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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
ZC3H13 23091 zinc finger CCCH-type containing 13  13DKFZp434D1812 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
21388066   2010Cell line : -

Source : -

Sample Type : CRC tumor and normal tissue

No. of Sample : 30 GC samples with high MSI (MSI-H), 15 GC samples with low MSI (MSI-L), 45 GC samples that were microsatellite stable (MSS), 33 CRC samples with MSI-H, 15 CRC samples with MSI-L, and 45 CRC samples that were MSS.

Stage : -

Single-strand conformation polymorphism (SSCP) and DNA sequencing were used for the analysis.Frameshift Mutation-Somatic frameshit mutations of the KNTC1, ZC3H13, CENPH, TOPBP1, NDCO80 , RIF1, and NBS1 genes in the cancers with MSI-H.


Gene Details



NC_000013.10 (46528600..46626896, complement)

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Gene Type protein coding
Gene Family Zinc fingers, CCCH-type domain containing
Description -  
Chromosome 13
Location 13q14.11
Start 46528600  
End 46626896  
Strand -  
Gene Sequence

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Length 98297  
OMIM ID -   
HGNC ID HGNC:20368   
Unigene ID Hs.136102   
Ensembl ID ENSG00000123200   
PharmGKB ID PA134907656   

mRNA Information


mRNA ID ?NM_015070.4
Exon  
mRNA Sequence

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Length  



CDS Information


   
Location
CDS Sequence

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CCDS ID CCDS9400.1



Protein Information


      
Protein IDNP_055885.3
Protein Namezinc finger CCCH-type containing 13
Molecular Wt. (Da)0
Protein Sequence

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Length 1668  
Uniprot IDQ9NR97
Ensembl Protein ID ENSP00000218032  



Post-translational Modification Information (Source : HPRD)


Residue Type site
SPhosphorylation207
SPhosphorylation209
SPhosphorylation242
TPhosphorylation263
SPhosphorylation265
SPhosphorylation198;-
SPhosphorylation877;-
SPhosphorylation1230;-
SPhosphorylation1232;-
SPhosphorylation1056;-
SPhosphorylation581;-
SPhosphorylation1382;-
SPhosphorylation875;-
TPhosphorylation948;-
SPhosphorylation949;-
SPhosphorylation1409;-
TPhosphorylation1405;-
SPhosphorylation643;-
TPhosphorylation237;-
SPhosphorylation238;-
SPhosphorylation492;-
TPhosphorylation1318;-
SPhosphorylation993;-
SPhosphorylation356;-
SPhosphorylation358;-
SPhosphorylation1210;-
SPhosphorylation1213;-
SPhosphorylation110;-
SPhosphorylation316;-
TPhosphorylation317;-
SPhosphorylation325;-
TPhosphorylation1037;-
TPhosphorylation1038;-
TPhosphorylation105;-
SPhosphorylation108;-
SPhosphorylation109;-
SPhosphorylation1279;-
SPhosphorylation1288;-
SPhosphorylation380;-
SPhosphorylation372;-
SPhosphorylation381;-
SPhosphorylation77;-
SPhosphorylation64;-
SPhosphorylation318
TPhosphorylation354
YPhosphorylation359
TPhosphorylation364
SPhosphorylation370
SPhosphorylation831
SPhosphorylation833
SPhosphorylation837
SPhosphorylation845
SPhosphorylation848
SPhosphorylation853
YPhosphorylation851
SPhosphorylation986
SPhosphorylation1010
SPhosphorylation1014
SPhosphorylation1017
SPhosphorylation1453
SPhosphorylation1456
SPhosphorylation1466
TPhosphorylation984
SPhosphorylation241
SPhosphorylation1366
SPhosphorylation211
SPhosphorylation1208
SPhosphorylation328
SPhosphorylation1068
TPhosphorylation134
SPhosphorylation137
SPhosphorylation1065
TPhosphorylation1033
SPhosphorylation943
SPhosphorylation1438
SPhosphorylation204
YPhosphorylation374
SPhosphorylation621
TPhosphorylation985
TPhosphorylation1170
SPhosphorylation1191
SPhosphorylation1194
SPhosphorylation1364

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

No matching records from HPRD source could be found.

Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
pfam0064242-63  zf-CCCH
cl1159242-63  zf-CCCH superfamily
TIGR00934302-566  2a38euk
cl17365302-566  TrkH superfamily
smart0035642-63  ZnF_C3H1
PRK12678343-566  PRK12678
PRK12678344-558  PRK12678
PRK12678291-520  PRK12678
PRK12678370-580  PRK12678
TIGR01622470-573  SF-CC1
PRK12678315-520  PRK12678
TIGR01642382-490  U2AF_lg
TIGR01622392-508  SF-CC1
TIGR01642412-551  U2AF_lg
TIGR01622409-553  SF-CC1
TIGR01642471-605  U2AF_lg


Ontology Information


   
HPRD ID9709
Molecular ClassTranscription regulatory protein
Molecular FunctionMolecular function unknown (GO:0005554)
Biological ProcessBiological_process unknown (GO:0000004)  



SNP Information


View SNP Geneview Report   

Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO