Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| ABCC2 | 1244 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | 10 | DJS, MRP2, cMRP |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 25793771 | 2015 | Cell line : - Source : The KAM cohort is based on the screening group of the Norwegian Colorectal Cancer Prevention study in Telemark, and enriched by a series of clinical CRC cases operated at Telemark Hospital (Skien) and Oslo University Hospital. Sample Type : - No. of Sample : - Stage : - | real time RT-PCR | Up-regulation | - | This study found that ABCC2 and ABCG2 expression levels were altered already in mild/moderate dysplasia in carcinogenesis suggesting that these ABC transporters are involved in the early steps of carcinogenesis |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | ATP binding cassette transporters / subfamily C |
| Description | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. [provided by RefSeq, Jul 2008] |
| Chromosome | 10 |
| Location | 10q24 |
| Start | 101542457 |
| End | 101611662 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 69206 |
| OMIM ID | 601107 |
| HGNC ID | HGNC:53 |
| Unigene ID | Hs.368243 |
| Ensembl ID | ENSG00000023839 |
| PharmGKB ID | PA116 |
mRNA Information
| mRNA ID | NM_000392.4 |
|---|---|
| Exon | join(1..280,2011..2184,9637..9762,10954..11088, 11295..11402,11816..11871,14500..14734,16610..16773, 17789..17966,21422..21676,22785..22850,24787..24924, 25486..25632,27537..27621,28939..29005,30421..30547, 34711..34887,36193..36360,36492..36672,47710..47836, 48119..48254,49014..49233,49380..49534,51783..51938, 53494..53693,59370..59496,61202..61303,61725..61868, 63027..63185,64364..64530,68005..68199,68905..69595) | mRNA Sequence | Download Select all |
| Length | 5446 |
Protein Information
| Protein ID | NP_000383.1 |
|---|---|
| Protein Name | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| Molecular Wt. (Da) | 174061 |
| Protein Sequence | Download Select all |
| Length | 1545 |
| Uniprot ID | Q96BI1 |
| Ensembl Protein ID | ENSP00000311139 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 283 |
| T | Phosphorylation | 873 |
| S | Phosphorylation | 878 |
| Y | Phosphorylation | 885 |
| S | Phosphorylation | 900 |
| Y | Phosphorylation | 616 |
| S | Phosphorylation | 602 |
| S | Phosphorylation | 609 |
| S | Phosphorylation | 938 |
| T | Phosphorylation | 723 |
| T | Phosphorylation | 1378 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 821 | CANX | 252 | NP_001737.1 | in vivo | 12222674 |
| 5962 | RDX | 1534 | NP_002897.1 | in vitro | 12068294 |
| 79849 | PDZD3 | 6191 | NP_079067.2 | in vitro | 12615054 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| ABC transporters | hsa02010 |
| Bile secretion | hsa04976 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd03244 | 1298-1518 | ABCC_MRP_domain2 |
| cl21455 | 1298-1518 | P-loop_NTPase superfamily |
| cd03250 | 637-838 | ABCC_MRP_domain1 |
| cl21455 | 637-838 | P-loop_NTPase superfamily |
| cd03369 | 1294-1518 | ABCC_NFT1 |
| cd03288 | 1298-1528 | ABCC_SUR2 |
| cd03254 | 1298-1526 | ABCC_Glucan_exporter_like |
| cd03251 | 1300-1522 | ABCC_MsbA |
| cd03253 | 1300-1531 | ABCC_ATM1_transporter |
| cd03290 | 637-838 | ABCC_SUR1_N |
| cd03249 | 1300-1535 | ABC_MTABC3_MDL1_MDL2 |
| cd03228 | 1300-1511 | ABCC_MRP_Like |
| cd03252 | 1300-1531 | ABCC_Hemolysin |
| cd03291 | 654-862 | ABCC_CFTR1 |
| cd03245 | 1298-1513 | ABCC_bacteriocin_exporters |
| cd03289 | 1298-1522 | ABCC_CFTR2 |
| cd03248 | 1297-1512 | ABCC_TAP |
| cd03251 | 639-857 | ABCC_MsbA |
| cd03254 | 638-853 | ABCC_Glucan_exporter_like |
| cd03228 | 637-837 | ABCC_MRP_Like |
| cd03253 | 638-857 | ABCC_ATM1_transporter |
| cd03245 | 638-843 | ABCC_bacteriocin_exporters |
| cd03249 | 655-860 | ABC_MTABC3_MDL1_MDL2 |
| pfam00664 | 322-593 | ABC_membrane |
| cl00549 | 322-593 | ABC_membrane superfamily |
| cd03246 | 1300-1512 | ABCC_Protease_Secretion |
| pfam00664 | 976-1256 | ABC_membrane |
| cl00549 | 976-1256 | ABC_membrane superfamily |
| cd03247 | 1300-1516 | ABCC_cytochrome_bd |
| cd03244 | 637-844 | ABCC_MRP_domain2 |
| cd03235 | 654-840 | ABC_Metallic_Cations |
| cd03252 | 639-856 | ABCC_Hemolysin |
| cd03246 | 643-839 | ABCC_Protease_Secretion |
| pfam00005 | 1317-1465 | ABC_tran |
| cd03293 | 637-841 | ABC_NrtD_SsuB_transporters |
| cd03257 | 1300-1516 | ABC_NikE_OppD_transporters |
| cd03261 | 1316-1528 | ABC_Org_Solvent_Resistant |
| cd03225 | 1301-1511 | ABC_cobalt_CbiO_domain1 |
| cd00267 | 1306-1511 | ABC_ATPase |
| cd03214 | 1316-1516 | ABC_Iron-Siderophores_B12_Hemin |
| cd03225 | 638-838 | ABC_cobalt_CbiO_domain1 |
| cd03299 | 1314-1540 | ABC_ModC_like |
| pfam00005 | 654-789 | ABC_tran |
| cd03247 | 637-843 | ABCC_cytochrome_bd |
| cd03214 | 654-843 | ABC_Iron-Siderophores_B12_Hemin |
| cd03219 | 1316-1520 | ABC_Mj1267_LivG_branched |
| cd03258 | 1316-1526 | ABC_MetN_methionine_transporter |
| cd03260 | 1316-1521 | ABC_PstB_phosphate_transporter |
| cd03259 | 649-843 | ABC_Carb_Solutes_like |
| cd03256 | 1300-1521 | ABC_PhnC_transporter |
| cd03250 | 1300-1511 | ABCC_MRP_domain1 |
| cd03229 | 1316-1511 | ABC_Class3 |
| cd03257 | 654-843 | ABC_NikE_OppD_transporters |
| cd03255 | 643-839 | ABC_MJ0796_LolCDE_FtsE |
| cd03259 | 1316-1516 | ABC_Carb_Solutes_like |
| cd00267 | 638-838 | ABC_ATPase |
| cd03224 | 1316-1523 | ABC_TM1139_LivF_branched |
| cd03261 | 655-850 | ABC_Org_Solvent_Resistant |
| cd03235 | 1301-1512 | ABC_Metallic_Cations |
| cd03260 | 643-844 | ABC_PstB_phosphate_transporter |
| cd03230 | 654-839 | ABC_DR_subfamily_A |
| cd03263 | 1308-1521 | ABC_subfamily_A |
| cd03229 | 654-838 | ABC_Class3 |
| cd03248 | 638-839 | ABCC_TAP |
| cd03295 | 639-850 | ABC_OpuCA_Osmoprotection |
| cd03230 | 1316-1512 | ABC_DR_subfamily_A |
| cd03216 | 1316-1513 | ABC_Carb_Monos_I |
| cd03292 | 1300-1512 | ABC_FtsE_transporter |
| cd03258 | 654-851 | ABC_MetN_methionine_transporter |
| cd03262 | 655-839 | ABC_HisP_GlnQ |
| cd03226 | 643-840 | ABC_cobalt_CbiO_domain2 |
| cd03299 | 650-843 | ABC_ModC_like |
| cd03262 | 1300-1512 | ABC_HisP_GlnQ |
| cd03255 | 1316-1512 | ABC_MJ0796_LolCDE_FtsE |
| cd03224 | 654-850 | ABC_TM1139_LivF_branched |
| cd03294 | 1332-1525 | ABC_Pro_Gly_Betaine |
| cd03369 | 649-844 | ABCC_NFT1 |
| cd03301 | 653-843 | ABC_MalK_N |
| cd03296 | 654-844 | ABC_CysA_sulfate_importer |
| cd03264 | 1300-1516 | ABC_drug_resistance_like |
| cd03294 | 635-836 | ABC_Pro_Gly_Betaine |
| cd03256 | 645-848 | ABC_PhnC_transporter |
| cd03297 | 656-843 | ABC_ModC_molybdenum_transporter |
| cd03226 | 1315-1513 | ABC_cobalt_CbiO_domain2 |
| cd03223 | 1300-1494 | ABCD_peroxisomal_ALDP |
| cd03288 | 637-861 | ABCC_SUR2 |
| cd03220 | 654-843 | ABC_KpsT_Wzt |
| cd03216 | 654-840 | ABC_Carb_Monos_I |
| cd03263 | 654-848 | ABC_subfamily_A |
| cd03268 | 1316-1514 | ABC_BcrA_bacitracin_resist |
| cd03300 | 647-844 | ABC_PotA_N |
| cd03298 | 1322-1516 | ABC_ThiQ_thiamine_transporter |
| cd03268 | 654-843 | ABC_BcrA_bacitracin_resist |
| cd03295 | 1300-1527 | ABC_OpuCA_Osmoprotection |
| cd03234 | 656-794 | ABCG_White |
| cd03298 | 656-843 | ABC_ThiQ_thiamine_transporter |
| cd03289 | 637-865 | ABCC_CFTR2 |
| cd03293 | 1300-1514 | ABC_NrtD_SsuB_transporters |
| cd03213 | 1316-1516 | ABCG_EPDR |
| cd03266 | 1300-1516 | ABC_NatA_sodium_exporter |
| cd03219 | 654-850 | ABC_Mj1267_LivG_branched |
| cd03218 | 1316-1523 | ABC_YhbG |
| cd03265 | 1317-1521 | ABC_DrrA |
| TIGR01189 | 1314-1486 | ccmA |
| cd03290 | 1317-1510 | ABCC_SUR1_N |
| cd03218 | 654-792 | ABC_YhbG |
| cd03292 | 637-820 | ABC_FtsE_transporter |
| cd03223 | 649-792 | ABCD_peroxisomal_ALDP |
| cd03215 | 1313-1512 | ABC_Carb_Monos_II |
| cd03213 | 654-843 | ABCG_EPDR |
| cd03221 | 638-838 | ABCF_EF-3 |
| cd03297 | 1328-1513 | ABC_ModC_molybdenum_transporter |
| cd03220 | 1316-1516 | ABC_KpsT_Wzt |
| cd03217 | 654-853 | ABC_FeS_Assembly |
| cd03265 | 649-844 | ABC_DrrA |
| cd03296 | 1317-1530 | ABC_CysA_sulfate_importer |
| cd03300 | 1314-1525 | ABC_PotA_N |
| cd03269 | 654-843 | ABC_putative_ATPase |
| cd03264 | 654-843 | ABC_drug_resistance_like |
| TIGR01189 | 645-828 | ccmA |
| cd03215 | 652-839 | ABC_Carb_Monos_II |
| cd03267 | 1316-1513 | ABC_NatA_like |
| cd03231 | 645-793 | ABC_CcmA_heme_exporter |
| cd03217 | 1316-1524 | ABC_FeS_Assembly |
| cd03267 | 644-843 | ABC_NatA_like |
| cd03266 | 654-843 | ABC_NatA_sodium_exporter |
| cd03301 | 1316-1516 | ABC_MalK_N |
| cd03269 | 1300-1513 | ABC_putative_ATPase |
| cd03234 | 1315-1516 | ABCG_White |
| cd03291 | 1302-1521 | ABCC_CFTR1 |
| cd03237 | 660-864 | ABC_RNaseL_inhibitor_domain2 |
| cd03271 | 654-844 | ABC_UvrA_II |
| cd03231 | 1316-1486 | ABC_CcmA_heme_exporter |
| cd03222 | 660-853 | ABC_RNaseL_inhibitor |
| cd03237 | 1323-1508 | ABC_RNaseL_inhibitor_domain2 |
| cd03221 | 1300-1511 | ABCF_EF-3 |
| cd03238 | 654-838 | ABC_UvrA |
| cd03227 | 648-834 | ABC_Class2 |
| PRK13540 | 646-820 | PRK13540 |
| pfam01926 | 1329-1420 | MMR_HSR1 |
| cd01131 | 666-704 | PilT |
| cd00880 | 668-693 | Era_like |
| cd03232 | 656-793 | ABCG_PDR_domain2 |
| TIGR00957 | 8-1537 | MRP_assoc_pro |
| PLN03130 | 198-1523 | PLN03130 |
| PLN03232 | 23-1539 | PLN03232 |
| PTZ00243 | 310-1521 | PTZ00243 |
| TIGR01271 | 198-1522 | CFTR_protein |
| COG1132 | 970-1534 | MdlB |
| COG2274 | 961-1529 | SunT |
| COG1132 | 310-857 | MdlB |
| TIGR02203 | 1030-1522 | MsbA_lipidA |
| TIGR02204 | 1056-1529 | MsbA_rel |
| PRK10790 | 1029-1531 | PRK10790 |
| COG2274 | 304-857 | SunT |
| COG4988 | 1051-1534 | CydD |
| TIGR00958 | 1031-1531 | 3a01208 |
| TIGR01846 | 1056-1531 | type_I_sec_HlyB |
| COG4987 | 1077-1531 | CydC |
| COG5265 | 1049-1526 | ATM1 |
| PRK13657 | 1106-1537 | PRK13657 |
| TIGR03375 | 1267-1523 | type_I_sec_LssB |
| TIGR03797 | 1065-1533 | NHLM_micro_ABC2 |
| TIGR01193 | 1061-1529 | bacteriocin_ABC |
| PRK11176 | 1056-1522 | PRK11176 |
| TIGR01192 | 1110-1537 | chvA |
| COG4988 | 361-861 | CydD |
| PRK11174 | 1328-1531 | PRK11174 |
| TIGR03796 | 1059-1528 | NHLM_micro_ABC1 |
| TIGR03375 | 448-851 | type_I_sec_LssB |
| TIGR02857 | 1285-1507 | CydD |
| TIGR02868 | 1077-1495 | CydC |
| PRK11174 | 657-869 | PRK11174 |
| PRK11160 | 1266-1529 | PRK11160 |
| TIGR02203 | 340-856 | MsbA_lipidA |
| TIGR02857 | 636-834 | CydD |
| COG4987 | 391-855 | CydC |
| TIGR01193 | 504-857 | bacteriocin_ABC |
| PRK11160 | 636-857 | PRK11160 |
| TIGR02204 | 654-857 | MsbA_rel |
| COG1131 | 1300-1523 | CcmA |
| TIGR01846 | 417-857 | type_I_sec_HlyB |
| COG1121 | 649-840 | ZnuC |
| PTZ00265 | 754-1529 | PTZ00265 |
| PRK10789 | 1265-1526 | PRK10789 |
| COG1120 | 1300-1523 | FepC |
| COG1135 | 1300-1525 | AbcC |
| PRK13657 | 622-878 | PRK13657 |
| TIGR01842 | 653-851 | type_I_sec_PrtD |
| PRK11176 | 637-857 | PRK11176 |
| PRK10789 | 643-853 | PRK10789 |
| COG5265 | 445-857 | ATM1 |
| TIGR02868 | 639-821 | CydC |
| TIGR03797 | 334-856 | NHLM_micro_ABC2 |
| TIGR01842 | 1316-1523 | type_I_sec_PrtD |
| TIGR00958 | 333-856 | 3a01208 |
| COG1122 | 1300-1523 | EcfA2 |
| TIGR01192 | 632-861 | chvA |
| COG4618 | 1316-1523 | ArpD |
| PRK10790 | 503-855 | PRK10790 |
| COG4618 | 653-851 | ArpD |
| TIGR03796 | 654-857 | NHLM_micro_ABC1 |
| COG1121 | 1300-1523 | ZnuC |
| COG1124 | 1300-1525 | DppF |
| COG1123 | 1315-1525 | GsiA |
| COG1116 | 654-841 | TauB |
| COG1122 | 643-852 | EcfA2 |
| COG1136 | 655-842 | LolD |
| COG4525 | 637-842 | TauB |
| TIGR00968 | 654-844 | 3a0106s01 |
| COG1131 | 654-901 | CcmA |
| COG1120 | 654-844 | FepC |
| COG1129 | 1316-1513 | MglA |
| PRK13632 | 1300-1543 | cbiO |
| COG1118 | 652-844 | CysA |
| COG0411 | 1316-1525 | LivG |
| PTZ00265 | 1239-1509 | PTZ00265 |
| COG1123 | 1316-1525 | GsiA |
| COG0410 | 1316-1522 | LivF |
| TIGR03265 | 654-844 | PhnT2 |
| COG3839 | 1300-1525 | MalK |
| TIGR04520 | 1300-1523 | ECF_ATPase_1 |
| COG1123 | 654-844 | GsiA |
| COG3839 | 654-844 | MalK |
| COG3842 | 654-844 | PotA |
| COG1135 | 654-881 | AbcC |
| TIGR01186 | 1323-1525 | proV |
| COG1127 | 1316-1536 | MlaF |
| COG4608 | 654-850 | AppF |
| TIGR02315 | 1300-1521 | ABC_phnC |
| TIGR02142 | 1323-1536 | modC_ABC |
| COG1126 | 655-865 | GlnQ |
| PRK10070 | 1306-1529 | PRK10070 |
| COG1101 | 1311-1513 | PhnK |
| COG4608 | 1305-1522 | AppF |
| COG3840 | 658-853 | ThiQ |
| COG0444 | 1299-1525 | DppD |
| COG4178 | 1297-1494 | YddA |
| COG3638 | 1300-1521 | PhnC |
| PRK13637 | 1317-1520 | cbiO |
| TIGR00972 | 654-844 | 3a0107s01c2 |
| PRK10851 | 656-844 | PRK10851 |
| COG1126 | 1316-1522 | GlnQ |
| PRK11153 | 1300-1517 | metN |
| PRK11248 | 647-842 | tauB |
| COG1124 | 654-850 | DppF |
| TIGR02314 | 1331-1525 | ABC_MetN |
| COG1136 | 1316-1512 | LolD |
| COG4559 | 1316-1522 | COG4559 |
| COG0488 | 638-855 | Uup |
| TIGR01186 | 654-844 | proV |
| TIGR02315 | 654-848 | ABC_phnC |
| COG1123 | 654-851 | GsiA |
| PRK13650 | 1300-1521 | cbiO |
| COG1125 | 654-859 | OpuBA |
| PRK14250 | 1299-1525 | PRK14250 |
| PRK11264 | 657-850 | PRK11264 |
| PLN03232 | 418-876 | PLN03232 |
| PRK14244 | 1316-1525 | PRK14244 |
| TIGR04520 | 643-844 | ECF_ATPase_1 |
| COG3638 | 656-844 | PhnC |
| COG4555 | 654-854 | NatA |
| COG1127 | 655-850 | MlaF |
| COG1125 | 1300-1525 | OpuBA |
| COG4175 | 1317-1544 | ProV |
| TIGR00972 | 1316-1525 | 3a0107s01c2 |
| COG0410 | 654-850 | LivF |
| COG3842 | 1296-1525 | PotA |
| PRK15056 | 636-876 | PRK15056 |
| TIGR02314 | 654-866 | ABC_MetN |
| TIGR03258 | 654-848 | PhnT |
| PRK14246 | 1316-1525 | PRK14246 |
| TIGR01194 | 1027-1514 | cyc_pep_trnsptr |
| COG1134 | 655-844 | TagH |
| PRK14262 | 1300-1525 | PRK14262 |
| COG4619 | 654-804 | FetA |
| COG4555 | 1317-1522 | NatA |
| COG1117 | 654-844 | PstB |
| COG4172 | 1286-1525 | YejF |
| TIGR04521 | 1317-1523 | ECF_ATPase_2 |
| TIGR02769 | 1316-1514 | nickel_nikE |
| TIGR04521 | 656-860 | ECF_ATPase_2 |
| COG4167 | 1328-1525 | SapF |
| COG3845 | 1317-1521 | YufO |
| PRK13636 | 1317-1522 | cbiO |
| TIGR02142 | 656-887 | modC_ABC |
| PRK13648 | 1300-1521 | cbiO |
| PRK14239 | 653-822 | PRK14239 |
| TIGR03410 | 655-848 | urea_trans_UrtE |
| PRK14266 | 649-843 | PRK14266 |
| COG4175 | 654-851 | ProV |
| PRK11432 | 656-848 | fbpC |
| PRK14250 | 635-873 | PRK14250 |
| COG2884 | 1300-1520 | FtsE |
| TIGR03608 | 655-834 | L_ocin_972_ABC |
| TIGR01277 | 658-839 | thiQ |
| PRK13632 | 632-852 | cbiO |
| PRK14255 | 654-871 | PRK14255 |
| PRK13644 | 1300-1525 | cbiO |
| TIGR01166 | 1316-1492 | cbiO |
| TIGR03005 | 647-843 | ectoine_ehuA |
| COG4604 | 654-844 | CeuD |
| PRK14247 | 1299-1525 | PRK14247 |
| COG4148 | 656-887 | ModC |
| COG0488 | 655-852 | Uup |
| TIGR02982 | 656-840 | heterocyst_DevA |
| COG4559 | 656-844 | COG4559 |
| COG4615 | 1045-1514 | PvdE |
| PRK13635 | 643-867 | cbiO |
| PRK13539 | 655-794 | PRK13539 |
| PRK13640 | 634-844 | cbiO |
| TIGR01187 | 1332-1525 | potA |
| PRK13635 | 1299-1523 | cbiO |
| PRK14259 | 649-873 | PRK14259 |
| PRK13633 | 1315-1521 | PRK13633 |
| COG0444 | 654-849 | DppD |
| PRK11231 | 1316-1523 | fecE |
| TIGR04406 | 654-792 | LPS_export_lptB |
| COG1118 | 1299-1543 | CysA |
| PRK13640 | 1332-1538 | cbiO |
| PRK13642 | 1300-1522 | cbiO |
| PRK10771 | 658-850 | thiQ |
| PRK14257 | 613-843 | PRK14257 |
| PRK14243 | 654-873 | PRK14243 |
| PRK14251 | 1317-1525 | PRK14251 |
| PRK13548 | 1316-1523 | hmuV |
| PRK14240 | 655-851 | PRK14240 |
| COG1129 | 654-840 | MglA |
| TIGR03410 | 1316-1521 | urea_trans_UrtE |
| PRK09493 | 1300-1525 | glnQ |
| COG4148 | 1313-1525 | ModC |
| PRK14242 | 1295-1526 | PRK14242 |
| COG1134 | 1308-1524 | TagH |
| COG1117 | 1316-1525 | PstB |
| PRK09452 | 649-844 | potA |
| PRK13548 | 654-844 | hmuV |
| TIGR00968 | 1316-1531 | 3a0106s01 |
| PRK14263 | 654-823 | PRK14263 |
| PRK14254 | 648-841 | PRK14254 |
| PRK09493 | 656-865 | glnQ |
| PRK13648 | 632-843 | cbiO |
| PRK13652 | 1316-1525 | cbiO |
| TIGR01187 | 669-844 | potA |
| PRK13646 | 637-857 | cbiO |
| PRK15079 | 1319-1525 | PRK15079 |
| TIGR01188 | 1317-1521 | drrA |
| COG0488 | 1300-1513 | Uup |
| PRK14258 | 1300-1498 | PRK14258 |
| COG0411 | 654-850 | LivG |
| COG1116 | 1316-1514 | TauB |
| PRK13641 | 1300-1521 | cbiO |
| PRK14244 | 648-844 | PRK14244 |
| TIGR03415 | 654-868 | ABC_choXWV_ATP |
| PRK14272 | 654-849 | PRK14272 |
| PRK09536 | 1316-1522 | btuD |
| PRK14240 | 1297-1525 | PRK14240 |
| COG3840 | 1321-1522 | ThiQ |
| COG4161 | 650-865 | ArtP |
| TIGR03258 | 1298-1540 | PhnT |
| COG4598 | 655-843 | HisP |
| COG4619 | 1306-1525 | FetA |
| COG4172 | 644-859 | YejF |
| COG1137 | 654-792 | LptB |
| PRK14242 | 649-854 | PRK14242 |
| COG1137 | 1316-1525 | LptB |
| COG4133 | 647-838 | CcmA |
| TIGR03873 | 1315-1522 | F420-0_ABC_ATP |
| COG2884 | 655-845 | FtsE |
| PRK14266 | 1316-1525 | PRK14266 |
| PRK14245 | 1317-1526 | PRK14245 |
| PRK11231 | 654-844 | fecE |
| TIGR04406 | 1316-1522 | LPS_export_lptB |
| PRK11153 | 654-844 | metN |
| COG4167 | 654-850 | SapF |
| PRK11607 | 645-845 | potG |
| COG4181 | 655-841 | YbbA |
| PRK13634 | 656-858 | cbiO |
| TIGR01288 | 654-849 | nodI |
| PRK14251 | 657-849 | PRK14251 |
| PLN03130 | 657-868 | PLN03130 |
| TIGR03864 | 1316-1523 | PQQ_ABC_ATP |
| PRK14265 | 656-843 | PRK14265 |
| COG4615 | 318-841 | PvdE |
| PRK11247 | 655-793 | ssuB |
| PRK14258 | 643-843 | PRK14258 |
| COG4178 | 623-792 | YddA |
| TIGR03269 | 1316-1521 | met_CoM_red_A2 |
| PRK14269 | 1320-1525 | PRK14269 |
| PRK10744 | 655-792 | pstB |
| COG1101 | 649-840 | PhnK |
| PRK14248 | 1320-1525 | PRK14248 |
| PRK15439 | 1316-1521 | PRK15439 |
| PRK14236 | 649-822 | PRK14236 |
| PRK10419 | 1316-1514 | nikE |
| TIGR01188 | 654-853 | drrA |
| COG4172 | 1316-1525 | YejF |
| PRK11000 | 655-843 | PRK11000 |
| TIGR02211 | 657-841 | LolD_lipo_ex |
| PRK14262 | 643-851 | PRK14262 |
| PRK14274 | 654-841 | PRK14274 |
| PRK13638 | 1308-1522 | cbiO |
| PRK14267 | 654-843 | PRK14267 |
| TIGR03771 | 659-849 | anch_rpt_ABC |
| TIGR03005 | 1300-1525 | ectoine_ehuA |
| PRK09536 | 654-849 | btuD |
| TIGR03269 | 1319-1522 | met_CoM_red_A2 |
| PRK13637 | 656-844 | cbiO |
| PRK14268 | 1317-1525 | PRK14268 |
| PRK14255 | 1317-1545 | PRK14255 |
| PRK10247 | 656-834 | PRK10247 |
| PRK14235 | 649-822 | PRK14235 |
| PRK14253 | 654-848 | PRK14253 |
| TIGR01277 | 1328-1512 | thiQ |
| PRK13536 | 642-849 | PRK13536 |
| PRK14254 | 1317-1525 | PRK14254 |
| PRK15112 | 632-850 | PRK15112 |
| PRK10895 | 1316-1523 | PRK10895 |
| PRK13644 | 649-850 | cbiO |
| PRK14272 | 1331-1525 | PRK14272 |
| PRK14257 | 1293-1525 | PRK14257 |
| PRK13647 | 634-860 | cbiO |
| TIGR03873 | 645-849 | F420-0_ABC_ATP |
| PRK14270 | 646-873 | PRK14270 |
| PTZ00265 | 704-860 | PTZ00265 |
| TIGR00954 | 654-801 | 3a01203 |
| TIGR02673 | 638-828 | FtsE |
| TIGR01184 | 1317-1527 | ntrCD |
| PRK14261 | 648-873 | PRK14261 |
| PRK10771 | 1328-1523 | thiQ |
| PRK13639 | 643-844 | cbiO |
| PRK09984 | 657-844 | PRK09984 |
| PRK10070 | 632-864 | PRK10070 |
| PRK14270 | 1332-1525 | PRK14270 |
| TIGR02769 | 643-860 | nickel_nikE |
| PRK11300 | 1315-1525 | livG |
| PRK14241 | 654-822 | PRK14241 |
| PRK11607 | 1328-1525 | potG |
| PRK10619 | 647-850 | PRK10619 |
| PRK15112 | 1330-1525 | PRK15112 |
| PTZ00243 | 1308-1525 | PTZ00243 |
| PRK14264 | 1314-1525 | PRK14264 |
| PRK14275 | 649-849 | PRK14275 |
| PRK11247 | 1316-1512 | ssuB |
| PRK14267 | 1316-1525 | PRK14267 |
| PRK11124 | 656-865 | artP |
| PRK13643 | 1300-1523 | cbiO |
| PRK13645 | 632-844 | cbiO |
| PRK10261 | 1320-1525 | PRK10261 |
| PRK13639 | 1307-1521 | cbiO |
| PRK13539 | 1314-1480 | PRK13539 |
| TIGR02770 | 1330-1526 | nickel_nikD |
| PRK14260 | 1317-1525 | PRK14260 |
| PRK10535 | 643-840 | PRK10535 |
| TIGR01184 | 654-837 | ntrCD |
| COG1129 | 606-840 | MglA |
| PRK10535 | 1316-1513 | PRK10535 |
| PRK14249 | 1316-1525 | PRK14249 |
| PRK14245 | 646-873 | PRK14245 |
| PRK13537 | 654-850 | PRK13537 |
| PRK14261 | 1317-1526 | PRK14261 |
| COG0396 | 654-843 | SufC |
| TIGR02211 | 1316-1514 | LolD_lipo_ex |
| PRK10419 | 622-841 | nikE |
| TIGR02770 | 654-844 | nickel_nikD |
| PRK14238 | 646-841 | PRK14238 |
| COG1129 | 1328-1512 | MglA |
| PRK13642 | 634-870 | cbiO |
| PRK13651 | 656-848 | PRK13651 |
| TIGR00954 | 1274-1494 | 3a01203 |
| TIGR02633 | 1328-1512 | xylG |
| COG0488 | 1277-1493 | Uup |
| PRK10762 | 1333-1513 | PRK10762 |
| PRK14264 | 645-843 | PRK14264 |
| PRK14239 | 1317-1525 | PRK14239 |
| PRK14271 | 1332-1525 | PRK14271 |
| TIGR03864 | 654-853 | PQQ_ABC_ATP |
| PRK13537 | 1300-1523 | PRK13537 |
| PRK14253 | 1317-1525 | PRK14253 |
| PRK11629 | 654-823 | lolD |
| TIGR02673 | 1300-1511 | FtsE |
| PRK11308 | 1305-1525 | dppF |
| PRK13536 | 1316-1522 | PRK13536 |
| PRK14252 | 654-851 | PRK14252 |
| PRK14247 | 654-843 | PRK14247 |
| PRK11614 | 657-850 | livF |
| COG4586 | 647-853 | COG4586 |
| COG4136 | 637-826 | YnjD |
| PRK13633 | 643-844 | PRK13633 |
| PRK14260 | 632-792 | PRK14260 |
| COG1119 | 656-831 | ModF |
| PRK13549 | 1328-1512 | PRK13549 |
| TIGR03719 | 655-852 | ABC_ABC_ChvD |
| TIGR03771 | 1328-1522 | anch_rpt_ABC |
| PRK09700 | 1317-1510 | PRK09700 |
| PRK11264 | 1316-1525 | PRK11264 |
| PRK10744 | 1290-1525 | pstB |
| COG4133 | 1314-1474 | CcmA |
| PRK13549 | 1317-1513 | PRK13549 |
| PRK15439 | 1318-1512 | PRK15439 |
| TIGR03608 | 1316-1475 | L_ocin_972_ABC |
| COG4604 | 1306-1523 | CeuD |
| PRK14235 | 1317-1525 | PRK14235 |
| COG4181 | 1316-1514 | YbbA |
| PRK14268 | 646-823 | PRK14268 |
| TIGR03522 | 1316-1523 | GldA_ABC_ATP |
| COG4586 | 1307-1527 | COG4586 |
| PRK14237 | 1333-1525 | PRK14237 |
| PRK14252 | 1295-1525 | PRK14252 |
| PRK09473 | 1328-1525 | oppD |
| PRK09544 | 1316-1519 | znuC |
| PRK10895 | 654-792 | PRK10895 |
| TIGR01288 | 1315-1523 | nodI |
| PRK13643 | 637-846 | cbiO |
| PRK14249 | 654-792 | PRK14249 |
| PRK15134 | 1316-1529 | PRK15134 |
| PRK14248 | 654-843 | PRK14248 |
| PRK10247 | 1332-1507 | PRK10247 |
| TIGR01257 | 1333-1544 | rim_protein |
| PRK10522 | 575-841 | PRK10522 |
| COG1119 | 1285-1513 | ModF |
| PRK10619 | 1316-1525 | PRK10619 |
| COG4152 | 654-881 | YhaQ |
| PRK14246 | 649-844 | PRK14246 |
| PRK11614 | 1316-1513 | livF |
| COG3845 | 1317-1520 | YufO |
| PRK10261 | 1328-1525 | PRK10261 |
| PRK10575 | 1331-1523 | PRK10575 |
| COG4598 | 1316-1525 | HisP |
| PRK14256 | 654-843 | PRK14256 |
| PRK14236 | 1316-1525 | PRK14236 |
| TIGR03740 | 1315-1513 | galliderm_ABC |
| TIGR01257 | 654-836 | rim_protein |
| TIGR02324 | 654-793 | CP_lyasePhnL |
| PRK13650 | 643-889 | cbiO |
| PRK14275 | 1317-1525 | PRK14275 |
| COG4138 | 1300-1525 | BtuD |
| PRK10851 | 1316-1525 | PRK10851 |
| TIGR00955 | 664-844 | 3a01204 |
| PRK13634 | 1300-1525 | cbiO |
| COG0396 | 1316-1524 | SufC |
| PRK14256 | 1299-1525 | PRK14256 |
| PRK10522 | 1289-1514 | PRK10522 |
| PRK13645 | 1332-1541 | cbiO |
| TIGR01194 | 657-841 | cyc_pep_trnsptr |
| PRK14273 | 654-861 | PRK14273 |
| TIGR01978 | 655-853 | sufC |
| PRK11432 | 1325-1545 | fbpC |
| COG4172 | 643-850 | YejF |
| TIGR03265 | 1301-1528 | PhnT2 |
| TIGR02982 | 1316-1512 | heterocyst_DevA |
| TIGR02323 | 1318-1525 | CP_lyasePhnK |
| PRK13646 | 1299-1521 | cbiO |
| PRK14238 | 1296-1525 | PRK14238 |
| PRK11144 | 656-792 | modC |
| COG3845 | 655-840 | YufO |
| PRK11144 | 1313-1520 | modC |
| PRK13409 | 661-790 | PRK13409 |
| TIGR03269 | 645-862 | met_CoM_red_A2 |
| PRK14273 | 1331-1545 | PRK14273 |
| PRK13538 | 655-794 | PRK13538 |
| PRK15439 | 657-844 | PRK15439 |
| PRK14265 | 1315-1496 | PRK14265 |
| PRK10253 | 643-844 | PRK10253 |
| PRK13641 | 656-852 | cbiO |
| TIGR02633 | 1315-1513 | xylG |
| COG4161 | 1316-1517 | ArtP |
| PRK14243 | 1315-1525 | PRK14243 |
| COG1245 | 660-833 | Rli1 |
| COG4152 | 1316-1544 | YhaQ |
| PRK11650 | 645-793 | ugpC |
| COG4674 | 1332-1521 | COG4674 |
| PRK14259 | 1317-1495 | PRK14259 |
| PRK10253 | 1332-1522 | PRK10253 |
| PRK03695 | 1321-1522 | PRK03695 |
| PRK11308 | 651-851 | dppF |
| PRK10261 | 654-848 | PRK10261 |
| PRK11000 | 1318-1525 | PRK11000 |
| PRK13543 | 645-828 | PRK13543 |
| PRK14237 | 649-822 | PRK14237 |
| PRK14274 | 1317-1525 | PRK14274 |
| PRK13631 | 1332-1521 | cbiO |
| PRK09544 | 656-834 | znuC |
| PRK13631 | 656-844 | cbiO |
| TIGR03415 | 1319-1525 | ABC_choXWV_ATP |
| PRK13649 | 1317-1523 | cbiO |
| PRK13647 | 1300-1522 | cbiO |
| PRK10575 | 663-849 | PRK10575 |
| PRK14263 | 1331-1525 | PRK14263 |
| PRK09452 | 1316-1540 | potA |
| TIGR03411 | 654-844 | urea_trans_UrtD |
| PRK10418 | 654-850 | nikD |
| PRK10982 | 1332-1513 | PRK10982 |
| PRK09580 | 649-854 | sufC |
| PRK14269 | 656-823 | PRK14269 |
| PRK11124 | 1316-1516 | artP |
| PRK10584 | 657-841 | PRK10584 |
| PRK15079 | 654-848 | PRK15079 |
| PRK13538 | 1315-1508 | PRK13538 |
| PRK13652 | 643-844 | cbiO |
| PRK09984 | 1317-1521 | PRK09984 |
| PLN03073 | 637-839 | PLN03073 |
| PRK09700 | 654-843 | PRK09700 |
| TIGR03522 | 651-850 | GldA_ABC_ATP |
| COG3845 | 654-840 | YufO |
| PRK11288 | 1331-1514 | araG |
| PRK15064 | 649-787 | PRK15064 |
| PRK13547 | 1316-1523 | hmuV |
| COG2401 | 655-841 | MK0520 |
| PRK15134 | 762-850 | PRK15134 |
| PRK14271 | 608-857 | PRK14271 |
| TIGR02323 | 655-843 | CP_lyasePhnK |
| smart00382 | 664-825 | AAA |
| PRK13545 | 656-857 | tagH |
| COG4778 | 654-793 | PhnL |
| PRK13636 | 634-852 | cbiO |
| TIGR00955 | 1308-1523 | 3a01204 |
| PRK14241 | 1333-1525 | PRK14241 |
| TIGR03411 | 1423-1521 | urea_trans_UrtD |
| PRK09700 | 1328-1514 | PRK09700 |
| PRK10908 | 646-822 | PRK10908 |
| TIGR00630 | 754-844 | uvra |
| PRK10982 | 1317-1524 | PRK10982 |
| PLN03073 | 762-858 | PLN03073 |
| TIGR00956 | 1328-1530 | 3a01205 |
| PRK13409 | 1328-1508 | PRK13409 |
| PRK10908 | 1317-1512 | PRK10908 |
| smart00382 | 1328-1510 | AAA |
| COG1245 | 1328-1522 | Rli1 |
| PRK10584 | 1316-1514 | PRK10584 |
| COG0178 | 761-864 | UvrA |
| PRK11147 | 654-706 | PRK11147 |
| COG0178 | 1437-1526 | UvrA |
| PRK15134 | 761-850 | PRK15134 |
| PRK15134 | 1308-1525 | PRK15134 |
| TIGR00956 | 1304-1510 | 3a01205 |
| TIGR01257 | 608-822 | rim_protein |
| PRK11701 | 655-696 | phnK |
| PRK03695 | 657-792 | PRK03695 |
| PRK10762 | 1328-1512 | PRK10762 |
| PLN03211 | 1316-1511 | PLN03211 |
| PRK13651 | 1316-1522 | PRK13651 |
| TIGR02633 | 657-793 | xylG |
| TIGR00630 | 1437-1521 | uvra |
| PRK15093 | 1437-1525 | PRK15093 |
Ontology Information
| HPRD ID | 3685 |
|---|---|
| Molecular Class | Transport/cargo protein |
| Molecular Function | Transcription regulator activity (GO:0030528); DNA binding (GO:0003677) |
| Biological Process | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219) |
Drug Information
| Uniprot ID | DrugBank ID | Name | Type |
|---|---|---|---|
| Q92887 | DB00171 | Adenosine triphosphate | SmallMoleculeDrug |
| Q92887 | DB01138 | Sulfinpyrazone | SmallMoleculeDrug |
| Q92887 | DB00067 | Vasopressin | BiotechDrug |
| Q92887 | DB00091 | Cyclosporine | SmallMoleculeDrug |
| Q92887 | DB00116 | Tetrahydrofolic acid | SmallMoleculeDrug |
| Q92887 | DB00143 | Glutathione | SmallMoleculeDrug |
| Q92887 | DB00175 | Pravastatin | SmallMoleculeDrug |
| Q92887 | DB00206 | Reserpine | SmallMoleculeDrug |
| Q92887 | DB00224 | Indinavir | SmallMoleculeDrug |
| Q92887 | DB00227 | Lovastatin | SmallMoleculeDrug |
| Q92887 | DB00252 | Phenytoin | SmallMoleculeDrug |
| Q92887 | DB00257 | Clotrimazole | SmallMoleculeDrug |
| Q92887 | DB00275 | Olmesartan | SmallMoleculeDrug |
| Q92887 | DB00286 | Conjugated Estrogens | SmallMoleculeDrug |
| Q92887 | DB00300 | Tenofovir | SmallMoleculeDrug |
| Q92887 | DB00328 | Indomethacin | SmallMoleculeDrug |
| Q92887 | DB00345 | Aminohippurate | SmallMoleculeDrug |
| Q92887 | DB00398 | Sorafenib | SmallMoleculeDrug |
| Q92887 | DB00421 | Spironolactone | SmallMoleculeDrug |
| Q92887 | DB00503 | Ritonavir | SmallMoleculeDrug |
| Q92887 | DB00515 | Cisplatin | SmallMoleculeDrug |
| Q92887 | DB00526 | Oxaliplatin | SmallMoleculeDrug |
| Q92887 | DB00541 | Vincristine | SmallMoleculeDrug |
| Q92887 | DB00563 | Methotrexate | SmallMoleculeDrug |
| Q92887 | DB00564 | Carbamazepine | SmallMoleculeDrug |
| Q92887 | DB00570 | Vinblastine | SmallMoleculeDrug |
| Q92887 | DB00602 | Ivermectin | SmallMoleculeDrug |
| Q92887 | DB00641 | Simvastatin | SmallMoleculeDrug |
| Q92887 | DB00650 | Leucovorin | SmallMoleculeDrug |
| Q92887 | DB00661 | Verapamil | SmallMoleculeDrug |
| Q92887 | DB00675 | Tamoxifen | SmallMoleculeDrug |
| Q92887 | DB00688 | Mycophenolate mofetil | SmallMoleculeDrug |
| Q92887 | DB00694 | Daunorubicin | SmallMoleculeDrug |
| Q92887 | DB00695 | Furosemide | SmallMoleculeDrug |
| Q92887 | DB00709 | Lamivudine | SmallMoleculeDrug |
| Q92887 | DB00762 | Irinotecan | SmallMoleculeDrug |
| Q92887 | DB00773 | Etoposide | SmallMoleculeDrug |
| Q92887 | DB00795 | Sulfasalazine | SmallMoleculeDrug |
| Q92887 | DB00876 | Eprosartan | SmallMoleculeDrug |
| Q92887 | DB00908 | Quinidine | SmallMoleculeDrug |
| Q92887 | DB00957 | Norgestimate | SmallMoleculeDrug |
| Q92887 | DB00958 | Carboplatin | SmallMoleculeDrug |
| Q92887 | DB00966 | Telmisartan | SmallMoleculeDrug |
| Q92887 | DB00973 | Ezetimibe | SmallMoleculeDrug |
| Q92887 | DB00977 | Ethinyl Estradiol | SmallMoleculeDrug |
| Q92887 | DB00978 | Lomefloxacin | SmallMoleculeDrug |
| Q92887 | DB00997 | Doxorubicin | SmallMoleculeDrug |
| Q92887 | DB01016 | Glyburide | SmallMoleculeDrug |
| Q92887 | DB01032 | Probenecid | SmallMoleculeDrug |
| Q92887 | DB01045 | Rifampicin | SmallMoleculeDrug |
| Q92887 | DB01076 | Atorvastatin | SmallMoleculeDrug |
| Q92887 | DB01115 | Nifedipine | SmallMoleculeDrug |
| Q92887 | DB01138 | Sulfinpyrazone | SmallMoleculeDrug |
| Q92887 | DB01165 | Ofloxacin | SmallMoleculeDrug |
| Q92887 | DB01169 | Arsenic trioxide | SmallMoleculeDrug |
| Q92887 | DB01174 | Phenobarbital | SmallMoleculeDrug |
| Q92887 | DB01202 | Levetiracetam | SmallMoleculeDrug |
| Q92887 | DB01208 | Sparfloxacin | SmallMoleculeDrug |
| Q92887 | DB01229 | Paclitaxel | SmallMoleculeDrug |
| Q92887 | DB01232 | Saquinavir | SmallMoleculeDrug |
| Q92887 | DB01234 | Dexamethasone | SmallMoleculeDrug |
| Q92887 | DB01248 | Docetaxel | SmallMoleculeDrug |
| Q92887 | DB01268 | Sunitinib | SmallMoleculeDrug |
| Q92887 | DB01411 | Pranlukast | SmallMoleculeDrug |
| Q92887 | DB01586 | Ursodeoxycholic acid | SmallMoleculeDrug |
| Q92887 | DB02659 | Cholic Acid | SmallMoleculeDrug |
| Q92887 | DB02703 | Fusidic Acid | SmallMoleculeDrug |
| Q92887 | DB08860 | Pitavastatin | SmallMoleculeDrug |
| Q92887 | DB08884 | Gadoxetate | SmallMoleculeDrug |
| Q92887 | DB08907 | Canagliflozin | SmallMoleculeDrug |
| Q92887 | DB09060 | Avibactam | SmallMoleculeDrug |
| Q92887 | DB09272 | Eluxadoline | SmallMoleculeDrug |