Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| USP22 | 23326 | ubiquitin specific peptidase 22 | 17 | KIAA1063 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 21337558 | 2011 | Cell line : - Source : - Sample Type : CRC tumor and normal tissues No. of Sample : 43 CRCs and normal tissues and 192 CRC tumors Stage : - | real time RT-PCR, Western blotting, and immunohistochemistry | Up-regulation | - | USP22 might be an independent predictive factor for CRC prognosis and aberrant expression of USP22 may play an essential role in colorectal carcinogenesis and liver metastasis. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Ubiquitin-specific peptidases |
| Description | - | Chromosome | 17 |
| Location | 17p11.2 |
| Start | 20902906 |
| End | 20946722 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 43817 |
| OMIM ID | 612116 |
| HGNC ID | HGNC:12621 |
| Unigene ID | Hs.462492 |
| Ensembl ID | ENSG00000124422 |
| PharmGKB ID | PA37247 |
Protein Information
| Protein ID | NP_056091.1 |
|---|---|
| Protein Name | ubiquitin specific peptidase 22 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 525 |
| Uniprot ID | Q9UBE8 |
| Ensembl Protein ID | ENSP00000384625 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| K | Acetylation | 129 |
| S | Phosphorylation | 237 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd02660 | 176-518 | Peptidase_C19D |
| cl02553 | 176-518 | Peptidase_C19 superfamily |
| cd02661 | 176-517 | Peptidase_C19E |
| cd02257 | 177-517 | Peptidase_C19 |
| cd02674 | 177-517 | Peptidase_C19R |
| cd02667 | 177-517 | Peptidase_C19K |
| cd02659 | 174-510 | peptidase_C19C |
| cd02663 | 177-517 | Peptidase_C19G |
| cd02668 | 177-505 | Peptidase_C19L |
| cd02671 | 177-517 | Peptidase_C19O |
| cd02669 | 65-517 | Peptidase_C19M |
| cd02658 | 177-517 | Peptidase_C19B |
| cd02664 | 177-517 | Peptidase_C19H |
| cd02662 | 177-517 | Peptidase_C19F |
| cd02657 | 177-517 | Peptidase_C19A |
| pfam02148 | 63-123 | zf-UBP |
| cl09957 | 63-123 | zf-UBP superfamily |
| cd02666 | 177-517 | Peptidase_C19J |
| cd02673 | 460-517 | Peptidase_C19Q |
| cd02670 | 399-517 | Peptidase_C19N |
| cd02665 | 356-517 | Peptidase_C19I |
| pfam00443 | 175-517 | UCH |
| COG5560 | 163-517 | UBP12 |
| COG5533 | 177-521 | COG5533 |
| COG5077 | 174-509 | COG5077 |
| pfam13423 | 177-496 | UCH_1 |
| COG5207 | 63-433 | UBP14 |
Ontology Information
| HPRD ID | 12095 |
|---|---|
| Molecular Class | Unclassified |
| Molecular Function | Molecular function unknown (GO:0005554) |
| Biological Process | Biological_process unknown (GO:0000004) |
Drug Information
No matching records could be found.