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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
ABCC2 1244 ATP-binding cassette, sub-family C (CFTR/MRP), member 2  10DJS, MRP2, cMRP 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
25793771   2015Cell line : -

Source : The KAM cohort is based on the screening group of the Norwegian Colorectal Cancer Prevention study in Telemark, and enriched by a series of clinical CRC cases operated at Telemark Hospital (Skien) and Oslo University Hospital.

Sample Type : -

No. of Sample : -

Stage : -

real time RT-PCRUp-regulation-This study found that ABCC2 and ABCG2 expression levels were altered already in mild/moderate dysplasia in carcinogenesis suggesting that these ABC transporters are involved in the early steps of carcinogenesis


Gene Details



NC_000010.10 (101542457..101611662)

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Gene Type protein coding
Gene Family ATP binding cassette transporters / subfamily C
Description The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. [provided by RefSeq, Jul 2008]  
Chromosome 10
Location 10q24
Start 101542457  
End 101611662  
Strand +  
Gene Sequence

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Length 69206  
OMIM ID 601107   
HGNC ID HGNC:53   
Unigene ID Hs.368243   
Ensembl ID ENSG00000023839   
PharmGKB ID PA116   

mRNA Information


mRNA ID NM_000392.4
Exon join(1..280,2011..2184,9637..9762,10954..11088, 11295..11402,11816..11871,14500..14734,16610..16773, 17789..17966,21422..21676,22785..22850,24787..24924, 25486..25632,27537..27621,28939..29005,30421..30547, 34711..34887,36193..36360,36492..36672,47710..47836, 48119..48254,49014..49233,49380..49534,51783..51938, 53494..53693,59370..59496,61202..61303,61725..61868, 63027..63185,64364..64530,68005..68199,68905..69595)  
mRNA Sequence

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Length 5446  



CDS Information


   
Location248..4885
CDS Sequence

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CCDS ID CCDS7484.1



Protein Information


      
Protein IDNP_000383.1
Protein NameATP-binding cassette, sub-family C (CFTR/MRP), member 2
Molecular Wt. (Da)174061
Protein Sequence

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Length 1545  
Uniprot IDQ96BI1
Ensembl Protein ID ENSP00000311139  



Post-translational Modification Information (Source : HPRD)


Residue Type site
SPhosphorylation283
TPhosphorylation873
SPhosphorylation878
YPhosphorylation885
SPhosphorylation900
YPhosphorylation616
SPhosphorylation602
SPhosphorylation609
SPhosphorylation938
TPhosphorylation723
TPhosphorylation1378

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

                                             
Interactant Gene ID (Source: HPRD) Gene Symbol HPRD ID Ref Seq ID Technique References
821CANX252NP_001737.1in vivo12222674   
5962RDX1534NP_002897.1in vitro12068294   
79849PDZD36191NP_079067.2in vitro12615054   


Pathway Information


            
Pathway Name Pathway ID
ABC transporters hsa02010
Bile secretion hsa04976


Structure Information


No matching records could be found.

Domain Information




ID Location Description
cd032441298-1518  ABCC_MRP_domain2
cl214551298-1518  P-loop_NTPase superfamily
cd03250637-838  ABCC_MRP_domain1
cl21455637-838  P-loop_NTPase superfamily
cd033691294-1518  ABCC_NFT1
cd032881298-1528  ABCC_SUR2
cd032541298-1526  ABCC_Glucan_exporter_like
cd032511300-1522  ABCC_MsbA
cd032531300-1531  ABCC_ATM1_transporter
cd03290637-838  ABCC_SUR1_N
cd032491300-1535  ABC_MTABC3_MDL1_MDL2
cd032281300-1511  ABCC_MRP_Like
cd032521300-1531  ABCC_Hemolysin
cd03291654-862  ABCC_CFTR1
cd032451298-1513  ABCC_bacteriocin_exporters
cd032891298-1522  ABCC_CFTR2
cd032481297-1512  ABCC_TAP
cd03251639-857  ABCC_MsbA
cd03254638-853  ABCC_Glucan_exporter_like
cd03228637-837  ABCC_MRP_Like
cd03253638-857  ABCC_ATM1_transporter
cd03245638-843  ABCC_bacteriocin_exporters
cd03249655-860  ABC_MTABC3_MDL1_MDL2
pfam00664322-593  ABC_membrane
cl00549322-593  ABC_membrane superfamily
cd032461300-1512  ABCC_Protease_Secretion
pfam00664976-1256  ABC_membrane
cl00549976-1256  ABC_membrane superfamily
cd032471300-1516  ABCC_cytochrome_bd
cd03244637-844  ABCC_MRP_domain2
cd03235654-840  ABC_Metallic_Cations
cd03252639-856  ABCC_Hemolysin
cd03246643-839  ABCC_Protease_Secretion
pfam000051317-1465  ABC_tran
cd03293637-841  ABC_NrtD_SsuB_transporters
cd032571300-1516  ABC_NikE_OppD_transporters
cd032611316-1528  ABC_Org_Solvent_Resistant
cd032251301-1511  ABC_cobalt_CbiO_domain1
cd002671306-1511  ABC_ATPase
cd032141316-1516  ABC_Iron-Siderophores_B12_Hemin
cd03225638-838  ABC_cobalt_CbiO_domain1
cd032991314-1540  ABC_ModC_like
pfam00005654-789  ABC_tran
cd03247637-843  ABCC_cytochrome_bd
cd03214654-843  ABC_Iron-Siderophores_B12_Hemin
cd032191316-1520  ABC_Mj1267_LivG_branched
cd032581316-1526  ABC_MetN_methionine_transporter
cd032601316-1521  ABC_PstB_phosphate_transporter
cd03259649-843  ABC_Carb_Solutes_like
cd032561300-1521  ABC_PhnC_transporter
cd032501300-1511  ABCC_MRP_domain1
cd032291316-1511  ABC_Class3
cd03257654-843  ABC_NikE_OppD_transporters
cd03255643-839  ABC_MJ0796_LolCDE_FtsE
cd032591316-1516  ABC_Carb_Solutes_like
cd00267638-838  ABC_ATPase
cd032241316-1523  ABC_TM1139_LivF_branched
cd03261655-850  ABC_Org_Solvent_Resistant
cd032351301-1512  ABC_Metallic_Cations
cd03260643-844  ABC_PstB_phosphate_transporter
cd03230654-839  ABC_DR_subfamily_A
cd032631308-1521  ABC_subfamily_A
cd03229654-838  ABC_Class3
cd03248638-839  ABCC_TAP
cd03295639-850  ABC_OpuCA_Osmoprotection
cd032301316-1512  ABC_DR_subfamily_A
cd032161316-1513  ABC_Carb_Monos_I
cd032921300-1512  ABC_FtsE_transporter
cd03258654-851  ABC_MetN_methionine_transporter
cd03262655-839  ABC_HisP_GlnQ
cd03226643-840  ABC_cobalt_CbiO_domain2
cd03299650-843  ABC_ModC_like
cd032621300-1512  ABC_HisP_GlnQ
cd032551316-1512  ABC_MJ0796_LolCDE_FtsE
cd03224654-850  ABC_TM1139_LivF_branched
cd032941332-1525  ABC_Pro_Gly_Betaine
cd03369649-844  ABCC_NFT1
cd03301653-843  ABC_MalK_N
cd03296654-844  ABC_CysA_sulfate_importer
cd032641300-1516  ABC_drug_resistance_like
cd03294635-836  ABC_Pro_Gly_Betaine
cd03256645-848  ABC_PhnC_transporter
cd03297656-843  ABC_ModC_molybdenum_transporter
cd032261315-1513  ABC_cobalt_CbiO_domain2
cd032231300-1494  ABCD_peroxisomal_ALDP
cd03288637-861  ABCC_SUR2
cd03220654-843  ABC_KpsT_Wzt
cd03216654-840  ABC_Carb_Monos_I
cd03263654-848  ABC_subfamily_A
cd032681316-1514  ABC_BcrA_bacitracin_resist
cd03300647-844  ABC_PotA_N
cd032981322-1516  ABC_ThiQ_thiamine_transporter
cd03268654-843  ABC_BcrA_bacitracin_resist
cd032951300-1527  ABC_OpuCA_Osmoprotection
cd03234656-794  ABCG_White
cd03298656-843  ABC_ThiQ_thiamine_transporter
cd03289637-865  ABCC_CFTR2
cd032931300-1514  ABC_NrtD_SsuB_transporters
cd032131316-1516  ABCG_EPDR
cd032661300-1516  ABC_NatA_sodium_exporter
cd03219654-850  ABC_Mj1267_LivG_branched
cd032181316-1523  ABC_YhbG
cd032651317-1521  ABC_DrrA
TIGR011891314-1486  ccmA
cd032901317-1510  ABCC_SUR1_N
cd03218654-792  ABC_YhbG
cd03292637-820  ABC_FtsE_transporter
cd03223649-792  ABCD_peroxisomal_ALDP
cd032151313-1512  ABC_Carb_Monos_II
cd03213654-843  ABCG_EPDR
cd03221638-838  ABCF_EF-3
cd032971328-1513  ABC_ModC_molybdenum_transporter
cd032201316-1516  ABC_KpsT_Wzt
cd03217654-853  ABC_FeS_Assembly
cd03265649-844  ABC_DrrA
cd032961317-1530  ABC_CysA_sulfate_importer
cd033001314-1525  ABC_PotA_N
cd03269654-843  ABC_putative_ATPase
cd03264654-843  ABC_drug_resistance_like
TIGR01189645-828  ccmA
cd03215652-839  ABC_Carb_Monos_II
cd032671316-1513  ABC_NatA_like
cd03231645-793  ABC_CcmA_heme_exporter
cd032171316-1524  ABC_FeS_Assembly
cd03267644-843  ABC_NatA_like
cd03266654-843  ABC_NatA_sodium_exporter
cd033011316-1516  ABC_MalK_N
cd032691300-1513  ABC_putative_ATPase
cd032341315-1516  ABCG_White
cd032911302-1521  ABCC_CFTR1
cd03237660-864  ABC_RNaseL_inhibitor_domain2
cd03271654-844  ABC_UvrA_II
cd032311316-1486  ABC_CcmA_heme_exporter
cd03222660-853  ABC_RNaseL_inhibitor
cd032371323-1508  ABC_RNaseL_inhibitor_domain2
cd032211300-1511  ABCF_EF-3
cd03238654-838  ABC_UvrA
cd03227648-834  ABC_Class2
PRK13540646-820  PRK13540
pfam019261329-1420  MMR_HSR1
cd01131666-704  PilT
cd00880668-693  Era_like
cd03232656-793  ABCG_PDR_domain2
TIGR009578-1537  MRP_assoc_pro
PLN03130198-1523  PLN03130
PLN0323223-1539  PLN03232
PTZ00243310-1521  PTZ00243
TIGR01271198-1522  CFTR_protein
COG1132970-1534  MdlB
COG2274961-1529  SunT
COG1132310-857  MdlB
TIGR022031030-1522  MsbA_lipidA
TIGR022041056-1529  MsbA_rel
PRK107901029-1531  PRK10790
COG2274304-857  SunT
COG49881051-1534  CydD
TIGR009581031-1531  3a01208
TIGR018461056-1531  type_I_sec_HlyB
COG49871077-1531  CydC
COG52651049-1526  ATM1
PRK136571106-1537  PRK13657
TIGR033751267-1523  type_I_sec_LssB
TIGR037971065-1533  NHLM_micro_ABC2
TIGR011931061-1529  bacteriocin_ABC
PRK111761056-1522  PRK11176
TIGR011921110-1537  chvA
COG4988361-861  CydD
PRK111741328-1531  PRK11174
TIGR037961059-1528  NHLM_micro_ABC1
TIGR03375448-851  type_I_sec_LssB
TIGR028571285-1507  CydD
TIGR028681077-1495  CydC
PRK11174657-869  PRK11174
PRK111601266-1529  PRK11160
TIGR02203340-856  MsbA_lipidA
TIGR02857636-834  CydD
COG4987391-855  CydC
TIGR01193504-857  bacteriocin_ABC
PRK11160636-857  PRK11160
TIGR02204654-857  MsbA_rel
COG11311300-1523  CcmA
TIGR01846417-857  type_I_sec_HlyB
COG1121649-840  ZnuC
PTZ00265754-1529  PTZ00265
PRK107891265-1526  PRK10789
COG11201300-1523  FepC
COG11351300-1525  AbcC
PRK13657622-878  PRK13657
TIGR01842653-851  type_I_sec_PrtD
PRK11176637-857  PRK11176
PRK10789643-853  PRK10789
COG5265445-857  ATM1
TIGR02868639-821  CydC
TIGR03797334-856  NHLM_micro_ABC2
TIGR018421316-1523  type_I_sec_PrtD
TIGR00958333-856  3a01208
COG11221300-1523  EcfA2
TIGR01192632-861  chvA
COG46181316-1523  ArpD
PRK10790503-855  PRK10790
COG4618653-851  ArpD
TIGR03796654-857  NHLM_micro_ABC1
COG11211300-1523  ZnuC
COG11241300-1525  DppF
COG11231315-1525  GsiA
COG1116654-841  TauB
COG1122643-852  EcfA2
COG1136655-842  LolD
COG4525637-842  TauB
TIGR00968654-844  3a0106s01
COG1131654-901  CcmA
COG1120654-844  FepC
COG11291316-1513  MglA
PRK136321300-1543  cbiO
COG1118652-844  CysA
COG04111316-1525  LivG
PTZ002651239-1509  PTZ00265
COG11231316-1525  GsiA
COG04101316-1522  LivF
TIGR03265654-844  PhnT2
COG38391300-1525  MalK
TIGR045201300-1523  ECF_ATPase_1
COG1123654-844  GsiA
COG3839654-844  MalK
COG3842654-844  PotA
COG1135654-881  AbcC
TIGR011861323-1525  proV
COG11271316-1536  MlaF
COG4608654-850  AppF
TIGR023151300-1521  ABC_phnC
TIGR021421323-1536  modC_ABC
COG1126655-865  GlnQ
PRK100701306-1529  PRK10070
COG11011311-1513  PhnK
COG46081305-1522  AppF
COG3840658-853  ThiQ
COG04441299-1525  DppD
COG41781297-1494  YddA
COG36381300-1521  PhnC
PRK136371317-1520  cbiO
TIGR00972654-844  3a0107s01c2
PRK10851656-844  PRK10851
COG11261316-1522  GlnQ
PRK111531300-1517  metN
PRK11248647-842  tauB
COG1124654-850  DppF
TIGR023141331-1525  ABC_MetN
COG11361316-1512  LolD
COG45591316-1522  COG4559
COG0488638-855  Uup
TIGR01186654-844  proV
TIGR02315654-848  ABC_phnC
COG1123654-851  GsiA
PRK136501300-1521  cbiO
COG1125654-859  OpuBA
PRK142501299-1525  PRK14250
PRK11264657-850  PRK11264
PLN03232418-876  PLN03232
PRK142441316-1525  PRK14244
TIGR04520643-844  ECF_ATPase_1
COG3638656-844  PhnC
COG4555654-854  NatA
COG1127655-850  MlaF
COG11251300-1525  OpuBA
COG41751317-1544  ProV
TIGR009721316-1525  3a0107s01c2
COG0410654-850  LivF
COG38421296-1525  PotA
PRK15056636-876  PRK15056
TIGR02314654-866  ABC_MetN
TIGR03258654-848  PhnT
PRK142461316-1525  PRK14246
TIGR011941027-1514  cyc_pep_trnsptr
COG1134655-844  TagH
PRK142621300-1525  PRK14262
COG4619654-804  FetA
COG45551317-1522  NatA
COG1117654-844  PstB
COG41721286-1525  YejF
TIGR045211317-1523  ECF_ATPase_2
TIGR027691316-1514  nickel_nikE
TIGR04521656-860  ECF_ATPase_2
COG41671328-1525  SapF
COG38451317-1521  YufO
PRK136361317-1522  cbiO
TIGR02142656-887  modC_ABC
PRK136481300-1521  cbiO
PRK14239653-822  PRK14239
TIGR03410655-848  urea_trans_UrtE
PRK14266649-843  PRK14266
COG4175654-851  ProV
PRK11432656-848  fbpC
PRK14250635-873  PRK14250
COG28841300-1520  FtsE
TIGR03608655-834  L_ocin_972_ABC
TIGR01277658-839  thiQ
PRK13632632-852  cbiO
PRK14255654-871  PRK14255
PRK136441300-1525  cbiO
TIGR011661316-1492  cbiO
TIGR03005647-843  ectoine_ehuA
COG4604654-844  CeuD
PRK142471299-1525  PRK14247
COG4148656-887  ModC
COG0488655-852  Uup
TIGR02982656-840  heterocyst_DevA
COG4559656-844  COG4559
COG46151045-1514  PvdE
PRK13635643-867  cbiO
PRK13539655-794  PRK13539
PRK13640634-844  cbiO
TIGR011871332-1525  potA
PRK136351299-1523  cbiO
PRK14259649-873  PRK14259
PRK136331315-1521  PRK13633
COG0444654-849  DppD
PRK112311316-1523  fecE
TIGR04406654-792  LPS_export_lptB
COG11181299-1543  CysA
PRK136401332-1538  cbiO
PRK136421300-1522  cbiO
PRK10771658-850  thiQ
PRK14257613-843  PRK14257
PRK14243654-873  PRK14243
PRK142511317-1525  PRK14251
PRK135481316-1523  hmuV
PRK14240655-851  PRK14240
COG1129654-840  MglA
TIGR034101316-1521  urea_trans_UrtE
PRK094931300-1525  glnQ
COG41481313-1525  ModC
PRK142421295-1526  PRK14242
COG11341308-1524  TagH
COG11171316-1525  PstB
PRK09452649-844  potA
PRK13548654-844  hmuV
TIGR009681316-1531  3a0106s01
PRK14263654-823  PRK14263
PRK14254648-841  PRK14254
PRK09493656-865  glnQ
PRK13648632-843  cbiO
PRK136521316-1525  cbiO
TIGR01187669-844  potA
PRK13646637-857  cbiO
PRK150791319-1525  PRK15079
TIGR011881317-1521  drrA
COG04881300-1513  Uup
PRK142581300-1498  PRK14258
COG0411654-850  LivG
COG11161316-1514  TauB
PRK136411300-1521  cbiO
PRK14244648-844  PRK14244
TIGR03415654-868  ABC_choXWV_ATP
PRK14272654-849  PRK14272
PRK095361316-1522  btuD
PRK142401297-1525  PRK14240
COG38401321-1522  ThiQ
COG4161650-865  ArtP
TIGR032581298-1540  PhnT
COG4598655-843  HisP
COG46191306-1525  FetA
COG4172644-859  YejF
COG1137654-792  LptB
PRK14242649-854  PRK14242
COG11371316-1525  LptB
COG4133647-838  CcmA
TIGR038731315-1522  F420-0_ABC_ATP
COG2884655-845  FtsE
PRK142661316-1525  PRK14266
PRK142451317-1526  PRK14245
PRK11231654-844  fecE
TIGR044061316-1522  LPS_export_lptB
PRK11153654-844  metN
COG4167654-850  SapF
PRK11607645-845  potG
COG4181655-841  YbbA
PRK13634656-858  cbiO
TIGR01288654-849  nodI
PRK14251657-849  PRK14251
PLN03130657-868  PLN03130
TIGR038641316-1523  PQQ_ABC_ATP
PRK14265656-843  PRK14265
COG4615318-841  PvdE
PRK11247655-793  ssuB
PRK14258643-843  PRK14258
COG4178623-792  YddA
TIGR032691316-1521  met_CoM_red_A2
PRK142691320-1525  PRK14269
PRK10744655-792  pstB
COG1101649-840  PhnK
PRK142481320-1525  PRK14248
PRK154391316-1521  PRK15439
PRK14236649-822  PRK14236
PRK104191316-1514  nikE
TIGR01188654-853  drrA
COG41721316-1525  YejF
PRK11000655-843  PRK11000
TIGR02211657-841  LolD_lipo_ex
PRK14262643-851  PRK14262
PRK14274654-841  PRK14274
PRK136381308-1522  cbiO
PRK14267654-843  PRK14267
TIGR03771659-849  anch_rpt_ABC
TIGR030051300-1525  ectoine_ehuA
PRK09536654-849  btuD
TIGR032691319-1522  met_CoM_red_A2
PRK13637656-844  cbiO
PRK142681317-1525  PRK14268
PRK142551317-1545  PRK14255
PRK10247656-834  PRK10247
PRK14235649-822  PRK14235
PRK14253654-848  PRK14253
TIGR012771328-1512  thiQ
PRK13536642-849  PRK13536
PRK142541317-1525  PRK14254
PRK15112632-850  PRK15112
PRK108951316-1523  PRK10895
PRK13644649-850  cbiO
PRK142721331-1525  PRK14272
PRK142571293-1525  PRK14257
PRK13647634-860  cbiO
TIGR03873645-849  F420-0_ABC_ATP
PRK14270646-873  PRK14270
PTZ00265704-860  PTZ00265
TIGR00954654-801  3a01203
TIGR02673638-828  FtsE
TIGR011841317-1527  ntrCD
PRK14261648-873  PRK14261
PRK107711328-1523  thiQ
PRK13639643-844  cbiO
PRK09984657-844  PRK09984
PRK10070632-864  PRK10070
PRK142701332-1525  PRK14270
TIGR02769643-860  nickel_nikE
PRK113001315-1525  livG
PRK14241654-822  PRK14241
PRK116071328-1525  potG
PRK10619647-850  PRK10619
PRK151121330-1525  PRK15112
PTZ002431308-1525  PTZ00243
PRK142641314-1525  PRK14264
PRK14275649-849  PRK14275
PRK112471316-1512  ssuB
PRK142671316-1525  PRK14267
PRK11124656-865  artP
PRK136431300-1523  cbiO
PRK13645632-844  cbiO
PRK102611320-1525  PRK10261
PRK136391307-1521  cbiO
PRK135391314-1480  PRK13539
TIGR027701330-1526  nickel_nikD
PRK142601317-1525  PRK14260
PRK10535643-840  PRK10535
TIGR01184654-837  ntrCD
COG1129606-840  MglA
PRK105351316-1513  PRK10535
PRK142491316-1525  PRK14249
PRK14245646-873  PRK14245
PRK13537654-850  PRK13537
PRK142611317-1526  PRK14261
COG0396654-843  SufC
TIGR022111316-1514  LolD_lipo_ex
PRK10419622-841  nikE
TIGR02770654-844  nickel_nikD
PRK14238646-841  PRK14238
COG11291328-1512  MglA
PRK13642634-870  cbiO
PRK13651656-848  PRK13651
TIGR009541274-1494  3a01203
TIGR026331328-1512  xylG
COG04881277-1493  Uup
PRK107621333-1513  PRK10762
PRK14264645-843  PRK14264
PRK142391317-1525  PRK14239
PRK142711332-1525  PRK14271
TIGR03864654-853  PQQ_ABC_ATP
PRK135371300-1523  PRK13537
PRK142531317-1525  PRK14253
PRK11629654-823  lolD
TIGR026731300-1511  FtsE
PRK113081305-1525  dppF
PRK135361316-1522  PRK13536
PRK14252654-851  PRK14252
PRK14247654-843  PRK14247
PRK11614657-850  livF
COG4586647-853  COG4586
COG4136637-826  YnjD
PRK13633643-844  PRK13633
PRK14260632-792  PRK14260
COG1119656-831  ModF
PRK135491328-1512  PRK13549
TIGR03719655-852  ABC_ABC_ChvD
TIGR037711328-1522  anch_rpt_ABC
PRK097001317-1510  PRK09700
PRK112641316-1525  PRK11264
PRK107441290-1525  pstB
COG41331314-1474  CcmA
PRK135491317-1513  PRK13549
PRK154391318-1512  PRK15439
TIGR036081316-1475  L_ocin_972_ABC
COG46041306-1523  CeuD
PRK142351317-1525  PRK14235
COG41811316-1514  YbbA
PRK14268646-823  PRK14268
TIGR035221316-1523  GldA_ABC_ATP
COG45861307-1527  COG4586
PRK142371333-1525  PRK14237
PRK142521295-1525  PRK14252
PRK094731328-1525  oppD
PRK095441316-1519  znuC
PRK10895654-792  PRK10895
TIGR012881315-1523  nodI
PRK13643637-846  cbiO
PRK14249654-792  PRK14249
PRK151341316-1529  PRK15134
PRK14248654-843  PRK14248
PRK102471332-1507  PRK10247
TIGR012571333-1544  rim_protein
PRK10522575-841  PRK10522
COG11191285-1513  ModF
PRK106191316-1525  PRK10619
COG4152654-881  YhaQ
PRK14246649-844  PRK14246
PRK116141316-1513  livF
COG38451317-1520  YufO
PRK102611328-1525  PRK10261
PRK105751331-1523  PRK10575
COG45981316-1525  HisP
PRK14256654-843  PRK14256
PRK142361316-1525  PRK14236
TIGR037401315-1513  galliderm_ABC
TIGR01257654-836  rim_protein
TIGR02324654-793  CP_lyasePhnL
PRK13650643-889  cbiO
PRK142751317-1525  PRK14275
COG41381300-1525  BtuD
PRK108511316-1525  PRK10851
TIGR00955664-844  3a01204
PRK136341300-1525  cbiO
COG03961316-1524  SufC
PRK142561299-1525  PRK14256
PRK105221289-1514  PRK10522
PRK136451332-1541  cbiO
TIGR01194657-841  cyc_pep_trnsptr
PRK14273654-861  PRK14273
TIGR01978655-853  sufC
PRK114321325-1545  fbpC
COG4172643-850  YejF
TIGR032651301-1528  PhnT2
TIGR029821316-1512  heterocyst_DevA
TIGR023231318-1525  CP_lyasePhnK
PRK136461299-1521  cbiO
PRK142381296-1525  PRK14238
PRK11144656-792  modC
COG3845655-840  YufO
PRK111441313-1520  modC
PRK13409661-790  PRK13409
TIGR03269645-862  met_CoM_red_A2
PRK142731331-1545  PRK14273
PRK13538655-794  PRK13538
PRK15439657-844  PRK15439
PRK142651315-1496  PRK14265
PRK10253643-844  PRK10253
PRK13641656-852  cbiO
TIGR026331315-1513  xylG
COG41611316-1517  ArtP
PRK142431315-1525  PRK14243
COG1245660-833  Rli1
COG41521316-1544  YhaQ
PRK11650645-793  ugpC
COG46741332-1521  COG4674
PRK142591317-1495  PRK14259
PRK102531332-1522  PRK10253
PRK036951321-1522  PRK03695
PRK11308651-851  dppF
PRK10261654-848  PRK10261
PRK110001318-1525  PRK11000
PRK13543645-828  PRK13543
PRK14237649-822  PRK14237
PRK142741317-1525  PRK14274
PRK136311332-1521  cbiO
PRK09544656-834  znuC
PRK13631656-844  cbiO
TIGR034151319-1525  ABC_choXWV_ATP
PRK136491317-1523  cbiO
PRK136471300-1522  cbiO
PRK10575663-849  PRK10575
PRK142631331-1525  PRK14263
PRK094521316-1540  potA
TIGR03411654-844  urea_trans_UrtD
PRK10418654-850  nikD
PRK109821332-1513  PRK10982
PRK09580649-854  sufC
PRK14269656-823  PRK14269
PRK111241316-1516  artP
PRK10584657-841  PRK10584
PRK15079654-848  PRK15079
PRK135381315-1508  PRK13538
PRK13652643-844  cbiO
PRK099841317-1521  PRK09984
PLN03073637-839  PLN03073
PRK09700654-843  PRK09700
TIGR03522651-850  GldA_ABC_ATP
COG3845654-840  YufO
PRK112881331-1514  araG
PRK15064649-787  PRK15064
PRK135471316-1523  hmuV
COG2401655-841  MK0520
PRK15134762-850  PRK15134
PRK14271608-857  PRK14271
TIGR02323655-843  CP_lyasePhnK
smart00382664-825  AAA
PRK13545656-857  tagH
COG4778654-793  PhnL
PRK13636634-852  cbiO
TIGR009551308-1523  3a01204
PRK142411333-1525  PRK14241
TIGR034111423-1521  urea_trans_UrtD
PRK097001328-1514  PRK09700
PRK10908646-822  PRK10908
TIGR00630754-844  uvra
PRK109821317-1524  PRK10982
PLN03073762-858  PLN03073
TIGR009561328-1530  3a01205
PRK134091328-1508  PRK13409
PRK109081317-1512  PRK10908
smart003821328-1510  AAA
COG12451328-1522  Rli1
PRK105841316-1514  PRK10584
COG0178761-864  UvrA
PRK11147654-706  PRK11147
COG01781437-1526  UvrA
PRK15134761-850  PRK15134
PRK151341308-1525  PRK15134
TIGR009561304-1510  3a01205
TIGR01257608-822  rim_protein
PRK11701655-696  phnK
PRK03695657-792  PRK03695
PRK107621328-1512  PRK10762
PLN032111316-1511  PLN03211
PRK136511316-1522  PRK13651
TIGR02633657-793  xylG
TIGR006301437-1521  uvra
PRK150931437-1525  PRK15093


Ontology Information


   
HPRD ID3685
Molecular ClassTransport/cargo protein
Molecular FunctionTranscription regulator activity (GO:0030528); DNA binding (GO:0003677)
Biological ProcessRegulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219)  



SNP Information


View SNP Geneview Report   

Drug Information


Uniprot ID DrugBank ID Name Type
Q92887DB00171Adenosine triphosphateSmallMoleculeDrug
Q92887DB01138SulfinpyrazoneSmallMoleculeDrug
Q92887DB00067VasopressinBiotechDrug
Q92887DB00091CyclosporineSmallMoleculeDrug
Q92887DB00116Tetrahydrofolic acidSmallMoleculeDrug
Q92887DB00143GlutathioneSmallMoleculeDrug
Q92887DB00175PravastatinSmallMoleculeDrug
Q92887DB00206ReserpineSmallMoleculeDrug
Q92887DB00224IndinavirSmallMoleculeDrug
Q92887DB00227LovastatinSmallMoleculeDrug
Q92887DB00252PhenytoinSmallMoleculeDrug
Q92887DB00257ClotrimazoleSmallMoleculeDrug
Q92887DB00275OlmesartanSmallMoleculeDrug
Q92887DB00286Conjugated EstrogensSmallMoleculeDrug
Q92887DB00300TenofovirSmallMoleculeDrug
Q92887DB00328IndomethacinSmallMoleculeDrug
Q92887DB00345AminohippurateSmallMoleculeDrug
Q92887DB00398SorafenibSmallMoleculeDrug
Q92887DB00421SpironolactoneSmallMoleculeDrug
Q92887DB00503RitonavirSmallMoleculeDrug
Q92887DB00515CisplatinSmallMoleculeDrug
Q92887DB00526OxaliplatinSmallMoleculeDrug
Q92887DB00541VincristineSmallMoleculeDrug
Q92887DB00563MethotrexateSmallMoleculeDrug
Q92887DB00564CarbamazepineSmallMoleculeDrug
Q92887DB00570VinblastineSmallMoleculeDrug
Q92887DB00602IvermectinSmallMoleculeDrug
Q92887DB00641SimvastatinSmallMoleculeDrug
Q92887DB00650LeucovorinSmallMoleculeDrug
Q92887DB00661VerapamilSmallMoleculeDrug
Q92887DB00675TamoxifenSmallMoleculeDrug
Q92887DB00688Mycophenolate mofetilSmallMoleculeDrug
Q92887DB00694DaunorubicinSmallMoleculeDrug
Q92887DB00695FurosemideSmallMoleculeDrug
Q92887DB00709LamivudineSmallMoleculeDrug
Q92887DB00762IrinotecanSmallMoleculeDrug
Q92887DB00773EtoposideSmallMoleculeDrug
Q92887DB00795SulfasalazineSmallMoleculeDrug
Q92887DB00876EprosartanSmallMoleculeDrug
Q92887DB00908QuinidineSmallMoleculeDrug
Q92887DB00957NorgestimateSmallMoleculeDrug
Q92887DB00958CarboplatinSmallMoleculeDrug
Q92887DB00966TelmisartanSmallMoleculeDrug
Q92887DB00973EzetimibeSmallMoleculeDrug
Q92887DB00977Ethinyl EstradiolSmallMoleculeDrug
Q92887DB00978LomefloxacinSmallMoleculeDrug
Q92887DB00997DoxorubicinSmallMoleculeDrug
Q92887DB01016GlyburideSmallMoleculeDrug
Q92887DB01032ProbenecidSmallMoleculeDrug
Q92887DB01045RifampicinSmallMoleculeDrug
Q92887DB01076AtorvastatinSmallMoleculeDrug
Q92887DB01115NifedipineSmallMoleculeDrug
Q92887DB01138SulfinpyrazoneSmallMoleculeDrug
Q92887DB01165OfloxacinSmallMoleculeDrug
Q92887DB01169Arsenic trioxideSmallMoleculeDrug
Q92887DB01174PhenobarbitalSmallMoleculeDrug
Q92887DB01202LevetiracetamSmallMoleculeDrug
Q92887DB01208SparfloxacinSmallMoleculeDrug
Q92887DB01229PaclitaxelSmallMoleculeDrug
Q92887DB01232SaquinavirSmallMoleculeDrug
Q92887DB01234DexamethasoneSmallMoleculeDrug
Q92887DB01248DocetaxelSmallMoleculeDrug
Q92887DB01268SunitinibSmallMoleculeDrug
Q92887DB01411PranlukastSmallMoleculeDrug
Q92887DB01586Ursodeoxycholic acidSmallMoleculeDrug
Q92887DB02659Cholic AcidSmallMoleculeDrug
Q92887DB02703Fusidic AcidSmallMoleculeDrug
Q92887DB08860PitavastatinSmallMoleculeDrug
Q92887DB08884GadoxetateSmallMoleculeDrug
Q92887DB08907CanagliflozinSmallMoleculeDrug
Q92887DB09060AvibactamSmallMoleculeDrug
Q92887DB09272EluxadolineSmallMoleculeDrug

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO