Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| TRIM29 | 23650 | tripartite motif containing 29  | 11 | ATDC, FLJ36085  |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 24078150    | 2013 | Cell line : - Source : - Sample Type : CRC tumor and normal tissue No. of Sample : 203 cases of primary colorectal cancer paired with non-cancerous tissues. Stage : - | real time RT-PCR, Tissue microarray and immunohistochemistry | Up-regulation | - | TRIM29 may serve as a novel biomarker for tumor recurrence and survival for colorectal cancer patients. TRIM29 expression was much higher in colorectal cancer tissues and significantly associated with the depth of tumor invasion, lymph node metastasis, distant metastasis, histological differentiation, vascular invasion, ki-67 index, and advanced tumor stage |
Gene Details

| Gene Type | protein coding |
|---|---|
| Gene Family | Tripartite motif containing / Tripartite motif containing |
| Description | The protein encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype.   |
| Chromosome | 11 |
| Location | 11q23.3 |
| Start | 120111286   |
| End | 120185423   |
| Strand | -   |
| Gene Sequence |    Download   Select all |
| Length | 74138   |
| OMIM ID | 610658    |
| HGNC ID | HGNC:17274    |
| Unigene ID | Hs.504115    |
| Ensembl ID | ENSG00000137699    |
| PharmGKB ID | -    |
mRNA Information
| mRNA ID | XM_011542731.1 |
|---|---|
| Exon | join(1..174,47279..48196,56929..57024,57855..58088, 59535..59733,62369..62470,64759..64851,67103..67201, 68364..68465,70010..70086,72948..74138)   | mRNA Sequence |    Download   Select all |
| Length | 3037   |
CDS Information
| Location | join(47393..48196,56929..57024,57855..58088,59535..59733, 62369..62470,64759..64851,67103..67201,70010..70086, 72948..73010) |
|---|---|
| CDS Sequence |    Download   Select all |
| CCDS ID | CCDS8428.1 |    
Protein Information
| Protein ID | NP_036233.2 |
|---|---|
| Protein Name | tripartite motif containing 29 |
| Molecular Wt. (Da) | 65704 |
| Protein Sequence |    Download   Select all |
| Length | 588   |
| Uniprot ID | P10721 |    
| Ensembl Protein ID | ENSP00000288135   |    
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 21 |
| S | Phosphorylation | 21 |
| S | Phosphorylation | 23 |
| S | Phosphorylation | 23 |
| S | Phosphorylation | 104 |
| S | Phosphorylation | 104 |
| T | Phosphorylation | 476 |
| T | Phosphorylation | 476 |
| S | Phosphorylation | 489 |
| S | Phosphorylation | 489 |
| S | Phosphorylation | 58 |
| S | Phosphorylation | 58 |
| Y | Phosphorylation | 93 |
| Y | Phosphorylation | 93 |
| S | Phosphorylation | 488 |
| S | Phosphorylation | 488 |
| S | Phosphorylation | 7 |
| S | Phosphorylation | 12 |
| S | Phosphorylation | 7 |
| S | Phosphorylation | 12 |
| S | Phosphorylation | 9 |
| S | Phosphorylation | 9 |
| S | Phosphorylation | 13 |
| S | Phosphorylation | 13 |
| S | Phosphorylation | 26 |
| S | Phosphorylation | 28 |
| T | Phosphorylation | 33 |
| S | Phosphorylation | 26 |
| S | Phosphorylation | 28 |
| T | Phosphorylation | 33 |
| S | Phosphorylation | 95 |
| S | Phosphorylation | 95 |
| Y | Phosphorylation | 474 |
| Y | Phosphorylation | 474 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING)      View   
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 373 |    TRIM23 |    3449 |    NP_001647.1 |    yeast 2-hybrid |    11331580    |
| 3094 |    HINT1 |    3204 |    NP_005331.1 |    in vitro |    7644499    |
| 4093 |    SMAD9 |    4484 |    BAA21128.1 |    yeast 2-hybrid |    15231748    |
| 5578 |    PRKCA |    1498 |    NP_002728.1 |    in vitro;yeast 2-hybrid |    7644499    |
| 7431 |    VIM |    1899 |    NP_003371.2 |    in vitro;yeast 2-hybrid |    7644499    |
| 9832 |    JAKMIP2 |    11090 |    NP_055605.2 |    yeast 2-hybrid |    16189514    |
| 11043 |    MID2 |    2191 |    NP_036348.2 |    yeast 2-hybrid |    11331580    |
| 80321 |    CEP70 |    16779 |    NP_077817.2 |    yeast 2-hybrid |    16189514    |
| 81559 |    TRIM11 |    7429 |    NP_660215.1 |    yeast 2-hybrid |    11331580    |
| 84445 |    LZTS2 |    14341 |    NP_115805.1 |    yeast 2-hybrid |    16189514    |
| 85302 |    FBF1 |    10948 |    NP_001074011.1 |    yeast 2-hybrid |    16189514    |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00021 | 223-260  | BBOX |
| cl00034 | 223-260  | BBOX superfamily |
| smart00336 | 220-260  | BBOX |
| pfam00643 | 220-260  | zf-B_box |
| pfam03938 | 272-355  | OmpH |
| cl21485 | 272-355  | OmpH superfamily |
| smart00935 | 273-355  | OmpH |
| pfam05615 | 271-366  | THOC7 |
| cl09577 | 271-366  | THOC7 superfamily |
| pfam00435 | 287-366  | Spectrin |
| cl02488 | 287-366  | SPEC superfamily |
| pfam13868 | 273-362  | Trichoplein |
| TIGR02168 | 276-366  | SMC_prok_B |
| pfam07888 | 271-372  | CALCOCO1 |
| COG1579 | 271-379  | COG1579 |
| TIGR02168 | 271-367  | SMC_prok_B |
| COG0419 | 271-367  | SbcC |
Ontology Information
| HPRD ID | 1970 |    
|---|---|
| Molecular Class | Transcription regulatory protein |
| Molecular Function | Protease inhibitor activity (GO:0030414) |
| Biological Process | Protein metabolism (GO:0019538)   |
Drug Information
No matching records could be found.
External Links
| ArrayExpress | GO |    
|---|---|
| ICGC | GO |    
| Cancer3D | GO |    
| COSMIC | GO |    
| NCG | GO |    
| TSGene | GO |    
| Tumor Gene Family of Databases | GO |    
| CCDB | GO |    
| G2SBC | GO |    
| Osteosarcoma Database | GO |    
| RCDB | GO |    
