CAAGGCAAGGGTGATAAGCACAAGGCTGGAGGGTCTGTTCTCCCATTGCAGCCCCTTGCCCTCAAACGTG TGCGATTCTCAGATATTCCCATCCTCCTCACTGCACTTCCCAGCCTTCAGCCCAATACCCTACAAAATGG TTCTCATGCTACCCTCAGATCTGAGTTTCCTGTTGTTAGCCCTTTGTACAGACAGAAAAACTAAAGCTGC CAAGGTTGAAAACACTGTATGCACCAGCTCAGAGCAAAAAACCTTTGCTCTGCTCTCCTGAACTCTGTCC CCTGCCCCTGACCTCACAGCTCCCATGGAGGAAGCTGATTACAGGTCCCCAAACTCCTGAGAAGGTTCTC CGGCCTCTTGGGCTCCCAAGTCCCTTTTGGTTCACCAGCTTCCTCCTCTTTTCCCTGGGTAGATGATCAG GGAGTGGAACCTGAGCTCGAGCCCGCAGATGACCTGGATGGAGGCACGGAGGAGCAGGGAGAGCAGGTTC GCGTCCCCGCTTTGCTCCCTGGCCTGGCTGCTCTGCTTTACCCTGCCCGCCTCCTCCTGACCGCAGTGCA GACACCCAGCTTCAGGGGCCCAGCATGTGTGGGGGCCAATAGAGTCTGTAAAGCTCCTCCAAGCCCCAGC TTGGCCCAAGCACTGTACACAAAGCCTAGACGACAGGACTCAATGCCCAGGCTGGTAGATCAGCTGTTGC ACACTGGTACCACTGAACCGCTGGCTCGAATATTTAGATATTGCCAAATTCCCCCTCTGCTGCTCTGGCC CCTCCCCCAGGACCCCCTAGACCACTCTCAAATCCAGCAACTGAGGAGGTAGTGTCTGGTCCAGCAGGAG GCTTTCAGCATCCTGTTCCAGCACTCAGGCTGGTCCGGGGTGGGTAATTCAGCCATCGCTCTTGGCCCCA GGGAGCTTCAGATTGGGGGTATTACTCTGTGGAGCTGCGGCCTGGGGAAGGAAGGGGGCTGGTGCACTGG CTATCTGGCCTGGATGAGGATCTGTTTTCTGGGGGCACATCTCCTGCCCGCTCCTGCTGGAGCTGTCCTT CCAAGAGCTGTCCCAGCCACTGCCTTCTCTTTGAATGTTGAAAGCGGAGGACTTGACCTGCACTATGAGA CAAGCCAGTTTTGTTCTGTCGAACAACAGTTCTAGGCAGACACCCAGGCTCCCTTTTGTCTCGAGCCATT TTTTGTATGGAGGGACCAGACATGGGTTAGAAAAGGCCTTGTTCTCTTTCAACAAGGCTTTGTATGTGAA GACTGTGATTTGGAAAAGCTCATCCTTCCACAAGGGGTTTTCTCTTTGATGTTCTGGCCCTGACTTCTGA AACCAGTGTTCTGGGGAGAGGCATTTGAGAGTGACCCAGGGCCTGGGAACCGGGGCTTTTCTCGGTGGTC TTAGGCCTGTTCTGCAACCAAGGCAAGGCCAGGTAAGCCGAGTTGGACAGAGGGTGCAGTTTTGCTGTCG GATCTGCCAATGCTGTTTATCTCACAAAGTCATGCATTCCTTGGGAACCCAGCTCCCATCTGCTGCCCAT GGATGCTCTGGCTGAGCTGAACTGTGTCTCATCATTTTGTTATCTGTGTCTTATAGCTTTTGGATGGTTT TATCGTTACGATGGCAAATTCCCAACCATCCGGAAGGTAGGACAGGGTTGGGTGCTGTGCTGGTGTGCTG CTTAGTTTGCTGTGGGTTTTGGCTTTTCCCAAACATTCCTTGTCCTATCAACACTAAATGGTGTGACTTG GCCTGTTCACTTGGAAGGCTAACTCCATCTCCATCTTTGTGTCAGGCTGACATCAAATGGCAGGGTGCTG TTGCAAAGGCAACATTGGGAGAGGGATCCATGGTGTGAGACCTATCCAAGTACCATCTGGCAGTGTGTGC ATCAGCACTGGCCCTGATGGGAACAGGAAAGGGGCAGGAAGCTTCTCCTGTGTTTCTCTGTCAAGTAGAA CTAGAGACCAAGGCCAGAAGCTTGGGGTCAGACAGAGCAAATTATCGGAGTGGGTGTACCTAGTGCATGT TATGAGACCAGCTGTGCCAGACGCAGCCTGGCTGACGAGGTGGGGATTTGCTGCCTCAGGTTGGGACAGA GACCCACTCCAAGCACAGCCCTCTCCTAGGAATATCTCTGCATGTGCCCAGGATAATGCATTTTTCCAAT TTCTAGGACCTTTAATTTTCTCTCTAAATCTTATTACAATATCTCCAGGCCTTGTAAAACTCTCTTGTCC TTATCTTTCTAAATCACATTGACATTTGATTGTGAAAACATTGCTGTTAATATCTATAATTGGACATTCG AGATGACTTGGTATTTGGAGGTCAGGCAGCAGCATAAATCTGGGTGAGCTAAATTGGATGTTATCACTTG ACCAGCGCTTTCTGGCAAGATGTCAGTCCCCCAGAAACCAGAGCACTGGCAGCTGAGTGACCTTGATGAT ATATAATTCTCCCTGCCTGTAAAATGGGAATATTAACTGTGCCAGGAAAATCTACCCCCTTCCTCCAGCA CATTGCTATTAAAATAACAAACAGTAATATTTTTCCTGACAGAGGTTAATGCCTTTATCTAGGAACATCT ATCAGGATTTGTATAGCATTGAATAAACTTGGAACAGAGTTCCTCTGGGAATTCCTTCACACATTGTCCT GGTCTCAGAAAGGCCTTGGTCTCATAAGACTATCTGTTTCCCTTGACAGGCTGACTTTGGTGGCTTAGGA TGCCTCATTGGGTTAGATTTCTAATTCTTCTCTATATTCTGCCTCTACTAGAACTCAGCTAGAGAGGACA AAACACACACACACACACACAAGCACACACACACATGCACACATAGGATTTTACTTGAAAAAAATAATAA AGGAGACAGATATGTCAAATCTTTTTCAGGCACTAATAACATGTAAATGTAAAAGAACTAGAATCTTCTC CACATACCACCTCCCATCAGAAATCATGTCCTTGAAAGTGCTGTTGATAAAGAAATAGGGTTGCCTTTCC CCTATTCCTTAATCTAATTATTCCAGAAACAGCTGTCATTTTGGTTTTCATTTTCACTTCAAAAAAAAAA AAAAAAAAAGAATTGCTTCTGGGTAGAATCAATAGCACAATCGCCCCATCTGCCTCACCTCTCAGTCTGG ACCAAAAGGAATATTGTAACTGACAGGCCATGGATGTAACTGACAGCTGAAAGGACAACAGAACCATGCC CCTCATACTGGCTCTGAAAACCCGTCATCATTTTTTCTAGAGCCGTGAGAGACTCTTTGTCTCCCAGCAG CTGGAACGCCAAGTCTCCAGGAAATGCAAGTGGGTATCCATGGCCATGATATCTGTGCATAAATTCCCCT TATTTAAAAATATAAAGATTCAGCTCATGTCTATAATGCCAGCACTGTGGGAGGCCAAGACAGGCGAATC ACGTGAGGTTGGGAGTTCAAGACCAGCCTGGCCAACAGGGTGAAACCCTGTCTCTATTAAAAATTCAAAA ATTAGCTGGGTGTGGTGGCGCATGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCACTTG AACCCTAGAGGCAGAGGCTGCAGTGAGCCGAGATTGCACCACTGCACTCCAGCCTGGGTGACAGAGCAGG ACCCTGTCTCAAGAAAATAATAATAATAATATAAAGATTCAGTGTCTTCTATTTCCACCTTGGCAGTAAA TCCCTCTGGGGCTCAAGGTTCCCAGGCCTTTGGCCCCACAGAATTTGTGCCAGGGCATGAAGGATTCATG ATTCTGACTAAGCCCTTTCATCAGAATTGCTTGAGTCACTCACACAGACCAGCCCTACTTGCAGGAGCCC ACCGTCTGGCAGGGAAGGCAGATTCACACACAGCTAAGTAACCTGTGTGGGGCCAGTCTGAGATCAGTGG GAAATGCCATGGGGCAACTTGCCCTCTGCATCTGTACAGATATGACTTTCTTGGGCATGAGACAGAAACT GTCTACTACCCCACCCAGAAGCCCTGACTCTATAATCTTAGCACTGGTAGTTTTTTTTTTCTTTCTTTCT TTCTTTTTTTAAGCAACAGAATGGCCATTATTCTCGTGGTGGTCCTGGAGGAGGCCAGGCTCTTACTCTA GCAAGCTACCATTAGGCAGTGTTTCTGGCTCCTCTTGGGAAATTGCTGTCTGAATCTCTACTACGATGGC AGGGATTCATCTATCAACTGAGTCTAGTGAACAAGGTAGGCAAGGAACCAAGCAGGACTCTGAAGCAGTG AGAACCATTTTCTCGAGAGGCTCATACACTGCTCTGGAGGTGGGTCCCAGAGGTGACCATTTCCAGAGCA CATTAGCAGTACACAGAGGTGTGTGTCTTTAGGAGAGGAGCTAGGAAGAGTCCCTCAGAGGTCCATAATG GCCCACCAAGTCCCTCCAGCTGTGGATGAATGTTGTGTGTCCATTGCTAGGGAGCTCAATTCCTTATTCC TGGCCTTGGATACTAAGATGATTCAGAAAATTCAAGAGCAGATCCCCAGAAGGCTTGTTGGGGGCGGGGG TGAGCTCAGTGAACAGGGGGTTTCCTCCTTGCCCCAGAAATTGCCCAGGGTGTGGGCTGTCTCTGCTGCC CCTCTCCTGAATGCTCGCTCTGTCCTCCACGCTGTGTGTGATAGGGGCTGACCCTCCCTCCTGCCGTGTT TCCCTTGCCCCCAGCTCATCAGGGCACCATAGAAAAACTAGGACCTCGAAGACTCAGGTCCAAATCCTGG TACTATCAGTTACAAGATGTCTGACATTGAACAAGGGACTTTACCTCTCTGAGCCTCAGCTCCTTCATCA AAGAATGAGGATAAACCTACATAGGAGATCATTGGTATAAATCCCTTGGCACATAGGCAGTTCATAAATG ATCATTCTCTTCCTGCCTTAGCCCCTGGCTTCCCTGCAACCCCATGAGAGAAGCAGCCAGGAATGCAGGC TCGGTGGGTCTAATTCCTACAGGAAAAATAAGGAGTCTATTTGCCTTTCATGTCCCTCCCCAAATCCTCT AGAACCCTGATGGTGAGTGTAAAGCAGTTAAGCCATTCTCTCCATGCCCTGCCTCCCAGTCCTGCAGTTT CCAGCTAGCCCTCGGTAGAGGGGCACAATTCAGAGGAAACTGTGGGTCTAGACTCTCCAGGGTGAAATGG TCCAGAGCTTAAGCATGCGGGTAAAATCTGATGTCCCTGGGTCTGAGCCCCCAGGTCTCAGTGTGACTCC TATCACTTCTAGCTTAGGACGGGACCTCTACAGATGAAGCTTGCCAGCCCTCCCAGATTTTCTCTGGAAT CTCCCAGGATGCATCTCTGAATCTGAACATGAGATGATGCAGAAGGCATGTGCCAGATACTGGAAAATCA GCACAATGCCCTTTATTTATATGGCACTTATTTATTTTTTTATTTTATTTTTTATTTATACAGAACTTTT ACAAAGTTCTTTCATGGATGTTATTTCATTGGCACTGGGTGGCAAGCCTGTGGGGGAGGTATTTTTACCA TTTTGGAGATGAGGCAAATCAGGCCCAGAGAGGTTAAGGAACTTAGCCAAGGCCACACAGCTAGTTAGTG AACTAATAAGCCAGTCTTTCTGGCTGGTAAAGAGAATGTGTCTCCCACTCTGCAGTAGGTAGCAGTGGCC TTCCTGTCCTAAACCTGAGGTCTGATGTCCAGAGTGGTGAGAGAGCTGGGGGAGGGGCTCACCATGGGAT GGTTGTGTTATGTGAGGACTGGATGCCCCGTGTGCTGTGCTGTCGACACTATTTCTAACCTTTGTCATAT AAACAATGCCACATCTACTCAGAAAGGAAAAGATAAGAAGAAAGCCAAGTATGGCAGCCTGCAGGACTTG AGAAAGAATAAGAAAGAACTGGAGTTTGAGCAAAAGCTTTACAAAGAGAAAGAGGAAATGCTGGAGAAGG AAAAGCAGCTAAAGATCAACCGGCTGGCCCAGGAGGTATGTGTCCTGCCTGCAGGCCAGGCAAGCAACCC TGGGACACAATGTGGTCGTTCTCCATGTGCTCCCAGAGGACCAGCTGGAGTTGTTCTCCTCAAATGGCAT ACAAGGGTGGAGTGAGCCCTTTCCTGCTCCCCAGCCTGGAGAGAGAGATCATGCCACCTGCCCAGGGCCA TCTGAGGTTAGCTCCTGGCTTAGGAATTGAAACTAATCTCCTTGCTTGGGGGTGTGAGTCTTGCTCCTGG CTTTGGAATTGAAACTAGCCTCCTTGGTCGGGGGGTGTGAGTCTGAGGTTAGCCTTTCTGACCAGATGGT AGGTCTCAGGTTAGCCTTTGATACACCTGGCTTAGAGATTTGAGTCTGTCCTCTTCACTCTACCCCACCA GAGTCTAAGGCTGGGCCTCTCCATCTCAGGTGTGGCTCTGAGGCTACTTAGAGTATGGTCTGCGGCTAAC CCTTCTGCCTTGCTTGTAGCTTTGAAGTTAGGCTTCCACTGACCTGTCTACGAGTCTGAATCACTCTGGC CTCCCTTCCCAGGTTATTGTAAGACCAGACCCCCCCCCACCCAACTTAGCTTGGCTCTGAGAATATGGGT CTGAGGCTAACCCCCTTATGCAGGTGGTAGGTGCGAGGTTATCTCCCAATTAATCAGGCTATCAGTCTAA GGCTGCTCCCCTCAACATAGGGTGTGTCTAAGGCTAGACCTCATCAACCTGGGAATATATCTGAGGCTGT CCCCATGAAGACATGTCCAAAGCAACCTTACACCATGAATAATTCCTATGCTAGGTGAGATGGGTAACCT TAACTCCCCAGCTGTAGGAGGTATCATTGTTTCTGCTTCTCTTTAACGCATCCATGAATCAGAATGCCAA TTTGATTAGATTATAAAACCAGAGAAGTCCTGGAAAATGTGAAATGCATTAGGTCTGACATTATGAACAA ATTAGCCACAAAATTAAAAATAAGATTGAACTTATGCTTCTGAGGGCAAGGCAGAATGGAGCAGGAAAAA AAAGAGTCAAGTTAAACTCTTGGAATGTGCTGGGGGAGGCTACAAAAACTCCATTCTTGGAAAATCATAA GAGCCTCAGGGTTCATGGGGATCTGGGATCCAGCTAATCCCTCACAATACATAAGCCCCTTTTCTGATTT TGCCTACAAGTTCTGCTTAGTGAATTTGACACCCCGCCACTCTCTTCTCCCTTGCTGCTGCCTCCTTGAG GGCCAGTTGGAACAAGCCCAGGTCTCTTTCTAGATAGCTGATGCACCTCACAGTACTCTGGAGTTTCTAA AGGAGTGCTTTCATGCTATTTCTATCCACATGTTATTCAAATGTGCCCTTTGTCCTCTCCTTTCTGCGCC GATCCTGGGTCCCAGGTGTCTGAGACAGAGCGGGAAGACCTTGAAGAATCGGAAAAGATTCAATATTGGG TGGAGAGGCTCTGTCAAACGCGCCTCGAGCAGATTTCCTCTGCTGATAATGAGATTTCAGAGGTAACAGA GCCCTTCTTTCCACATAGACCCTCCTGCTGTCTTCAGAATGACCCACTGTGGGGACAGCGGGAGGTGAGA TGACAACTAGCAAACGTCACTAGCCTCACAGTGCCCATCCACTGTCCAGGCCCACCCCTACCACCCCACT CCCCTCTTGAGGAGGAGGGATATGTCTGTATTTCTGGGTATACTCCCAGAGTGATCTCTAAGTCCCAGCT CATCTGCGATAGTCTCAGTTAGGCCTGTTGTCCTGGCATCATGACTAAGAGTCCCCCTTACACTCTCAAG GGCATTCCAGTTTAGAGAATGAACTCTGTGAACACCTTACCACCCACAGATGGCATAACTTGGGGCTCTT CTGCATTTGGGCACTCCCTAACAGCAGCCTAGTATGGCCTCAGCTGGGCATCCAGGTGGCAGAGGAATGG CGCCCCATGGTTCTGATGTAAGGGTGGTGGGTCTCCAGTAGCAAGAGAAACAGATTAGAAGAGCATAGTG CTCGCTGTATTGTGAAGTGGAGCTCTAAGCAGAGTGACAATTACAGAACTTCCTTGCAACACCCCCAGAT GACCACAGGGCCCCCGCCTCCCCCGCCTTCTGTGTCTCCCCTGGCCCCACCCTTGAGACGCTTCGCAGGC GGACTGCACCTGCACACCACTGACCTGGACGACATCCCTTTGGACATGTTCTACTATCCCCCCAAGACTC CCTCTGCCTTGCCTGTGATGCCCCACCCTCCACCCTCCAACCCACCCCACAAGGTCCCGGCGCCCCCTGT CCTTCCCTTATCTGGCCATGTGAGCGCCTCATCCTCTCCATGGGTGCAGCGCACTCCACCCCCCATTCCC ATCCCTCCCCCGCCATCCGTTCCCACCCAAGACCTCACTCCCACCCGCCCACTGCCCTCGGCGCTGGAAG AAGCACTGAGCAACCATCCCTTCCGCACTGGGGACACAGGCAATCCAGTGGAGGACTGGGAGGCAAAGAA CCACAGTGGGAAGCCCACTAACTCCCCTGTCCCTGAACAGAGCTTCCCACCCACCCCAAAGGTAATGTCC CTGTTCTGCATGCTATGTTTGGAAGTAGGAAGAGTGGGGAGAACTGCTGTTTCCCATGTCCTCCACTGCT CCTGAGAGTGGAGACAGAAAGAAACATCATCTCACCCCATTTTCCAGGAATGCCCCCTCCGTGTGCATGT GTGGACATCCTGCATGTATATGGTGGTTCTCACTGATTTTGAAGTGCTGTATTGTATGGTGAATGGCCTG GGACCTTTGGGGTAAGCAACGGTGTGTCCATTTGATATTCATTGCTCTCTCTTAGCTCTTCTTTGCTAGT GTAGGCTGGTAACTTTCAATGTAGGACTTGGAAGTCTATGTTAATGAATAGCCAGCACTCTGTCACATCC AGTCACTTCCTGATATTATCCCAGAAAGCCTTGAATATGGGAAATGGCTCCTGATTTAACGGGAAAAAAA GGGAGGGGAGGAGGAAGCAGGGGCGTATTTGGCTCTGTAAATGAAGTGATAACACTGTACCATCAAATGC AGTATTAGGACATTCCAGTGCCATTTTCTACAGTACTGGCCAACTGCACTGGCTTGAAGTGTAATACCCA GAAATTTCTGGCCAATTTCCAGCTATAGAAAAAATGAAGATGAGAGAGTTCCTAGAAATAATTTACTATT AAAAGAATAGGAATGTTTTTCTTGGATGTTAGGAAGATGAACAGTGTCTTTCTGAAAAAGACATATTTCT TATTAATTATTCGTAATCCAAAGACTATTTTGAAACATGCAATCTCTGAGGAAGACAGGGAGCTTGGATC CCATGAAGGGAAAAACAAAATATTATTCCACTCCCGTAGCCATGAGGCCAGGCTTGAGTCAGTGCAAAGG CATCTCATGTCAGCTGAGGGTAGCAGGGGTTGCTGAGGGAGGGCATAGTCAATAGCACCTGACCAGTGGT TTTTATTAACCTTCCCTGCATGGATTTGAGTTCCTGCGTGGAGAGCAGGACAAGCATCTCAGAGCACTCA GGAGAGCTTACAAGGAAGGTGGGAGTGAAGAAAGTGCCAGATGCCAGCAAGGCTGAAGCTTCCAGCGGGA GACTCTCAGAGGGACCCTTTCTGGACCTCTGGTTGGGGTCGTGAGCCCTGCAGCTTTGACAGGAAGAAAT CTGCCTGTTCTCGGGACATCTTTCCCCAGAGCCCAGCCAGGAGCTGGTTTCTAGAGCTGAGTTAGCCTTG CACAACATTTTTCTCTGTAAGTGGCCTCCATCAAGATGAGCAGTAGCTTTTCCTCAACAAATTTGATTCC ACTTTGATTGAGTACCTGCCTGGGGCCTCTCTCTGTGAAGGGGAGAGGGGAGCAGTGCTGAAGAGGATGC AGAGGAGATTGACATGCCTGTGCTTTCCAGGACTTTGCCATCTGAAGGATGAGCTGCTGCCCAGGCAGGC TTCTGCTATAAAATATGCATAAGCCATGCGCTATGGGAGGGATTCATTCTAACTGAAGATTGAAGACACC TCTGTAGAGTAGAGGGCTTACGAGCTGAGCCTTGAGGGATGGCAACACATGGAGGATGGGAGCAAGGGCA TTGCAAGTGCAGGGAACATAAAGATGGCAAGTTGGAGTAGCAGGGAGTTGGCCTGCCTGGGTTTGAATCC TGGCTGTGCCACTTACTAGCTAGGTAACTGAACACATGCTACTTCATCTATCTGAGCCTGGGCATCCCTG TCCAAAAATAGGAATGCTAATGGCAGCTACCTATTCGAATCAAATAAGTTAATACATGGACACATTCTAA GTTAAGAATGGCAAGAGTGGCAGGCACATCGTGGATGTTCAGTAGACATTAACTATGGTTATTGATAGTC CAGAGTAAAAGAAAATTTGGGTGAAGCTGCAAACCTGGGATCTTAGCAATCTCAGTGTCAGCAAAACTTT GAGTCAGGATCAAGATTCAAGACAGAGTCCAGACTTCTCAGATTCTTCAAGGCATCACCAAGTTCCCACT GTTAGTTCCTGATCAGAGCCCAGGGAAGGTTAAAAGCCCCCCAACACAAGGAGCCTCTGAAGAACTGGAC TATAAATGTCACAAGCGACATCAAAGCCAGGGTTGTCCCAGCCTCAAAAGCCAGGGGGCTGTTGCTTGGT TGGCTTCATTTGGCCCACCTCTCACCCTTGTACCACCCACCCTCCTCCTCCCTGCATGCCCCTGGCAAGC TGTCATCAGTGCTGCAGCAGGAAGTGTGAGTGACCACACGCCCACACAGTCAGCCCAGCCACCAGCAGGC CCCAAGTCATGGAAACAAACACCTGTGTTGGCTTGACACTTGTGCCTGCCACACCAGCACCGGCCATAGG GGGGTTTTCAGGGCCAGATCTATCCACAGGCACTGTCCCATGTTCTCACCATACTATTTAGTCATTCATT TATTCATTCAACACATGCTTATTGAGCACCTACTATATGCCAAGGCACTATGCAGGGCACTGGGAATCCC TGCTGGATAGACAGCTGCAGTCTCCCTTCTCAAGACAGTCTGGTGGGGAACAAAGAAAAGTAGGCACCCG CCACACCATCAGCGTGGAGACGGAGGAAGCACAGGTGCTATAATAAGGAAGAGGGCTGGAGTAGAGGAAA AGCTCAAGGGAGGCTTCCAGAAGGCAGTGACGCCCAACTTAAGACCTAGGAGGCAAAGCGGAAGAAGGAA GAGCACGTGCAAAGGCCTCAAGGCAAGAAAGCCTGGCATTTTTTGAGGCTAAAGCTAGGCAGTGTGAGGA GCGTGGCGAGGAGTGAGAGATAAGGCTGAAAAGGAAGCTAGAGAAGCTCATGAAAGGCCTTGGGAGTCAA GCCAATGAGCTCAGTAGTCAATGCGGACACTGGGGAGGGTTTGGGGGCAGGGCTGTGAACTGATTTGATA CATCTTGCCCAAAAAGATCAAGTGGGTTAGAGCCAAGCAGACAGGTTGCGTCAGCTCCCCTGGATGCCTC TCTTACTGGTCTTCACCCCATGGCCCCTAGAGACTATGTGCCTACCAACTAGGAACAGCAGATGCTTCAC ACTGTGGTCCAGGGACTGGAACTGTGGCCAAAGAGACAGCCCTTAAAGACAAGGGACACTGGATAGCACC CATGGCCACTGAGAGAAGGGTCTGAAAGTGTGTCTCCTGGGTGACACTGGCTGCTGGCACCCCCAAGCCA GGCTCTAGCTCAAGCGTCCAATTTCTTAGAGCCGCTCAGTAGTTTCTGTGATCTCAGCCCACACTGTGGC CAATGGGCTTCTCATCTCTCTGCTGAGGATCACAACCCCAGGACCTCGAGCAGTTGAATGACCAGGCTGG CTTCACATATGCATGGGTGTAGATTTGCATGTGTGTAGAAGTAGCATGGCTGGCCTTGGCCACCCCACCA TGACCTCACCTGGGTCCCTGTTAAACTAACTCCTTAGACATTTTGCCCAAGCCCACAGCCTCCACGAGGC CCTGGCGTGTCCACCATCTCCAAACCTGTCATGGTCCACCAGGAGCCCAATTTCATCTACAGGCCAGCTG TGAAATCTGAAGTTCTGGTAAGCCCCTTGGGTCCCCTCCAGGTTGTCTCTAGAGGAGCAGACCAGGGCTA CCTCCCCTGGGCTCTGCTGTCTCTGGAGGGCAAGTGAGGTGGGACAAAAATGCAGATCACAGATGCCATC TCTTAACCTTCTTATTGGCCAAGAGATGAGGCCACATGGGTGTAAGTGGATGTTGACATGACCAGTGGAA TTTCTGTTCCCCACTTGACTGAACAGCCTGGAGCTCTGTCTAAAAGTAATAATGATCGCTACGACCTGTG AAGAGCCTACTATATACCAGGCTCTGCATGGCCTCAATTAATCTTCACAGCAGGACTGTGAGATGGTTCC TGTGGTCATCCTGTTTAACACTCGAGGAAAGGGAGGTTTAGAGAGGTTACCAGAGGGGCACCAGGTTCCC CAGGCAGAGCCTGGACTTAATACTTACCCTCATGCCTTTCATACTCCAAAGCCCACGCTGTTACCCTCGT TGCCATCTTGCCAAAACCTACAGAGATTCCAGGTGCCCTGGCCCCTGCCCTAAGGCCTGTTGTGGCCTGG CATGAAACACCCTCAGATGGGAAACTGGCCAGAGCAGGTTCACTCCCTTTCTCCAACTTACTTCTCACCT CTCACTGTGACTGGAAGTCTGAGGTGTGGTCCTGGGGAAGTGAGAAATGTCCGCCAGTCTCAGTTACTGA CGGCTAAGGGAGCTGGGATTCGTGTGCACCTCCCAGAGGTGCCGACCACTGGCTGGCCTCCCATGCACAG TGAGAAGACAGTCATGTCAGAATTTTAACTTCCCTTTCAAGGAAACTCTATCCAAATGTCAGGGCAGGAC AGCTGAGATATTTATTTTGGGCCTTAACTGTCCCGTCAGCTCCCCAGAGAGCAAAGTTTTTGCTCCTGGG ACAGCCTGCGGATGCATCCATGTCATGTTCTCTGGCTAATATCAAGGGGTGGTGTCTGCTTGACAACAAC TGGGTAGCATCTTTGGGCATTGAGCAGGCCTTTAACGTAAGCCAGACTGCTCGGGGAGGGACATTGGCAC GGCAGCCCCAGACTGGCAGGCCCGAAGCCTGGCACCAGGGGGCAGCCAAGACCTATTGGTAACATCCAAT GTGGAACTTTTTTTTTTTTCCTCTGGCAGCCACAGGAGATGTTGAAGAGGATGGTGGTTTATCAGACAGC ATTCAGACAAGTAAACTGATACCCATTGTGTGTCTGGAGGTCTCCCCACCACCCCCGTCCCTCCCACTCT GTGCCACTTCTTTCTCTCTGGGAGTACCTGGTCAGGTCCATGGTGGCCCCATCTGCCACCAAGCCTCAGG CCAGAGCTGTGTCCTCCATTGCCTGCGCAGGGGTGGGGGAGGATATCATATCAGATGGGGACCCAGGGCT TATTAGACCCCATGCATGAGCTGAGAAACAGCAGTATCCCTGGGAACTCACCTCTTCTGCTGCTGTTTGT CCAGAGAGGAGCAGGGCAGAAGGAACCCTCAGAGGCCCACAGAGGCCAAGATGGGCCCTCGCTCCAGCCC TAGGAGAGAGGGAAGGGGCTGCTTAGGTGTCTCCCTGTACCTTCCCCTCTTCTTCTCCGGGCAGATCACA GCTTCACCAACCCTGCCTGACACTGAACCAGCGTCAGGGAGGAGGTGGTGGCTGAGGTCCTCCCTGTGCC TAGGGCACTCCTGTGCACAGGGACGTGGAAGTCCTTGCTGGTCCTCTGAGTGGCATCAGGCAGGCAGCCA CCTACCTCCCTGCCTCCTGGGGTACCTCCATGGAGCCAACCATTGGATTGGCTGTTTCATCACCAATGAA AGAAACCCCAGGACAGAGAGAGATCTTGCAGCCAGCCCAGGCTTCTCCAGCCTCCTCACTGATAACCCAC CAACAGACCACAAGCTGATTTGACTACAGGCAGGGAGCAGAGGGGCAGTATCAACTGTGCAGTGAGACAT AGGTGTTGGCAAAAGAGGCTGCTCCCAGCCCAAGGATTTGTCAATTTAATCTTTCCAGCAACCCTGGGTG GTAAGTGCTATTATCATACCCATTTTATCTATGAGAAACTGAGGCAGAGAGATTTGAAAATGTGCCCACG ATGGCACAGCTAATGTCAATCCCTGGATTTGAATCCAGGAGGTCGGTCTCTGCAGCCTGTGCTCTTAAAC ACTGCACCATCCTGCCTTAAAGCACTGTCGTCACACAAGAGGCCTTCCAGGACCTGGCGGTTTAGGGCAC AAACAGCCCTCACAGGGAGAGAAGCAGGGAAGTGCAGAGTCTAGGCTCCAGAGGTGGAGTCAAACCCTTG CTCCCCTGCCCACTGACTGGGTGACCTTGGGCGTGAATATCACCTCTCTGGGCCTCAGTTTCTTCCTCTG TTGAATGAGGGGTTGGGCTGCCTCTTTAAGGGCCAACCAGCTGCAGTGGCTTATGAGTCTCTGATCTAAA TTCACACAAAACACAAGTACCTGCCATCTGGCCCATCCCTGAGAGCTGGTTCTCAGGATCATGGAGCAAG GAGGCCAGAGCCAGCACTGCCCAGCCTTCCAGGAGAAACAGCCGGAGTAGGCAGGGCCCTCAAAGTCAAA GAGCATCGACTCCACATCCTGCCCAATGATCCTTCTTGCCTGTGCATTCACTGCACCCCCTCCTCTGTCT GCTGCCCACACACTGACCTGGATGTAGCTCCCAAGCTGAGCCGAGCTCATGGCCTCTTGGGGTTGAGCCT GGGTGATTGAGGCAAGTGAGGAGGGATGCCAGGCAGATGCTTGGGGATCTGTCTGCTGATATTTGGTGCT CATCTTGTGCCCGGAACCTAGTTGGTGCATTCTGAGGATAGGGGAATCTGTAGCCTCCCCACCACACAGA CCATGGGCCCCATGGGTCACTTGGTGTGGTCTAGGGACCTGCATGCTGTGGGTGGCTCCACTCAGTCTGG CGAGGCCTGCCACGGGGCTCTCCTCTGCTCCCACCTTCCATGGGGACCAGCCGTGGCTCTGCTGCCCTTG TGCTTAGCATCCTGGCCCCTCAGCCTGGGGATGCCCCTGGCTCCCACTCACTGTGTGTGACTCCCGAGGA AGGCCACATAGTTCAGGGACTACCTCACTGTGTGTTCAGGTGCCACCTCACTGTCTTGTTTCTACACCCT GGAGCCATTGTCCCCACAGCATCCCCCATCAAGCCAGGTCCCCTGAGCTGTGTGTCCTCCCTTCTCCCCT AGCTAAAGGGCCAACCTGCGCTCCGCAGAATCTGGGGAGGCCTCTTACCTTCTAGGTAAGCATTACATGA GGACACTGCCAGGCTCCAGGCCAACACTGCTTCTCAACACCACCTGCTTTCTTCTTGTTGTCCGTGGGCT CCCTCCACCATCTTGTGGCTGATTTCCAGGAACAGCCTTCTCTTGAGCTGGATGGGCCCCTCCTGTGGGG TCAGAGCACTGGGTGGAGACACCTTGGGCTTCATCCCCCAGGGCCTGGGCCTGCTCCAGTGGAGACTTGG AAGAGATGAGGTGGGGCCTAAAGGACTTGAGGCTGGGGCTGAGACTTTCAGCAAGGCAGATGCCGCCTCT CCAGACCATCTAGACGTCACTGGTGCCCCTGCAGCCCCTGACGCTTGTGCCGCTGAAGCAGGGCAGGGTC AAGATCCTCTAAAGTCTTCCTCAGCCTCCTGCTTGTCCCTGAACAGGGGTGCCCTGGCTGCTAGGGCTGC CGGCCTCCTGTCTGCATCCCGTACCCTGGCCGTGCCTTCTCCCGCCCTACCCCTCACTTCTGACCCTTGG ATTCCGACCATTCATCCCCCTACTCCTCGGCTCTGACCCTCAAGACCCTCTGCTGTGTTGCCCTAAAGCC CTCCCTTTGCTTCCAGGATTTCCGGAAATATGAGGAAGGCTTTGACCCCTACTCTATGGTAAGAGATGAC GCTTCTCTCCTGGACAAGTAACCCCAGGAACAGGGCAGTGTGGGGGTTAGAGGGTTTGATAGTGGTGCAT TCTGGGCCTTGGGGTCCTGGGATGAGGTGGGGCACAGAGGAGCCCCAGTGATGCCCCAGCTGCTCTTCCC ACGAAGATTCCTTCCAAAGGGCACTCCAGTGTGAACTGTATGGTGCACATGCACGTGTGTGTGTCCACTG TCCCCATGGGGCCTGGGACCCCCAGTTGAAGACCAGTAGGGGTGGGGCTGGGCACGGTCCCCTTGCCCAT GTGCTCTGTGGGGCCCAGTGTCCCATAGGTGCCTGGATTCCCCTTCCAGCCCTACCCCAAGCGCCATCCT TCAGGCCAGCTCAAAGCTTCCCACTGTCTTTTTCTCTCTAGTTCACCCCAGAGCAGATCATGGGGAAGGA TGTCCGGCTCCTACGCATCAAGAAGGTACCTGGGCATGTGGAGGCCGGTGGGCCGCCATCCCTCTCTGTG CCTGCCCCTCCTCCCTTGGTCTCCTGCCTCTACTCTCAAGGTCACTCCTGGGTGGTCTCTCAGGTCCCCA CTGTCCTCCCCTCTCCCACGGAGACGCCCCTCTGTTGTAGGGCCGCATACCCAGGCCCCACTTGGCACCA AGGCTGCGTTTTCTCCAGATGGCACTGCCGGTGACCCCATGGCTTCTTCCACTCTTACTGTGGCTCTGTC AAGAGACTCCTTGGTGCCCAGGTGTCCACAGGCTGCTGTCTGCTTGGCTCCCTAAGGCCTGTTTTCCTCT AACCAGGAGGGATCCTTAGACCTGGCCCTGGAAGGCGGTGTGGACTCCCCCATTGGGAAGGTGGTCGTTT CTGCTGTGTATGAGCGGGGAGCTGCTGAGCGGCATGGTGAGTGGAGACTAGCCACACCCAGGTTTGGGGA TGATACAGTGGTTAGACGGGGCCCTCCCGGAAAGCAAACAGGTGACCACTTGGAGTGGGCTGACGGTTGC TGGAGAATGCCCTCCCACTCGGGTCCATCCATCCGACTGCCTGTCCAATCCCTGGGGGCATGGGATGGCG CCGGGACCTGTGAGTACACAGCCAAGCCAGATGCCACCGTGCCCTCAGGGGGTCCCCAGCCAGGGTGGGA GACGGACTCAGAATTGCCAGATACTGAAAGTCACAGCATGGTCTGCTAAGGGCTGACGGGGAACTCAGAG TGGAGGGAAGCCATGGGAACCCTGAGGGGCCTCTAACCCACCAAGAGGAGATGGGAGGCCAGGAGTGCTC CTCAGAGGGGCGAACCCTGAGCTGAGCATAGTCAATGTCAGCCTCGCGAAGGGGAGAAAGGGCTTTCGAG GAAGAGGAGCAGCACGTGGAAACCCCCGAAACCTTGCCTGTCCTTTCAGTGATGGTAGGAGCCGAACGTT TGGCCAGAACTAGCCATGTGCCAGAAGCTATTCATCTGGTTTGCAGCCCTGTGTCTGAGCGTTTCATGGA TATTAACTCACTTAATCCTCACAACAACCCTGAAAGCAGGTTCTGTTATTATTCTTATTTTACAGCTGAG GAAACTGAGGCTCAGAGAGGTTAAAGTATTTGTTCAAGGACCCACAGCCAGGAGAAGGTGGAGGCAGGAC TTGAATCCAGGCAGTTTGGTCATTTTGCTTTACTGTCCGGCACAAGTGCCACCTCTGTCTGAGGTCTTCT GCAGCCTTGTCCCTTCCCAGAGGGCCAGAGGCCCCCATACCCTGTGTCTCTCTTCTCATTTTGCCTTGTT CTTTATCCCCTTATCTACAAAAACACCCTCTGCTGATGAGTGAAACCTTTGCAGACCCCAGGCACAGTCT CTTGCTTCAAACCATCACCCCGTTCACCTGTCGGACAGTGTCTGAAACCCCACCATTGGTGATTTCTTCT TCCATGTCAAGGAAGCTCCTGAGTCCTTTGTGGCCCTTTGTGGAGATGTAGGTGCCCTTGGAGGAGGAGC CCCAGGCCTCTTACCTTCCCAGGCCAGAGTGGGGGACCCTATGAGCAGATCCCTTCCAGGCAGTCCTAGG CTGGAGCCAGGCTGTACCATAAGCTGGAGGTGGTAGAATGGAGGTGGTAAGAGGTAAGGGGCAGGAAACA GGGATGGGAAAGGCCCTTGGGGGCTGGCAACCAGACCTCTGTGGGTTACTAAGGTGAGGTATGGGCATTG GGAGCCCTGGATACAAGTCCAGCTCTGCACCCATGACCTTGGTGACTTCACACTTTAAGCTTTCATTTCA GCCATAGAAGGGGGACCTGCCCAGCTGGGCAGCTGCCCCAGCCCATCAGTGCCCACCCAGGCCCCACCTT CTTCTTCTGTCTTCATTTCTCTGTCACCTGGTGACACTTCTGTGATACCTGCCTGCTGTGTCTAGCAGAG AGAGGGGACCAGGATGGATGGGTGACTCTCCTGGGTCCTTCCCACTTACAAAGCCCCAACCCAACCACTG CCTTATTGCCCCTGAGACTCTGTCATGGATTTGTACAAAATGAAAAGGTGAAAGTCACCCATCCCCAGTT GCACTGCACAGAGGCAACTGCTTTCTGTGGTTTGGTCCTGCACTGCTTTGAACATAACTAGTCACTGATG AAGCTTCCCTAGGAGCACGTGTGTTTTAAGCCACCATGGCCACCATTGTCAGTATCATACACCACATTCC TATGGGCCTTCATGCCACAAGGCTCCTGGGTGATCTATTTCAATGTAACCTGGAGAGTGTTCTGTGGACA TCAGGACTGGGAGAAATTCCTCCAAAAAGGGCTCTGATGTCAAAGAGGTGTGGAAAACCACGCACAATCT GTCTACCTCTTGGAAAGCTGCAGTGCATGTTAGCACATTCAAGACTGACAAATCCTGCAGTGAGTAGCTC TGTTCAGCTTATAACTCAGCTTTCCCCAAAATTATTAGATCCCAGGCAACTCTTTCAGGAGCACCTTATT ACAGCTTCATTTATTCAACAAATATCTACTGAGGTCCTATTTTGTGTCAGGCATTATGTTAAGTGCTGGG GATATTATGGTGAACCAAAAAGACAATCCCTGCCCACGTGGAGCTGACAGTGTGGTGGGAGAGACCATCA GTAAACAAACAGATTAATGATTACGAATTGTGGAAAATGCCAAATAAGAAAAGATTGGGATGCTGTGAGA GAATAGGCAAGATCTACATTCGACTGAGCGGGGGTCAGAGAAGCCCCTTCTGACATTTCCTCTCAGACCT AGAAGAAGAGAAAGCAAGGTAGGGAACAGCGACATGAAGCCTCTGAGGCAGGAGAGAGCATGGCAGCTCA GGGACCTGAACAGACCAGCATGACTGGCAACAGGGAGGGCCGGCTGGCAGAATTGACTCAGGCCTCATAC TGTGCTGGAAATGCAGGTCTGTGTCCCTCTGTAATAACAGAGGCTCATCATCAATGATATCCAGGTTCTC CTGAGCTGGGGTGAGGGGGTGTGGAAGGGACAGGGACTAAATGCCCTTTGACTAGCCACTAACCAGGTGG CTAGTTTCCCCTCATGCTTTCTGAGTCCACATGAGCTTTCAGAACCCAGGCTCAGGTCTCTTCTGCTGTC TGGCAATGACCCCCCTTTGCCAAGCCCTGGGCCAGGCACGTGTCACATACAGCCCAGTTGGCCAATCAGC CTCATCTGCCTGCAGGTGGCATTGTGAAAGGGGACGAGATCATGGCAATCAACGGCAAGATTGTGACAGA CTACACCCTGGCTGAGGCTGAGGCTGCCCTGCAGAAGGCCTGGAATCAGGGCGGGGTAAGAATAAGGCCC CTCCCTCCTTTCCTCCCTCACCTGCCTGCCTCAAACCCTGGCCTCTGCAGCCAGGTCTCACAATAGGATG CCTCATTCCAGGGTGGGCATCTGGAGTCCAGGCAACACTTTGGTGACACCATACCCCATCCAGCCTGTGG TTTAAATCTGACAAGATGGGATTCAGAAAAATAGATGTCAATTCCTGACCTTGGATCCAAAAAGCCAGTG GCTTAAACAGACTCTTGAAGCCAGGGCATGGCAGGTCACCCAAGAAAAAGACTTAAGGTCTTTTCTAAGT GCACACTGAACAAGAATCAAGAGAATTCTGGGGGCTACCAGAAAGCATTAACAAAAGCAGAGAACCCAGG ATGAAGGAGGGGCTGGTGGGAATCTGCTCTGCACTCATTAGACACCCACCTGGATCACGGCCACTGCATA AGATTGCCCAGGCTGTGCACTACATAATCTGAGGGGGTGCCCTTTTACAGACTGTAGTGTGAATGGTGCC TGCTCATGGTGTGCAATGCACAACCTGTGCAACTGTATGCAGGCAGCCGAGCCTGAGGTATTAAGTTCAG TGCCGAGGAAGCTGACCAGATGGGCCTGGGACCCACATGAAGGGATGTGGAGAAGAGAAGACTCACGGGT AACATGATGACTATCTTTGATTATCTGAAGGTCTGCATTAGGGCAGAGGGAGCAGAAGTGTTCTCTCTGA TTCTTGAGGGAAGACCTGGATTGGATGGAGGGAAGTCCTGGGGAAAGAGAGAGAGATTTCAGCTCAATAT TAGGAACCAGCTCATGGTAGAGGGGCCCAGTGATATTTCCAATACTTTTCAGGGGATACACCTAAGCCAA GGAGGGAGAATGAGGGGCAAGTCAAGGATGGCAGTAAAAGGGATTCAGGTGTTAGGATCAAAAAGCTGGG CCAGAAGTCCCCCACTTGATTGTGCATCAGAAAGTGCGTCGGAATTACCCAGAGAGGTTGTTAAAAGTAC TATTTCCCAGGACTCACCCTTGACTTCTGGGGGCCAAGTCTACGAGCCTACACTTTTAAGAAGTTCCCCC AAGTGATTCTGAGGTTGCTGCCTGTCCCCGGTCCATAGATTGACATTTGGGAGCTGAGTGTCATTCAAGG GCCTTGCAGCCCTGTCCTCTATGGTCCCGAAGCCTCAGAGACTAGAAACGTCCTCAGACCATGGAAGTCA CAGTGGGCCCCAGGTGGGCCCGTGGGAAGAAGGTGCAGCCTGGCTGATCCTAGGCCATGGGGCCCAGAAA TGGGGATGGAGTGCCGGGGCAGATGCACCATCCAACTGAGTGTGCCCCAGAGTCACACGGCTTCTCCCCA CAGGACTGGATCGACCTTGTGGTTGCCGTCTGCCCCCCAAAGGAGTATGACGATGAGCTGTAAGTGTGTG CAAGCACCTAGCCTGAGACCTCTTCTTCCTTCTCCAGAATCTCAGCCACCTTTCTCCAGCCCATCCCCAG CCTTCTCCCAGCCTGAAGGAATGGCCCAAGCACGCAGCTTCTCATAGCCAGAGCTCCTAGAAAACTCCTG GACTAGAGCCAAGTCATTGTCCTTAAGCAGTGTCTGAGCTGCCTCCCGGGCAGTCTTGTCCAAATTCTTC TCTACTATGGGGAATTGAGGCATGAGGTCTTAGACCGGGTAAGCAGAGACGTTGGGAAAAAGACTCAGGA TTGTTAATTCCCCACTCAGAACTTTATCCCCTGCCCCATTATTAGATGGTTAGAAGGTGTCTGTGTCCAT CCTTCACTCTCTGGAAGGTCTTCCTGATGTCTAACTGCATTCACTCATACTGTGCCTCTAGGCAGCCGGG ACCACAGGCTTTTGTCCCCACGCTGTGGGATCTCCAGGGAGCTTTGGCCTAGACTGTCTCTCTCTGTGAT TCCCTGTGTGTCTGTCTCTTGTGTCCTGTGGGTCTCTCTGTCTTCTCTCCTCCTCCCTCTCTGTCTTTCT TTCACCCTTTCCTTCCTTCCTGTCAACATCTTATCTGCCCCCCTCCTTCCCCTTCATCCCGGTCCCCTTT CTCTCTCACTGTCTCCTATTCTTTCTTCCTGTTTCTCTTCATCCCTGTCTCTGAGTCCCTGTTCCTCTGT CCTTGTCATTCTGCATCCATTCTTACCTCTTTGTCTGCCTTTCTCTGTTTCTCTGCCTCTGTGTGGTGTC TCACCTCCATCCTCACCTCATCCCATCACCTCCCCAGCCCTCACCCACCCACCACTCACCCACTCACTGA CCATGCCCTGCCTCCCTGTCGTGGCTGGGCCTGCTTGCTCCCCGTGCCCAGCAGAATCTGAGCTCTACAC ATGTCTTGGAGAAACCAGGGTCTCGCAGCTCCTAATTCTGGAACCCAGGGGCTAGGCAGAACCCGAGGCA GGAGCCCAGTGAAAGGAGAAGCCCCATGGAGCTCTGCCTGGGAGTAACCAAGCCTGTTTTGTGTTTCTTG CTCTGCTCTGTATATATAGAGCTTCTCTTCCCTCCTCCGTAGCTGAAAGCCCCCAACCGGTCCGAAAGCT CCTTGAAGACCGTGCTGCCGTGCACAGACACGGGTTCCTCCTGCAGCTGGAGCCCACGGTGAATAGGCAG GCGGGCCACAGGGCCCTGTGTGTCCCTGCTGCTTGCAGTGGCCATCTGCTGCCCACGCTGTCAGCAGGTT CTTTGGACTGGCGTCTGGAGGGTACACAAGGCGCCATCCCTGAAGTGCTGCCTGGGGCCTGCTGTTGGCC ACAGTGGAATTCCTCAGACTCAAAGCCCTCCCCTCAGGGAAGTGGTGCAAAGCCCAGTCTGTAGTACTTG CTTGGGACCCAGGTGTCCTGACTCATCACGGCCCTGGGACCTGCTTTGGGTCCCAAGCAGCACCCAAATG AGCAGGATGAAGCCCTGGGCAACATTCTCTGAGGGACACAGACAATGCCTCGAACCAGGCATGTGGGGCT GAAGGAGCCCACAGGAAGCCTGGCTGGAATTGCCCCCAAGAGATGTCCTCAACAGAATGTGAAAATTCCC CTTCCTGTGAATGCCAACCTCCTGGGAGCTCTTGCTCCACCATGGCCCCCACACTTGGCCAGAACCAGGG CTATTAAGAGGTTTTGAAGGCTGGTCCAAAGAACCAGGGTTGGTGGATTAGAGTTGCTCATGTCCTGTTG TGCCCTGTCATGGCCTGAGCCGTGCTTAGACCAAACGGTCTTCTCTGCCTTCTCCCTTCCTTGGCTCTGG GCTCTATCTGTGGGATATACCGTGGAACCCAGCTGTAGGATGTGTTTCTCACCCTGTGATAGGGATGTGC CCGTGGACAGAGCTGGCAGGTGGCTGTGAAACTGGTGTTTGGTGTGGCCTGAAGCCACAGATGGCAGCAT CTGGGGCAGACCCAAGCCTGGACTTGACTTTTCTGTTACAACTTTCCCAAAACATTAGGGCCTCATGCTC CCAAGACACTTGGCCGGGTAGACCATGGCTTCTGGGGTGGCCTGCATGGCCCTATGTTTTCTGTTACTTG CCTTTTGCAAAGGACTCTTGCCCCTGTTCCTCCCAGTCTCCTCCTTCCCCCATCCCAGGTGTCCCTCCCG CTTTCTCCCTGGCCTCCTGTGTGCTGTGGCTGTGGCTGGTGTGTAGCCACTTGGGGCCTGCACCCAGAGG GGTCTCCAAAGGGTGGCAGGGCCTTGTGCTGCCAGAGTGGGTACTCCCCCTTGTGGGGCCTTGCTCTGGC TGGGCTGAGTGTGCACCCACAAAGCCTGTATCCACCTGGGCTGTTTCCACTTCCCTGCAGGACCTTCTTC TGAAGTCCAAAAGGGGAAACCAAATTCACCGTTAGGAAACAGTGAGCTCCGGCCCCACCTCGTGAACACA AAGCCTCGGATCAGCCTTGAGAGAGGCCACACTACACACACCAGATGGCATCCTTGGGACCTGAATCTAT CACCCAGGAATCTCAAACTCCCTTTGGCCCTGAACCAGGGCCAGATAAGGAACAGCTCGGGCCACTCTTC TGAAGGCCAACGTGGAGGAAAGGGAGCAGCCAGCCATTTGGGAGAAGATCTCAAGGATCCAGACTCTCAT TCCTTTCCTCTGGCCCAGTGAATTTGGTCTCTCCCAGCTCTGGGGGACTCCTTCCTTGAACCCTAATAAG ACCCCACTGGAGTCTCTCTCTCTCCATCCCTCTCCTCTGCCCTCTGCTCTAATTGCTGCCAGGATTGTCA CTCCAAACCTTACTCTGAGCTCATTAATAAAATAGATTTATTTTCCAGCTTA Download Select all
Length	50522
OMIM ID	605242
HGNC ID	HGNC:12597
Unigene ID	Hs.502072
Ensembl ID	ENSG00000006611
PharmGKB ID	-

mRNA Information

mRNA ID	NM_001297764.1
Exon	join(1..145,11095..11162,12875..13018,13125..13263, 17086..17194,17377..17401,17607..17664,17976..18070, 19882..19966,20939..20998,21491..21633,23006..23071, 23423..23547,26943..27016,42437..42478,42882..42935, 43267..43366,46146..46255,47604..47659,50041..50522)
mRNA Sequence	>10083 AGCTCCGAGGGCGGCTGGCCCGGTCGCGGTCGCGGCTCTTTCCAGCTCCTGGCAGCCGGGCACC CGAAGGAACGGGTCGTGCAACGACGCAGCTGGACCTGGCCCAGCCATGGACCGAAAAGTGGCCC GAGAATTCCGGCATAAGGTGGATTTTCTGATTGAAAATGATGCAGAGAAGGACTATCTCTATGA TGTGCTGCGAATGTACCACCAGACCATGGACGTGGCCGTGCTCGTGGGAGACCTGAAGCTGGTC ATCAATGAACCCAGCCGTCTGCCTCTGTTTGATGCCATTCGGCCGCTGATCCCACTGAAGCACC AGGTGGAATATGATCAGCTGACCCCCCGGCGCTCCAGGAAGCTGAAGGAGGTGCGTCTGGACCG TCTGCACCCCGAAGGCCTCGGCCTGAGTGTGCGTGGTGGCCTGGAGTTTGGCTGTGGGCTCTTC ATCTCCCACCTCATCAAAGGCGGTCAGGCAGACAGCGTCGGGCTCCAGGTAGGGGACGAGATCG TCCGGATCAATGGATATTCCATCTCCTCCTGTACCCATGAGGAGGTCATCAACCTCATTCGAAC CAAGAAAACTGTGTCCATCAAAGTGAGACACATCGGCCTGATCCCCGTGAAAAGCTCTCCTGAT GAGCCCCTCACTTGGCAGTATGTGGATCAGTTTGTGTCGGAATCTGGGGGCGTGCGAGGCAGCC TGGGCTCCCCTGGAAATCGGGAAAACAAGGAGAAGAAGGTCTTCATCAGCCTGGTAGGCTCCCG AGGCCTTGGCTGCAGCATTTCCAGCGGCCCCATCCAGAAGCCTGGCATCTTTATCAGCCATGTG AAACCTGGCTCCCTGTCTGCTGAGGTGGGATTGGAGATAGGGGACCAGATTGTCGAAGTCAATG GCGTCGACTTCTCTAACCTGGATCACAAGGAGGGCCGGGAGCTGTTCATGACAGACCGGGAGCG GCTGGCAGAGGCGCGGCAGCGTGAGCTGCAGCGGCAGGAGCTTCTCATGCAGAAGCGGCTGGCG ATGGAGTCCAACAAGATCCTCCAGGAGCAGCAGGAGATGGAGCGGCAAAGGAGAAAAGAAATTG CCCAGAAGGCAGCAGAGGAAAATGAGAGATACCGGAAGGAGATGGAACAGATTGTAGAGGAGGA AGAGAAGTTTAAGAAGCAATGGGAAGAAGACTGGGGCTCAAAGGAACAGCTACTCTTGCCTAAA ACCATCACTGCTGAGGTACACCCAGTACCCCTTCGCAAGCCAAAGTATGATCAGGGAGTGGAAC CTGAGCTCGAGCCCGCAGATGACCTGGATGGAGGCACGGAGGAGCAGGGAGAGCAGGATTTCCG GAAATATGAGGAAGGCTTTGACCCCTACTCTATGTTCACCCCAGAGCAGATCATGGGGAAGGAT GTCCGGCTCCTACGCATCAAGAAGGAGGGATCCTTAGACCTGGCCCTGGAAGGCGGTGTGGACT CCCCCATTGGGAAGGTGGTCGTTTCTGCTGTGTATGAGCGGGGAGCTGCTGAGCGGCATGGTGG CATTGTGAAAGGGGACGAGATCATGGCAATCAACGGCAAGATTGTGACAGACTACACCCTGGCT GAGGCTGAGGCTGCCCTGCAGAAGGCCTGGAATCAGGGCGGGGACTGGATCGACCTTGTGGTTG CCGTCTGCCCCCCAAAGGAGTATGACGATGAGCTGACCTTCTTCTGAAGTCCAAAAGGGGAAAC CAAATTCACCGTTAGGAAACAGTGAGCTCCGGCCCCACCTCGTGAACACAAAGCCTCGGATCAG CCTTGAGAGAGGCCACACTACACACACCAGATGGCATCCTTGGGACCTGAATCTATCACCCAGG AATCTCAAACTCCCTTTGGCCCTGAACCAGGGCCAGATAAGGAACAGCTCGGGCCACTCTTCTG AAGGCCAACGTGGAGGAAAGGGAGCAGCCAGCCATTTGGGAGAAGATCTCAAGGATCCAGACTC TCATTCCTTTCCTCTGGCCCAGTGAATTTGGTCTCTCCCAGCTCTGGGGGACTCCTTCCTTGAA CCCTAATAAGACCCCACTGGAGTCTCTCTCTCTCCATCCCTCTCCTCTGCCCTCTGCTCTAATT GCTGCCAGGATTGTCACTCCAAACCTTACTCTGAGCTCATTAATAAAATAGATTTATTTTCCAG CTTA Download Select all
Length	2180

CDS Information

Location	join(110..145,11095..11162,12875..13018,13125..13263, 17086..17194,17377..17401,17607..17664,17976..18070, 19882..19966,20939..20998,21150..21206,21491..21633, 23006..23071,23423..23547,28127..28176,32363..32515, 33896..34012,34579..35061,38468..38587,39720..39770, 42437..42478,42882..42935,43267..43366,46146..46255, 47604..47659,48740..48848,50041..50085)
CDS Sequence	>lcl\|NM_001297764.1_cds_NP_001284693.1_1 [gene=USH1C] [protein=harmonin isoform c] [protein_id=NP_001284693.1] [location=110..1711] ATGGACCGAAAAGTGGCCCGAGAATTCCGGCATAAGGTGGATTTTCTGATTGAAAATGATGCAGAGAAGG ACTATCTCTATGATGTGCTGCGAATGTACCACCAGACCATGGACGTGGCCGTGCTCGTGGGAGACCTGAA GCTGGTCATCAATGAACCCAGCCGTCTGCCTCTGTTTGATGCCATTCGGCCGCTGATCCCACTGAAGCAC CAGGTGGAATATGATCAGCTGACCCCCCGGCGCTCCAGGAAGCTGAAGGAGGTGCGTCTGGACCGTCTGC ACCCCGAAGGCCTCGGCCTGAGTGTGCGTGGTGGCCTGGAGTTTGGCTGTGGGCTCTTCATCTCCCACCT CATCAAAGGCGGTCAGGCAGACAGCGTCGGGCTCCAGGTAGGGGACGAGATCGTCCGGATCAATGGATAT TCCATCTCCTCCTGTACCCATGAGGAGGTCATCAACCTCATTCGAACCAAGAAAACTGTGTCCATCAAAG TGAGACACATCGGCCTGATCCCCGTGAAAAGCTCTCCTGATGAGCCCCTCACTTGGCAGTATGTGGATCA GTTTGTGTCGGAATCTGGGGGCGTGCGAGGCAGCCTGGGCTCCCCTGGAAATCGGGAAAACAAGGAGAAG AAGGTCTTCATCAGCCTGGTAGGCTCCCGAGGCCTTGGCTGCAGCATTTCCAGCGGCCCCATCCAGAAGC CTGGCATCTTTATCAGCCATGTGAAACCTGGCTCCCTGTCTGCTGAGGTGGGATTGGAGATAGGGGACCA GATTGTCGAAGTCAATGGCGTCGACTTCTCTAACCTGGATCACAAGGAGGGCCGGGAGCTGTTCATGACA GACCGGGAGCGGCTGGCAGAGGCGCGGCAGCGTGAGCTGCAGCGGCAGGAGCTTCTCATGCAGAAGCGGC TGGCGATGGAGTCCAACAAGATCCTCCAGGAGCAGCAGGAGATGGAGCGGCAAAGGAGAAAAGAAATTGC CCAGAAGGCAGCAGAGGAAAATGAGAGATACCGGAAGGAGATGGAACAGATTGTAGAGGAGGAAGAGAAG TTTAAGAAGCAATGGGAAGAAGACTGGGGCTCAAAGGAACAGCTACTCTTGCCTAAAACCATCACTGCTG AGGTACACCCAGTACCCCTTCGCAAGCCAAAGTATGATCAGGGAGTGGAACCTGAGCTCGAGCCCGCAGA TGACCTGGATGGAGGCACGGAGGAGCAGGGAGAGCAGGATTTCCGGAAATATGAGGAAGGCTTTGACCCC TACTCTATGTTCACCCCAGAGCAGATCATGGGGAAGGATGTCCGGCTCCTACGCATCAAGAAGGAGGGAT CCTTAGACCTGGCCCTGGAAGGCGGTGTGGACTCCCCCATTGGGAAGGTGGTCGTTTCTGCTGTGTATGA GCGGGGAGCTGCTGAGCGGCATGGTGGCATTGTGAAAGGGGACGAGATCATGGCAATCAACGGCAAGATT GTGACAGACTACACCCTGGCTGAGGCTGAGGCTGCCCTGCAGAAGGCCTGGAATCAGGGCGGGGACTGGA TCGACCTTGTGGTTGCCGTCTGCCCCCCAAAGGAGTATGACGATGAGCTGACCTTCTTCTGA Download Select all
CCDS ID	CCDS7825.1

Protein Information

Protein ID	NP_001284693.1
Protein Name	Usher syndrome 1C (autosomal recessive, severe)
Molecular Wt. (Da)	60198
Protein Sequence	>10083 MDRKVAREFRHKVDFLIENDAEKDYLYDVLRMYHQTMDVAVLVGDLKLVINEPSRLPLFDAIRP LIPLKHQVEYDQLTPRRSRKLKEVRLDRLHPEGLGLSVRGGLEFGCGLFISHLIKGGQADSVGL QVGDEIVRINGYSISSCTHEEVINLIRTKKTVSIKVRHIGLIPVKSSPDEPLTWQYVDQFVSES GGVRGSLGSPGNRENKEKKVFISLVGSRGLGCSISSGPIQKPGIFISHVKPGSLSAEVGLEIGD QIVEVNGVDFSNLDHKEGRELFMTDRERLAEARQRELQRQELLMQKRLAMESNKILQEQQEMER QRRKEIAQKAAEENERYRKEMEQIVEEEEKFKKQWEEDWGSKEQLLLPKTITAEVHPVPLRKPK YDQGVEPELEPADDLDGGTEEQGEQDFRKYEEGFDPYSMFTPEQIMGKDVRLLRIKKEGSLDLA LEGGVDSPIGKVVVSAVYERGAAERHGGIVKGDEIMAINGKIVTDYTLAEAEAALQKAWNQGGD WIDLVVAVCPPKEYDDELTFF Download Select all
Length	533
Uniprot ID	P54760
Ensembl Protein ID	ENSP00000350896

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
S	Phosphorylation	283
S	Phosphorylation	283
T	Phosphorylation	285
T	Phosphorylation	285
S	Phosphorylation	287
S	Phosphorylation	287
S	Phosphorylation	327
S	Phosphorylation	327
S	Phosphorylation	432

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING) View

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
4647	MYO7A	2043	NP_000251.3	in vitro;in vivo	1 248 599 012 588 790
64072	CDH23	5699	NP_071407.4	in vitro;in vivo;yeast 2-hybrid	124 071 801 258 879 000 000 000

Pathway Information

No matching records could be found.

Structure Information

PDB ID	1X5N
Resolution	-
Method	solution NMR
Chains	A
Molecule	Harmonin
Model	View

Domain Information

ID	Location	Description
cd07353	Feb-80	harmonin_N
cl11968	Feb-80	harmonin_N_like superfamily
cd00992	85-165	PDZ_signaling
cl00117	85-165	PDZ superfamily
cd00992	209-289	PDZ_signaling
cl00117	209-289	PDZ superfamily
cd00992	451-538	PDZ_signaling
cl00117	451-538	PDZ superfamily
cd07347	Feb-80	harmonin_N_like
smart00228	84-166	PDZ
smart00228	218-289	PDZ
pfam00595	87-165	PDZ
pfam00595	211-283	PDZ
cd00136	97-165	PDZ
cd00136	220-289	PDZ
smart00228	451-537	PDZ
cd00136	472-528	PDZ
cd00988	105-166	PDZ_CTP_protease
cd13933	16-79	harmonin_N_like_u1
cd00988	221-303	PDZ_CTP_protease
cd07356	Jul-78	HN_L-whirlin_R1_like
cd00987	463-537	PDZ_serine_protease
cd00989	114-164	PDZ_metalloprotease
cd00987	235-299	PDZ_serine_protease
pfam13180	97-166	PDZ_2
pfam00595	460-525	PDZ
cd07354	Mar-77	HN_L-delphilin-R1_like
cd00991	111-166	PDZ_archaeal_metalloprotease
cd00988	477-550	PDZ_CTP_protease
cd00989	228-289	PDZ_metalloprotease
cd13932	29-77	HN_RTEL1
cd00987	98-165	PDZ_serine_protease
cd00989	475-514	PDZ_metalloprotease
pfam13180	221-271	PDZ_2
cd00991	234-288	PDZ_archaeal_metalloprotease
cd00990	472-507	PDZ_glycyl_aminopeptidase
pfam13180	479-512	PDZ_2
TIGR02037	96-289	degP_htrA_DO
TIGR00225	96-164	prc
PRK10942	111-282	PRK10942
COG0793	96-165	CtpA
COG0793	221-299	CtpA
TIGR03279	238-294	cyano_FeS_chp
TIGR02794	302-383	tolA_full
pfam00769	294-435	ERM
COG0793	437-522	CtpA
PLN00049	464-523	PLN00049
PRK09510	301-353	tolA
PRK14474	306-377	PRK14474
COG0265	226-299	DegQ
pfam13868	298-358	Trichoplein
pfam05672	302-357	MAP7
COG3975	235-277	COG3975
COG3064	300-358	TolA

Ontology Information

HPRD ID	587
Molecular Class	Unclassified
Molecular Function	Receptor activity (GO:0004872)
Biological Process	Cell communication (GO:0007154); Signal transduction (GO:0007165)

SNP Information

View SNP Geneview Report

Drug Information

No matching records could be found.

External Links

ArrayExpress GO
ICGC GO
Cancer3D GO
COSMIC GO
NCG GO
TSGene GO
Tumor Gene Family of Databases GO
CCDB GO
G2SBC GO
Osteosarcoma Database GO
RCDB GO

ArrayExpress	GO
ICGC	GO
Cancer3D	GO
COSMIC	GO
NCG	GO
TSGene	GO
Tumor Gene Family of Databases	GO
CCDB	GO
G2SBC	GO
Osteosarcoma Database	GO
RCDB	GO